JP2015503562A5 - - Google Patents
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- Publication number
- JP2015503562A5 JP2015503562A5 JP2014550353A JP2014550353A JP2015503562A5 JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5 JP 2014550353 A JP2014550353 A JP 2014550353A JP 2014550353 A JP2014550353 A JP 2014550353A JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- methyl
- condition
- carboxylic acid
- pyrazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161580474P | 2011-12-27 | 2011-12-27 | |
| US61/580,474 | 2011-12-27 | ||
| PCT/US2012/070664 WO2013101598A1 (en) | 2011-12-27 | 2012-12-19 | Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015503562A JP2015503562A (ja) | 2015-02-02 |
| JP2015503562A5 true JP2015503562A5 (https=) | 2016-02-18 |
| JP6132853B2 JP6132853B2 (ja) | 2017-05-24 |
Family
ID=47436293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014550353A Expired - Fee Related JP6132853B2 (ja) | 2011-12-27 | 2012-12-19 | 全身性抗炎症反応を提供する、複数のプロスタグランジン受容体で作用する化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9035071B2 (https=) |
| EP (1) | EP2797893B1 (https=) |
| JP (1) | JP6132853B2 (https=) |
| AU (1) | AU2012362724C1 (https=) |
| CA (1) | CA2862263C (https=) |
| WO (1) | WO2013101598A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8859606B2 (en) | 2010-07-01 | 2014-10-14 | Allergan, Inc. | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response |
| JP6403688B2 (ja) * | 2013-01-21 | 2018-10-10 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 全身性抗炎症反応を提供する複数のプロスタグランジン受容体で作用する化合物 |
| ITMI20132201A1 (it) * | 2013-12-23 | 2015-06-24 | Isagro Spa | Processo per la sintesi regioselettiva di pirazoli |
| CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| US20230390303A1 (en) | 2020-11-13 | 2023-12-07 | Ono Pharmaceutical Co., Ltd. | Cancer treatment by combination of ep4 antagonist and immune checkpoint inhibitor |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| DE19924872A1 (de) | 1999-05-29 | 2000-11-30 | Dresden Arzneimittel | Antikonvulsiv wirkende Pyrazolo[3,4-d][1,2,3]triazine und Verfahren zu ihrer Herstellung |
| US7217725B2 (en) | 2000-09-14 | 2007-05-15 | Allergan, Inc. | Prostaglandin D2 antagonist |
| US7273883B2 (en) | 2000-09-14 | 2007-09-25 | Allergan, Inc. | Prostaglandin EP4 antagonist |
| US6511999B2 (en) | 2000-09-14 | 2003-01-28 | Allergan, Inc. | Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists |
| ATE520694T1 (de) * | 2001-11-09 | 2011-09-15 | Gilead Palo Alto Inc | A2b-adenosinrezeptorantagonisten |
| WO2003042183A1 (en) | 2001-11-13 | 2003-05-22 | Takeda Chemical Industries, Ltd. | Process for production of pyrazole compounds |
| ES2298832T3 (es) | 2003-10-24 | 2008-05-16 | Glaxo Group Limited | Compuestos heterociclicos. |
| US7449473B2 (en) | 2003-10-31 | 2008-11-11 | Cv Therapeutics, Inc. | Substituted pyrrolo[3,2-d]pyrimidin-2,4-diones as A2b adenosine receptor antagonists |
| US7918014B2 (en) | 2005-07-13 | 2011-04-05 | Headway Technologies, Inc. | Method of manufacturing a CPP structure with enhanced GMR ratio |
| WO2007014054A2 (en) * | 2005-07-22 | 2007-02-01 | Glaxo Group Limted | Benzenesulfonamide inhibitor of ccr2 chemokine receptor |
| WO2008033455A2 (en) | 2006-09-13 | 2008-03-20 | The Institutes For Pharmaceutical Discovery, Llc | Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors |
| US20110046137A1 (en) * | 2007-05-10 | 2011-02-24 | Glaxo Group Limited | Pyrazole Derivatives as P2X7 Modulators |
| JP2010248183A (ja) * | 2009-03-26 | 2010-11-04 | Takeda Chem Ind Ltd | 複素環化合物 |
| GEP20146177B (en) * | 2010-01-27 | 2014-10-10 | Boehringer Ingelheim Int | Pyrazole compounds as crth2 antagonists |
| US8492424B2 (en) * | 2010-07-01 | 2013-07-23 | Allergan, Inc. | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response |
| EP2457900A1 (en) * | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| JP5999387B2 (ja) * | 2011-03-25 | 2016-09-28 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｒｔｈ２拮抗薬としてのピラゾール化合物 |
-
2012
- 2012-12-19 CA CA2862263A patent/CA2862263C/en active Active
- 2012-12-19 US US13/720,488 patent/US9035071B2/en active Active
- 2012-12-19 EP EP12806860.8A patent/EP2797893B1/en not_active Not-in-force
- 2012-12-19 AU AU2012362724A patent/AU2012362724C1/en not_active Ceased
- 2012-12-19 JP JP2014550353A patent/JP6132853B2/ja not_active Expired - Fee Related
- 2012-12-19 WO PCT/US2012/070664 patent/WO2013101598A1/en not_active Ceased
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