JP2014533502A5 - - Google Patents
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- Publication number
- JP2014533502A5 JP2014533502A5 JP2014542300A JP2014542300A JP2014533502A5 JP 2014533502 A5 JP2014533502 A5 JP 2014533502A5 JP 2014542300 A JP2014542300 A JP 2014542300A JP 2014542300 A JP2014542300 A JP 2014542300A JP 2014533502 A5 JP2014533502 A5 JP 2014533502A5
- Authority
- JP
- Japan
- Prior art keywords
- probe
- different
- capture
- target nucleic
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000523 sample Substances 0.000 claims 43
- 238000000034 method Methods 0.000 claims 18
- 150000007523 nucleic acids Chemical group 0.000 claims 13
- 239000012634 fragment Substances 0.000 claims 11
- 230000003321 amplification Effects 0.000 claims 8
- 238000003199 nucleic acid amplification method Methods 0.000 claims 8
- 239000000758 substrate Substances 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 230000000295 complement effect Effects 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000007850 fluorescent dye Substances 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 101710163270 Nuclease Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000010791 quenching Methods 0.000 claims 1
- 230000000171 quenching effect Effects 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161561198P | 2011-11-17 | 2011-11-17 | |
| US61/561,198 | 2011-11-17 | ||
| PCT/US2012/025699 WO2012112925A2 (en) | 2011-02-18 | 2012-02-17 | Quantitative, highly multiplexed detection of nucleic acids |
| US13/399,872 US20120214686A1 (en) | 2011-02-18 | 2012-02-17 | Quantitative, Highly Multiplexed Detection of Nucleic Acids |
| USPCT/US2012/025699 | 2012-02-17 | ||
| US13/399,872 | 2012-02-17 | ||
| PCT/US2012/051236 WO2013074163A1 (en) | 2011-11-17 | 2012-08-16 | Quantitative, highly multiplexed detection of nucleic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014533502A JP2014533502A (ja) | 2014-12-15 |
| JP2014533502A5 true JP2014533502A5 (cg-RX-API-DMAC7.html) | 2015-10-15 |
Family
ID=48430026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014542300A Pending JP2014533502A (ja) | 2011-11-17 | 2012-08-16 | 核酸の定量的な高多重化検出 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2780479A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2014533502A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140094007A (cg-RX-API-DMAC7.html) |
| CN (1) | CN104093857A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012337389A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014011937A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2855953A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1199746A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL232586A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX338076B (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201402341QA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013074163A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6050555B2 (ja) * | 2013-07-15 | 2016-12-21 | シージーン アイエヌシー | Ｐｔｏの切断及び延長−依存的固定化オリゴヌクレオチドハイブリダイゼーションを用いたターゲット核酸配列の検出 |
| EP3283501B1 (en) * | 2015-04-16 | 2023-01-04 | William Marsh Rice University | Stoichiometric tuning of nucleic acid hybridization probes by auxiliary oligonucleotide species |
| CN110016500A (zh) * | 2018-01-10 | 2019-07-16 | 深圳闪量科技有限公司 | 表面探针定量pcr方法 |
| CN115210760B (zh) * | 2019-11-21 | 2023-08-01 | 10X基因组学有限公司 | 分析物的空间分析 |
| CN111808989A (zh) * | 2020-06-18 | 2020-10-23 | 重庆浦洛通基因医学研究院有限公司 | 一种冠状病毒/流感病毒/鼻病毒核酸联合检测试剂盒及使用方法 |
| EP4442838A3 (en) * | 2020-10-15 | 2024-12-25 | Genentech, Inc. | Multiplexed target-binding candidate screening analysis |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422253A (en) * | 1992-12-07 | 1995-06-06 | Wisconsin Alumni Research Foundation | Method of site specific nucleic acid cleavage |
| US6350580B1 (en) * | 2000-10-11 | 2002-02-26 | Stratagene | Methods for detection of a target nucleic acid using a probe comprising secondary structure |
| US7189508B2 (en) * | 2001-07-17 | 2007-03-13 | Stratagene California | Methods for detection of a target nucleic acid by capture using multi-subunit probes |
| US20070092880A1 (en) * | 2003-07-16 | 2007-04-26 | Crothers Donald M | Invasive cleavage reaction with electrochemical readout |
| WO2005068660A1 (en) * | 2003-12-19 | 2005-07-28 | Beckman Coulter, Inc. | Solid-phase multiplexed invader assay |
| US9115389B2 (en) * | 2006-06-30 | 2015-08-25 | Rosetta Genomics Ltd. | Method for detecting a target nucleic acid comprising two portions using probes having a first portion complementary to the first portion of the target nucleic acid and a second portion substantially complementary to the second portion of the target nucleic acid |
| EP2118310B1 (en) * | 2006-12-29 | 2013-03-06 | Applied Biosystems, LLC | Systems and methods for detecting nucleic acids |
| EP2077336A1 (en) * | 2007-12-19 | 2009-07-08 | Koninklijke Philips Electronics N.V. | Device and method for parallel quantitative analysis of multiple nucleic acids |
| BRPI0916143A2 (pt) * | 2008-11-21 | 2015-11-03 | Koninkl Philips Electronics Nv | "método para monitorar a multiplicação de um ou mais ácidos nucleicos visados" |
-
2012
- 2012-08-16 SG SG11201402341QA patent/SG11201402341QA/en unknown
- 2012-08-16 HK HK15100214.3A patent/HK1199746A1/xx unknown
- 2012-08-16 EP EP12849697.3A patent/EP2780479A4/en not_active Withdrawn
- 2012-08-16 WO PCT/US2012/051236 patent/WO2013074163A1/en not_active Ceased
- 2012-08-16 MX MX2014005912A patent/MX338076B/es active IP Right Grant
- 2012-08-16 CN CN201280067273.7A patent/CN104093857A/zh active Pending
- 2012-08-16 KR KR1020147016411A patent/KR20140094007A/ko not_active Withdrawn
- 2012-08-16 BR BR112014011937A patent/BR112014011937A2/pt not_active IP Right Cessation
- 2012-08-16 CA CA2855953A patent/CA2855953A1/en not_active Abandoned
- 2012-08-16 JP JP2014542300A patent/JP2014533502A/ja active Pending
- 2012-08-16 AU AU2012337389A patent/AU2012337389A1/en not_active Abandoned
-
2014
- 2014-05-13 IL IL232586A patent/IL232586A0/en unknown