JP2015521206A5 - - Google Patents
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- Publication number
- JP2015521206A5 JP2015521206A5 JP2015515530A JP2015515530A JP2015521206A5 JP 2015521206 A5 JP2015521206 A5 JP 2015521206A5 JP 2015515530 A JP2015515530 A JP 2015515530A JP 2015515530 A JP2015515530 A JP 2015515530A JP 2015521206 A5 JP2015521206 A5 JP 2015521206A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- peptide
- isolated
- har
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 23
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 239000004471 Glycine Substances 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000568 immunological adjuvant Substances 0.000 claims 1
- 239000012678 infectious agent Substances 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261656256P | 2012-06-06 | 2012-06-06 | |
| US61/656,256 | 2012-06-06 | ||
| PCT/EP2013/061751 WO2013182661A1 (en) | 2012-06-06 | 2013-06-06 | Peptides derived from viral proteins for use as immunogens and dosage reactants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015521206A JP2015521206A (ja) | 2015-07-27 |
| JP2015521206A5 true JP2015521206A5 (https=) | 2016-08-12 |
| JP6310909B2 JP6310909B2 (ja) | 2018-04-11 |
Family
ID=48577073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515530A Expired - Fee Related JP6310909B2 (ja) | 2012-06-06 | 2013-06-06 | 免疫原及び投薬反応物として使用するためのウイルスタンパク質に由来するペプチド |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10501499B2 (https=) |
| EP (1) | EP2859011B1 (https=) |
| JP (1) | JP6310909B2 (https=) |
| KR (1) | KR20150018870A (https=) |
| CN (1) | CN104619718A (https=) |
| AU (1) | AU2013273482A1 (https=) |
| BR (1) | BR112014030466A2 (https=) |
| CA (1) | CA2874923C (https=) |
| EA (1) | EA201492262A1 (https=) |
| HK (1) | HK1207871A1 (https=) |
| IL (1) | IL235891A0 (https=) |
| IN (1) | IN2014KN02769A (https=) |
| MX (1) | MX2014014683A (https=) |
| NZ (1) | NZ702146A (https=) |
| WO (1) | WO2013182661A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10342846B2 (en) * | 2013-02-04 | 2019-07-09 | University Of Notre Dame Du Lac | Nanoparticle drug delivery systems |
| TW201609152A (zh) | 2014-09-03 | 2016-03-16 | 免疫原公司 | 包含細胞結合劑及細胞毒性劑之偶聯物 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| KR20190020098A (ko) * | 2016-06-20 | 2019-02-27 | 아이에스에이 파마슈티컬즈 비.브이. | 펩타이드 백신의 제형 |
| BR112019013724A2 (pt) * | 2017-01-03 | 2020-04-14 | Emergex Vaccines Holding Limited | composições de vacina influenza universal |
| CN110548136A (zh) * | 2018-05-30 | 2019-12-10 | 王美亮 | 汉坦病毒长肽疫苗 |
| CN113784989B (zh) * | 2019-03-25 | 2024-11-15 | 免疫功坊股份有限公司 | 带有金属结合区的复合多肽及其分子构建体 |
| KR102393872B1 (ko) * | 2019-08-28 | 2022-05-04 | 엠브릭스 주식회사 | 바이러스 외피를 손상시키는 m2 단백질 유래 항바이러스 펩타이드 및 그의 용도 |
| US20230109142A1 (en) * | 2020-02-14 | 2023-04-06 | Immunor As | Corona virus vaccine |
| KR102707584B1 (ko) * | 2020-04-02 | 2024-09-19 | 조선대학교산학협력단 | 코로나바이러스 감염증１９의 진단 및 백신을 위한 재조합 뉴클레오캡시드 단백질 및 이의 용도 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| JPS5896026A (ja) | 1981-10-30 | 1983-06-07 | Nippon Chemiphar Co Ltd | 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤 |
