JP2015506347A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015506347A5 JP2015506347A5 JP2014548899A JP2014548899A JP2015506347A5 JP 2015506347 A5 JP2015506347 A5 JP 2015506347A5 JP 2014548899 A JP2014548899 A JP 2014548899A JP 2014548899 A JP2014548899 A JP 2014548899A JP 2015506347 A5 JP2015506347 A5 JP 2015506347A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- nitrogen
- membered
- oxygen
- sulfur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 Cc1cc(OC*)ccc1 Chemical compound Cc1cc(OC*)ccc1 0.000 description 4
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579711P | 2011-12-23 | 2011-12-23 | |
| US61/579,711 | 2011-12-23 | ||
| US201261672030P | 2012-07-16 | 2012-07-16 | |
| US61/672,030 | 2012-07-16 | ||
| US201261716172P | 2012-10-19 | 2012-10-19 | |
| US61/716,172 | 2012-10-19 | ||
| PCT/US2012/070980 WO2013096637A1 (en) | 2011-12-23 | 2012-12-20 | Heteroaryls and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015506347A JP2015506347A (ja) | 2015-03-02 |
| JP2015506347A5 true JP2015506347A5 (OSRAM) | 2016-02-18 |
Family
ID=48655164
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548902A Pending JP2015503505A (ja) | 2011-12-23 | 2012-12-20 | ヘテロアリールおよびその使用 |
| JP2014548896A Pending JP2015503504A (ja) | 2011-12-23 | 2012-12-20 | ヘテロアリールおよびその使用 |
| JP2014548899A Pending JP2015506347A (ja) | 2011-12-23 | 2012-12-20 | ヘテロアリールおよびその使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548902A Pending JP2015503505A (ja) | 2011-12-23 | 2012-12-20 | ヘテロアリールおよびその使用 |
| JP2014548896A Pending JP2015503504A (ja) | 2011-12-23 | 2012-12-20 | ヘテロアリールおよびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20130165472A1 (OSRAM) |
| EP (3) | EP2793879A4 (OSRAM) |
| JP (3) | JP2015503505A (OSRAM) |
| AR (3) | AR089446A1 (OSRAM) |
| TW (3) | TW201331194A (OSRAM) |
| UY (3) | UY34539A (OSRAM) |
| WO (3) | WO2013096642A1 (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2250160B1 (en) | 2008-01-25 | 2015-11-11 | Millennium Pharmaceuticals, Inc. | Thiophenes and their use as phosphatidylinositol 3-kinase (pi3k) inhibitors |
| US8796314B2 (en) | 2009-01-30 | 2014-08-05 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| WO2010090716A1 (en) | 2009-01-30 | 2010-08-12 | Millennium Pharmaceuticals, Inc. | Heteroaryls and their use as pi3k inhibitors |
| US9090601B2 (en) | 2009-01-30 | 2015-07-28 | Millennium Pharmaceuticals, Inc. | Thiazole derivatives |
| US9062038B2 (en) | 2010-08-11 | 2015-06-23 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| WO2012021615A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| UY33554A (es) | 2010-08-11 | 2012-02-29 | Millennium Pharm Inc | Heteroarilos y usos de los mismos |
| BR112013009166A2 (pt) | 2010-10-13 | 2016-07-26 | Millennium Pharm Inc | heteroarilas e uso das mesmas. |
| EP3038622B1 (en) | 2013-08-28 | 2018-05-30 | Medivation Technologies LLC | Heterocyclic compounds and methods of use |
| CN105916503B (zh) | 2014-01-14 | 2020-04-14 | 米伦纽姆医药公司 | 杂芳基化合物和其用途 |
| JP2017502092A (ja) | 2014-01-14 | 2017-01-19 | ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | ヘテロアリール及びその使用 |
| WO2016050921A1 (en) * | 2014-10-02 | 2016-04-07 | F. Hoffmann-La Roche Ag | Pyrazole carboxamide compounds for use in the treament of disorders mediated by bruton's tyrosine kinase (btk) |
| WO2016141159A1 (en) | 2015-03-04 | 2016-09-09 | Medivation Technologies, Inc. | Srebp blockers for use in treating liver fibrosis, elevated cholesterol and insulin resistance |
| US10189826B2 (en) | 2015-03-04 | 2019-01-29 | Medivation Technologies Llc | Heterocyclic compounds and methods of use |
