JP2015504909A5 - - Google Patents

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Publication number
JP2015504909A5
JP2015504909A5 JP2014553715A JP2014553715A JP2015504909A5 JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5 JP 2014553715 A JP2014553715 A JP 2014553715A JP 2014553715 A JP2014553715 A JP 2014553715A JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5
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JP
Japan
Prior art keywords
methyl
sulfane
galactopyranosyl
bis
benzopyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014553715A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015504909A (ja
JP6158840B2 (ja
Filing date
Publication date
Priority claimed from EP12152413.6A external-priority patent/EP2620443A1/en
Application filed filed Critical
Publication of JP2015504909A publication Critical patent/JP2015504909A/ja
Publication of JP2015504909A5 publication Critical patent/JP2015504909A5/ja
Application granted granted Critical
Publication of JP6158840B2 publication Critical patent/JP6158840B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014553715A 2012-01-25 2013-01-24 ガレクチンのガラクトシド阻害剤 Expired - Fee Related JP6158840B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12152413.6A EP2620443A1 (en) 2012-01-25 2012-01-25 Novel galactoside inhibitors of galectins
EP12152413.6 2012-01-25
PCT/EP2013/051339 WO2013110704A1 (en) 2012-01-25 2013-01-24 Novel galactoside inhibitors of galectins

Publications (3)

Publication Number Publication Date
JP2015504909A JP2015504909A (ja) 2015-02-16
JP2015504909A5 true JP2015504909A5 (https=) 2016-03-10
JP6158840B2 JP6158840B2 (ja) 2017-07-05

Family

ID=47598867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014553715A Expired - Fee Related JP6158840B2 (ja) 2012-01-25 2013-01-24 ガレクチンのガラクトシド阻害剤

Country Status (8)

Country Link
US (1) US9353141B2 (https=)
EP (2) EP2620443A1 (https=)
JP (1) JP6158840B2 (https=)
CN (1) CN104066743B (https=)
CA (1) CA2854986C (https=)
ES (1) ES2559857T3 (https=)
IN (1) IN2014DN05772A (https=)
WO (1) WO2013110704A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586438B2 (en) 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
BR0015294A (pt) 1999-11-03 2003-07-15 Bristol Myers Squibb Co Método para tratamento da diabetes
US9243021B2 (en) 2012-10-31 2016-01-26 Galecto Biotech Ab Galactoside inhibitor of galectins
EP2919802A4 (en) * 2012-11-15 2016-09-14 Univ Tufts METHOD, COMPOSITIONS AND KITS FOR TREATING, MODULATING OR PREVENTING ANGIOGENESIS OR FIBROSIS IN A PATIENT USING A GALECTINE PROTEIN HEMMER
US12390486B2 (en) 2012-12-20 2025-08-19 Henry Ford Health System Method for treating diastolic heart failure by inhibiting galectin-3
JP2016507503A (ja) 2012-12-20 2016-03-10 ヘンリー フォード ヘルス システム ガレクチン−3を阻害することによる拡張期心不全を治療する方法
JP6735680B2 (ja) * 2014-07-09 2020-08-05 ガレクト バイオテック エービー ガレクチンの新規ハイブリッドガラクトシド阻害剤
CA2970062C (en) * 2015-01-30 2023-02-28 Galecto Biotech Ab Alpha-d-galactoside inhibitors of galectins
MX394409B (es) * 2016-03-04 2025-03-24 Galectin Sciences Llc Compuestos de seleno-galactosida para la prevención y el tratamiento de las enfermedades asociadas con galectina y el uso de los mismos.
CA3025867A1 (en) * 2016-07-12 2018-01-18 Galecto Biotech Ab Alpha-d-galactoside inhibitors of galectins
US10988502B2 (en) * 2016-07-12 2021-04-27 Galecto Biotech Ab Alpha-D-galactoside inhibitors of galectins
EP3621973A4 (en) 2017-05-12 2021-10-27 Galectin Sciences, LLC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF DISEASES AND USES THEREOF
KR20200104889A (ko) 2017-12-29 2020-09-04 글리코미메틱스, 인크. E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제
US20210138080A1 (en) * 2018-06-29 2021-05-13 Glykos Biomedical Oy Conjugates
CA3122321A1 (en) 2018-12-27 2020-07-02 Glycomimetics, Inc. Galectin-3 inhibiting c-glycosides
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
WO2021028323A1 (en) * 2019-08-09 2021-02-18 Idorsia Pharmaceuticals Ltd (2-acetamidyl)thio-beta-d-galactopyranoside derivatives
WO2021123506A1 (en) 2019-12-18 2021-06-24 Glykos Biomedical Oy Stabile conjugate
CN116270672B (zh) * 2023-02-27 2026-03-27 江苏科技大学 β-D-硫代葡萄糖钠盐在制备缓解或治疗急性肾损伤的药物中的应用
CZ2023132A3 (cs) 2023-04-04 2024-10-16 Ústav Chemických Procesů Av Čr, V. V. I. Komplexy ruthenia pro inhibici galektinů, způsob jejich výroby a jejich použití

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0100172D0 (sv) 2001-01-22 2001-01-22 Ulf Nilsson New inhibitors against galectins
SE0401301D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel 3-triazolyl-galactoside inhibitors of galectins
SE0401300D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel Galactoside Inhibitors of Galectins
ES2543063T3 (es) 2008-05-16 2015-08-14 Galecto Biotech Ab Nueva síntesis de inhibidores de galactósidos
ES2652488T3 (es) 2009-04-28 2018-02-02 Galecto Biotech Ab Nuevos inhibidores de galactósidos de galectinas
CN104755088A (zh) 2012-10-31 2015-07-01 格莱克特生物技术公司 半乳凝集素-3的半乳糖苷抑制剂及其用于治疗肺纤维化的应用

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