JP2014530219A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014530219A5 JP2014530219A5 JP2014534512A JP2014534512A JP2014530219A5 JP 2014530219 A5 JP2014530219 A5 JP 2014530219A5 JP 2014534512 A JP2014534512 A JP 2014534512A JP 2014534512 A JP2014534512 A JP 2014534512A JP 2014530219 A5 JP2014530219 A5 JP 2014530219A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoparticles
- nanoparticle
- pharmaceutical composition
- sterol
- quillaja
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161542425P | 2011-10-03 | 2011-10-03 | |
| US61/542,425 | 2011-10-03 | ||
| PCT/SE2012/051048 WO2013051994A1 (en) | 2011-10-03 | 2012-10-01 | Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrophobic molecules in fields of medicine including cancer treatment and food related compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014530219A JP2014530219A (ja) | 2014-11-17 |
| JP2014530219A5 true JP2014530219A5 (enExample) | 2015-11-19 |
| JP6050822B2 JP6050822B2 (ja) | 2016-12-21 |
Family
ID=47143250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014534512A Active JP6050822B2 (ja) | 2011-10-03 | 2012-10-01 | ナノ粒子、ナノ粒子の調製のための処理、および癌治療および食品関連化合物を含む医療分野における両親媒性分子または疎水性分子ための担体としてのナノ粒子の使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10047116B2 (enExample) |
| EP (3) | EP4176871A1 (enExample) |
| JP (1) | JP6050822B2 (enExample) |
| KR (1) | KR102090740B1 (enExample) |
| CN (1) | CN103857403B (enExample) |
| AU (1) | AU2012319239B2 (enExample) |
| CA (1) | CA2850296C (enExample) |
| DK (2) | DK3311827T3 (enExample) |
| ES (1) | ES2673957T5 (enExample) |
| HR (1) | HRP20180956T1 (enExample) |
| IN (1) | IN2014DN03485A (enExample) |
| PL (1) | PL2750683T3 (enExample) |
| PT (1) | PT2750683T (enExample) |
| RS (1) | RS57350B1 (enExample) |
| TR (1) | TR201808733T4 (enExample) |
| WO (1) | WO2013051994A1 (enExample) |
| ZA (1) | ZA201402040B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6050822B2 (ja) | 2011-10-03 | 2016-12-21 | モレインクス,エービー | ナノ粒子、ナノ粒子の調製のための処理、および癌治療および食品関連化合物を含む医療分野における両親媒性分子または疎水性分子ための担体としてのナノ粒子の使用 |
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| EP2777402A1 (en) * | 2013-03-15 | 2014-09-17 | DSM IP Assets B.V. | Solid lipid nanoparticles (I) |
| US9907846B2 (en) | 2013-04-01 | 2018-03-06 | Mx Adjuvac Ab | Nanoparticles, composed of sterol and saponin from Quillaja saponaria Molina for use in pharmaceutical compositions |
| CA2935960C (en) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Acoustophoresis device with dual acoustophoretic chamber |
| CN104382856B (zh) * | 2014-12-04 | 2017-11-14 | 中国药科大学 | 一种去氧鬼臼毒素长循环脂质体冻干制剂 |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| CN110494543A (zh) | 2016-10-19 | 2019-11-22 | 弗洛设计声能学公司 | 通过声学的亲和细胞提取 |
| US11478433B2 (en) | 2017-06-23 | 2022-10-25 | Yale University | Nanomaterials with enhanced drug delivery efficiency |
| SG11202003907WA (en) | 2017-12-14 | 2020-05-28 | Flodesign Sonics Inc | Acoustic transducer drive and controller |
| EP3669890A1 (en) * | 2018-12-18 | 2020-06-24 | Croda International PLC | Filamentous nanoparticles having vaccine adjuvant effect |
| JP7597554B2 (ja) * | 2020-10-30 | 2024-12-10 | 株式会社ニップン | オキシトシン受容体作動性組成物 |
| CN116077639A (zh) * | 2023-01-05 | 2023-05-09 | 国药中生生物技术研究院有限公司 | 雷公藤红素或其可药用衍生物在制备疫苗佐剂中的用途 |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2802005A (en) | 1957-08-06 | S-eluorourace | ||
| US3046301A (en) | 1959-10-29 | 1962-07-24 | Burroughs Wellcome Co | Method of making chlorambucil |
| US3803124A (en) | 1968-04-12 | 1974-04-09 | Farmaceutici It Soc | Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives |
| GB1235022A (en) | 1969-06-04 | 1971-06-09 | Laeaeke Ag | A new method for the production of cyclophosphamide |
