JP2015111112A - Cassette for medical examination, and paraffin block preparation tool - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cassette for medical examination capable of preventing occurrence of burrs and capable of easily mounting an embedding tray on a bottom part of a cassette body, and to provide a paraffin block preparation tool including the cassette for medical examination.SOLUTION: A cassette 1 for medical examination includes: a cassette body 2 which is a rectangular container opened upward and has many through-holes 2a on its bottom part; and a lid body 3 which has many through-holes 3a. On a rear surface of the bottom part 2b of the cassette body 2, fitting parts 2c are provided at positions with which the edge part of an embedding tray contacts. A paraffin block preparation tool comprises the cassette 1 for medical examination and the embedding tray.

Description

  The present invention relates to a medical examination cassette and a paraffin block preparation tool used for preparation of a microscope specimen for medical examination, and more specifically, it is possible to prevent the occurrence of burrs and to mount an embedding tray at the bottom of the cassette body. The present invention relates to a medical examination cassette and a paraffin block making tool that are easy to do.

  As shown in FIGS. 16 and 17, this type of conventional medical examination cassette (hereinafter sometimes simply referred to as a cassette) includes a cassette body C1 made of a chemical-resistant synthetic resin and a lid C2. It becomes. The cassette body C1 is a rectangular container having an open top surface, and has a plurality of through holes C3 on the bottom surface, and is a plate-shaped recording portion that is inclined outwardly toward the bottom surface on the outer side of one side wall on the short side. C1a is provided. The lid C2 is a detachable plate-like body and has a large number of through holes C3 on the plate surface.

  In order to prepare a microscope specimen using the cassette C, first, as shown in FIG. 17, the collected specimen S is accommodated in the cassette body C1, the lid C2 is attached, and the subject is attached to the recording section C1a. Record a symbol or the like for identifying

  Subsequently, the specimen S is washed with water through the through-hole C3 of the lid C2, the moisture of the specimen S is removed with alcohol, the fat content of the specimen S is removed with xylene, and affinity with liquid paraffin described later is imparted. .

  Next, liquid paraffin P is put into a stainless steel embedding tray (hereinafter sometimes simply referred to as a tray) T as shown in FIG. 18, and the specimen S is taken out from the cassette body C1 and placed in the tray T. In the tray T, liquid paraffin is infiltrated into the specimen S in the tray T, and the specimen S is temporarily fixed. Subsequently, the cassette body C1 is placed on the stepped portion of the tray T, and liquid paraffin P is further poured onto the sample S until the bottom surface of the cassette body C1 is immersed in the liquid paraffin P (see FIG. 19).

  After the liquid paraffin P is solidified, the tray T is removed to obtain a paraffin block B in which the paraffin P embedded with the specimen S adheres to the bottom surface of the cassette body C1 (see FIG. 20).

  Next, although not shown, the paraffin block B is turned over and placed on the microtome, and the adapter installed on the microtome is engaged with the paraffin block B to fix the paraffin block B to the microtome. Subsequently, a portion in which the specimen S of paraffin P is embedded is sliced, and the obtained thin piece is stained and subjected to other predetermined processing to obtain a microscope specimen.

  However, when the paraffin block B is created by the above method, the paraffin swells on the horizontal frame portion T1 provided horizontally from the upper end portion of the tray T, and the paraffin is cooled and solidified in this state. It becomes a burr and remains in the paraffin block B. This burr b prevents the adapter from engaging with the paraffin block B when fixing the paraffin block B to the microtome, so it is necessary to scrape the burr with a cutter or the like, but the cooled and solidified paraffin is hard and difficult to cut. The deburring work is complicated.

