JP2015517801A5 - - Google Patents
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- JP2015517801A5 JP2015517801A5 JP2014561056A JP2014561056A JP2015517801A5 JP 2015517801 A5 JP2015517801 A5 JP 2015517801A5 JP 2014561056 A JP2014561056 A JP 2014561056A JP 2014561056 A JP2014561056 A JP 2014561056A JP 2015517801 A5 JP2015517801 A5 JP 2015517801A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- markers
- pervasive developmental
- developmental disorder
- expression level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 208000029560 autism spectrum disease Diseases 0.000 claims description 85
- 208000012202 Pervasive developmental disease Diseases 0.000 claims description 83
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- 239000003550 marker Substances 0.000 claims description 26
- 208000024891 symptom Diseases 0.000 claims description 22
- 238000011282 treatment Methods 0.000 claims description 21
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- 238000012360 testing method Methods 0.000 claims description 15
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- 239000003153 chemical reaction reagent Substances 0.000 claims description 13
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- 206010050337 Cerumen impaction Diseases 0.000 claims description 2
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- 210000003608 fece Anatomy 0.000 claims description 2
- 210000004211 gastric acid Anatomy 0.000 claims description 2
- 210000004251 human milk Anatomy 0.000 claims description 2
- 235000020256 human milk Nutrition 0.000 claims description 2
- 230000000951 immunodiffusion Effects 0.000 claims description 2
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- 210000002751 lymph Anatomy 0.000 claims description 2
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- 108020004999 messenger RNA Proteins 0.000 claims description 2
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- 210000003097 mucus Anatomy 0.000 claims description 2
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- 210000004912 pericardial fluid Anatomy 0.000 claims description 2
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- 210000004910 pleural fluid Anatomy 0.000 claims description 2
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- 238000011002 quantification Methods 0.000 claims description 2
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- 230000002829 reductive effect Effects 0.000 claims description 2
- 238000012340 reverse transcriptase PCR Methods 0.000 claims description 2
- 210000003296 saliva Anatomy 0.000 claims description 2
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- 210000000582 semen Anatomy 0.000 claims description 2
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- 210000002700 urine Anatomy 0.000 claims description 2
- 206010046901 vaginal discharge Diseases 0.000 claims description 2
- 210000004127 vitreous body Anatomy 0.000 claims description 2
- 238000001262 western blot Methods 0.000 claims description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- -1 hnRNA Proteins 0.000 claims 1
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 208000012239 Developmental disease Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
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- 238000002875 fluorescence polarization Methods 0.000 description 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261606935P | 2012-03-05 | 2012-03-05 | |
| US61/606,935 | 2012-03-05 | ||
| PCT/US2013/029201 WO2013134315A1 (en) | 2012-03-05 | 2013-03-05 | Compositions and methods for diagnosis and treatment of pervasive developmental disorder |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018072819A Division JP2018153184A (ja) | 2012-03-05 | 2018-04-05 | 広汎性発達障害の診断および治療のための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015517801A JP2015517801A (ja) | 2015-06-25 |
| JP2015517801A5 true JP2015517801A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2016-04-21 |
Family
ID=49117277
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014561056A Pending JP2015517801A (ja) | 2012-03-05 | 2013-03-05 | 広汎性発達障害の診断および治療のための組成物および方法 |
| JP2018072819A Pending JP2018153184A (ja) | 2012-03-05 | 2018-04-05 | 広汎性発達障害の診断および治療のための組成物および方法 |
| JP2020137031A Pending JP2020193986A (ja) | 2012-03-05 | 2020-08-14 | 広汎性発達障害の診断および治療のための組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018072819A Pending JP2018153184A (ja) | 2012-03-05 | 2018-04-05 | 広汎性発達障害の診断および治療のための組成物および方法 |
| JP2020137031A Pending JP2020193986A (ja) | 2012-03-05 | 2020-08-14 | 広汎性発達障害の診断および治療のための組成物および方法 |
Country Status (9)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012376214B2 (en) | 2012-04-02 | 2019-02-14 | Berg Llc | Interrogatory cell-based assays and uses thereof |
| US9176113B1 (en) * | 2014-04-11 | 2015-11-03 | Synapdx Corporation | Methods and systems for determining autism spectrum disorder risk |
| US20150294081A1 (en) | 2014-04-11 | 2015-10-15 | Synapdx Corporation | Methods and systems for determining autism spectrum disorder risk |
