JP2015134777A5 - - Google Patents
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- Publication number
- JP2015134777A5 JP2015134777A5 JP2015022587A JP2015022587A JP2015134777A5 JP 2015134777 A5 JP2015134777 A5 JP 2015134777A5 JP 2015022587 A JP2015022587 A JP 2015022587A JP 2015022587 A JP2015022587 A JP 2015022587A JP 2015134777 A5 JP2015134777 A5 JP 2015134777A5
- Authority
- JP
- Japan
- Prior art keywords
- lys
- gly
- acid
- peptide
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 9
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims 6
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- -1 aliphatic radical Chemical class 0.000 claims 4
- 239000002537 cosmetic Substances 0.000 claims 4
- OIQXFRANQVWXJF-QBFSEMIESA-N (2z)-2-benzylidene-4,7,7-trimethylbicyclo[2.2.1]heptan-3-one Chemical class CC1(C)C2CCC1(C)C(=O)\C2=C/C1=CC=CC=C1 OIQXFRANQVWXJF-QBFSEMIESA-N 0.000 claims 3
- 201000004384 Alopecia Diseases 0.000 claims 3
- 235000021314 Palmitic acid Nutrition 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 3
- 231100000360 alopecia Toxicity 0.000 claims 3
- 229960004050 aminobenzoic acid Drugs 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims 3
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 claims 2
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 claims 2
- 125000001931 aliphatic group Chemical group 0.000 claims 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 235000015872 dietary supplement Nutrition 0.000 claims 2
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims 2
- 235000019136 lipoic acid Nutrition 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000863 peptide conjugate Substances 0.000 claims 2
- 150000003902 salicylic acid esters Chemical class 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 229960002663 thioctic acid Drugs 0.000 claims 2
- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 claims 2
- HEOCBCNFKCOKBX-RELGSGGGSA-N (1s,2e,4r)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-3-one Chemical group C1=CC(C)=CC=C1\C=C/1C(=O)[C@]2(C)CC[C@H]\1C2(C)C HEOCBCNFKCOKBX-RELGSGGGSA-N 0.000 claims 1
- RRJOMESUBQAYOA-BZSNNMDCSA-N (2S)-2-[[(2S)-2-[[2-[[(2S)-2-acetamido-6-aminohexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanamide Chemical compound NCCCC[C@H](NC(=O)C)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(N)=O)CC1=CN=CN1 RRJOMESUBQAYOA-BZSNNMDCSA-N 0.000 claims 1
- JFOWDKWFHZIMTR-RUCXOUQFSA-N (2s)-2-aminopentanedioic acid;(2s)-2,5-diamino-5-oxopentanoic acid Chemical group OC(=O)[C@@H](N)CCC(N)=O.OC(=O)[C@@H](N)CCC(O)=O JFOWDKWFHZIMTR-RUCXOUQFSA-N 0.000 claims 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims 1
- QLAJNZSPVITUCQ-UHFFFAOYSA-N 1,3,2-dioxathietane 2,2-dioxide Chemical compound O=S1(=O)OCO1 QLAJNZSPVITUCQ-UHFFFAOYSA-N 0.000 claims 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 1
- LSHGMOIQPURPAK-UHFFFAOYSA-N 2-benzylidene-1,4,7,7-tetramethylbicyclo[2.2.1]heptan-3-one Chemical compound CC1(C)C(C2=O)(C)CCC1(C)C2=CC1=CC=CC=C1 LSHGMOIQPURPAK-UHFFFAOYSA-N 0.000 claims 1
- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 claims 1
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical group C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 claims 1
