JP2014532710A - 健康を促進するための胃腸細菌を調節する方法及び組成物 - Google Patents
健康を促進するための胃腸細菌を調節する方法及び組成物 Download PDFInfo
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- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
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- A61P37/04—Immunostimulants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
- A23L7/117—Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
- A23L7/126—Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/32—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
- A23V2200/3202—Prebiotics, ingredients fermented in the gastrointestinal tract by beneficial microflora
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| US201161555800P | 2011-11-04 | 2011-11-04 | |
| US61/555,800 | 2011-11-04 | ||
| PCT/US2012/063008 WO2013067146A1 (en) | 2011-11-04 | 2012-11-01 | Methods and compositions for modulating gastrointestinal bacteria to promote health |
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| JP2014532710A true JP2014532710A (ja) | 2014-12-08 |
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| EP (1) | EP2773357A4 (enExample) |
| JP (1) | JP2014532710A (enExample) |
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| CN (1) | CN104159588A (enExample) |
| AU (1) | AU2012332491A1 (enExample) |
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| CA (1) | CA2854398A1 (enExample) |
| IN (1) | IN2014CN04055A (enExample) |
| MX (1) | MX2014005433A (enExample) |
| WO (1) | WO2013067146A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017132763A (ja) * | 2016-01-26 | 2017-08-03 | 富士フイルム株式会社 | 腸内細菌数抑制剤、食品、及び医薬品 |
| JP2018532779A (ja) * | 2015-10-28 | 2018-11-08 | メタボゲン アーベー | 糖尿病及び腸疾患の治療又は予防における使用のためのフィーカリバクテリウムプラウスニッツィ及びデスルホビブリオピゲル |
| JP2021168651A (ja) * | 2020-04-16 | 2021-10-28 | サンスター株式会社 | フィーカリバクテリウム属細菌増殖用組成物、酪酸産生増加用組成物、及び腸内環境改善用組成物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201312713D0 (en) * | 2013-03-22 | 2013-08-28 | Weaver Connie M | Uses of soluble corn fibre for increasing colonic bacteria populations and increasing mineral absorption |
| EP4529950A3 (en) | 2014-10-31 | 2025-08-20 | Pendulum Therapeutics, Inc. | Methods and compositions relating to microbial treatment |
| CN107708714B (zh) * | 2015-04-14 | 2022-07-22 | 普梭梅根公司 | 用于内分泌系统状况的微生物组来源的诊断和治疗的方法及系统 |
| WO2016183535A1 (en) | 2015-05-14 | 2016-11-17 | University Of Puerto Rico | Methods for restoring microbiota of newborns |
| WO2017117142A1 (en) | 2015-12-28 | 2017-07-06 | New York University | Device and method of restoring microbiota of newborns |
| EP3431090A4 (en) * | 2016-03-14 | 2020-04-15 | B Food Science Co., Ltd. | PROLIFERATIVE AGENT FOR FAECALIBACTERIUM BACTERIA |
| US10799540B2 (en) * | 2016-09-06 | 2020-10-13 | Bgi Shenzhen | Faecalibacterium longum and application thereof |
| US12514897B2 (en) | 2017-06-02 | 2026-01-06 | Goodgut S.L. | Grape skin for use in the treatment of dysbiosis |
| WO2019046646A1 (en) | 2017-08-30 | 2019-03-07 | Whole Biome Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS |
