JP2014530219A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014530219A5 JP2014530219A5 JP2014534512A JP2014534512A JP2014530219A5 JP 2014530219 A5 JP2014530219 A5 JP 2014530219A5 JP 2014534512 A JP2014534512 A JP 2014534512A JP 2014534512 A JP2014534512 A JP 2014534512A JP 2014530219 A5 JP2014530219 A5 JP 2014530219A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoparticles
- nanoparticle
- pharmaceutical composition
- sterol
- quillaja
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161542425P | 2011-10-03 | 2011-10-03 | |
| US61/542,425 | 2011-10-03 | ||
| PCT/SE2012/051048 WO2013051994A1 (en) | 2011-10-03 | 2012-10-01 | Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrophobic molecules in fields of medicine including cancer treatment and food related compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014530219A JP2014530219A (ja) | 2014-11-17 |
| JP2014530219A5 true JP2014530219A5 (enExample) | 2015-11-19 |
| JP6050822B2 JP6050822B2 (ja) | 2016-12-21 |
Family
ID=47143250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014534512A Active JP6050822B2 (ja) | 2011-10-03 | 2012-10-01 | ナノ粒子、ナノ粒子の調製のための処理、および癌治療および食品関連化合物を含む医療分野における両親媒性分子または疎水性分子ための担体としてのナノ粒子の使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10047116B2 (enExample) |
| EP (3) | EP4176871A1 (enExample) |
| JP (1) | JP6050822B2 (enExample) |
| KR (1) | KR102090740B1 (enExample) |
| CN (1) | CN103857403B (enExample) |
| AU (1) | AU2012319239B2 (enExample) |
| CA (1) | CA2850296C (enExample) |
| DK (2) | DK2750683T4 (enExample) |
| ES (1) | ES2673957T5 (enExample) |
| HR (1) | HRP20180956T1 (enExample) |
| IN (1) | IN2014DN03485A (enExample) |
| PL (1) | PL2750683T3 (enExample) |
| PT (1) | PT2750683T (enExample) |
| RS (1) | RS57350B1 (enExample) |
| TR (1) | TR201808733T4 (enExample) |
| WO (1) | WO2013051994A1 (enExample) |
| ZA (1) | ZA201402040B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2750683T4 (da) * | 2011-10-03 | 2021-04-12 | Croda Int Plc | Nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf som bærer for amfipatiske eller hydrofobe molekyler inden for medicin, herunder cancerbehandling, og i fødevarerelaterede forbindelser |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| EP2777402A1 (en) | 2013-03-15 | 2014-09-17 | DSM IP Assets B.V. | Solid lipid nanoparticles (I) |
| WO2014163558A1 (en) | 2013-04-01 | 2014-10-09 | Moreinx Ab | Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds |
| CN105939767B (zh) | 2014-01-08 | 2018-04-06 | 弗洛设计声能学公司 | 具有双声电泳腔的声电泳装置 |
| CN104382856B (zh) * | 2014-12-04 | 2017-11-14 | 中国药科大学 | 一种去氧鬼臼毒素长循环脂质体冻干制剂 |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| EP3529347A1 (en) | 2016-10-19 | 2019-08-28 | Flodesign Sonics, Inc. | Affinity cell extraction by acoustics |
| US11478433B2 (en) | 2017-06-23 | 2022-10-25 | Yale University | Nanomaterials with enhanced drug delivery efficiency |
| CN114900773A (zh) | 2017-12-14 | 2022-08-12 | 弗洛设计声能学公司 | 声泳系统及其操作方法、控制声换能器及声学系统的方法 |
| EP3669890A1 (en) * | 2018-12-18 | 2020-06-24 | Croda International PLC | Filamentous nanoparticles having vaccine adjuvant effect |
| JP7597554B2 (ja) * | 2020-10-30 | 2024-12-10 | 株式会社ニップン | オキシトシン受容体作動性組成物 |
| CN116077639A (zh) * | 2023-01-05 | 2023-05-09 | 国药中生生物技术研究院有限公司 | 雷公藤红素或其可药用衍生物在制备疫苗佐剂中的用途 |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2802005A (en) | 1957-08-06 | S-eluorourace | ||
| US3046301A (en) | 1959-10-29 | 1962-07-24 | Burroughs Wellcome Co | Method of making chlorambucil |
| US3803124A (en) | 1968-04-12 | 1974-04-09 | Farmaceutici It Soc | Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives |
| GB1235022A (en) | 1969-06-04 | 1971-06-09 | Laeaeke Ag | A new method for the production of cyclophosphamide |