  Therefore, a tray (see Patent Document 1) in which a narrow cassette support portion is formed at the boundary between the side wall portion and the locking wall has been proposed so that the deburring operation does not occur. Since the tray has a narrow cassette support portion, there is a problem that it is not always easy to mount the cassette on the tray. In order to solve this problem, a cassette support portion is formed large at the corner of the tray (see Patent Document 2), the cassette is sandwiched by a sandwiching plate inclined inward (see Patent Document 3), or a small claw portion. Improvements such as providing a cassette to prevent the cassette from sliding (see Patent Document 4) have been proposed. These techniques have the advantage that costs can be reduced because conventional cassettes can be used as they are.

JP 2008-145118 A JP 2008-145218 A JP 2008-180625 A JP 2009-042075 A

However, in spite of the improvement as described above, all of these trays are formed with a horizontal cassette support part, and paraffin is retained therein, so that the generation of burrs cannot be sufficiently prevented. The problem that it is difficult to mount the cassette on the tray has not been solved.
An object of the present invention is to provide a cassette that prevents the occurrence of burrs and can be easily mounted on a tray, and a paraffin block making tool using the cassette.

  A feature of the present invention for achieving the above object is a cassette for medical examination in which an embedding tray can be attached to the bottom rear surface, and a cassette body having a large number of through holes in a bottom portion of a rectangular container opened upward. The medical examination cassette includes a lid having a large number of through holes, and has a fitting portion provided at a position where the upper edge of the embedding tray abuts on the bottom rear surface of the cassette body.

  Another feature of the present invention includes the above-described medical examination cassette in which the fitting portion has a groove shape.

  According to still another aspect of the present invention, the fitting section includes the above-described cassette for medical examination in which both ends are linear grooves opened to the side of the cassette body.

  Still another feature of the present invention includes the above-described cassette for medical examination in which the fitting portion is provided so as to contact the entire upper edge portion of the embedding tray.

  Still another feature of the present invention is the above-described cassette for medical examination, characterized in that an extrusion hole penetrating from the upper surface or side surface of the cassette body to the fitting portion on the bottom surface is formed.

  Still another feature of the present invention is a paraffin block making tool comprising the above-described medical examination cassette and an embedding tray, wherein the embedding tray has at least an adapter for mounting the paraffin block on the microtome. The upper edge portion of the side that is in contact with the upper end portion of the medical examination cassette is attached to the bottom portion of the medical examination cassette. The paraffin block making tool that comes into contact with the contents.

  Still another feature of the present invention includes the above-described paraffin block making tool in which the upper edge portion is erected in the vertical direction.

  Still another feature of the present invention includes the paraffin block making tool described above in which the upper edge of the embedding tray is erected over the entire circumference.

  Still another feature of the present invention is that, in the edge portion of the embedding tray, a grip portion extending horizontally in the upper edge portion on the side where the adapter for attaching the paraffin block to the microtome does not contact the paraffin block The above-described paraffin block making tool is formed.

  In the medical examination cassette of the present invention, since the upper edge of the tray is fitted to the fitting portion of the cassette, the outflow of paraffin is prevented, so that the occurrence of burrs is prevented. Moreover, since the fitting part is provided in the bottom back surface of a cassette main body along the position where the edge part of an embedding tray contact | abuts, by fitting this fitting part and the upper edge part of an embedding tray, The embedding tray can be easily attached to the bottom of the cassette.

  Moreover, if the shape of the fitting portion is a groove shape, the groove-like fitting portion of the cassette and the upper edge portion of the tray are fitted, so that the paraffin can be more reliably prevented from flowing out.

  In addition, if the fitting part is a straight groove with both ends open to the side of the cassette body, even if the fitting part is clogged with paraffin, it can be clogged by tracing the inside of the fitting part with a pin or knife. Paraffin can be easily extruded and removed.

  If the fitting part is provided so as to be in contact with the entire upper edge part of the tray, there is no gap between the cassette and the tray where the paraffin leaks over the entire circumference, so that the generation of burrs is prevented more effectively. The

  If an extrusion hole that penetrates from the top or side surface of the cassette body to the fitting part on the bottom surface is drilled, when removing the tray from the paraffin block, an elongated bar-like member is inserted into the extrusion hole and the upper edge of the tray is pushed. The tray can be easily removed from the paraffin block.