| WO2015191783A2 (en) | 2014-06-10 | 2015-12-17 | Abbvie Inc. | Biomarkers for inflammatory disease and methods of using same |
| AU2015314956A1 (en) | 2014-09-11 | 2017-04-06 | Berg Llc | Bayesian causal relationship network models for healthcare diagnosis and treatment based on patient data |
| HUE058209T2 (hu) * | 2015-05-22 | 2022-07-28 | Univ Arizona State | Módszerek az autizmus spektrum zavar és azzal összefüggõ tünetek kezelésére |
| US11328951B2 (en) | 2016-04-01 | 2022-05-10 | Intel Corporation | Transistor cells including a deep via lined wit h a dielectric material |
| US10650621B1 (en) | 2016-09-13 | 2020-05-12 | Iocurrents, Inc. | Interfacing with a vehicular controller area network |
| CN106885858A (zh) * | 2017-03-10 | 2017-06-23 | 方雷 | 一种高效的痕量临床病人样本的高通量全蛋白组学定量分析方法 |
| CN107312846A (zh) * | 2017-07-12 | 2017-11-03 | 北京赛尔维康生物医学科技有限公司 | Capg和ptgis基因在制备脊柱侧弯检测试剂盒中的应用 |
| CN109212226B (zh) * | 2018-09-06 | 2021-04-06 | 中国人民解放军联勤保障部队第九〇四医院 | 预测急性高山病发病风险的血浆蛋白标志物及其在制备诊断ams易感性试剂盒中的应用 |
| CN109239334A (zh) * | 2018-09-10 | 2019-01-18 | 吉林大学 | 建立时间分辨荧光免疫层析法检测MxA试剂盒 |
| WO2020180424A1 (en) | 2019-03-04 | 2020-09-10 | Iocurrents, Inc. | Data compression and communication using machine learning |
| WO2020215043A1 (en) * | 2019-04-19 | 2020-10-22 | Yale University | Advanced glycation end-product breaking biocatalysts |
| KR102158009B1 (ko) * | 2019-06-13 | 2020-09-21 | 고려대학교 산학협력단 | 주의력 결핍/과잉행동장애 진단용 마커로서의 14-3-3γ의 용도 |
| CN112442527B (zh) * | 2019-08-27 | 2022-11-11 | 深圳市英马诺生物科技有限公司 | 孤独症诊断试剂盒、基因芯片、基因靶点筛选方法及应用 |
| EP4348265A2 (en) * | 2021-05-25 | 2024-04-10 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Diagnosis of autism spectrum disorder by multiomics platform |
| TWI866002B (zh) * | 2021-12-29 | 2024-12-11 | 財團法人生物技術開發中心 | 反義寡核苷酸及其用途 |
| ES2976116A1 (es) * | 2023-12-15 | 2024-07-23 | Chrmtx Sl | Biomarcadores nucleares de la enfermedad de Alzheimer (EA), sus usos y métodos |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4659025B2 (ja) * | 2004-04-15 | 2011-03-30 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 神経系傷害および他の神経障害についての生物マーカーとしての神経タンパク質 |
| GB0419124D0 (en) * | 2004-08-27 | 2004-09-29 | Proteome Sciences Plc | Methods and compositions relating to Alzheimer's disease |
| AU2006206159A1 (en) * | 2005-01-24 | 2006-07-27 | Massachusetts Institute Of Technology | Method for modeling cell signaling systems by means of bayesian networks |
| EP1840574A1 (en) * | 2006-03-30 | 2007-10-03 | Institut Pasteur | Use of the alpha chain of brain spectrin and fragments thereof, for diagnosing cerebral diseases |
| US20090117562A1 (en) * | 2007-04-09 | 2009-05-07 | Valerie Wailin Hu | Method and kit for diagnosing Autism using gene expression profiling |
| CA2716375C (en) * | 2008-02-20 | 2018-05-29 | The Children's Hospital Of Philadelphia | Genetic alterations associated with autism and the autistic phenotype and methods of use thereof for the diagnosis and treatmemt of autism |
| US8173369B2 (en) * | 2008-05-15 | 2012-05-08 | The Regents Of The University Of California | Peripheral gene expression biomarkers for autism |
| US20110294693A1 (en) * | 2008-11-17 | 2011-12-01 | The George Washington University | Compositions and Methods for Identifying Autism Spectrum Disorders |
| US20120178637A1 (en) * | 2009-07-07 | 2012-07-12 | Abbott Laboratories | Biomarkers and methods for detecting alzheimer's disease |
| US20110059861A1 (en) * | 2009-09-08 | 2011-03-10 | Nodality, Inc. | Analysis of cell networks |
| US20130123124A1 (en) * | 2010-03-12 | 2013-05-16 | Children's Medical Center Corporation | Methods and compositions for characterizing autism spectrum disorder based on gene expression patterns |
| EA201391245A1 (ru) * | 2011-03-02 | 2014-05-30 | Берг Ллк | Интеррогативные клеточные анализы и их применение |
| CA2874432A1 (en) * | 2012-05-22 | 2013-11-28 | Berg Llc | Interrogatory cell-based assays for indentifying drug-induced toxicity markers |
-
2013
- 2013-03-05 EP EP13758001.5A patent/EP2823063A4/en not_active Withdrawn
- 2013-03-05 JP JP2014561056A patent/JP2015517801A/ja active Pending
- 2013-03-05 CA CA2866407A patent/CA2866407A1/en not_active Abandoned
- 2013-03-05 AU AU2013230045A patent/AU2013230045A1/en not_active Abandoned
- 2013-03-05 WO PCT/US2013/029201 patent/WO2013134315A1/en active Application Filing
- 2013-03-05 KR KR20147028035A patent/KR20140140069A/ko not_active Withdrawn
- 2013-03-05 US US14/383,450 patent/US20150023949A1/en not_active Abandoned
- 2013-03-05 HK HK15106693.0A patent/HK1206393A1/xx unknown
- 2013-03-05 CN CN201380022420.3A patent/CN104364393A/zh active Pending
-
2017
- 2017-12-04 US US15/830,982 patent/US20180275146A1/en not_active Abandoned
-
2018
- 2018-04-05 JP JP2018072819A patent/JP2018153184A/ja active Pending
-
2019
- 2019-02-14 US US16/275,944 patent/US20190242909A1/en not_active Abandoned
-
2020
- 2020-08-14 JP JP2020137031A patent/JP2020193986A/ja active Pending
-
2021
- 2021-06-11 US US17/346,152 patent/US20220137070A1/en not_active Abandoned
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