JP2014533289A5 - - Google Patents

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JP2014533289A5
JP2014533289A5 JP2014541421A JP2014541421A JP2014533289A5 JP 2014533289 A5 JP2014533289 A5 JP 2014533289A5 JP 2014541421 A JP2014541421 A JP 2014541421A JP 2014541421 A JP2014541421 A JP 2014541421A JP 2014533289 A5 JP2014533289 A5 JP 2014533289A5
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cell
rpe cells
item
cells
rpe
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JP6506023B2 (ja
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JP2014541421A 2011-11-14 2012-11-14 ヒトｒｐｅ細胞医薬品およびその使用 Active JP6506023B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161559521P 2011-11-14 2011-11-14
US61/559,521 2011-11-14
US201261589741P 2012-01-23 2012-01-23
US61/589,741 2012-01-23
US201261724047P 2012-11-08 2012-11-08
US61/724,047 2012-11-08
PCT/US2012/065091 WO2013074681A1 (en) 2011-11-14 2012-11-14 Pharmaceutical preparations of human rpe cells and uses thereof

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JP2017183914A Division JP6563996B2 (ja) 2011-11-14 2017-09-25 ヒトｒｐｅ細胞医薬品およびその使用

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JP2014533289A JP2014533289A (ja) 2014-12-11
JP2014533289A5 true JP2014533289A5 (enExample) 2016-01-07
JP6506023B2 JP6506023B2 (ja) 2019-04-24

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JP2014541421A Active JP6506023B2 (ja) 2011-11-14 2012-11-14 ヒトｒｐｅ細胞医薬品およびその使用
JP2017183914A Active JP6563996B2 (ja) 2011-11-14 2017-09-25 ヒトｒｐｅ細胞医薬品およびその使用
JP2019098508A Active JP6899865B2 (ja) 2011-11-14 2019-05-27 ヒトｒｐｅ細胞医薬品およびその使用
JP2021049493A Active JP7081016B2 (ja) 2011-11-14 2021-03-24 ヒトｒｐｅ細胞医薬品およびその使用
JP2022084915A Active JP7404441B2 (ja) 2011-11-14 2022-05-25 ヒトｒｐｅ細胞医薬品およびその使用
JP2023209915A Active JP7716463B2 (ja) 2011-11-14 2023-12-13 ヒトｒｐｅ細胞医薬品およびその使用
JP2025120956A Pending JP2025161815A (ja) 2011-11-14 2025-07-18 ヒトｒｐｅ細胞医薬品およびその使用

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JP2017183914A Active JP6563996B2 (ja) 2011-11-14 2017-09-25 ヒトｒｐｅ細胞医薬品およびその使用
JP2019098508A Active JP6899865B2 (ja) 2011-11-14 2019-05-27 ヒトｒｐｅ細胞医薬品およびその使用
JP2021049493A Active JP7081016B2 (ja) 2011-11-14 2021-03-24 ヒトｒｐｅ細胞医薬品およびその使用
JP2022084915A Active JP7404441B2 (ja) 2011-11-14 2022-05-25 ヒトｒｐｅ細胞医薬品およびその使用
JP2023209915A Active JP7716463B2 (ja) 2011-11-14 2023-12-13 ヒトｒｐｅ細胞医薬品およびその使用
JP2025120956A Pending JP2025161815A (ja) 2011-11-14 2025-07-18 ヒトｒｐｅ細胞医薬品およびその使用

Country Status (23)

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US (4) US20130195806A1 (enExample)
EP (2) EP3563860A1 (enExample)
JP (7) JP6506023B2 (enExample)
KR (1) KR102054904B1 (enExample)
CN (2) CN104080464A (enExample)
AU (5) AU2012340020A1 (enExample)
CA (2) CA2855941A1 (enExample)
CY (1) CY1121819T1 (enExample)
DK (1) DK2780022T4 (enExample)
ES (1) ES2734453T3 (enExample)
FI (1) FI2780022T4 (enExample)
GB (1) GB2496969A (enExample)
HK (1) HK1202456A1 (enExample)
HR (1) HRP20191110T1 (enExample)
HU (1) HUE044778T2 (enExample)
IL (5) IL287381B2 (enExample)
LT (1) LT2780022T (enExample)
PL (1) PL2780022T3 (enExample)
PT (1) PT2780022T (enExample)
