JP2015520241A5 - - Google Patents

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Publication number
JP2015520241A5
JP2015520241A5 JP2015518599A JP2015518599A JP2015520241A5 JP 2015520241 A5 JP2015520241 A5 JP 2015520241A5 JP 2015518599 A JP2015518599 A JP 2015518599A JP 2015518599 A JP2015518599 A JP 2015518599A JP 2015520241 A5 JP2015520241 A5 JP 2015520241A5
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JP
Japan
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composition
indirubin
surface stabilizer
average particle
effective average
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JP2015518599A
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English (en)
Japanese (ja)
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JP6382187B2 (ja
JP2015520241A (ja
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Priority claimed from PCT/US2013/046981 external-priority patent/WO2013192493A1/en
Publication of JP2015520241A publication Critical patent/JP2015520241A/ja
Publication of JP2015520241A5 publication Critical patent/JP2015520241A5/ja
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Publication of JP6382187B2 publication Critical patent/JP6382187B2/ja
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JP2015518599A 2012-06-21 2013-06-21 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法 Active JP6382187B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261662469P 2012-06-21 2012-06-21
US61/662,469 2012-06-21
PCT/US2013/046981 WO2013192493A1 (en) 2012-06-21 2013-06-21 Nanoparticles of indirubin, derivatives thereof and methods of making and using same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018144837A Division JP2018199685A (ja) 2012-06-21 2018-08-01 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法

Publications (3)

Publication Number Publication Date
JP2015520241A JP2015520241A (ja) 2015-07-16
JP2015520241A5 true JP2015520241A5 (https=) 2016-08-12
JP6382187B2 JP6382187B2 (ja) 2018-08-29

Family

ID=49769412

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2015518599A Active JP6382187B2 (ja) 2012-06-21 2013-06-21 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法
JP2018144837A Pending JP2018199685A (ja) 2012-06-21 2018-08-01 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法
JP2020001832A Pending JP2020073564A (ja) 2012-06-21 2020-01-09 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法
JP2021118361A Pending JP2021181447A (ja) 2012-06-21 2021-07-19 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法
JP2023021518A Pending JP2023062070A (ja) 2012-06-21 2023-02-15 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2018144837A Pending JP2018199685A (ja) 2012-06-21 2018-08-01 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法
JP2020001832A Pending JP2020073564A (ja) 2012-06-21 2020-01-09 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法
JP2021118361A Pending JP2021181447A (ja) 2012-06-21 2021-07-19 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法
JP2023021518A Pending JP2023062070A (ja) 2012-06-21 2023-02-15 インジルビンのナノ微粒子、その誘導体およびそれらを作製しかつ利用する方法

Country Status (6)