| TW201808906A (zh) | 2016-03-16 | 2018-03-16 | 拜耳作物科學股份有限公司 | 作為殺蟲劑之經取代吡啶化合物 |
| EP3284739A1 (de) | 2017-07-19 | 2018-02-21 | Bayer CropScience Aktiengesellschaft | Substituierte (het)arylverbindungen als schädlingsbekämpfungsmittel |
| SG11201913556SA (en) * | 2017-07-28 | 2020-02-27 | Yuhan Corp | Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same |
| CN111315742B (zh) | 2017-07-28 | 2023-09-01 | 株式会社柳韩洋行 | 制备氨基嘧啶衍生物的方法 |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| CN110041252A (zh) * | 2019-05-22 | 2019-07-23 | 南京合巨药业有限公司 | 一种2-氯-4-肼基吡啶的制备方法 |
| CN114867724B (zh) * | 2019-05-31 | 2025-11-07 | 班塔姆制药有限责任公司 | 用于制备噻唑基吡唑甲酸及其中间体的方法 |
| WO2021011723A1 (en) * | 2019-07-18 | 2021-01-21 | Avidence Therapeutics, Inc. | Anti-osteoarthritis hydantoin compounds and related compositions and methods |
| WO2025117722A1 (en) * | 2023-11-27 | 2025-06-05 | Rubedo Life Sciences, Inc. | Carbon linked bcl inhibitors and senolytic compounds and uses thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH27357A (en) * | 1989-09-22 | 1993-06-21 | Fujisawa Pharmaceutical Co | Pyrazole derivatives and pharmaceutical compositions comprising the same |
| IL104369A0 (en) * | 1992-01-13 | 1993-05-13 | Smithkline Beecham Corp | Novel compounds and compositions |
| GB2306108A (en) * | 1995-10-13 | 1997-04-30 | Merck & Co Inc | Treatment of Raf-mediated cancers with imidazole derivatives |
| DK1043995T3 (da) * | 1997-12-22 | 2007-03-05 | Bayer Pharmaceuticals Corp | Inhibering af p38 kinaseaktivitet ved anvendelse af aryl- og heteroaryl-substituerede, heterocykliske urinstoffer |
| CA2446864C (en) * | 2001-05-16 | 2011-02-15 | Vertex Pharmaceuticals Incorporated | Inhibitors of src and other protein kinases |
| ES2274986T3 (es) * | 2001-08-01 | 2007-06-01 | MERCK & CO., INC. | Derivados de benzimidazo 4,5-f/isoquinolinona. |
| US7582631B2 (en) * | 2004-01-14 | 2009-09-01 | Amgen Inc. | Substituted heterocyclic compounds and methods of use |
| AU2005319455A1 (en) * | 2004-12-21 | 2006-06-29 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| CA2594477C (en) * | 2005-01-21 | 2016-07-12 | Astex Therapeutics Limited | Pharmaceutical compounds |
| WO2008011557A2 (en) * | 2006-07-20 | 2008-01-24 | Borchardt Allen J | Heteroaryl inhibitors of rho kinase |
| UY30892A1 (es) * | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
| JP2010522770A (ja) * | 2007-03-29 | 2010-07-08 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | Ａｋｔ活性の阻害物質 |
| GB0709031D0 (en) * | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
| EP2183232B1 (en) * | 2007-08-02 | 2013-03-06 | Amgen, Inc | Pi3 kinase modulators and methods of use |
| BRPI0908906A2 (pt) * | 2008-03-21 | 2019-09-24 | Novartis Ag | compostos heterocíclicos e usos dos mesmos |
| AU2009260782B2 (en) * | 2008-06-19 | 2014-12-11 | Millennium Pharmaceuticals, Inc. | Thiophene or thiazole derivatives and their use as PI3K inhibitors |
| BRPI0913966A2 (pt) * | 2008-06-27 | 2015-11-17 | Novartis Ag | compostos orgânicos |
| WO2010090716A1 (en) * | 2009-01-30 | 2010-08-12 | Millennium Pharmaceuticals, Inc. | Heteroaryls and their use as pi3k inhibitors |
| WO2010127152A2 (en) * | 2009-04-29 | 2010-11-04 | Irm Llc | Compounds and compositions as microsomal prostaglandin e synthase-1 inhibitors |
| EP2430013B1 (en) * | 2009-05-13 | 2014-10-15 | Amgen Inc. | Heteroaryl compounds as pikk inhibitors |
| AR077975A1 (es) * | 2009-08-28 | 2011-10-05 | Irm Llc | Derivados de pirazol pirimidina y composiciones como inhibidores de cinasa de proteina |