| EP3466417A1 (en) * | 2017-10-04 | 2019-04-10 | Sorbonne Université | Compounds for the prevention and treatment of glucose intolerance related conditions and obesity |
| EP3723775A4 (en) | 2017-12-15 | 2022-04-13 | Solarea Bio, Inc. | MICROBIAL COMPOSITIONS AND METHODS OF TREATING TYPE 2 DIABETES, OBESITY AND METABOLIC SYNDROME |
| CN109998112B (zh) * | 2017-12-22 | 2024-05-14 | 奥地利商艾尔柏有限公司 | 红蝽杆菌纲促进肠道健康的用途 |
| WO2019158546A1 (en) * | 2018-02-14 | 2019-08-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Polydextrose for the treatment of inflammatory diseases |
| WO2019216815A1 (en) * | 2018-05-09 | 2019-11-14 | Carbiotix Ab | Method for measuring and improving gut health |
| WO2019227418A1 (zh) * | 2018-05-31 | 2019-12-05 | 深圳华大生命科学研究院 | 一种组合物及其应用 |
| CN113164526A (zh) | 2018-07-19 | 2021-07-23 | 潘德勒姆治疗公司 | 用于微生物植入的方法和组合物 |
| WO2020051379A1 (en) | 2018-09-05 | 2020-03-12 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases |
| US11980647B2 (en) | 2018-09-05 | 2024-05-14 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause |
| ES2763874B2 (es) * | 2018-11-30 | 2020-10-13 | Consejo Superior Investigacion | Phascolarctobacterium faecium para su uso en la prevencion y tratamiento de la obesidad y sus comorbilidades |
| JP7624449B2 (ja) * | 2019-10-07 | 2025-01-30 | シオルタ・セラピューティクス，インコーポレイテッド | 治療用医薬組成物 |
| KR102174095B1 (ko) * | 2019-12-11 | 2020-11-05 | 주식회사 에이치이엠 | 신규한 엔테로코커스 패시움 hem 200 균주, 및 상기 균주 또는 이의 배양물을 포함하는 장내 환경 개선용 조성물 |
| CA3175308A1 (en) * | 2020-03-13 | 2021-09-16 | Fitbiomics Inc. | Probiotic compositions for improving human health and athletic performance |
| EP4333644A1 (en) * | 2021-05-06 | 2024-03-13 | Société des Produits Nestlé S.A. | Compositions and methods using at least one of inositol, erythritol or sorbitol to enhance growth of faecalibacterium prausnitzii |
| EP4436407A1 (en) | 2021-11-22 | 2024-10-02 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause |
| US20230190834A1 (en) | 2021-12-21 | 2023-06-22 | Solarea Bio, Inc. | Immunomodulatory compositions comprising microbial entities |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002306130A (ja) * | 2001-04-09 | 2002-10-22 | Snow Brand Milk Prod Co Ltd | 肥満予防改善飲食品 |
| JP2003334025A (ja) * | 2002-05-15 | 2003-11-25 | Toyo Shinyaku:Kk | 健康食品 |
| WO2010129839A1 (en) * | 2009-05-07 | 2010-11-11 | Tate & Lyle Ingredients France SAS | Compositions and methods for making alpha-(1,2)-branched alpha-(1,6) oligodextrans |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0394655A (ja) * | 1989-09-06 | 1991-04-19 | Otsuka Pharmaceut Co Ltd | 栄養補給用組成物 |
| FI20020078A7 (fi) * | 2002-01-15 | 2003-07-16 | Danisco | Immuunijärjestelmän stimulointi polydextroosilla |
| DK1530642T3 (da) * | 2002-08-06 | 2010-03-08 | Danisco | Brug af lactobacillus til fremstilling af exopolysaccharider i fødevarer og farmaceutiske sammensætninger |
| GB0302872D0 (en) * | 2003-02-10 | 2003-03-12 | Univ Liverpool | Treatment of inflammatory bowel disease |
| WO2008147798A2 (en) * | 2007-05-23 | 2008-12-04 | Tate & Lyle Ingredients Americas, Inc. | Edible composition comprising a slowly digestible or digestion resistant oligosaccharide composition |