Country Link
US (3) US10039829B2 (https=)
EP (2) EP2863897B1 (https=)
JP (5) JP6382187B2 (https=)
CN (2) CN110123763A (https=)
CA (1) CA2914782C (https=)
WO (1) WO2013192493A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2863897B1 (en) * 2012-06-21 2019-06-19 Phosphorex Inc. Nanoparticles of indirubin, derivatives thereof and methods of making and using same
JP2017500343A (ja) * 2013-12-20 2017-01-05 フォスフォレックス，インコーポレーテッド インジルビン固体分散体組成物
RU2630561C2 (ru) * 2015-10-20 2017-09-11 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России Способ получения водно-солевых дисперсий фуллерена
EP3600259A4 (en) * 2017-03-29 2020-11-25 Phosphorex, Inc. NEW PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBINE AND DERIVATIVES THEREOF AND METHODS FOR THE MANUFACTURE AND USE OF THEM
RU2721318C1 (ru) * 2019-02-28 2020-05-18 Автономная некоммерческая образовательная организация высшего образования "Сколковский институт науки и технологий" Способ получения золей и суспензий
US20200345645A1 (en) * 2019-05-03 2020-11-05 Azora Therapeutics, Inc. Compositions comprising indigo and/or an indigo derivative and methods of use thereof
CN114668744A (zh) * 2022-03-23 2022-06-28 成都大学 一种靛玉红固体脂质纳米粒及其制备方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929242A (en) * 1986-11-26 1990-05-29 Baxter International Inc. Solution and method for maintaining patency of a catheter
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
TW384224B (en) * 1994-05-25 2000-03-11 Nano Sys Llc Method of preparing submicron particles of a therapeutic or diagnostic agent
US7998507B2 (en) * 2000-09-21 2011-08-16 Elan Pharma International Ltd. Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors
DE10129028A1 (de) * 2001-06-11 2003-01-02 Schering Ag Lösliche Cdk-inhibitorische Indirubinderivate
US20050154046A1 (en) * 2004-01-12 2005-07-14 Longgui Wang Methods of treating an inflammatory-related disease
CA2469649C (en) * 2001-12-13 2011-05-03 Natrogen Therapeutics, Inc. Derivatives of isoindigo, indigo and indirubin and use in treating cancer
WO2003080027A1 (en) * 2002-03-20 2003-10-02 Elan Pharma International, Ltd. Nanoparticulate compositions of angiogenesis inhibitors
US20080220074A1 (en) * 2002-10-04 2008-09-11 Elan Corporation Plc Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same
JP2006520392A (ja) * 2003-03-13 2006-09-07 コントロールド・ケミカルズ・インコーポレーテッド 薬物の乱用可能性を低下させ且つ作用持続時間を延長する化合物および方法
CN1615852A (zh) * 2003-11-10 2005-05-18 许军 靛玉红口服滴丸及制备工艺
KR100588803B1 (ko) * 2004-01-27 2006-06-12 학교법인조선대학교 암세포주에 항암활성을 지닌 인디루빈 유도체
UA89513C2 (uk) * 2004-12-03 2010-02-10 Элан Фарма Интернешнл Лтд. Стабільна композиція з наночастинок ралоксифену гідрохлориду
CA2590675A1 (en) * 2004-12-15 2006-06-22 Elan Pharma International Ltd. Nanoparticulate tacrolimus formulations
WO2006069098A1 (en) * 2004-12-22 2006-06-29 Elan Pharma International Ltd. Nanoparticulate bicalutamide formulations
EP1835890A2 (en) * 2005-01-06 2007-09-26 Elan Pharma International Limited Nanoparticulate candesartan formulations
JP2008531591A (ja) * 2005-02-24 2008-08-14 エラン・ファルマ・インターナショナル・リミテッド ドセタキセルおよびそれらの類似体のナノ粒子製剤
WO2006099121A2 (en) * 2005-03-10 2006-09-21 Elan Pharma International Limited Formulations of a nanoparticulate finasteride, dutasteride and tamsulosin hydrochloride, and mixtures thereof
BRPI0606280A2 (pt) * 2005-03-17 2009-06-09 Elan Pharma Int Ltd composições de bisfosfonato nanoparticulado
WO2006102494A2 (en) * 2005-03-23 2006-09-28 Elan Pharma International Limited Nanoparticulate corticosteroid and antihistamine formulations
AU2006235478B2 (en) * 2005-04-12 2011-07-21 Elan Pharma International Limited Nanoparticulate and controlled release compositions comprising cyclosporine
AU2006235487B2 (en) * 2005-04-12 2011-12-22 Elan Pharma International Limited Nanoparticulate quinazoline derivative formulations
JP2008545752A (ja) * 2005-06-02 2008-12-18 テルシカ インコーポレーティッド 成長障害を処置するための方法
CN101023944A (zh) * 2006-02-23 2007-08-29 黎明涛 靛玉红衍生物在制备治疗神经退行性变疾病药物中的应用
CN101074229B (zh) 2007-06-08 2010-09-01 无锡杰西医药科技有限公司 7-氮杂靛玉红和7-氮杂异靛蓝衍生物制备及其药学用途
EP2057982A1 (en) 2007-11-09 2009-05-13 Archimedes Development Limited Intranasal compositions
WO2009117042A1 (en) * 2008-03-21 2009-09-24 Adlyfe, Inc. Use of pyrene to carry non-peptide agents across the blood brain barrier
EP2113253B1 (en) 2008-04-30 2010-03-31 Immatics Biotechnologies GmbH Novel formulations of tumour-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules for vaccines
CN101362066B (zh) * 2008-09-27 2010-12-22 同济大学 脂质体包埋量子点的二氧化硅微球的制备方法及其产品
CN101775082B (zh) * 2010-02-09 2012-06-27 中国药科大学 基于两性离子的电荷反转型壳聚糖衍生物及其在药剂中的应用
CN102018736B (zh) * 2010-11-19 2012-03-28 成都中医药大学 一种青黛饮片及其制备方法
CN102228433B (zh) * 2011-06-29 2012-11-28 上海中医药大学 过饱和自微乳制剂及其制备方法和应用
EP2863897B1 (en) * 2012-06-21 2019-06-19 Phosphorex Inc. Nanoparticles of indirubin, derivatives thereof and methods of making and using same

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