  If the upper edge portion of the tray is erected in the vertical direction, the upper edge portion and the fitting portion of the cassette can be easily fitted, and workability is improved. In particular, when the shape of the fitting portion is a groove shape, the upper edge of the tray is fitted into the groove-like fitting portion, so that the outflow of paraffin can be more reliably prevented, and the generation of burrs is further effective. Is prevented.

  If the embedding tray is provided with a grip portion, the tray can be easily handled, so that workability is increased.

Fig.1 (a) is a side view which shows an example of the cassette for medical examinations of this invention, (b), (c) is the bottom view. FIG. 2 is a cross-sectional view of the cassette of FIG. FIG. 3 is a cross-sectional view and a main part enlarged view showing another example of the medical examination cassette. FIG. 4 is a cross-sectional view and an enlarged view of a main part showing another example of a cassette for medical examination. Fig.5 (a) is a side view which shows another example of the cassette for medical examination, (b) is the bottom view. FIG. 6A is a side view showing still another example of the medical examination cassette, and FIG. 6B is a bottom view thereof. Fig.7 (a) is a front view which shows an example of the embedding tray used with the cassette for medical examinations of this invention, (b) is the top view. FIG. 8 is a plan view showing another example of the embedding tray. FIG. 9 shows a paraffin block making tool including the medical examination cassette of FIGS. 1 and 2 and the embedding tray of FIG. FIG. 10 shows a paraffin block making tool comprising the medical examination cassette of FIG. 3 and the embedding tray of FIG. FIG. 11 shows a paraffin block making tool comprising the medical examination cassette of FIG. 4 and the embedding tray of FIG. FIG. 12A is a bottom view showing the cassette body in which the extrusion hole is formed, and FIG. 12B is a sectional view taken along the line BB. FIG. 13 is a schematic explanatory diagram for explaining a state in which an extrusion bar is inserted into the extrusion hole and the embedding tray is peeled off from the paraffin block. FIG. 14 is a schematic cross-sectional view showing another example of the cassette body in which the extrusion hole is formed. FIG. 15 shows a paraffin block making tool comprising the medical examination cassette of FIG. 5 and the embedding tray of FIG. FIG. 16 is a perspective view showing a conventional medical examination cassette. FIG. 17 is a cross-sectional view showing a state in which a specimen is put in a conventional medical examination cassette. FIG. 18 is a perspective view of an embedding tray used with a conventional medical examination cassette. FIG. 19 is a cross-sectional view showing a method for producing a paraffin block. FIG. 20 is a cross-sectional view showing the obtained paraffin block.

  The present invention is a medical examination cassette 1 in which an embedding tray 4 can be mounted on the back surface of a bottom portion 2b of a cassette body 2, and as shown in FIGS. 1 and 2, a large number of rectangular containers open upward are formed at the bottom portion. A cassette body 2 having a plurality of through holes 2a and a lid body 3 having a plurality of through holes 3a. A groove is formed on the back surface of the bottom 2b of the cassette body 2 at a position where the upper edge 4a of the embedding tray 4 abuts. It is characterized in that a fitting part 2c having a shape is provided. FIG. 1B shows an example in which the groove-like fitting portion 2c is provided around the portion of the bottom surface 2b of the cassette body 2 where the through hole 2a is provided. In FIG. It is an example extended to the bottom surface of the recording part 2d.

  In the present invention, the cassette body 2 is a rectangular container that opens upward, and has a large number of through holes 2a at the bottom, as shown in FIG. In this example, the shape of the through hole 2a is a square, but the shape is not particularly limited, and may be, for example, a circle, an ellipse, or a polygon.

