JP2015503562A5 - - Google Patents

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Publication number
JP2015503562A5
JP2015503562A5 JP2014550353A JP2014550353A JP2015503562A5 JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5 JP 2014550353 A JP2014550353 A JP 2014550353A JP 2014550353 A JP2014550353 A JP 2014550353A JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5
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JP
Japan
Prior art keywords
disease
methyl
condition
carboxylic acid
pyrazole
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Application number
JP2014550353A
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English (en)
Japanese (ja)
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JP2015503562A (ja
JP6132853B2 (ja
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Priority claimed from PCT/US2012/070664 external-priority patent/WO2013101598A1/en
Publication of JP2015503562A publication Critical patent/JP2015503562A/ja
Publication of JP2015503562A5 publication Critical patent/JP2015503562A5/ja
Application granted granted Critical
Publication of JP6132853B2 publication Critical patent/JP6132853B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014550353A 2011-12-27 2012-12-19 全身性抗炎症反応を提供する、複数のプロスタグランジン受容体で作用する化合物 Expired - Fee Related JP6132853B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161580474P 2011-12-27 2011-12-27
US61/580,474 2011-12-27
PCT/US2012/070664 WO2013101598A1 (en) 2011-12-27 2012-12-19 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response

Publications (3)

Publication Number Publication Date
JP2015503562A JP2015503562A (ja) 2015-02-02
JP2015503562A5 true JP2015503562A5 (https=) 2016-02-18
JP6132853B2 JP6132853B2 (ja) 2017-05-24

Family

ID=47436293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014550353A Expired - Fee Related JP6132853B2 (ja) 2011-12-27 2012-12-19 全身性抗炎症反応を提供する、複数のプロスタグランジン受容体で作用する化合物

Country Status (6)

Country Link
US (1) US9035071B2 (https=)
EP (1) EP2797893B1 (https=)
JP (1) JP6132853B2 (https=)
AU (1) AU2012362724C1 (https=)
CA (1) CA2862263C (https=)
WO (1) WO2013101598A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8859606B2 (en) 2010-07-01 2014-10-14 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
CA2898720A1 (en) * 2013-01-21 2014-07-24 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
ITMI20132201A1 (it) * 2013-12-23 2015-06-24 Isagro Spa Processo per la sintesi regioselettiva di pirazoli
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
US20230390303A1 (en) 2020-11-13 2023-12-07 Ono Pharmaceutical Co., Ltd. Cancer treatment by combination of ep4 antagonist and immune checkpoint inhibitor

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
DE19924872A1 (de) 1999-05-29 2000-11-30 Dresden Arzneimittel Antikonvulsiv wirkende Pyrazolo[3,4-d][1,2,3]triazine und Verfahren zu ihrer Herstellung
US7217725B2 (en) 2000-09-14 2007-05-15 Allergan, Inc. Prostaglandin D2 antagonist
US7273883B2 (en) 2000-09-14 2007-09-25 Allergan, Inc. Prostaglandin EP4 antagonist
US6511999B2 (en) 2000-09-14 2003-01-28 Allergan, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
DK1444233T3 (da) * 2001-11-09 2011-10-17 Gilead Palo Alto Inc A2B-adenosinreceptorantagonister
US20050014813A1 (en) 2001-11-13 2005-01-20 Hiroyuki Tawada Process for production of pyrazole compounds
ES2298832T3 (es) * 2003-10-24 2008-05-16 Glaxo Group Limited Compuestos heterociclicos.
CA2544193C (en) * 2003-10-31 2012-03-27 Cv Therapeutics, Inc. A2b adenosine receptor antagonists
US7918014B2 (en) 2005-07-13 2011-04-05 Headway Technologies, Inc. Method of manufacturing a CPP structure with enhanced GMR ratio
WO2007014054A2 (en) * 2005-07-22 2007-02-01 Glaxo Group Limted Benzenesulfonamide inhibitor of ccr2 chemokine receptor
WO2008033455A2 (en) * 2006-09-13 2008-03-20 The Institutes For Pharmaceutical Discovery, Llc Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors
DE602008005582D1 (de) 2007-05-10 2011-04-28 Glaxo Group Ltd Pyrazolderivate als p2x7-modulatoren
JP2010248183A (ja) * 2009-03-26 2010-11-04 Takeda Chem Ind Ltd 複素環化合物
HRP20150898T1 (hr) * 2010-01-27 2015-10-09 Boehringer Ingelheim International Gmbh Spojevi pirazola kao antagonisti crth2
US8492424B2 (en) * 2010-07-01 2013-07-23 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
EP2457900A1 (en) * 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
WO2012130633A1 (en) 2011-03-25 2012-10-04 Boehringer Ingelheim International Gmbh Pyrazole compounds as crth2 antagonists

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