| DE2124023C3 (de) | 1970-05-27 | 1980-07-10 | Richter Gedeon Vegyeszeti Gyar R.T., Budapest | Verfahren zur selektiven Gewinnung von Vinblastin, Vinleurosin und Vincristin oder von deren Sulfaten |
| US4020270A (en) | 1974-05-02 | 1977-04-26 | Societa' Farmaceutici Italia S.P.A. | L-lyxohex-1-enopyranose derivative |
| GB1467383A (en) | 1974-06-12 | 1977-03-16 | Farmaceutici Italia | Daunomycin analogues |
| US4307100A (en) | 1978-08-24 | 1981-12-22 | Agence Nationale De Valorisation De La Recherche (Anvar) | Nor bis-indole compounds usable as medicaments |
| DE2845574A1 (de) | 1978-10-19 | 1980-04-24 | Deutsches Krebsforsch | Durch heterocyclische ringe oder alkylreste substituierte analoga von ccnu und verfahren zu deren herstellung |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| EP0111058B1 (en) | 1982-11-26 | 1987-11-04 | Nippon Kayaku Kabushiki Kaisha | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| US4526988A (en) | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
| JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| SE8405493D0 (sv) | 1984-11-01 | 1984-11-01 | Bror Morein | Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel |
| ATE71303T1 (de) * | 1986-01-14 | 1992-01-15 | Nederlanden Staat | Verfahren zur herstellung immunologischer komplexe und diese enthaltende pharmazeutische zusammensetzung. |
| FR2601676B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
| FR2601675B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US5004758A (en) | 1987-12-01 | 1991-04-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells |
| NZ230747A (en) * | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| JPH0679958B2 (ja) | 1988-10-07 | 1994-10-12 | 東レ株式会社 | 糸条の巻取装置 |
| GB8919819D0 (en) | 1989-09-01 | 1989-10-18 | Coopers Animal Health | Complexes having adjuvant activity |
| NL9002314A (nl) * | 1990-10-23 | 1992-05-18 | Nederlanden Staat | Immunogene complexen, in het bijzonder iscoms. |
| MX9102128A (es) | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
| SE502569C2 (sv) * | 1991-05-31 | 1995-11-13 | British Tech Group | Användning av en immunologiskt inert matris av en sterol och saponiner som kan bilda sfäriska nanopartiklar med snäv storleksfördelning som läkemedelsbärare, partiklar, komposition samt kit |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| ATE255131T1 (de) | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| IT1250692B (it) | 1991-07-23 | 1995-04-21 | Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi. | |
| US5650398A (en) * | 1992-07-02 | 1997-07-22 | Cambridge Biotech Corporation | Drug delivery enhancement via modified saponins |
| US5476932A (en) | 1994-08-26 | 1995-12-19 | Hoffmann-La Roche Inc. | Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives |
| AUPM873294A0 (en) * | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| US20010053365A1 (en) * | 1995-04-25 | 2001-12-20 | Smithkline Beecham Biologicals S.A. | Vaccines |
| SE9600647D0 (sv) | 1996-02-21 | 1996-02-21 | Bror Morein | Ny användning |
| GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| GB9719426D0 (en) | 1997-09-13 | 1997-11-12 | Johnson Matthey Plc | Novel process |
| GB9817052D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| DE59903869D1 (de) * | 1998-10-14 | 2003-01-30 | Cognis Deutschland Gmbh | Verwendung von nanoskaligen sterolen und sterolestern |
| CN1254541C (zh) * | 2000-02-23 | 2006-05-03 | 史密丝克莱恩比彻姆生物有限公司 | 新化合物 |
| DK1377320T3 (da) | 2001-04-04 | 2009-02-09 | Nordic Vaccine Technology As | Polynukleotidbindingskomplekser omfattende steroler og saponiner |
| US7713942B2 (en) * | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
| JP2005500293A (ja) * | 2001-06-15 | 2005-01-06 | コーナーストーン ファーマシューティカルズ | 標的とする組織及び細胞の治療に有用なナノ粒子を含む薬剤組成物及び診断のための組成物 |