The lid 3 according to the present invention is attached to the opening of the cassette body 2 and has a large number of through holes 3 a as with the bottom 2 b of the cassette body 2.
In this example, the lid 3 is rectangular and has a structure in which a rib is provided on the lower side. However, the shape of the lid 3 and the mounting structure to the cassette body 2 are not particularly limited, and this kind of All shapes and structures that can be used in the medical examination cassette 1 can be applied to the present invention.

  FIGS. 3 and 4 show other examples of the cassette of the present invention. In the cassette of FIG. 3, a stepped fitting portion 2c is formed by cutting out the outer edge portion of the bottom portion 2b of the cassette body 2. FIG. Further, in the cassette of FIG. 4, a step-like fitting portion 2c is formed by leaving the outer edge portion and cutting out the inner portion.

  FIG. 5 shows another example of the cassette of the present invention, in which fitting portions 2c are formed on two opposite sides (short sides in the figure) of the bottom 2b of the cassette body 2. FIG. When attaching the paraffin block to the microtome, the sides where the adapter contacts the microtome are two opposite sides (short sides in the figure), so it is only necessary to prevent the occurrence of burrs on these two sides. This is an example in which a fitting portion 2c is provided.

  In the example shown in FIG. 5, the fitting portion 2 c is a linear groove whose both ends are opened to the side of the cassette body 2. For this reason, even when the fitting part 2c is clogged with paraffin or dust, it is possible to easily scrape and remove the paraffin or dust in the fitting part 2c by tracing the inside of the fitting part 2c with a knife or a thin plate. it can.

  Furthermore, in the example shown in FIG. 6, the fitting portion 2 c is formed by combining four linear grooves whose both ends are opened to the side of the cassette body 2. If the medical cassette provided with such a fitting part 2c is used, the effect which can prevent generation | occurrence | production of a burr | flash on all the sides, and the effect which makes the inside of a fitting part easy to clean can be compatible.

  The paraffin block making tool of the present invention comprises the cassette 1 and the embedding tray 4.

FIG. 7 shows an example of the embedding tray 4 used with the cassette of the present invention. In this example, the vicinity of the upper edge portion 4a of the embedding tray 4 is erected in the vertical direction so that the fitting portion 2c formed on the bottom portion 2b of the cassette body 2 can be easily fitted.
FIG. 8 shows another example of the embedding tray 4, and a gripping portion 4 b is formed in the horizontal direction at the center of the upper edge of the two opposing sides (long sides in the figure) of the embedding tray 4. The two opposite sides in this case are the sides where the adapter does not contact the microtome, that is, the two sides that do not hinder the occurrence of burrs.

  FIG. 9 shows a paraffin block making tool including the cassette 1 of FIGS. 1 (a) and 1 (b) and FIG. 2 and the embedding tray 4 of FIG. In the preparation tool of this example, the groove-like fitting portion 2c provided on the bottom portion 2b of the cassette body 2 and the upper edge portion 4a of the embedding tray 4 are fitted and fitted, and the outflow of paraffin is prevented. Is prevented from occurring. Moreover, since the recessed part 2c and the upper edge part 4a should just be inserted and fitted, mounting | wearing with the cassette 1 and the embedding tray 4 is easy. In this case, the groove-like fitting portion 2c is preferably tapered so as to expand toward the inlet in order to facilitate the fitting and fitting of the upper edge portion 4a of the embedding tray 4. Moreover, it is preferable that the upper edge 4a of the embedding tray 4 is also designed to be tapered so as to be reduced toward the tip, so as to be in close contact with the tapered groove-like fitting portion 2c. When the groove-like fitting portion 2c is fitted and fitted with the upper edge portion 4a of the embedding tray 4, contact between the three surfaces prevents paraffin from flowing out.