RS (1) RS59050B1 (enExample)
SI (1) SI2780022T1 (enExample)
TW (5) TWI785403B (enExample)
WO (1) WO2013074681A1 (enExample)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
AU2005207042B2 (en) * 2004-01-23 2010-09-09 President And Fellows Of Harvard College Improved modalities for the treatment of degenerative diseases of the retina
CN104946591A (zh) 2007-10-12 2015-09-30 奥卡塔治疗公司 制备rpe 细胞和rpe 细胞的组合物的改良方法
EP2501802A4 (en) 2009-11-17 2013-08-21 Advanced Cell Tech Inc METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS
US10852069B2 (en) 2010-05-04 2020-12-01 Fractal Heatsink Technologies, LLC System and method for maintaining efficiency of a fractal heat sink
AU2011280878B2 (en) 2010-07-23 2016-06-16 Astellas Institute For Regenerative Medicine Methods for detection of rare subpopulations of cells and highly purified compositions of cells
CN103827303B (zh) 2011-09-26 2021-10-22 普瑞阿那利提克斯有限公司 细胞外核酸的稳定化和分离
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
US20140227688A1 (en) 2011-09-26 2014-08-14 Qiagen Gmbh Stabilisation and isolation of extracellular nucleic acids
IL287381B2 (en) * 2011-11-14 2024-04-01 Astellas Inst For Regenerative Medicine Pharmaceutical preparations of human rpe cells and uses thereof
EP2900834B1 (en) 2012-09-25 2016-11-09 Qiagen GmbH Stabilisation of biological samples
EP2951290B1 (en) 2013-02-01 2017-11-29 The United States of America, as represented by The Secretary, Department of Health and Human Services Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
WO2014146780A1 (en) 2013-03-18 2014-09-25 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
EP2976424B1 (en) 2013-03-18 2018-10-03 Qiagen GmbH Stabilisation of biological samples
JP6470286B2 (ja) 2013-11-27 2019-02-13 京都府公立大学法人 ラミニンの角膜内皮細胞培養への応用
BR112016012129A8 (pt) 2013-12-11 2020-05-12 Pfizer Ltd métodos para produção, expansão e purificação de células epiteliais do pigmento da retina, composição farmacêutica e uso das células
EP2898896A1 (en) * 2014-01-22 2015-07-29 Université Pierre et Marie Curie (Paris 6) Agents for use in the treatment of retinal inflammation
CN106102766A (zh) * 2014-01-22 2016-11-09 皮埃尔与玛丽·居里大学 - 巴黎第六大学 用于治疗视网膜炎症的试剂
EP3119197A1 (en) * 2014-03-18 2017-01-25 Qiagen GmbH Stabilization and isolation of extracellular nucleic acids
WO2015175504A1 (en) * 2014-05-12 2015-11-19 The Johns Hopkins University Differentiation of human pluripotent stem cells into retinal pigment epithelium using hif1 inhibitors
WO2015175783A1 (en) * 2014-05-15 2015-11-19 International Stem Cell Corporation Chemical differentiation of pluripotentstem cells into retinal epithelial cells
WO2015173425A1 (en) 2014-05-16 2015-11-19 Koninklijke Nederlandse Akademie Van Wetenschappen Improved culture method for organoids
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
US20160095307A1 (en) 2014-10-07 2016-04-07 NuTech Medical, Inc. Method and composition for hypothermic storage of placental tissue
KR20210013299A (ko) 2014-10-17 2021-02-03 코디악 사이언시스 인코포레이티드 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트