| GB0123580D0 (en) * | 2001-10-01 | 2001-11-21 | Glaxosmithkline Biolog Sa | Vaccine |
| EP1465598A4 (en) * | 2001-12-21 | 2006-12-20 | David S Soane | USE OF OLIGOMERS AND POLYMERS FOR THE SOLUBILIZATION, STABILIZATION AND SUPPLY OF MEDICAMENTS |
| US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
| SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
| DK1545605T3 (da) | 2002-10-02 | 2010-04-12 | Nordic Vaccine As | Komposition til vaccination |
| SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
| US20050175623A1 (en) * | 2004-02-10 | 2005-08-11 | Zheng-Pin Wang | Saponins as anticancer agent |
| JP2008539255A (ja) * | 2005-04-26 | 2008-11-13 | マイクロビア インコーポレーテッド | 高コレステロール血症のための4−ビアリーリル−1−フェニルアゼチジン−2−オングルクロニド誘導体 |
| KR100641060B1 (ko) * | 2005-07-22 | 2006-11-01 | 삼성전자주식회사 | 게이트 구조물의 제조 방법 및 이를 이용하는 반도체장치의 제조 방법 |
| DE102006007903A1 (de) | 2005-12-21 | 2007-07-05 | VD-Werkstätten GmbH & Co KG | Verfahren für die Herstellung von Möbel-Formteilen |
| US20100221345A1 (en) * | 2006-01-18 | 2010-09-02 | National University Corporation Tokyo Medical And | Osteogenic biomaterial containing osteogenesis promoting substance and nanogel |
| ES2630205T3 (es) * | 2006-11-20 | 2017-08-18 | Duecom | Uso de partículas que contengan lípidos que comprenden saponínas quillaja para el tratamiento del cáncer |
| WO2008070538A2 (en) * | 2006-12-01 | 2008-06-12 | Anterios, Inc. | Micellar nanoparticles comprising botulinum toxin |
| US8252555B2 (en) * | 2006-12-29 | 2012-08-28 | Evonik Degussa Ag | Nucleic acid encoding a cobalamin-dependent methionine synthase polypeptide |
| US20080299177A1 (en) * | 2007-06-06 | 2008-12-04 | Biovaluation & Analysis, Inc. | Supramolecular Complexes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo |
| CA2917512C (en) * | 2007-10-12 | 2025-08-05 | President And Fellows Of Harvard College | VACCINE NANOTECHNOLOGY |
| JP2011500514A (ja) * | 2007-10-12 | 2011-01-06 | シーエスエル、リミテッド | 汎発流行性インフルエンザウィルスに対する免疫応答を惹起する方法 |
| WO2009156960A2 (en) * | 2008-06-27 | 2009-12-30 | Pfizer Inc. | Novel adjuvant compositions |
| MX2011002267A (es) * | 2008-08-28 | 2011-03-30 | Glaxosmithkline Biolog Sa | Vacuna. |
| JP5344558B2 (ja) * | 2008-10-31 | 2013-11-20 | 国立大学法人 東京医科歯科大学 | カチオン性ナノゲルを用いる粘膜ワクチン |
| MX2012000036A (es) * | 2009-06-24 | 2012-02-28 | Glaxosmithkline Biolog Sa | Vacuna. |
| DK2445526T3 (en) * | 2009-06-24 | 2016-06-27 | Glaxosmithkline Biologicals Sa | Recombinant RSV antigens. |
| CA2766285A1 (en) | 2009-07-10 | 2011-01-13 | Isconova Ab | New composition |
| PT2670432T (pt) * | 2011-02-04 | 2021-05-04 | Zoetis Services Llc | Composições imunogénicas de bordetella bronchiseptica |
| EP2709590A4 (en) * | 2011-05-11 | 2015-05-13 | Nanovalent Pharmaceuticals Inc | REINFORCED GROWTH INHIBITION OF OSTEOSARCOMS THROUGH CYTOTOXIC POLYMERIZED LIPOSOMAL NANOPARTICLES TO AIM AT THE ALCAM CELL SURFACE RECEPTOR |
| JP6050822B2 (ja) | 2011-10-03 | 2016-12-21 | モレインクス,エービー | ナノ粒子、ナノ粒子の調製のための処理、および癌治療および食品関連化合物を含む医療分野における両親媒性分子または疎水性分子ための担体としてのナノ粒子の使用 |
| GB201119999D0 (en) * | 2011-11-20 | 2012-01-04 | Glaxosmithkline Biolog Sa | Vaccine |
| US9907846B2 (en) | 2013-04-01 | 2018-03-06 | Mx Adjuvac Ab | Nanoparticles, composed of sterol and saponin from Quillaja saponaria Molina for use in pharmaceutical compositions |
| US11390483B2 (en) | 2017-10-20 | 2022-07-19 | Corelex Shin-Ei Co., Ltd. | Log roll manufacturing apparatus |
-
2012
- 2012-10-01 JP JP2014534512A patent/JP6050822B2/ja active Active
- 2012-10-01 DK DK17207322.3T patent/DK3311827T3/da active
- 2012-10-01 CN CN201280048961.9A patent/CN103857403B/zh active Active
- 2012-10-01 TR TR2018/08733T patent/TR201808733T4/tr unknown
- 2012-10-01 PT PT127814895T patent/PT2750683T/pt unknown
- 2012-10-01 ES ES12781489T patent/ES2673957T5/es active Active