  FIG. 10 shows a paraffin block making tool comprising the cassette 1 of FIG. 3 and the embedding tray 4 of FIG. In the preparation tool of this example, the step-shaped fitting portion 2c provided on the bottom 2b of the cassette body 2 and the upper edge portion 4a of the embedding tray 4 are fitted, and the outflow of paraffin is stopped, and burrs are generated. Is prevented. Moreover, since the step-shaped fitting part 2c and the upper edge part 4a should just be fitted, attachment with the cassette 1 and the embedding tray 4 is easy. In the case of the step-shaped fitting portion 2c, when it is fitted to the upper edge portion 4a of the embedding tray 4, contact with two surfaces prevents paraffin from flowing out.

  FIG. 11 shows a paraffin block creating tool comprising the cassette 1 of FIG. 4 and the embedding tray 4 of FIG. In the preparation tool of this example, the stepped fitting portion 2c provided on the bottom portion 2b of the cassette body 2 and the upper edge portion 4a of the embedding tray 4 are fitted, similarly to the paraffin block preparation tool of FIG. The contact between the two surfaces prevents the paraffin from flowing out and prevents the generation of burrs. Moreover, since the step-shaped fitting part 2c and the upper edge part 4a should just be fitted, attachment with the cassette 1 and the embedding tray 4 is easy.

By the way, when the embedding tray 4 in which the entire upper edge portion 4a as shown in FIG. 7 is vertically erected is used, it is excellent in preventing the occurrence of burrs by preventing the paraffin from flowing out. It may be difficult to remove the tray 4 from the paraffin block B.
In such a case, as shown in FIG. 12, a medical device in which an extrusion hole 2e penetrating from the upper surface or side surface (upper surface in the example shown in FIG. 12) of the cassette body 2 to the fitting portion 2c on the bottom surface is formed. The inspection cassette 1 may be used. For example, as shown in FIG. 13, if the extrusion bar 2f is inserted into the extrusion hole 2e and the upper edge 4a of the embedding tray 4 is pushed by the extrusion bar 2f, the embedding tray 4 can be easily removed from the paraffin block B. Can be removed.

  The number of extrusion holes 2e is not particularly limited, and may be provided not only on one side but also on two, three sides, or on all four sides. Further, the pushing bar 2f can be provided with a horizontal pressing head at the tip so as to be easily pressed. In this case, after inserting the extruding bar 2f into the extruding hole 2e, the top and bottom of the extruding bar 2f are turned over and pressed against the surface of a desk, work table, etc. The buried tray 4 can be removed with one touch and workability can be improved. Further, a female screw is engraved inside the extrusion hole 2e, a male screw is engraved on the outer periphery of the extrusion bar 2f, and the extrusion bar 2f is screwed into the extrusion hole 2e so as to enter from the paraffin block B. It is also possible to remove the buried tray 4.

  In the example shown in FIGS. 12 and 13, the extrusion hole 2e is formed perpendicularly to the cassette body, but can also be formed in an oblique direction as shown in FIG. When drilling in an oblique direction, it is preferable to make the angle closer to the vertical than the inclination angle of the side wall of the embedding tray 4. In this case, as shown in FIG. 14, the extrusion hole 2 e may be a hole penetrating from the side surface to the bottom surface of the cassette body 2.

FIG. 15 shows a paraffin block making tool comprising the cassette 1 of FIG. 5 and the embedding tray 4 of FIG. In the preparation tool of this example, the groove-like fitting portion 2c provided on the bottom portion 2b of the cassette body 2 and the upper edge portion 4a of the embedding tray 4 are fitted and fitted, and the outflow of paraffin is prevented. Is prevented from occurring. Moreover, since the groove-shaped fitting part 2c and the upper edge part 4a should just be inserted and fitted, attachment with the cassette 1 and the embedding tray 4 is easy.
In this example, as described above, the side where the adapter is in contact with the microtome is the opposite short side (FIG. 15 (a)), and therefore the long side where the adapter is not in contact with the microtome may be burred. Therefore, the grip portion 4 b is provided in the horizontal direction from the upper edge portion of the embedding tray 4.