- WSSJONWNBBTCMG-UHFFFAOYSA-N 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester Chemical group C1C(C)(C)CC(C)CC1OC(=O)C1=CC=CC=C1O WSSJONWNBBTCMG-UHFFFAOYSA-N 0.000 claims 1
- ORWUQAQITKSSRZ-UHFFFAOYSA-N 2-hydroxyethyl 4-[bis[2-(2-hydroxyethoxy)ethyl]amino]benzoate Chemical compound OCCOCCN(CCOCCO)C1=CC=C(C(=O)OCCO)C=C1 ORWUQAQITKSSRZ-UHFFFAOYSA-N 0.000 claims 1
- 229940113178 5 Alpha reductase inhibitor Drugs 0.000 claims 1
- 239000002677 5-alpha reductase inhibitor Substances 0.000 claims 1
- 241000723346 Cinnamomum camphora Species 0.000 claims 1
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims 1
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 claims 1
- 235000021360 Myristic acid Nutrition 0.000 claims 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N Myristic acid Natural products CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 claims 1
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical group CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims 1
- WYWZRNAHINYAEF-UHFFFAOYSA-N Padimate O Chemical group CCCCC(CC)COC(=O)C1=CC=C(N(C)C)C=C1 WYWZRNAHINYAEF-UHFFFAOYSA-N 0.000 claims 1
- 235000011054 acetic acid Nutrition 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229960001716 benzalkonium Drugs 0.000 claims 1
- CYDRXTMLKJDRQH-UHFFFAOYSA-N benzododecinium Chemical compound CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 CYDRXTMLKJDRQH-UHFFFAOYSA-N 0.000 claims 1
- 229960000846 camphor Drugs 0.000 claims 1
- 229930008380 camphor Natural products 0.000 claims 1
- 229940114081 cinnamate Drugs 0.000 claims 1
- 229930016911 cinnamic acid Natural products 0.000 claims 1
- 235000013985 cinnamic acid Nutrition 0.000 claims 1
- 229960004697 enzacamene Drugs 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 229940068171 ethyl hexyl salicylate Drugs 0.000 claims 1
- 229960004881 homosalate Drugs 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 claims 1
- 229960003632 minoxidil Drugs 0.000 claims 1
- 229960003512 nicotinic acid Drugs 0.000 claims 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N nicotinic acid Natural products OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims 1
- 235000001968 nicotinic acid Nutrition 0.000 claims 1
- 239000011664 nicotinic acid Substances 0.000 claims 1
- 229960001679 octinoxate Drugs 0.000 claims 1
- FMJSMJQBSVNSBF-UHFFFAOYSA-N octocrylene Chemical group C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 claims 1
- 229960000601 octocrylene Drugs 0.000 claims 1
- AFDXODALSZRGIH-UHFFFAOYSA-N p-coumaric acid methyl ether Natural products COC1=CC=C(C=CC(O)=O)C=C1 AFDXODALSZRGIH-UHFFFAOYSA-N 0.000 claims 1
- 229920002401 polyacrylamide Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 229930002330 retinoic acid Natural products 0.000 claims 1
- 229960003471 retinol Drugs 0.000 claims 1
- 235000020944 retinol Nutrition 0.000 claims 1
- 239000011607 retinol Substances 0.000 claims 1
- 210000004761 scalp Anatomy 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 229960001727 tretinoin Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR03/08801 | 2003-07-18 | ||