| WO2011149874A2 (en) * | 2010-05-26 | 2011-12-01 | Schering Corporation | N-phenyl imidazole carboxamide inhibitors of 3-phosphoinositide-dependent protein kinase-1 |
| WO2012084678A1 (en) * | 2010-12-23 | 2012-06-28 | Syngenta Participations Ag | Novel imidazoles useful as plant fungicides |
| RU2013143747A (ru) * | 2011-03-21 | 2015-04-27 | Ф. Хоффманн-Ля Рош Аг | Соединения бензоксазепина, селективные в отношении pi3k p110 дельта и способы их применения |
| IN2014CN04676A (OSRAM) * | 2011-12-21 | 2015-09-18 | Ono Pharmaceutical Co |
-
2012
- 2012-12-20 WO PCT/US2012/070988 patent/WO2013096642A1/en not_active Ceased
- 2012-12-20 JP JP2014548902A patent/JP2015503505A/ja active Pending
- 2012-12-20 TW TW101148828A patent/TW201331194A/zh unknown
- 2012-12-20 EP EP12859324.1A patent/EP2793879A4/en not_active Withdrawn
- 2012-12-20 UY UY0001034539A patent/UY34539A/es not_active Application Discontinuation
- 2012-12-20 TW TW101148909A patent/TW201332989A/zh unknown
- 2012-12-20 JP JP2014548896A patent/JP2015503504A/ja active Pending
- 2012-12-20 UY UY0001034540A patent/UY34540A/es not_active Application Discontinuation
- 2012-12-20 WO PCT/US2012/070969 patent/WO2013096630A1/en not_active Ceased
- 2012-12-20 US US13/721,877 patent/US20130165472A1/en not_active Abandoned
- 2012-12-20 TW TW101148830A patent/TW201332988A/zh unknown
- 2012-12-20 UY UY0001034538A patent/UY34538A/es not_active Application Discontinuation
- 2012-12-20 WO PCT/US2012/070980 patent/WO2013096637A1/en not_active Ceased
- 2012-12-20 EP EP12860844.5A patent/EP2793880A4/en not_active Withdrawn
- 2012-12-20 JP JP2014548899A patent/JP2015506347A/ja active Pending
- 2012-12-20 US US13/722,222 patent/US20130165483A1/en not_active Abandoned
- 2012-12-20 EP EP12859082.5A patent/EP2793894A4/en not_active Withdrawn
- 2012-12-20 US US13/722,134 patent/US20130165464A1/en not_active Abandoned
- 2012-12-26 AR ARP120104957A patent/AR089446A1/es unknown
- 2012-12-26 AR ARP120104956A patent/AR089445A1/es unknown
- 2012-12-26 AR ARP120104958A patent/AR089447A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015506347A5 (OSRAM) | ||
| JP2015503505A5 (OSRAM) | ||
| JP2015503504A5 (OSRAM) | ||
| JP2011510080A5 (OSRAM) | ||
| CA2563895C (en) | Disalt inhibitors of il-12 production | |
| TWI457337B (zh) | 呋呫基苯并咪唑 | |
| JP2008513508A5 (OSRAM) | ||
| JP2013533318A5 (OSRAM) | ||
| JP2014512406A5 (OSRAM) | ||
| JP2016505063A (ja) | ソルチリン阻害剤としてのｎ置換された５置換フタルアミド酸 | |
| ES2824801T3 (es) | Sal de compuesto heterocíclico sustituido con halógeno | |
| KR20060123208A (ko) | 피라진 유도체 및 이의 약학적 용도 | |
| JP6666458B2 (ja) | 置換のアミノ６員窒素含有複素環式化合物およびその製造と使用 | |
| AU2006267454A2 (en) | Benzoimidazole compound capable of inhibiting prostaglandin D synthetase | |
| JP2016508152A (ja) | Ｃｒａｃチャネル阻害薬としての、ピラゾリルをベースとするカルボキサミド類ｉ | |
| WO2008152094A2 (en) | Substituted acetamides as modulators of the ep2 receptor | |
| CN106243047B (zh) | 具有VEGFR-2和B-raf双重抑制作用的喹喔啉酮双芳基脲及其衍生物、制备方法及其应用 | |
| US20100152240A1 (en) | Pyrroline-2-one derivatives against cell releasing tumor necrosis factor, preparation methods and uses thereof | |
| CN104334528A (zh) | (2-杂芳基氨基)琥珀酸衍生物 | |
| JP2016504397A (ja) | Ｃｒａｃチャネル阻害薬としての、ピラゾリルをベースとするカルボキサミド類ｉｉ | |
| JP2016513726A (ja) | がん細胞成長阻害剤としてのテトラヒドロイソキノリン−２−イル−（キナゾリン−４−イル）メタノン化合物 | |
| JP2008088107A (ja) | 新規ピリダジン誘導体 | |
| WO2017198179A1 (zh) | 新型噻唑类衍生物在治疗炎性肠病中的应用 | |
| JP6464244B2 (ja) | Ｔｅｒｔ−ブチル ｎ−［２−｛４−［６−アミノ−５−（２，４−ジフルオロベンゾイル）−２−オキソピリジン−１（２ｈ）−イル］−３，５−ジフルオロフェニル｝エチル）−ｌ−アラニネート又はその製薬上許容され得る塩、水和物もしくは溶媒和物 | |
| EP4017593B1 (en) | Bicyclic agonists of stimulator of interferon genes sting |