  In the present invention, the material of the cassette body 2 and the lid 3 is not particularly limited as long as it is a hard member having chemical resistance, but is preferably made of resin from the viewpoint of moldability and lightness. Examples of synthetic resins that can be used in the present invention include POM resin (polyacetal resin), ABS resin (acrylonitrile-butadiene-styrene copolymer resin), AAS resin (acrylonitrile / acrylic rubber / styrene resin), AES resin (acrylonitrile / ethylene). Propylene rubber / styrene resin), AS resin (acrylonitrile / styrene resin), PS resin (polystyrene resin), PMMA resin (polymethyl methacrylate resin), PVC resin (polyvinylidene chloride resin), MS resin (methyl methacrylate / styrene resin) , PP resin (polypropylene resin), PE resin (polyethylene resin), PBT resin (polybutylene terephthalate resin), PC resin (polycarbonate resin), and the like. Polylactic acid resin, polybutylene succine DOO, polyamide 11, biodegradable plastics and biomass plastics such as polyhydroxybutyric acid may also be used.

  In the present invention, the material of the embedding tray 4 is not particularly limited, and any material that can be used for this type of embedding tray can be used. Specifically, metals are preferable in terms of excellent heat dissipation, among which stainless steel, iron, copper, aluminum and the like are more preferable in terms of a good balance between cost and strength, and stainless steel is particularly preferable in terms of excellent durability. .

  As described above, according to the medical examination cassette and paraffin block preparation tool of the present invention, it is possible to prevent the occurrence of burrs and to easily mount the embedding tray on the bottom of the cassette body. It is highly efficient and extremely useful as a medical examination cassette and paraffin block preparation tool.

DESCRIPTION OF SYMBOLS 1 Medical test | inspection cassette 2 Cassette main body 2a Through-hole 2b Bottom part 2c Fitting part 2d Recording part 2e Extrusion hole 2f Extrusion stick 3 Lid 3a Through-hole 4 Embedding tray 4a Upper edge part 4b Gripping part S Sample C Conventional medical examination Cassette C1 Cassette body C1a Recording unit C2 Lid C3 Through hole T Conventional embedding tray T1 Frame P Paraffin B Paraffin block b Burr

Claims (9)

A medical test cassette capable of mounting an embedding tray on the bottom back surface,
Including a cassette body having a large number of through holes at the bottom in a rectangular container opened upward, and a lid having a large number of through holes,
A cassette for medical examination, wherein a fitting portion is provided at a position where an upper edge portion of the embedding tray comes into contact with a bottom rear surface of the cassette body.   The medical examination cassette according to claim 1, wherein the fitting portion has a groove shape.   The medical examination cassette according to claim 2, wherein the fitting portion is a linear groove whose both ends are opened to the side of the cassette body.   The medical examination cassette according to claim 1 or 3, wherein the fitting portion is provided so as to contact the entire upper edge portion of the embedding tray.   5. The medical examination cassette according to claim 1, wherein an extrusion hole penetrating from an upper surface or a side surface of the cassette body to a fitting portion on the bottom surface is formed. A paraffin block creating tool comprising the medical examination cassette according to any one of claims 1 to 5 and an embedding tray,
The embedding tray is a shape in which an upper edge portion is erected on the side where the adapter for attaching the paraffin block to the microtome is in contact with the paraffin block,
The paraffin block making tool, wherein the upper edge portion comes into contact with a fitting portion provided at the bottom of the medical examination cassette when the medical examination cassette is attached to the bottom.   The paraffin block making tool according to claim 6, wherein the upper edge portion is erected in the vertical direction.   The paraffin block creation tool according to claim 6 or 7, wherein the upper edge portion of the embedding tray is erected over the entire circumference.   Of the edge of the embedding tray, the adapter for mounting the paraffin block to the microtome is formed on the side where the adapter does not contact the paraffin block, and a gripping part extending in the horizontal direction is formed on the upper edge. The paraffin block making tool according to any one of claims 6 to 8.

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