JP2015172587A5 - - Google Patents
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- JP2015172587A5 JP2015172587A5 JP2015094454A JP2015094454A JP2015172587A5 JP 2015172587 A5 JP2015172587 A5 JP 2015172587A5 JP 2015094454 A JP2015094454 A JP 2015094454A JP 2015094454 A JP2015094454 A JP 2015094454A JP 2015172587 A5 JP2015172587 A5 JP 2015172587A5
- Authority
- JP
- Japan
- Prior art keywords
- gfap
- marker
- sbdp
- binding agent
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21872709P | 2009-06-19 | 2009-06-19 | |
| US61/218,727 | 2009-06-19 | ||
| US34518810P | 2010-05-17 | 2010-05-17 | |
| US61/345,188 | 2010-05-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516369A Division JP5875514B2 (ja) | 2009-06-19 | 2010-06-21 | 神経学的状態のバイオマーカーアッセイ |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017007752A Division JP6408041B2 (ja) | 2009-06-19 | 2017-01-19 | 神経学的状態のバイオマーカーアッセイ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015172587A JP2015172587A (ja) | 2015-10-01 |
| JP2015172587A5 true JP2015172587A5 (https=) | 2015-12-10 |
Family
ID=43357089
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516369A Active JP5875514B2 (ja) | 2009-06-19 | 2010-06-21 | 神経学的状態のバイオマーカーアッセイ |
| JP2015094454A Pending JP2015172587A (ja) | 2009-06-19 | 2015-05-01 | 神経学的状態のバイオマーカーアッセイ |
| JP2017007752A Active JP6408041B2 (ja) | 2009-06-19 | 2017-01-19 | 神経学的状態のバイオマーカーアッセイ |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516369A Active JP5875514B2 (ja) | 2009-06-19 | 2010-06-21 | 神経学的状態のバイオマーカーアッセイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017007752A Active JP6408041B2 (ja) | 2009-06-19 | 2017-01-19 | 神経学的状態のバイオマーカーアッセイ |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20130029859A1 (https=) |
| EP (2) | EP3355059A3 (https=) |
| JP (3) | JP5875514B2 (https=) |
| AU (1) | AU2010262952B2 (https=) |
| CA (1) | CA2766057A1 (https=) |
| WO (1) | WO2010148391A2 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8492107B2 (en) | 2004-04-15 | 2013-07-23 | University Of Florida Research Foundation, Inc. | Neural proteins as biomarkers for nervous system injury and other neural disorders |
| ES2665245T3 (es) | 2008-08-11 | 2018-04-25 | Banyan Biomarkers, Inc. | Proceso de detección de biomarcador y ensayo de estado neurológico |
| US12601749B2 (en) | 2008-08-11 | 2026-04-14 | Banyan Biomarkers, Inc. | Biomarker detection process and assay of neurological condition |
| WO2011032155A2 (en) | 2009-09-14 | 2011-03-17 | Banyan Biomarkers, Inc. | Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury |
| WO2012141674A2 (en) | 2010-01-26 | 2012-10-18 | Banyan Biomarkers, Inc. | Compositions and methods relating to argininosuccinate synthetase |
| JP2013524220A (ja) * | 2010-04-01 | 2013-06-17 | バンヤン・バイオマーカーズ・インコーポレイテッド | 神経毒性を検出するためのマーカーおよびアッセイ |
| US9709573B2 (en) | 2012-03-13 | 2017-07-18 | The Johns Hopkins University | Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration |
| EP3022322A4 (en) * | 2013-07-17 | 2017-05-17 | The Johns Hopkins University | A multi-protein biomarker assay for brain injury detection and outcome |
| US20170023591A1 (en) * | 2014-04-07 | 2017-01-26 | Iron Horse Diagnostics, Inc. | Traumatic Brain Injury and Neurodegenerative Biomarkers, Methods, and Systems |
| WO2016055148A2 (en) * | 2014-10-06 | 2016-04-14 | Université De Genève | Markers and their use in brain injury |