| DE2124023C3 (de) | 1970-05-27 | 1980-07-10 | Richter Gedeon Vegyeszeti Gyar R.T., Budapest | Verfahren zur selektiven Gewinnung von Vinblastin, Vinleurosin und Vincristin oder von deren Sulfaten |
| US4020270A (en) | 1974-05-02 | 1977-04-26 | Societa' Farmaceutici Italia S.P.A. | L-lyxohex-1-enopyranose derivative |
| GB1467383A (en) | 1974-06-12 | 1977-03-16 | Farmaceutici Italia | Daunomycin analogues |
| US4307100A (en) | 1978-08-24 | 1981-12-22 | Agence Nationale De Valorisation De La Recherche (Anvar) | Nor bis-indole compounds usable as medicaments |
| DE2845574A1 (de) | 1978-10-19 | 1980-04-24 | Deutsches Krebsforsch | Durch heterocyclische ringe oder alkylreste substituierte analoga von ccnu und verfahren zu deren herstellung |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| EP0111058B1 (en) | 1982-11-26 | 1987-11-04 | Nippon Kayaku Kabushiki Kaisha | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| US4526988A (en) | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
| JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| SE8405493D0 (sv) | 1984-11-01 | 1984-11-01 | Bror Morein | Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel |
| ES2039229T3 (es) * | 1986-01-14 | 1993-09-16 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Procedimiento para la preparacion de complejos inmunogenicos y composiciones farmaceuticas que contienen estos complejos. |
| FR2601675B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2601676B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
| US5004758A (en) | 1987-12-01 | 1991-04-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells |
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| JPH0679958B2 (ja) | 1988-10-07 | 1994-10-12 | 東レ株式会社 | 糸条の巻取装置 |
| GB8919819D0 (en) | 1989-09-01 | 1989-10-18 | Coopers Animal Health | Complexes having adjuvant activity |
| NL9002314A (nl) * | 1990-10-23 | 1992-05-18 | Nederlanden Staat | Immunogene complexen, in het bijzonder iscoms. |
| MX9102128A (es) | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
| SE502569C2 (sv) * | 1991-05-31 | 1995-11-13 | British Tech Group | Användning av en immunologiskt inert matris av en sterol och saponiner som kan bilda sfäriska nanopartiklar med snäv storleksfördelning som läkemedelsbärare, partiklar, komposition samt kit |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| EP0590058B1 (en) | 1991-06-14 | 2003-11-26 | Genentech, Inc. | HUMANIZED Heregulin ANTIBODy |
| IT1250692B (it) | 1991-07-23 | 1995-04-21 | Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi. | |
| US5650398A (en) * | 1992-07-02 | 1997-07-22 | Cambridge Biotech Corporation | Drug delivery enhancement via modified saponins |
| US5476932A (en) | 1994-08-26 | 1995-12-19 | Hoffmann-La Roche Inc. | Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives |
| AUPM873294A0 (en) * | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| US20010053365A1 (en) * | 1995-04-25 | 2001-12-20 | Smithkline Beecham Biologicals S.A. | Vaccines |
| SE9600647D0 (sv) | 1996-02-21 | 1996-02-21 | Bror Morein | Ny användning |
| GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| GB9719426D0 (en) | 1997-09-13 | 1997-11-12 | Johnson Matthey Plc | Novel process |
| GB9817052D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| DE59903869D1 (de) * | 1998-10-14 | 2003-01-30 | Cognis Deutschland Gmbh | Verwendung von nanoskaligen sterolen und sterolestern |
| SI1650221T1 (sl) * | 2000-02-23 | 2012-09-28 | Glaxosmithkline Biolog Sa | Nove spojine |
| US7713942B2 (en) * | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
| DE60229118D1 (de) | 2001-04-04 | 2008-11-13 | Nordic Vaccine Technology As | Polynukleotide-bindende komplexe die sterolen und saponine enthalten |