| FR0308801A FR2857597B1 (fr) | 2003-07-18 | 2003-07-18 | Utilisation de conjugues peptidiques pour la preparation de compositions destinees au traitement preventif et curatif de l'alopecie. |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012178403A Division JP6006582B2 (ja) | 2003-07-18 | 2012-08-10 | 脱毛症の予防および治療的処置用組成物の製造のためのペプチド複合体の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015134777A JP2015134777A (ja) | 2015-07-27 |
| JP2015134777A5 true JP2015134777A5 (enExample) | 2015-09-03 |
| JP6149053B2 JP6149053B2 (ja) | 2017-06-14 |
Family
ID=33548254
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006519970A Pending JP2007516209A (ja) | 2003-07-18 | 2004-07-16 | 脱毛症の予防および治療的処置用組成物の製造のためのペプチド複合体の使用 |
| JP2012178403A Expired - Lifetime JP6006582B2 (ja) | 2003-07-18 | 2012-08-10 | 脱毛症の予防および治療的処置用組成物の製造のためのペプチド複合体の使用 |
| JP2015022587A Expired - Lifetime JP6149053B2 (ja) | 2003-07-18 | 2015-02-06 | 脱毛症の予防および治療的処置用組成物の製造のためのペプチド複合体の使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006519970A Pending JP2007516209A (ja) | 2003-07-18 | 2004-07-16 | 脱毛症の予防および治療的処置用組成物の製造のためのペプチド複合体の使用 |
| JP2012178403A Expired - Lifetime JP6006582B2 (ja) | 2003-07-18 | 2012-08-10 | 脱毛症の予防および治療的処置用組成物の製造のためのペプチド複合体の使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7507719B2 (enExample) |
| EP (1) | EP1663285B1 (enExample) |
| JP (3) | JP2007516209A (enExample) |
| CA (1) | CA2532679C (enExample) |
| ES (1) | ES2401686T3 (enExample) |
| FR (1) | FR2857597B1 (enExample) |
| WO (1) | WO2005009456A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2009014233A (es) * | 2007-06-29 | 2010-03-10 | Innovactiv Inc | Compuestos novedosos, uso de los mismos en aplicaciones cosmoceuticas y cosmeticas y composiciones que comprenden los mismos. |
| US20100310484A1 (en) * | 2007-06-29 | 2010-12-09 | Innovactiv Inc. | Novel peptides, use thereof in cosmetic and cosmeceutic applications, and compositions comprising same |
| PT2165698E (pt) | 2008-09-18 | 2016-06-23 | Universkin | Composição cosmética para cuidar a pele agredida |
| WO2014120793A1 (en) * | 2013-01-30 | 2014-08-07 | The Beauty Cartel, Llc. | Hair loss treatment compositions and methods of making and using same |
| KR101578901B1 (ko) * | 2013-09-11 | 2015-12-28 | (주)셀아이콘랩 | 발모 촉진 펩타이드, 이의 제조방법, 및, 이를 함유하는 탈모방지 또는 발모촉진용 조성물 |
| FR3020951B1 (fr) * | 2014-05-16 | 2016-06-17 | Pierre Fabre Dermo Cosmetique | Association d'un tetrapeptide et d'un glyceryl ester pour le traitement de l'alopecie androgenique. |
| ES2882102T3 (es) * | 2015-08-21 | 2021-12-01 | A Novation Cosmetics Gmbh | Combinaciones activas, composiciones y métodos para mejorar el crecimiento del pelo |
| FR3042192B1 (fr) | 2015-10-09 | 2017-12-08 | Inst Europeen De Biologie Cellulaire | Peptides utiles dans le traitement preventif et curatif de l'alopecie |
| FR3052453B1 (fr) * | 2016-06-14 | 2018-05-18 | Sederma | Peptide, composition le comprenant et utilisations notamment cosmetiques |
| KR101948238B1 (ko) * | 2016-08-19 | 2019-02-14 | (주)케어젠 | 미녹시딜과 펩타이드의 결합체 |
| KR102160566B1 (ko) * | 2019-01-16 | 2020-09-28 | (주)케어젠 | 미녹시딜과 펩타이드의 결합체 |
| KR102697851B1 (ko) * | 2021-07-29 | 2024-08-22 | (주)젠퓨어 | 탈모방지용 화장료 조성물 |
| KR20250057208A (ko) * | 2023-10-19 | 2025-04-29 | 주식회사 바이오빛 | 재조합 폴리펩티드를 포함하는 탈모 방지 또는 발모 촉진용 조성물 |
| FR3158043A1 (fr) * | 2024-01-09 | 2025-07-11 | Lucas Meyer Cosmetics | Combinaison d’actifs cosmétiques pour maintenir ou rééquilibrer le microbiote cutané |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5120831A (en) * | 1985-02-08 | 1992-06-09 | Procyte Corporation | Metal-peptide compositions |