BR112017008805A2 (pt) * 2014-10-31 2017-12-19 Kyoto Prefectural Public Univ Corp tratamento de córnea usando laminina
US11918630B2 (en) * 2014-10-31 2024-03-05 Kyoto Prefectural Public University Corporation Treatment of retina and nerve using laminin
JP6734853B2 (ja) * 2014-12-18 2020-08-05 ソルボンヌ・ユニヴェルシテＳｏｒｂｏｎｎｅ Ｕｎｉｖｅｒｓｉｔｅ 網膜変性処置のためのｏｔｘ２過剰発現トランスジェニック網膜色素上皮細胞
KR102514912B1 (ko) * 2014-12-30 2023-03-27 셀 큐어 뉴로사이언시스 리미티드 망막 질환의 치료 방법
JP2018502575A (ja) 2014-12-30 2018-02-01 セル キュア ニューロサイエンシズ リミテッド 網膜色素上皮細胞集団の評価法
IL305070B2 (en) 2014-12-30 2025-11-01 Cell Cure Neurosciences Ltd Rpe cell populations and methods of generating same
ES2980659T3 (es) * 2015-03-23 2024-10-02 Astellas Inst For Regenerative Medicine Ensayos mejorados de potencia de células de epitelio pigmentario retiniano (EPR) humano y progenitores de fotorreceptores
CN105013010B (zh) * 2015-07-07 2018-01-12 中山大学中山眼科中心 一种辅助iPS‑RPE移植的层粘连蛋白膜
DK3331994T3 (da) 2015-08-05 2022-11-21 Cell Cure Neurosciences Ltd Fremstilling af retinale pigmentepitelceller
SG10201913250SA (en) 2015-08-18 2020-03-30 Astellas Inst For Regenerative Medicine Clinical formulations
CA2997763A1 (en) * 2015-09-08 2017-03-16 Cellular Dynamics International, Inc. Macs-based purification of stem cell-derived retinal pigment epithelium
EP3377645B1 (en) 2015-11-20 2023-10-04 Qiagen GmbH Method of preparing sterilized compositions for stabilization of extracellular nucleic acids
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
GB201603569D0 (en) 2016-03-01 2016-04-13 Koninklijke Nederlandse Akademie Van Wetenschappen Improved differentiation method
CN106420809B (zh) * 2016-08-31 2017-08-08 浙江济民制药股份有限公司 一种眼科手术灌注液
US12215349B2 (en) * 2016-12-13 2025-02-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of preparing an isolated or purified population of thymic emigrant cells and methods of treatment using same
US20200087390A1 (en) 2016-12-21 2020-03-19 Amgen Inc. Anti-tnf alpha antibody formulations
US11076984B2 (en) * 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
CA3056653A1 (en) * 2017-03-16 2018-09-20 Lineage Cell Therapeutics, Inc. Methods for the treatment of retinal diseases
CA3061900A1 (en) * 2017-05-01 2018-11-08 The Board Of Supervisors Of Louisiana State University And Agriculturaand Mechanical College Compositions and methods for treating ocular pathologies
GB201721615D0 (en) 2017-12-21 2018-02-07 Koninklijke Nederlandse Akademie Van Wetenschappen Immune cell organoid co-cultures
CN111741735A (zh) * 2017-12-29 2020-10-02 细胞治疗神经科学有限公司 视网膜色素上皮细胞组合物
EP4371535A3 (en) 2018-02-22 2024-08-14 Alcon Inc. Ocular implant
US12071476B2 (en) * 2018-03-02 2024-08-27 Kodiak Sciences Inc. IL-6 antibodies and fusion constructs and conjugates thereof
IL282791B2 (en) * 2018-11-19 2026-03-01 Us Health Biodegradable tissue replacement implant and its use
GB201819224D0 (en) 2018-11-26 2019-01-09 Koninklijke Nederlandse Akademie Van Wetenschappen Hepatocyte expansion methods
JP7590968B2 (ja) * 2018-12-05 2024-11-27 アビオナ・セラピュ―ティクス・インコーポレイテッド 遺伝子送達のための組み換えアデノ随伴ウイルスベクター
EP3976765A1 (en) * 2019-05-28 2022-04-06 F. Hoffmann-La Roche AG Method to generate monocytic progenitor cells
