JP2015519322A5 - - Google Patents
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- Publication number
- JP2015519322A5 JP2015519322A5 JP2015509395A JP2015509395A JP2015519322A5 JP 2015519322 A5 JP2015519322 A5 JP 2015519322A5 JP 2015509395 A JP2015509395 A JP 2015509395A JP 2015509395 A JP2015509395 A JP 2015509395A JP 2015519322 A5 JP2015519322 A5 JP 2015519322A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- groups
- cycloalkyl
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WDWLZCFTSWFXCZ-UHFFFAOYSA-N CC(C=CC1=C2CCC1Oc1ccc(C(CC(O)=O)CO3)c3c1)(C=C2I)N Chemical compound CC(C=CC1=C2CCC1Oc1ccc(C(CC(O)=O)CO3)c3c1)(C=C2I)N WDWLZCFTSWFXCZ-UHFFFAOYSA-N 0.000 description 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Cc1ccccc1 Chemical compound Cc1ccccc1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 1
- BSKHPKMHTQYZBB-UHFFFAOYSA-N Cc1ccccn1 Chemical compound Cc1ccccn1 BSKHPKMHTQYZBB-UHFFFAOYSA-N 0.000 description 1
- MXDRPNGTQDRKQM-UHFFFAOYSA-N Cc1cccnn1 Chemical compound Cc1cccnn1 MXDRPNGTQDRKQM-UHFFFAOYSA-N 0.000 description 1
- FKNQCJSGGFJEIZ-UHFFFAOYSA-N Cc1ccncc1 Chemical compound Cc1ccncc1 FKNQCJSGGFJEIZ-UHFFFAOYSA-N 0.000 description 1
- LVILGAOSPDLNRM-UHFFFAOYSA-N Cc1ccncn1 Chemical compound Cc1ccncn1 LVILGAOSPDLNRM-UHFFFAOYSA-N 0.000 description 1
- ITQTTZVARXURQS-UHFFFAOYSA-N Cc1cnccc1 Chemical compound Cc1cnccc1 ITQTTZVARXURQS-UHFFFAOYSA-N 0.000 description 1
- CAWHJQAVHZEVTJ-UHFFFAOYSA-N Cc1cnccn1 Chemical compound Cc1cnccn1 CAWHJQAVHZEVTJ-UHFFFAOYSA-N 0.000 description 1
- TWGNOYAGHYUFFR-UHFFFAOYSA-N Cc1cncnc1 Chemical compound Cc1cncnc1 TWGNOYAGHYUFFR-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12166095 | 2012-04-30 | ||
| EP12166095.5 | 2012-04-30 | ||
| PCT/EP2013/058840 WO2013164292A1 (en) | 2012-04-30 | 2013-04-29 | Indanyloxydihydrobenzofuranylacetic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015519322A JP2015519322A (ja) | 2015-07-09 |
| JP2015519322A5 true JP2015519322A5 (enExample) | 2016-06-23 |
| JP6236702B2 JP6236702B2 (ja) | 2017-11-29 |
Family
ID=48325664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015509395A Active JP6236702B2 (ja) | 2012-04-30 | 2013-04-29 | インダニルオキシジヒドロベンゾフラニル酢酸 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8809376B2 (enExample) |
| EP (1) | EP2844653B1 (enExample) |
| JP (1) | JP6236702B2 (enExample) |
| AR (1) | AR090879A1 (enExample) |
| TW (1) | TW201406739A (enExample) |
| UY (1) | UY34773A (enExample) |
| WO (1) | WO2013164292A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014122067A1 (en) * | 2013-02-06 | 2014-08-14 | Boehringer Ingelheim International Gmbh | New indanyloxydihydrobenzofuranylacetic acids |
| EP3068788A1 (en) | 2013-11-14 | 2016-09-21 | Cadila Healthcare Limited | Novel heterocyclic compounds |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| KR102708681B1 (ko) | 2018-02-13 | 2024-09-26 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| EP4600247A3 (en) | 2018-04-19 | 2025-11-19 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| UA126421C2 (uk) | 2018-07-13 | 2022-09-28 | Гіліад Сайєнсіз, Інк. | Інгібітори pd-1/pd-l1 |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| CN110372651A (zh) * | 2019-07-22 | 2019-10-25 | 上海师范大学 | 一种含苯并呋喃骨架的茚衍生物的合成方法 |
| BR112022006546A2 (pt) | 2019-10-07 | 2022-08-30 | Kallyope Inc | Agonistas de gpr119 |
| CA3173731A1 (en) | 2020-02-28 | 2021-09-02 | Kallyope, Inc. | Gpr40 agonists |
| CN116323608A (zh) | 2020-05-19 | 2023-06-23 | 卡尔优普公司 | Ampk活化剂 |
| EP4172162A4 (en) | 2020-06-26 | 2024-08-07 | Kallyope, Inc. | AMPK ACTIVATORS |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4594611B2 (ja) * | 2002-11-08 | 2010-12-08 | 武田薬品工業株式会社 | 受容体機能調節剤 |
| EP1559422B1 (en) | 2002-11-08 | 2014-04-30 | Takeda Pharmaceutical Company Limited | Receptor function controlling agent |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| EP1630152A4 (en) | 2003-05-30 | 2009-09-23 | Takeda Pharmaceutical | CONDENSED CYCLIC COMPOUND |
| JP4805552B2 (ja) * | 2003-05-30 | 2011-11-02 | 武田薬品工業株式会社 | 縮合環化合物 |
| EP1924546A1 (en) | 2005-09-14 | 2008-05-28 | Amgen, Inc | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| KR20080103584A (ko) | 2006-03-30 | 2008-11-27 | 아사히 가세이 파마 가부시키가이샤 | 치환 이환식 환상 유도체 및 그 용도 |
| CL2007001873A1 (es) | 2006-06-27 | 2008-01-04 | Takeda Pharmaceutical | Acido((3s))-6-((¨2,6-dimetil-4-(3-(metilsulfonil)-propoxi)bifenil-3-il)metoxi-2,3-dihidro-1-benzofuran-3-il)acetico o una sal del mismo |
| CA2727340A1 (en) | 2008-06-25 | 2009-12-30 | Daiichi Sankyo Company, Limited | Carboxylic acid compound |
| US8748462B2 (en) | 2008-10-15 | 2014-06-10 | Amgen Inc. | Spirocyclic GPR40 modulators |
| WO2010143733A1 (en) | 2009-06-09 | 2010-12-16 | Takeda Pharmaceutical Company Limited | Novel fused cyclic compound and use thereof |
| TW201643169A (zh) | 2010-07-09 | 2016-12-16 | 艾伯維股份有限公司 | 作為s1p調節劑的螺-哌啶衍生物 |
| EP2646425B1 (en) | 2010-12-01 | 2015-06-10 | Boehringer Ingelheim International Gmbh | Indanyloxydihydrobenzofuranylacetic acids useful for the treatment of metabolic syndrome |
-
2013
- 2013-04-24 US US13/869,144 patent/US8809376B2/en active Active
- 2013-04-29 JP JP2015509395A patent/JP6236702B2/ja active Active
- 2013-04-29 AR ARP130101452A patent/AR090879A1/es unknown
- 2013-04-29 TW TW102115310A patent/TW201406739A/zh unknown
- 2013-04-29 WO PCT/EP2013/058840 patent/WO2013164292A1/en not_active Ceased
- 2013-04-29 EP EP13720889.8A patent/EP2844653B1/en not_active Not-in-force
- 2013-04-30 UY UY0001034773A patent/UY34773A/es unknown
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