JP2015105842A5 - - Google Patents

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Publication number
JP2015105842A5
JP2015105842A5 JP2013246906A JP2013246906A JP2015105842A5 JP 2015105842 A5 JP2015105842 A5 JP 2015105842A5 JP 2013246906 A JP2013246906 A JP 2013246906A JP 2013246906 A JP2013246906 A JP 2013246906A JP 2015105842 A5 JP2015105842 A5 JP 2015105842A5
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JP
Japan
Prior art keywords
container
amount
buffer solution
hepatocytes
drug
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2013246906A
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English (en)
Japanese (ja)
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JP2015105842A (ja
JP6087264B2 (ja
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Application filed filed Critical
Priority claimed from JP2013246906A external-priority patent/JP6087264B2/ja
Priority to JP2013246906A priority Critical patent/JP6087264B2/ja
Priority to CN201710860736.XA priority patent/CN107513550B/zh
Priority to CN201710862144.1A priority patent/CN107677779B/zh
Priority to US14/914,278 priority patent/US9880153B2/en
Priority to CN201480040060.4A priority patent/CN105378053B/zh
Priority to EP14866627.4A priority patent/EP3023489B1/en
Priority to PCT/JP2014/081135 priority patent/WO2015080106A1/ja
Priority to EP20154632.2A priority patent/EP3712245B1/en
Priority to EP17186423.4A priority patent/EP3272852B1/en
Publication of JP2015105842A publication Critical patent/JP2015105842A/ja
Publication of JP2015105842A5 publication Critical patent/JP2015105842A5/ja
Publication of JP6087264B2 publication Critical patent/JP6087264B2/ja
Application granted granted Critical
Priority to US15/847,092 priority patent/US10684276B2/en
Priority to US16/856,459 priority patent/US11789013B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013246906A 2013-11-29 2013-11-29 成分分析装置、薬効分析装置、及び分析方法 Active JP6087264B2 (ja)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP2013246906A JP6087264B2 (ja) 2013-11-29 2013-11-29 成分分析装置、薬効分析装置、及び分析方法
PCT/JP2014/081135 WO2015080106A1 (ja) 2013-11-29 2014-11-26 成分分析装置、薬効分析装置、及び分析方法
EP17186423.4A EP3272852B1 (en) 2013-11-29 2014-11-26 Componential analyzer, drug efficacy analyzer, and analysis method
US14/914,278 US9880153B2 (en) 2013-11-29 2014-11-26 Componential analyzer, drug efficacy analyzer, and analysis method
CN201480040060.4A CN105378053B (zh) 2013-11-29 2014-11-26 成分分析装置、药效分析装置和分析方法
EP14866627.4A EP3023489B1 (en) 2013-11-29 2014-11-26 Componential analyzer, drug efficacy analyzer, and analysis method
CN201710860736.XA CN107513550B (zh) 2013-11-29 2014-11-26 成分分析方法
EP20154632.2A EP3712245B1 (en) 2013-11-29 2014-11-26 Componential and drug efficacy analysis method
CN201710862144.1A CN107677779B (zh) 2013-11-29 2014-11-26 成分分析装置、药效分析装置和分析方法
US15/847,092 US10684276B2 (en) 2013-11-29 2017-12-19 Componential analyzer, drug efficacy analyzer, and analysis method
US16/856,459 US11789013B2 (en) 2013-11-29 2020-04-23 Componential analyzer, drug efficacy analyzer, and analysis method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013246906A JP6087264B2 (ja) 2013-11-29 2013-11-29 成分分析装置、薬効分析装置、及び分析方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017014985A Division JP6282362B2 (ja) 2017-01-31 2017-01-31 成分分析装置、薬効分析装置、及び分析方法

Publications (3)

Publication Number Publication Date
JP2015105842A JP2015105842A (ja) 2015-06-08
JP2015105842A5 true JP2015105842A5 (enExample) 2016-10-06
JP6087264B2 JP6087264B2 (ja) 2017-03-01

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ID=53199046

Family Applications (1)

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JP2013246906A Active JP6087264B2 (ja) 2013-11-29 2013-11-29 成分分析装置、薬効分析装置、及び分析方法

Country Status (5)

Country Link
US (3) US9880153B2 (enExample)
EP (3) EP3712245B1 (enExample)
JP (1) JP6087264B2 (enExample)
CN (3) CN107513550B (enExample)
WO (1) WO2015080106A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6087264B2 (ja) 2013-11-29 2017-03-01 株式会社日立ハイテクノロジーズ 成分分析装置、薬効分析装置、及び分析方法
JP6758026B2 (ja) * 2015-04-17 2020-09-23 株式会社日立ハイテク 成分分析装置、薬剤成分分析装置、成分分析方法及び薬剤成分分析方法
JP6582070B2 (ja) * 2018-01-22 2019-09-25 株式会社日立ハイテクノロジーズ 分析方法
CN113396225A (zh) * 2019-02-26 2021-09-14 株式会社日立高新技术 细胞内的化合物的动态分析法
WO2021014519A1 (ja) * 2019-07-22 2021-01-28 株式会社日立ハイテク 試薬キット
WO2023084648A1 (ja) * 2021-11-10 2023-05-19 株式会社日立ハイテク 薬剤相互作用解析方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5255976A (en) 1992-07-10 1993-10-26 Vertex Pharmaceuticals Incorporated Temperature gradient calorimeter
WO1994012662A1 (en) 1992-11-25 1994-06-09 Merck & Co., Inc. Hepatic model
CA2130013C (en) * 1993-09-10 1999-03-30 Rolf Moser Apparatus for automatic performance of temperature cycles
US6277655B1 (en) * 1994-10-13 2001-08-21 Solvo Biotechnology Assay and reagent kit for evaluation of multi-drug resistance in cells
US6022733A (en) * 1997-12-02 2000-02-08 Tam; Yun K. Simulated biological dissolution and absorption system
US7498164B2 (en) * 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
EP2112511B1 (en) * 1999-03-17 2012-01-18 University Of North Carolina At Chapel Hill Method of screening candidate compounds for susceptibility to biliary excretion
US7601494B2 (en) 1999-03-17 2009-10-13 The University Of North Carolina At Chapel Hill Method of screening candidate compounds for susceptibility to biliary excretion
AR035231A1 (es) * 2002-03-11 2004-05-05 Ypf S A Un equipo para analizar el crecimiento de microorganismos y procedimiento para cuantificar la concentracion de microorganismos
US20070184548A1 (en) * 2002-12-23 2007-08-09 Lim Hi Tan Device for carrying out chemical or biological reactions
CN101977643A (zh) 2008-03-24 2011-02-16 奥林巴斯株式会社 药剂投放装置
WO2010079602A1 (ja) * 2009-01-08 2010-07-15 株式会社日立製作所 動物肝細胞の培養方法
US8906644B2 (en) 2009-08-26 2014-12-09 The University Of Tokyo Method for culture of hepatocytes
US8945865B2 (en) 2011-03-10 2015-02-03 Eisai R&D Management Co., Ltd. Method for screening for compound capable of enhancing or inhibiting OATP1B1 transport activity, and method for determining expression level of OATP1B1
US20130164335A1 (en) 2011-12-27 2013-06-27 National Health Research Institutes Methods and compositions for cellular drug release
JP6087264B2 (ja) 2013-11-29 2017-03-01 株式会社日立ハイテクノロジーズ 成分分析装置、薬効分析装置、及び分析方法

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