| GB0903016D0 (en) * | 2009-02-23 | 2009-04-08 | Univ Gent | Method for alleviating intestinal problems and novel bacterial strains therefor |
-
2012
- 2012-11-01 BR BR112014010660A patent/BR112014010660A2/pt not_active IP Right Cessation
- 2012-11-01 IN IN4055CHN2014 patent/IN2014CN04055A/en unknown
- 2012-11-01 US US14/355,963 patent/US20150209383A1/en not_active Abandoned
- 2012-11-01 AU AU2012332491A patent/AU2012332491A1/en not_active Abandoned
- 2012-11-01 KR KR1020147014663A patent/KR20140093252A/ko not_active Withdrawn
- 2012-11-01 JP JP2014540070A patent/JP2014532710A/ja active Pending
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- 2012-11-01 CA CA2854398A patent/CA2854398A1/en not_active Abandoned
- 2012-11-01 CN CN201280064861.5A patent/CN104159588A/zh active Pending
- 2012-11-01 MX MX2014005433A patent/MX2014005433A/es not_active Application Discontinuation
- 2012-11-01 WO PCT/US2012/063008 patent/WO2013067146A1/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002306130A (ja) * | 2001-04-09 | 2002-10-22 | Snow Brand Milk Prod Co Ltd | 肥満予防改善飲食品 |
| JP2003334025A (ja) * | 2002-05-15 | 2003-11-25 | Toyo Shinyaku:Kk | 健康食品 |
| WO2010129839A1 (en) * | 2009-05-07 | 2010-11-11 | Tate & Lyle Ingredients France SAS | Compositions and methods for making alpha-(1,2)-branched alpha-(1,6) oligodextrans |
Non-Patent Citations (4)
| Title |
|---|
| JPN6016028458; Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｎｕｔｒｉｔｉｏｎ， ２０１１， ｖｏｌ．１４１， ｐ．１３１８-１３２５ * |
| JPN6016028459; Ｐａｋ． Ｊ． Ｍｅｄ． Ｓｃｉ．， ２００９， ｖｏｌ．２５， Ｎｏ．４， ｐ．５７３-５７８ * |
| JPN6016028460; Ｔｈｅ ＦＡＳＥＢ Ｊｏｕｒｎａｌ， ２０１１．４， ｖｏｌ．２５， Ｎｏ．１， Ｓｕｐｐｌｅｍｅｎｔ９３．５ * |
| JPN6016028461; Ｔｈｅ ＦＡＳＥＢ Ｊｏｕｒｎａｌ， ２０１１．４， ｖｏｌ．２５， Ｎｏ．１， Ｓｕｐｐｌｅｍｅｎｔ５８７．３ * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018532779A (ja) * | 2015-10-28 | 2018-11-08 | メタボゲン アーベー | 糖尿病及び腸疾患の治療又は予防における使用のためのフィーカリバクテリウムプラウスニッツィ及びデスルホビブリオピゲル |
| JP7018396B2 (ja) | 2015-10-28 | 2022-02-10 | メタボゲン アーベー | 糖尿病及び腸疾患の治療又は予防における使用のためのフィーカリバクテリウムプラウスニッツィ及びデスルホビブリオピゲル |
| JP2017132763A (ja) * | 2016-01-26 | 2017-08-03 | 富士フイルム株式会社 | 腸内細菌数抑制剤、食品、及び医薬品 |
| US10398745B2 (en) | 2016-01-26 | 2019-09-03 | Fujifilm Corporation | Agent for reducing the number of intestinal bacteria, food, and pharmaceutical product |
| JP2021168651A (ja) * | 2020-04-16 | 2021-10-28 | サンスター株式会社 | フィーカリバクテリウム属細菌増殖用組成物、酪酸産生増加用組成物、及び腸内環境改善用組成物 |
| JP7824034B2 (ja) | 2020-04-16 | 2026-03-04 | サンスター株式会社 | フィーカリバクテリウム属細菌増殖用組成物、酪酸産生増加用組成物、及び腸内環境改善用組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20150209383A1 (en) | 2015-07-30 |
| KR20140093252A (ko) | 2014-07-25 |
| CA2854398A1 (en) | 2013-05-10 |
| EP2773357A4 (en) | 2015-08-26 |
| AU2012332491A1 (en) | 2014-05-29 |
| WO2013067146A1 (en) | 2013-05-10 |
| IN2014CN04055A (enExample) | 2015-10-23 |
| MX2014005433A (es) | 2014-08-22 |
| CN104159588A (zh) | 2014-11-19 |
| EP2773357A1 (en) | 2014-09-10 |
| BR112014010660A2 (pt) | 2017-05-09 |
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