| EP0098110B1 (en) | 1982-06-24 | 1989-10-18 | NIHON CHEMICAL RESEARCH KABUSHIKI KAISHA also known as JAPAN CHEMICAL RESEARCH CO., LTD | Long-acting composition |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4606918A (en) | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4766106A (en) | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| CA1292686C (en) | 1986-10-27 | 1991-12-03 | Ze'ev Shaked | Pharmaceutical compositions of recombinant interleukin-2 and formulation process |
| CA1294215C (en) | 1986-10-27 | 1992-01-14 | Ze'ev Shaked | Pharmaceutical compositions of recombinant beta-interferon and formulation processes |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| WO1993001831A1 (en) | 1991-07-25 | 1993-02-04 | Idec Pharmaceuticals Corporation | Induction of cytotoxic t-lymphocyte responses |
| MA22842A1 (fr) | 1992-03-27 | 1993-10-01 | Smithkline Beecham Biolog | Procede de preparation de compositions de vaccin. |
| FI945483A7 (fi) | 1992-05-23 | 1995-01-20 | Smithkline Beecham Biologicals S A | Hepatiitti B - pinta-antigeenejä ja muita antigeenejä sisältäviä yhdistelmärokotteita |
| DK0671948T3 (da) | 1992-06-25 | 1997-09-01 | Smithkline Beecham Biolog | Vaccinepræparat indeholdende adjuvanser |
| ATE157882T1 (de) | 1993-03-23 | 1997-09-15 | Smithkline Beecham Biolog | 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen |
| AU698962B2 (en) | 1993-09-14 | 1998-11-12 | Epimmune, Inc. | Alteration of immune response using pan DR-binding peptides |
| EP0992580B1 (en) | 1993-11-04 | 2005-03-09 | Innogenetics N.V. | Immunodominant human T-cell epitopes of Hepatitis C virus |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5709995A (en) | 1994-03-17 | 1998-01-20 | The Scripps Research Institute | Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses |
| AU697171B2 (en) | 1994-04-08 | 1998-10-01 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Hepatitis C virus core peptide for stimulation of cytotoxic T lymphocytes and diagnosis of HCV exposure |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| DE69733352T2 (de) | 1996-03-21 | 2006-04-27 | Epimmune, Inc., San Diego | Hla-a2.1 bindende peptide und deren verwendung |
| CA2250723C (en) | 1996-05-24 | 2012-07-17 | Chiron Corporation | Multiple epitope fusion protein |
| US6566330B1 (en) | 1996-10-22 | 2003-05-20 | Medical University Of South Carolina Foundation Research Development | Positively charged non-natural amino acids, methods of making and using thereof in peptides |
| GB9711990D0 (en) | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| IL141868A0 (en) | 1998-10-05 | 2002-03-10 | M & E Biotech As | Novel methods for therapeutic vaccination |
| NO311807B1 (no) | 1999-03-04 | 2002-01-28 | Bionor Immuno As | HIV-peptider, antigener, vaksinepreparater, immunoassay- testsett og en metode for påvisning av antistoffer fremkalt av HIV |
| EP1200109A4 (en) | 1999-07-19 | 2005-06-15 | Epimmune Inc | USE OF PEPTIDE NUCLEIC ACID COMPOUNDS TO TRIGGER CELLULAR IMMUNE RESPONSES TO HEPATITIS C |
| US20020076415A1 (en) | 1999-12-14 | 2002-06-20 | Jing-Hsiung Ou | Hepatitis C virus gene products |
| GB0005703D0 (en) | 2000-03-09 | 2000-05-03 | Alpharma As | Compounds |
| AU2000273396A1 (en) | 2000-09-01 | 2002-03-22 | Epimmune, Inc. | Hla binding peptides and their uses |
