JP2014530803A5 - - Google Patents

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JP2014530803A5
JP2014530803A5 JP2014523434A JP2014523434A JP2014530803A5 JP 2014530803 A5 JP2014530803 A5 JP 2014530803A5 JP 2014523434 A JP2014523434 A JP 2014523434A JP 2014523434 A JP2014523434 A JP 2014523434A JP 2014530803 A5 JP2014530803 A5 JP 2014530803A5
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mir
nucleic acid
precursor
modified
polynucleotide
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JP2014523434A
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JP6309450B2 (ja
JP2014530803A (ja
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Priority claimed from PCT/IB2012/053971 external-priority patent/WO2013018060A2/en
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JP2014523434A 2011-08-04 2012-08-02 セロトニン関連の医学的状態、アドレナリン関連の医学的状態、ノルアドレナリン関連の医学的状態、グルタミン酸関連の医学的状態および副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのミクロｒｎａおよび該ミクロｒｎａを含む組成物 Active JP6309450B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161514954P 2011-08-04 2011-08-04
US61/514,954 2011-08-04
PCT/IB2012/053971 WO2013018060A2 (en) 2011-08-04 2012-08-02 Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions

Related Child Applications (1)

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JP2016254743A Division JP2017095482A (ja) 2011-08-04 2016-12-28 セロトニン関連の医学的状態、アドレナリン関連の医学的状態、ノルアドレナリン関連の医学的状態、グルタミン酸関連の医学的状態および副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのミクロｒｎａおよび該ミクロｒｎａを含む組成物

Publications (3)

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JP2014530803A JP2014530803A (ja) 2014-11-20
JP2014530803A5 true JP2014530803A5 (enExample) 2015-07-09
JP6309450B2 JP6309450B2 (ja) 2018-04-11

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JP2014523434A Active JP6309450B2 (ja) 2011-08-04 2012-08-02 セロトニン関連の医学的状態、アドレナリン関連の医学的状態、ノルアドレナリン関連の医学的状態、グルタミン酸関連の医学的状態および副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのミクロｒｎａおよび該ミクロｒｎａを含む組成物
JP2016254743A Pending JP2017095482A (ja) 2011-08-04 2016-12-28 セロトニン関連の医学的状態、アドレナリン関連の医学的状態、ノルアドレナリン関連の医学的状態、グルタミン酸関連の医学的状態および副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのミクロｒｎａおよび該ミクロｒｎａを含む組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016254743A Pending JP2017095482A (ja) 2011-08-04 2016-12-28 セロトニン関連の医学的状態、アドレナリン関連の医学的状態、ノルアドレナリン関連の医学的状態、グルタミン酸関連の医学的状態および副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのミクロｒｎａおよび該ミクロｒｎａを含む組成物

Country Status (10)

Country Link
US (5) US9150858B2 (enExample)
EP (3) EP3524679B1 (enExample)
JP (2) JP6309450B2 (enExample)
CN (3) CN104039960B (enExample)
BR (1) BR112014002737B1 (enExample)
CA (2) CA2844012C (enExample)
ES (2) ES2632212T3 (enExample)
HU (2) HUE044154T2 (enExample)
IL (1) IL230814A (enExample)
WO (1) WO2013018060A2 (enExample)

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US9150858B2 (en) 2011-08-04 2015-10-06 Yeda Research And Development Co. Ltd. Micro-RNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
CN110511924B (zh) * 2013-11-27 2023-11-03 西格马-奥尔德里奇有限责任公司 从生物流体中分离微小rna
CN106715695B (zh) * 2014-02-05 2020-07-31 耶达研究及发展有限公司 用于治疗和诊断的微rna和包含所述微rna的组合物
US10370717B2 (en) 2014-04-22 2019-08-06 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Methods for the measurement of post-traumatic stress disorder microRNA markers
EP3204967B1 (en) * 2014-10-09 2018-07-25 Consorzio Delta Ti Research 3d integrated thermoelectric generator operating in an out-of-plane heat flux configuration with internal voids and heat conduction paths conditioning vias
CN104826131B (zh) * 2015-04-15 2018-12-18 涛康生物科技（上海）有限公司 miR-17-92基因簇在制备治疗精神类疾病药物中的用途
CN105349643B (zh) * 2015-11-05 2018-09-07 中国航天员科研训练中心 预测睡眠剥夺后5-羟色胺变化的方法与microRNAs标志物
CA3042630A1 (en) * 2015-11-18 2017-05-26 Dignity Health Methods of diagnosing epilepsy
CN105709240B (zh) * 2016-03-23 2020-07-07 中国人民解放军第四军医大学 一种miR-26a抑制剂及其应用
CN105748501B (zh) * 2016-03-31 2017-07-28 成都仕康美生物科技有限公司 一种miRNA‑182抑制剂及其在制备防治心脏移植免疫排斥反应药物中的应用
WO2019086603A1 (en) * 2017-11-03 2019-05-09 Interna Technologies B.V. Mirna molecule, equivalent, antagomir, or source thereof for treating and/or diagnosing a condition and/or a disease associated with neuronal deficiency or for neuronal (re)generation
CN112368051A (zh) 2018-03-23 2021-02-12 马萨诸塞大学 用于治疗骨病的基因治疗剂
CA3019970A1 (en) * 2018-10-05 2020-04-05 Fang Liu Methods for diagnosing or treating post-traumatic stress disorder, and compositions therefor
CN112852961B (zh) * 2021-01-08 2022-09-13 上海市胸科医院 肺腺癌铁死亡敏感性标志物adcy10及其应用
CN113897435B (zh) * 2021-11-22 2024-08-06 山西农业大学 一种用于评估黑色素瘤转移风险的miRNA及其应用
WO2023182507A1 (ja) * 2022-03-24 2023-09-28 北海道公立大学法人 札幌医科大学 薬学的組成物、間葉系幹細胞の三次元培養物の製造方法、エクソソームの製造方法、および薬学的組成物の製造方法
WO2024020376A1 (en) * 2022-07-22 2024-01-25 University Of Massachusetts Aav-mediated delivery of osteoblast/osteoclast-regulating mirnas for osteoporosis therapy

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JP2024503711A (ja) 2021-01-18 2024-01-26 イェダ リサーチ アンド デベロップメント カンパニー リミテッド 修飾ｍｉＲ－１３５、そのコンジュゲートおよびその使用

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