| US4810693A (en) * | 1985-02-08 | 1989-03-07 | Procyte Corporation | Method for inducing biological coverings in wounds |
| US4665054A (en) * | 1985-02-08 | 1987-05-12 | Bioheal, Inc. | Chemical derivatives of GHL-Cu |
| US5470876A (en) * | 1985-07-18 | 1995-11-28 | Proctor; Peter H. | Topical sod for treating hair loss |
| DE3851203T2 (de) * | 1987-05-11 | 1994-12-15 | Procyte Corp | Gebrauch von GHL-Cu Derivaten für die Herstellung eines Medikaments zur Stimulierung des Haarwachstums. |
| EP0293837B1 (en) | 1987-06-01 | 1992-01-15 | Keikichi Sugiyama | Composition for application to hair or scalp |
| DE4127790A1 (de) * | 1991-08-22 | 1993-02-25 | Wank Anna | Verwendung von oligopeptiden mit 2 bis 5 peptidbindungen fuer kosmetische zwecke und einige neue oligopeptid-metallkomplexe |
| JPH06305941A (ja) * | 1993-04-15 | 1994-11-01 | Procyte Corp | 毛の成長を促進する医薬及び化粧品 |
| WO1995023580A1 (en) * | 1994-03-03 | 1995-09-08 | Procyte Corporation | Preventive and remedy for secondary depilation |
| JP3425813B2 (ja) * | 1994-11-28 | 2003-07-14 | 明治乳業株式会社 | ゲル化食品組成物 |
| FR2733421B1 (fr) | 1995-04-28 | 1997-06-06 | Oreal | Utilisation de derives de l'hormone stimulatrice des melanocytes de type alpha pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
| FR2741075B1 (fr) * | 1995-11-15 | 1998-01-30 | Rech De Pathologie Appliquee S | Conjugues peptidiques, leur utilisation a titre de medicament et compositions les contenant |
| FR2741076B1 (fr) * | 1995-11-15 | 1998-01-30 | Rech De Pathologie Appliquee S | Conjugues peptidiques derives des hormones thymiques, leur utilisation a titre de medicament et compositions les contenant |
| JPH107698A (ja) | 1996-04-24 | 1998-01-13 | Sumitomo Electric Ind Ltd | エピモルフィン・アンタゴニスト |
| JP3903503B2 (ja) | 1996-11-18 | 2007-04-11 | 住友電気工業株式会社 | 可溶性ポリペプチド |
| FR2791684B1 (fr) * | 1999-03-30 | 2001-05-11 | Sederma Sa | Composition cosmetiques ou dermopharmaceutiques contenant le tripeptide n-n-biotinyl-gly-his-lys pour prevenir, reduire ou supprimer la chute des cheveux ainsi que pour favoriser leur repousse |
| WO2001098348A2 (en) | 2000-06-22 | 2001-12-27 | Holick Michael F | Regulation of cellproliferation and differentiation using topically applied peptides |
| CA2462791A1 (en) * | 2001-10-05 | 2003-04-17 | Procyte Corporation | Skin care compositions containing peptide copper complexes and retinol, retinol derivatives, or a mixture thereof |
-
2003
- 2003-07-18 FR FR0308801A patent/FR2857597B1/fr not_active Expired - Lifetime
-
2004
- 2004-07-16 ES ES04767703T patent/ES2401686T3/es not_active Expired - Lifetime
- 2004-07-16 WO PCT/FR2004/001879 patent/WO2005009456A2/fr not_active Ceased
- 2004-07-16 CA CA2532679A patent/CA2532679C/fr not_active Expired - Lifetime
- 2004-07-16 US US10/565,007 patent/US7507719B2/en not_active Expired - Lifetime
- 2004-07-16 JP JP2006519970A patent/JP2007516209A/ja active Pending
- 2004-07-16 EP EP04767703A patent/EP1663285B1/fr not_active Expired - Lifetime
-
2012
- 2012-08-10 JP JP2012178403A patent/JP6006582B2/ja not_active Expired - Lifetime
-
2015
- 2015-02-06 JP JP2015022587A patent/JP6149053B2/ja not_active Expired - Lifetime
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