| JP2018510359A (ja) | 2015-02-05 | 2018-04-12 | イミューンアレイ ユーエスエイ インコーポレイテッド | 脳損傷または神経変性を診断するための方法および組成物 |
| CN107864671A (zh) | 2015-05-05 | 2018-03-30 | 加利福尼亚大学董事会 | 星形细胞创伤节和神经创伤生物标志物 |
| EP3479121A4 (en) * | 2016-06-30 | 2020-03-11 | Brainbox Solutions, Inc. | CONCENTRATIONS OF CIRCULATING BIOMARKERS FOR DIAGNOSIS AND RISK STRATIFICATION OF SKULL BRAIN TRAUMATA |
| JP2019535015A (ja) * | 2016-10-03 | 2019-12-05 | アボット・ラボラトリーズAbbott Laboratories | 患者サンプルにおけるgfap状況を評価する改善された方法 |
| WO2018081649A1 (en) | 2016-10-28 | 2018-05-03 | Banyan Biomarkers, Inc. | Antibodies to ubiquitin c-terminal hydrolase l1 (uch-l1) and glial fibrillary acidic protein (gfap) and related methods |
| CN106568750B (zh) * | 2016-10-31 | 2019-12-03 | 陕西脉元生物科技有限公司 | 一种基于荧光能量共振转移法的gfap检测方法 |
| EP3602069A1 (en) * | 2017-03-23 | 2020-02-05 | Abbott Laboratories | Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1 |
| US11016092B2 (en) | 2017-03-23 | 2021-05-25 | Abbott Laboratories | Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase L1 |
| BR112019021612A2 (pt) | 2017-04-15 | 2020-05-12 | Abbott Laboratories | Métodos para auxiliar o diagnóstico hiperagudo e determinação de traumatismo crânioencefálico em um indivíduo humano com o uso de biomarcadores precoces |
| US10877038B2 (en) | 2017-04-28 | 2020-12-29 | Abbott Laboratories | Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject |
| WO2018217792A1 (en) | 2017-05-23 | 2018-11-29 | Immunarray USA, Inc. | Biomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma |
| JP7416625B2 (ja) | 2017-05-25 | 2024-01-17 | アボット・ラボラトリーズ | 早期バイオマーカーを使用する、頭部への損傷を負ったヒト対象又は負った可能性があるヒト対象に対して、イメージングを実施するかどうかの決定の一助となるための方法 |
| BR112019025313A2 (pt) | 2017-05-30 | 2020-06-23 | Abbott Laboratories | Métodos para auxílio no diagnóstico e avaliação de uma lesão cerebral traumática leve em um indivíduo humano usando troponina cardíaca i |
| JP7454945B2 (ja) | 2017-07-03 | 2024-03-25 | アボット・ラボラトリーズ | 血液中のユビキチンカルボキシ末端ヒドロラーゼl1レベルを測定するための、改善された方法 |
| US11016105B2 (en) | 2017-12-09 | 2021-05-25 | Abbott Laboratories | Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of GFAP and UCH-L1 |
| US11022617B2 (en) | 2017-12-09 | 2021-06-01 | Abbott Laboratories | Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (TBI), using glial fibrillary acidic protein (GFAP) and/or ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) |
| CA3084064A1 (en) * | 2017-12-29 | 2019-07-04 | Abbott Laboratories | Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury |
| EP4465051A3 (en) * | 2018-05-29 | 2025-01-22 | Cognizance Biomarkers, Inc. | Biomarkers and methods for evaluation and treatment of epileptic vs non-epileptic seizures / no seizures / psychogenic non-epileptic seizures |
| KR102072563B1 (ko) * | 2018-06-27 | 2020-02-03 | 가톨릭대학교 산학협력단 | Dpysl2를 포함하는 인터넷 게임 장애 진단용 바이오마커 및 그의 용도 |
| EP4081804A1 (en) * | 2019-12-23 | 2022-11-02 | Albert-Ludwigs-Universität Freiburg | Gut microbiota-related methods for treating dementia and age-dependent cognitive decline |
| KR102464243B1 (ko) * | 2020-04-01 | 2022-11-08 | 프리시젼바이오 주식회사 | 외상성 뇌손상 바이오마커 검출용 시분해 형광분석 측방유동 분석장치 및 이를 이용한 외상성 뇌손상 바이오마커 측정방법 |
| KR102357260B1 (ko) * | 2020-12-10 | 2022-02-08 | 주식회사 레피겐엠디 | 마이크로rna를 이용한 당뇨병성 신경병증의 예측 및 진단 방법 및 이를 위한 키트 |
| CN113238045B (zh) * | 2021-04-27 | 2021-12-28 | 南方医科大学南方医院 | Crmp2及抗crmp2抗体的应用 |
