JP2015508099A5 - - Google Patents
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- JP2015508099A5 JP2015508099A5 JP2014558733A JP2014558733A JP2015508099A5 JP 2015508099 A5 JP2015508099 A5 JP 2015508099A5 JP 2014558733 A JP2014558733 A JP 2014558733A JP 2014558733 A JP2014558733 A JP 2014558733A JP 2015508099 A5 JP2015508099 A5 JP 2015508099A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- pharmaceutically acceptable
- conr
- conditions
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261601101P | 2012-02-21 | 2012-02-21 | |
| US61/601,101 | 2012-02-21 | ||
| PCT/US2012/070252 WO2013126132A1 (en) | 2012-02-21 | 2012-12-18 | Cyclic diaminopyrimidine derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015508099A JP2015508099A (ja) | 2015-03-16 |
| JP2015508099A5 true JP2015508099A5 (https=) | 2016-12-08 |
| JP6059260B2 JP6059260B2 (ja) | 2017-01-11 |
Family
ID=47459190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014558733A Expired - Fee Related JP6059260B2 (ja) | 2012-02-21 | 2012-12-18 | 環状ジアミノピリジン誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9073944B2 (https=) |
| EP (1) | EP2817306B1 (https=) |
| JP (1) | JP6059260B2 (https=) |
| CN (1) | CN104254531B (https=) |
| AR (1) | AR090103A1 (https=) |
| AU (1) | AU2012370450B2 (https=) |
| CA (1) | CA2865040C (https=) |
| ES (1) | ES2552518T3 (https=) |
| IL (1) | IL233986A (https=) |
| WO (1) | WO2013126132A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2955612C (en) | 2014-07-18 | 2022-05-17 | Advaxis, Inc. | Combination of a pd-1 antagonist and a listeria-based vaccine for treating prostate cancer |
| CN114989205A (zh) | 2016-12-22 | 2022-09-02 | 卡里塞拉生物科学股份公司 | 用于抑制精氨酸酶活性的组合物和方法 |
| EA202192575A1 (ru) | 2019-03-21 | 2022-01-14 | Онксео | Соединения dbait в сочетании с ингибиторами киназ для лечения рака |
| CN114761006A (zh) | 2019-11-08 | 2022-07-15 | Inserm(法国国家健康医学研究院) | 对激酶抑制剂产生耐药性的癌症的治疗方法 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| KR20220153582A (ko) | 2020-02-14 | 2022-11-18 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 마크로시클릭 ulk1/2 억제제 |
| EP4225281A1 (en) * | 2020-10-05 | 2023-08-16 | Merck Patent GmbH | Lmp7-selective inhibitors for the treatment of blood disorders and solid tumors |
| JP7556310B2 (ja) * | 2021-02-26 | 2024-09-26 | スズキ株式会社 | 電動車両 |
| CA3212583A1 (en) | 2021-03-27 | 2022-10-06 | Daniel Gooding | Compositions having improved bioavailability of therapeutics |
| US20250000859A1 (en) | 2021-08-25 | 2025-01-02 | Alesta Therapeutics BV | Use of gcn2 inhibitors in treating cancer |
| EP4493151A2 (en) * | 2022-03-14 | 2025-01-22 | TRX Biosciences Limited | Compositions having improved bioavailability of therapeutics and uses thereof |
| TW202404979A (zh) * | 2022-07-18 | 2024-02-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抑制並誘導ｅｇｆｒ降解的大環類化合物、其製備方法及其在醫藥上的應用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| DE69720965T2 (de) | 1996-02-13 | 2004-02-05 | Astrazeneca Ab | Chinazolinderivate und deren verwendung als vegf hemmer |
| NZ331191A (en) | 1996-03-05 | 2000-03-27 | Zeneca Ltd | 4-anilinoquinazoline derivatives and pharmaceutical compositions thereof |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| MXPA02012903A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como inhibidores de angiogenesis. |
| MXPA02012905A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como agentes de dano vascular.. |
| CN1863780A (zh) * | 2002-08-14 | 2006-11-15 | 沃泰克斯药物股份有限公司 | 蛋白激酶抑制剂及其应用 |
| WO2005011597A2 (en) * | 2003-07-29 | 2005-02-10 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| WO2005012294A1 (en) * | 2003-07-30 | 2005-02-10 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases |
| GB0321710D0 (en) * | 2003-09-16 | 2003-10-15 | Novartis Ag | Organic compounds |
| CA2631875A1 (en) * | 2005-12-06 | 2007-10-04 | Rigel Pharmaceuticals, Inc. | Formulation of insoluble small molecule therapeutics in lipid-based carriers |
| US7659280B2 (en) * | 2006-02-17 | 2010-02-09 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds for treating or preventing autoimmune diseases |
| ATE540041T1 (de) * | 2006-11-21 | 2012-01-15 | Rigel Pharmaceuticals Inc | Prodrug-salze von 2,4-pyrimidindiaminverbindungen und anwendungen davon |
| KR20110073500A (ko) | 2008-09-08 | 2011-06-29 | 메르크 파텐트 게엠베하 | 오로라 키나아제 억제제로서 마크로사이클릭 피리미딘 |
-
2012
- 2012-12-18 US US14/379,625 patent/US9073944B2/en active Active
- 2012-12-18 CA CA2865040A patent/CA2865040C/en active Active
- 2012-12-18 EP EP12808646.9A patent/EP2817306B1/en active Active
- 2012-12-18 WO PCT/US2012/070252 patent/WO2013126132A1/en not_active Ceased
- 2012-12-18 AU AU2012370450A patent/AU2012370450B2/en not_active Ceased
- 2012-12-18 JP JP2014558733A patent/JP6059260B2/ja not_active Expired - Fee Related
- 2012-12-18 CN CN201280070330.7A patent/CN104254531B/zh not_active Expired - Fee Related
- 2012-12-18 ES ES12808646.9T patent/ES2552518T3/es active Active
-
2013
- 2013-02-21 AR ARP130100516 patent/AR090103A1/es unknown
-
2014
- 2014-08-06 IL IL233986A patent/IL233986A/en active IP Right Grant
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