- 2012-10-01 EP EP22214948.6A patent/EP4176871A1/en not_active Withdrawn
- 2012-10-01 IN IN3485DEN2014 patent/IN2014DN03485A/en unknown
- 2012-10-01 US US14/349,142 patent/US10047116B2/en active Active
- 2012-10-01 EP EP12781489.5A patent/EP2750683B2/en active Active
- 2012-10-01 WO PCT/SE2012/051048 patent/WO2013051994A1/en not_active Ceased
- 2012-10-01 EP EP17207322.3A patent/EP3311827B1/en active Active
- 2012-10-01 RS RS20180720A patent/RS57350B1/sr unknown
- 2012-10-01 AU AU2012319239A patent/AU2012319239B2/en active Active
- 2012-10-01 HR HRP20180956TT patent/HRP20180956T1/hr unknown
- 2012-10-01 KR KR1020147011942A patent/KR102090740B1/ko active Active
- 2012-10-01 DK DK12781489.5T patent/DK2750683T4/da active
- 2012-10-01 CA CA2850296A patent/CA2850296C/en active Active
- 2012-10-01 PL PL12781489T patent/PL2750683T3/pl unknown
-
2014
- 2014-03-24 ZA ZA2014/02040A patent/ZA201402040B/en unknown
-
2017
- 2017-05-25 US US15/605,595 patent/US10100078B2/en active Active
- 2017-11-16 US US15/815,488 patent/US10487107B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Bezbaruah et al. | Nanoparticle-based delivery systems for vaccines | |
| Witika et al. | Current advances in specialised niosomal drug delivery: manufacture, characterization and drug delivery applications | |
| Chountoulesi et al. | Lyotropic liquid crystalline nanostructures as drug delivery systems and vaccine platforms | |
| Duong et al. | Recent advances in intranasal liposomes for drug, gene, and vaccine delivery | |
| Zhang et al. | pH-responsive nanoparticles targeted to lungs for improved therapy of acute lung inflammation/injury | |
| HRP20180956T1 (hr) | Nanočestice, postupak dobivanja i njihova primjena kao nosača amfipatičnih ili hidrofobnih molekula u medicini, uključujući i terapiju karcinoma, kao i prehrambenih spojeva | |
| Kumar et al. | Nanocarriers in tuberculosis treatment: challenges and delivery strategies | |
| Juere et al. | In vitro dissolution, cellular membrane permeability, and anti-inflammatory response of resveratrol-encapsulated mesoporous silica nanoparticles | |
| Colley et al. | Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluation | |
| Binaymotlagh et al. | Liposome–hydrogel composites for controlled drug delivery applications | |
| Elsayed et al. | Design and characterisation of novel Sorafenib-loaded carbon nanotubes with distinct tumour-suppressive activity in hepatocellular carcinoma | |
| Kamboj et al. | Vesicular drug delivery systems: a novel approach for drug targeting | |
| JP2022003102A (ja) | 異なる医薬品の制御送達のためのビヒクル | |
| Praphakar et al. | Targeted delivery of rifampicin to tuberculosis-infected macrophages: design, in-vitro, and in-vivo performance of rifampicin-loaded poly (ester amide) s nanocarriers | |
| Yan et al. | A novel type of aqueous dispersible ultrathin-layered double hydroxide nanosheets for in vivo bioimaging and drug delivery | |
| Kumar et al. | Nanomedicine in drug delivery | |
| Zhao et al. | Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review | |
| Ali et al. | Enhancing the solubility and oral bioavailability of poorly water-soluble drugs using monoolein cubosomes | |
| JP2012517987A5 (ja) | 吸入用の医薬組成物のfpd特性を設定する方法 | |
| CN112074298B (zh) | Langerin+细胞靶向 | |
| JP2015515992A5 (enExample) | ||
| Shi et al. | Optimization of process variables of zanamivir-loaded solid lipid nanoparticles and the prediction of their cellular transport in Caco-2 cell model | |
| HN2011000864A (es) | Particulas inhalables que comprenden tiotropio | |
| Lin et al. | Co-delivery of imiquimod and plasmid DNA via an amphiphilic pH-responsive star polymer that forms unimolecular micelles in water | |
| WO2015079952A1 (ja) | アジュバント組成物およびこれを含むワクチン組成物、並びにこれらの製造方法 |