| KR102759445B1 (ko) * | 2021-11-16 | 2025-01-24 | 한국한의학연구원 | 치료에 따른 보행 장애 개선 판별용 바이오마커 및 이의 용도 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270163A (en) | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
| US5683867A (en) | 1990-06-11 | 1997-11-04 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: blended SELEX |
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US5637459A (en) | 1990-06-11 | 1997-06-10 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chimeric selex |
| US5567588A (en) | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
| US5707796A (en) | 1990-06-11 | 1998-01-13 | Nexstar Pharmaceuticals, Inc. | Method for selecting nucleic acids on the basis of structure |
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US5496938A (en) | 1990-06-11 | 1996-03-05 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands to HIV-RT and HIV-1 rev |
| EP0786469B1 (en) | 1990-06-11 | 2006-03-01 | Gilead Sciences, Inc. | Methods of use of nucleic acid ligands |
| JP2005522669A (ja) * | 2001-08-20 | 2005-07-28 | バイオサイト インコーポレイテッド | 卒中および脳損傷の診断マーカーおよびその使用方法 |
| WO2003032894A2 (en) * | 2001-10-12 | 2003-04-24 | Pfizer Products Inc. | Method of monitoring neuroprotective treatment |
| CA2498614C (en) * | 2002-09-11 | 2013-04-16 | University Of Florida | Analyzing nerve cell damage |
| DK2357477T3 (en) * | 2003-09-20 | 2018-02-05 | Electrophoretics Ltd | Diagnostic approach for brain injury-related disorders based on detection of NDKA |
| EP1519194A1 (en) * | 2003-09-24 | 2005-03-30 | Roche Diagnostics GmbH | Use of gfap for identification of intracerebral hemorrhage |
| EP2207033B1 (en) * | 2004-04-15 | 2014-06-18 | University of Florida Research Foundation, Inc. | Neural proteins as biomarkers for nervous system injury and other neural disorders |
| WO2008008819A2 (en) * | 2006-07-11 | 2008-01-17 | University Of Florida Research Foundation, Inc. | Diagnosis and treatment of neurological inflammation |
| CA2668640A1 (en) * | 2006-11-01 | 2008-05-29 | George Mason Intellectual Properties, Inc. | Biomarkers for neurological conditions |
| US8293489B2 (en) * | 2007-01-31 | 2012-10-23 | Henkin Robert I | Methods for detection of biological substances |
| JP2009052933A (ja) * | 2007-08-24 | 2009-03-12 | Rakuno Gakuen | プリオン病の検出方法及び診断キット |
| CN101983337A (zh) * | 2008-02-04 | 2011-03-02 | 班扬生物标记公司 | 用于诊断或治疗脑损伤的方法 |
| ES2665245T3 (es) * | 2008-08-11 | 2018-04-25 | Banyan Biomarkers, Inc. | Proceso de detección de biomarcador y ensayo de estado neurológico |
| WO2011032155A2 (en) * | 2009-09-14 | 2011-03-17 | Banyan Biomarkers, Inc. | Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury |
-
2010
- 2010-06-21 EP EP18162020.4A patent/EP3355059A3/en not_active Withdrawn
- 2010-06-21 US US13/379,164 patent/US20130029859A1/en not_active Abandoned
- 2010-06-21 EP EP10790319A patent/EP2443461A4/en not_active Ceased
- 2010-06-21 AU AU2010262952A patent/AU2010262952B2/en active Active
- 2010-06-21 CA CA2766057A patent/CA2766057A1/en not_active Abandoned
- 2010-06-21 JP JP2012516369A patent/JP5875514B2/ja active Active
- 2010-06-21 WO PCT/US2010/039335 patent/WO2010148391A2/en not_active Ceased
-
2015
- 2015-05-01 JP JP2015094454A patent/JP2015172587A/ja active Pending
-
2017
- 2017-01-19 JP JP2017007752A patent/JP6408041B2/ja active Active
- 2017-02-23 US US15/441,183 patent/US20190064187A1/en not_active Abandoned
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