MA54325A (fr) 2019-06-05 2022-05-11 Regeneron Pharma Dispositifs et procédés pour l'administration précise de doses
KR102198942B1 (ko) * 2019-07-02 2021-01-05 의료법인 성광의료재단 Pedf를 발현하거나 모세포에 비하여 pedf를 과발현하도록 유전적으로 조작된 중간엽 줄기세포
WO2021034784A1 (en) 2019-08-16 2021-02-25 Poltorak Technologies, LLC Device and method for medical diagnostics
AU2020364071A1 (en) 2019-10-10 2022-05-26 Kodiak Sciences Inc. Methods of treating an eye disorder
BR112022006644A2 (pt) 2019-10-30 2022-07-12 Astellas Inst For Regenerative Medicine Métodos para a produção de células epiteliais de pigmento da retina
WO2021102271A1 (en) * 2019-11-22 2021-05-27 Sigilon Therapeutics, Inc. Monoclonal cell lines expressing an exogenous substance and uses thereof
US12433289B2 (en) 2020-01-21 2025-10-07 Takeda Pharmaceutical Company Limited Compositions and methods of cryopreserving cells
WO2021159069A2 (en) * 2020-02-07 2021-08-12 The Trustees Of Columbia University In The City Of New York Reprogramming the metabolome to delay onset or treat neurodegeneration
WO2022009969A1 (ja) * 2020-07-10 2022-01-13 国立研究開発法人理化学研究所 網膜色素上皮細胞の移植用生着促進剤
CN112544612A (zh) * 2020-12-18 2021-03-26 江苏艾尔康生物医药科技有限公司 冻存液及其在rpe细胞冻存中的应用
CN112834411B (zh) * 2021-01-07 2022-05-27 上海交通大学 应用于质谱流式技术的金属纳米探针及制备方法和应用
WO2022164933A2 (en) * 2021-01-26 2022-08-04 Sigilon Therapeutics, Inc. Biocompatible devices for cell-based therapies and related methods
CN112926116B (zh) * 2021-03-01 2023-02-17 哈尔滨工业大学 一种基于虚拟现实的体育馆火灾疏散行为数据收集系统及其收集方法
CN114246938A (zh) * 2022-01-25 2022-03-29 中山大学中山眼科中心 Il-4在制备用于治疗视网膜变性疾病药物中的应用
WO2023149420A1 (ja) * 2022-02-01 2023-08-10 株式会社坪田ラボ 近視を予防または治療するための方法および組成物
CN114561356B (zh) * 2022-03-09 2022-09-13 北京呈诺医学科技有限公司 影响细胞因子分泌的方法及应用
WO2023176906A1 (ja) * 2022-03-16 2023-09-21 住友ファーマ株式会社 移植用媒体
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
WO2024218311A1 (fr) * 2023-04-21 2024-10-24 Pulsesight Therapeutics Compositions à base de décorine pour la réparation et la régéneration de l'épithélium pigmentaire de la rétine
EP4704870A1 (en) * 2023-05-05 2026-03-11 The Regents of University of California Retinal pigment epithelium cell therapy
CN117625536B (zh) * 2024-01-26 2024-04-30 中国人民解放军总医院第三医学中心 一种人视网膜色素上皮细胞的纯化、培养方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138205A (en) 1975-12-15 1979-02-06 Hydro Pulse Corporation Movable stator walls permitting access to tubing in peristaltic pump
US5610753A (en) 1991-12-12 1997-03-11 Eastman Kodak Company Optical design of laser scanner to reduce thermal sensitivity
GB9608145D0 (en) * 1996-04-19 1996-06-26 British Tech Group Wound healing
US20040086494A1 (en) * 1996-10-07 2004-05-06 John Constance Mary Immune privileged cells for delivery of proteins and peptides
US5998423A (en) 1996-10-08 1999-12-07 Therasys, Inc. Methods for modulating melanin production
AU9040098A (en) 1997-09-10 1999-03-29 University Of Florida Compounds and method for the prevention and treatment of diabetic retinopathy
NZ505459A (en) * 1998-01-02 2003-07-25 Titan Pharmaceuticals Inc Use of pigmented retinal epithelial cells for creation of an immune privilege site