| WO2002102311A2 (en) * | 2001-06-15 | 2002-12-27 | Cornerstone Pharmaceuticals | Nanoparticles for treating targeted tissues and cells |
| GB0123580D0 (en) * | 2001-10-01 | 2001-11-21 | Glaxosmithkline Biolog Sa | Vaccine |
| US7482018B2 (en) * | 2001-12-21 | 2009-01-27 | Soane Family Trust | Use of oligomers and polymers for drug solubilization, stabilization, and delivery |
| US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
| SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
| JP2006503072A (ja) | 2002-10-02 | 2006-01-26 | ノルディック ワクチン テクノロジー アクティーゼルスカブ | ワクチン接種用組成物 |
| SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
| US20050175623A1 (en) * | 2004-02-10 | 2005-08-11 | Zheng-Pin Wang | Saponins as anticancer agent |
| US20080194494A1 (en) * | 2005-04-26 | 2008-08-14 | Microbia, Inc. | 4-Biarylyl-1-Phenylazetidin-2-One Glucuronide Derivatives for Hypercholesterolemia |
| KR100641060B1 (ko) * | 2005-07-22 | 2006-11-01 | 삼성전자주식회사 | 게이트 구조물의 제조 방법 및 이를 이용하는 반도체장치의 제조 방법 |
| DE102006007903A1 (de) | 2005-12-21 | 2007-07-05 | VD-Werkstätten GmbH & Co KG | Verfahren für die Herstellung von Möbel-Formteilen |
| CA2637194A1 (en) * | 2006-01-18 | 2007-07-26 | National University Corporation Tokyo Medical And Dental University | Biomaterial for osteogenesis containing osteogenesis promoter and nanogel |
| CN101563090B (zh) * | 2006-11-20 | 2013-01-02 | 杜科姆公司 | 包含南美皂皮树皂苷的含脂质颗粒用于治疗癌症的用途 |
| CN101848702B (zh) * | 2006-12-01 | 2013-07-17 | 安特里奥公司 | 两亲实体纳米粒子 |
| JP2010514431A (ja) * | 2006-12-29 | 2010-05-06 | エボニック デグサ ゲーエムベーハー | 生成物阻害が低減されたメチオニンシンターゼ |
| US20080311045A1 (en) * | 2007-06-06 | 2008-12-18 | Biovaluation & Analysis, Inc. | Polymersomes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo |
| MX2010003642A (es) * | 2007-10-12 | 2010-08-09 | Massachusetts Inst Technology | Nanotecnologia de vacuna. |
| SG185294A1 (en) * | 2007-10-12 | 2012-11-29 | Csl Ltd | Method of eliciting an immune response against pandemic influenza virus |
| ES2569907T3 (es) * | 2008-06-27 | 2016-05-13 | Zoetis Services Llc | Composiciones adyuvantes novedosas |
| WO2010023216A1 (en) * | 2008-08-28 | 2010-03-04 | Glaxosmithkline Biologicals S.A. | Vaccine |
| JP5344558B2 (ja) * | 2008-10-31 | 2013-11-20 | 国立大学法人 東京医科歯科大学 | カチオン性ナノゲルを用いる粘膜ワクチン |
| PL2445526T3 (pl) * | 2009-06-24 | 2017-08-31 | Glaxosmithkline Biologicals S.A. | Rekombinowane antygeny rsv |
| SG176807A1 (en) * | 2009-06-24 | 2012-01-30 | Id Biomedical Corp Quebec | Vaccine |
| CN102470168A (zh) | 2009-07-10 | 2012-05-23 | 伊斯克诺瓦公司 | 新组合物 |
| JP5833145B2 (ja) * | 2011-02-04 | 2015-12-16 | ゾエティス・エルエルシー | 免疫原性ｂｏｒｄｅｔｅｌｌａｂｒｏｎｃｈｉｓｅｐｔｉｃａ組成物 |
| JP2014519496A (ja) * | 2011-05-11 | 2014-08-14 | ナノヴァレント ファーマシューティカルズ，インコーポレイテッド | Ａｌｃａｍ細胞表面受容体を標的とする細胞毒性重合リポソームナノ粒子による増強された骨肉腫の増殖抑制 |
| DK2750683T4 (da) * | 2011-10-03 | 2021-04-12 | Croda Int Plc | Nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf som bærer for amfipatiske eller hydrofobe molekyler inden for medicin, herunder cancerbehandling, og i fødevarerelaterede forbindelser |
| GB201119999D0 (en) * | 2011-11-20 | 2012-01-04 | Glaxosmithkline Biolog Sa | Vaccine |
| WO2014163558A1 (en) | 2013-04-01 | 2014-10-09 | Moreinx Ab | Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds |
| CN110418593B (zh) | 2017-10-20 | 2022-04-19 | 科亚列士信荣株式会社 | 半成品卷制造装置 |
-
2012
- 2012-10-01 DK DK12781489.5T patent/DK2750683T4/da active
- 2012-10-01 WO PCT/SE2012/051048 patent/WO2013051994A1/en not_active Ceased
- 2012-10-01 EP EP22214948.6A patent/EP4176871A1/en not_active Withdrawn
- 2012-10-01 CA CA2850296A patent/CA2850296C/en active Active
- 2012-10-01 US US14/349,142 patent/US10047116B2/en active Active
- 2012-10-01 EP EP17207322.3A patent/EP3311827B1/en active Active