| NO314588B1 (no) * | 2000-09-04 | 2003-04-14 | Bionor Immuno As | HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV |
| NO314587B1 (no) | 2000-09-04 | 2003-04-14 | Bionor Immuno As | HIV regulatoriske- og hjelpepeptider, antigener, vaksinepreparater, immunoassay testsett og en metode for påvisning av antistoffer fremkaltav HIV |
| EP1195381A1 (de) | 2000-09-28 | 2002-04-10 | Immusystems GmbH | CD4+ T-Lymphozyten spezifische Hepatitis C Virus-Epitope |
| GB0026094D0 (en) | 2000-10-25 | 2000-12-13 | Imp College Innovations Ltd | Methods |
| ATE356385T1 (de) | 2002-06-10 | 2007-03-15 | Algonomics N V | Verfahren zur vorhersage der bindungsaffinität der mhc-peptid-komplexe |
| EP2301972A1 (en) * | 2002-08-12 | 2011-03-30 | The Council Of The Queensland Institute Of Medical Research | Method to prepare immunogenic lipopeptides comprising T-helper and B-cell epitopes |
| EP2402026A3 (en) | 2002-09-13 | 2012-04-18 | Intercell AG | Method for isolating hepatitis C virus peptides |
| KR20120064120A (ko) | 2004-06-01 | 2012-06-18 | 제넨테크, 인크. | 항체 약물 접합체 및 방법 |
| EP1652858A1 (en) | 2004-10-28 | 2006-05-03 | Innogenetics N.V. | Peptides for inducing a CTL and/or HTL response to hepatitis C virus |
| EP1817341A2 (en) | 2004-11-29 | 2007-08-15 | Seattle Genetics, Inc. | Engineered antibodies and immunoconjugates |
| US8252893B2 (en) | 2005-01-31 | 2012-08-28 | Board Of Trustees Of The University Of Arkansas | CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof |
| WO2008107400A1 (en) | 2007-03-02 | 2008-09-12 | Genimmune N.V. | Hcv polyepitope construct and uses thereof |
| CA2767063A1 (en) * | 2009-07-03 | 2011-01-06 | Bionor Immuno As | Novel therapeutic and diagnostic means |
| US9550811B2 (en) | 2010-12-02 | 2017-01-24 | Bionor Immuno As | Peptide scaffold design |
| US9493514B2 (en) * | 2011-01-06 | 2016-11-15 | Bionor Immuno As | Dimeric scaffold proteins comprising HIV-1 GP120 and GP41 epitopes |
| US8618303B2 (en) * | 2011-01-07 | 2013-12-31 | Hoffmann-La Roche Inc. | Pyrrolidine derivatives |
-
2013
- 2013-06-06 JP JP2015515530A patent/JP6310909B2/ja not_active Expired - Fee Related
- 2013-06-06 EA EA201492262A patent/EA201492262A1/ru unknown
- 2013-06-06 AU AU2013273482A patent/AU2013273482A1/en not_active Abandoned
- 2013-06-06 CA CA2874923A patent/CA2874923C/en active Active
- 2013-06-06 KR KR20157000273A patent/KR20150018870A/ko not_active Withdrawn
- 2013-06-06 CN CN201380039292.3A patent/CN104619718A/zh active Pending
- 2013-06-06 IN IN2769KON2014 patent/IN2014KN02769A/en unknown
- 2013-06-06 NZ NZ702146A patent/NZ702146A/en not_active IP Right Cessation
- 2013-06-06 MX MX2014014683A patent/MX2014014683A/es unknown
- 2013-06-06 HK HK15108544.7A patent/HK1207871A1/xx unknown
- 2013-06-06 WO PCT/EP2013/061751 patent/WO2013182661A1/en not_active Ceased
- 2013-06-06 EP EP13727202.7A patent/EP2859011B1/en active Active
- 2013-06-06 US US14/406,016 patent/US10501499B2/en active Active
- 2013-06-06 BR BR112014030466A patent/BR112014030466A2/pt not_active IP Right Cessation
-
2014
- 2014-11-25 IL IL235891A patent/IL235891A0/en unknown
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