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6943153B1 (en) 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US6576422B1 (en) * 2000-10-17 2003-06-10 Rohm And Haas Company Method for identifying products employing gene expression
AU2002236495B2 (en) 2000-11-29 2006-05-11 Allergan, Inc. Intraocular implants for preventing transplant rejection in the eye
EP1381349A4 (en) * 2001-04-27 2004-09-29 Gen Hospital Corp TYROSINASEBESTIMMUNG
US7319002B2 (en) * 2001-08-08 2008-01-15 The Trustees Of The University Of Pennsylvania Method for purification of viral vectors having proteins which bind sialic acid
MXPA04005010A (es) 2001-11-26 2005-04-08 Advanced Cell Tech Inc METODO PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS METODOS PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS HUMANOS REPROGRAMADOS Y CELULAS DEL TALLO HUMANAS AUTOLOGAS E ISOGENICAS.
WO2003060083A2 (en) 2002-01-15 2003-07-24 Advanced Cell Technology, Inc. Cloning b and t lymphocytes
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
US7803750B2 (en) 2002-07-29 2010-09-28 Duke University Method of modulating melanin production
AU2005207042B2 (en) * 2004-01-23 2010-09-09 President And Fellows Of Harvard College Improved modalities for the treatment of degenerative diseases of the retina
US7794704B2 (en) * 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
US7309487B2 (en) * 2004-02-09 2007-12-18 George Inana Methods and compositions for detecting and treating retinal diseases
EP2960328A1 (en) 2004-11-04 2015-12-30 Ocata Therapeutics, Inc. Derivation of embryonic stem cells
US7893315B2 (en) 2004-11-04 2011-02-22 Advanced Cell Technology, Inc. Derivation of embryonic stem cells and embryo-derived cells
CN101563449A (zh) * 2006-09-22 2009-10-21 理化学研究所 干细胞培养基及干细胞培养方法
CN104946591A (zh) * 2007-10-12 2015-09-30 奥卡塔治疗公司 制备rpe 细胞和rpe 细胞的组合物的改良方法
GB0806746D0 (en) 2008-04-14 2008-05-14 Ucl Business Plc Membrane
EP2273988B1 (en) * 2008-04-18 2015-09-09 Arizona Board Of Regents, A Body Corp. Of The State Of Arizona, Acting For And On Behalf Of The University Of Arizona L-dopa for treating age-related macular degeneration
EP2501802A4 (en) * 2009-11-17 2013-08-21 Advanced Cell Tech Inc METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS
AU2011280878B2 (en) * 2010-07-23 2016-06-16 Astellas Institute For Regenerative Medicine Methods for detection of rare subpopulations of cells and highly purified compositions of cells
US20110052678A1 (en) * 2010-11-05 2011-03-03 Shantha Totada R Method for treating age related macular degeneration
WO2012135621A2 (en) 2011-03-30 2012-10-04 Cellular Dynamics International. Inc Priming of pluripotent stem cells for neural differentiation
WO2012149484A2 (en) * 2011-04-29 2012-11-01 University Of Southern California Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate
IL287381B2 (en) * 2011-11-14 2024-04-01 Astellas Inst For Regenerative Medicine Pharmaceutical preparations of human rpe cells and uses thereof
JP6778181B2 (ja) * 2014-09-05 2020-10-28 アステラス インスティテュート フォー リジェネレイティブ メディシン 網膜神経節細胞およびその前駆体

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