- 2012-10-01 PT PT127814895T patent/PT2750683T/pt unknown
- 2012-10-01 KR KR1020147011942A patent/KR102090740B1/ko active Active
- 2012-10-01 ES ES12781489T patent/ES2673957T5/es active Active
- 2012-10-01 IN IN3485DEN2014 patent/IN2014DN03485A/en unknown
- 2012-10-01 AU AU2012319239A patent/AU2012319239B2/en active Active
- 2012-10-01 RS RS20180720A patent/RS57350B1/sr unknown
- 2012-10-01 HR HRP20180956TT patent/HRP20180956T1/hr unknown
- 2012-10-01 CN CN201280048961.9A patent/CN103857403B/zh active Active
- 2012-10-01 TR TR2018/08733T patent/TR201808733T4/tr unknown
- 2012-10-01 JP JP2014534512A patent/JP6050822B2/ja active Active
- 2012-10-01 PL PL12781489T patent/PL2750683T3/pl unknown
- 2012-10-01 EP EP12781489.5A patent/EP2750683B2/en active Active
- 2012-10-01 DK DK17207322.3T patent/DK3311827T3/da active
-
2014
- 2014-03-24 ZA ZA2014/02040A patent/ZA201402040B/en unknown
-
2017
- 2017-05-25 US US15/605,595 patent/US10100078B2/en active Active
- 2017-11-16 US US15/815,488 patent/US10487107B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Bezbaruah et al. | Nanoparticle-based delivery systems for vaccines | |
| Witika et al. | Current advances in specialised niosomal drug delivery: manufacture, characterization and drug delivery applications | |
| Chountoulesi et al. | Lyotropic liquid crystalline nanostructures as drug delivery systems and vaccine platforms | |
| Duong et al. | Recent advances in intranasal liposomes for drug, gene, and vaccine delivery | |
| Zhang et al. | pH-responsive nanoparticles targeted to lungs for improved therapy of acute lung inflammation/injury | |
| Kumar et al. | Nanocarriers in tuberculosis treatment: challenges and delivery strategies | |
| HRP20180956T1 (hr) | Nanočestice, postupak dobivanja i njihova primjena kao nosača amfipatičnih ili hidrofobnih molekula u medicini, uključujući i terapiju karcinoma, kao i prehrambenih spojeva | |
| Juere et al. | In vitro dissolution, cellular membrane permeability, and anti-inflammatory response of resveratrol-encapsulated mesoporous silica nanoparticles | |
| Binaymotlagh et al. | Liposome–hydrogel composites for controlled drug delivery applications | |
| Colley et al. | Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluation | |
| Elsayed et al. | Design and characterisation of novel Sorafenib-loaded carbon nanotubes with distinct tumour-suppressive activity in hepatocellular carcinoma | |
| JP2022003102A (ja) | 異なる医薬品の制御送達のためのビヒクル | |
| Zhao et al. | Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review | |
| Praphakar et al. | Targeted delivery of rifampicin to tuberculosis-infected macrophages: design, in-vitro, and in-vivo performance of rifampicin-loaded poly (ester amide) s nanocarriers | |
| Yan et al. | A novel type of aqueous dispersible ultrathin-layered double hydroxide nanosheets for in vivo bioimaging and drug delivery | |
| Kumar et al. | Nanomedicine in drug delivery | |
| Ali et al. | Enhancing the solubility and oral bioavailability of poorly water-soluble drugs using monoolein cubosomes | |
| JP2012517987A5 (ja) | 吸入用の医薬組成物のｆｐｄ特性を設定する方法 | |
| CN112074298B (zh) | Langerin+细胞靶向 | |
| Shi et al. | Optimization of process variables of zanamivir-loaded solid lipid nanoparticles and the prediction of their cellular transport in Caco-2 cell model | |
| JP2015515992A5 (enExample) | ||
| HN2011000864A (es) | Particulas inhalables que comprenden tiotropio | |
| Lin et al. | Co-delivery of imiquimod and plasmid DNA via an amphiphilic pH-responsive star polymer that forms unimolecular micelles in water | |
| WO2015079952A1 (ja) | アジュバント組成物およびこれを含むワクチン組成物、並びにこれらの製造方法 | |
| CN105188710A (zh) | 包含缓冲的氨基烷基氨基葡糖苷磷酸酯衍生物的组合物及其用于增强免疫应答的用途 |