ATE409495T1 - Polynukleotide-bindende komplexe die sterolen und saponine enthalten - Google Patents
Polynukleotide-bindende komplexe die sterolen und saponine enthaltenInfo
- Publication number
- ATE409495T1 ATE409495T1 AT02759762T AT02759762T ATE409495T1 AT E409495 T1 ATE409495 T1 AT E409495T1 AT 02759762 T AT02759762 T AT 02759762T AT 02759762 T AT02759762 T AT 02759762T AT E409495 T1 ATE409495 T1 AT E409495T1
- Authority
- AT
- Austria
- Prior art keywords
- complexes
- saponins
- methods
- determinant
- polynucleotide binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200100560 | 2001-04-04 | ||
US30860901P | 2001-07-31 | 2001-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE409495T1 true ATE409495T1 (de) | 2008-10-15 |
Family
ID=26069002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02759762T ATE409495T1 (de) | 2001-04-04 | 2002-04-04 | Polynukleotide-bindende komplexe die sterolen und saponine enthalten |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP2011517A1 (de) |
JP (2) | JP2004528321A (de) |
AT (1) | ATE409495T1 (de) |
DE (1) | DE60229118D1 (de) |
DK (1) | DK1377320T3 (de) |
NZ (1) | NZ529347A (de) |
WO (1) | WO2002080981A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006503072A (ja) * | 2002-10-02 | 2006-01-26 | ノルディック ワクチン テクノロジー アクティーゼルスカブ | ワクチン接種用組成物 |
WO2009106085A1 (en) * | 2008-02-28 | 2009-09-03 | Nordic Vaccine A/S | Vaccine compositions comprising saccharide antigens |
AU2012319239B2 (en) | 2011-10-03 | 2017-04-20 | Mx Adjuvac Ab | Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrophobic molecules in fields of medicine including cancer treatment and food related compounds |
US9907846B2 (en) | 2013-04-01 | 2018-03-06 | Mx Adjuvac Ab | Nanoparticles, composed of sterol and saponin from Quillaja saponaria Molina for use in pharmaceutical compositions |
EP3652190B1 (de) | 2017-07-11 | 2023-06-14 | Freie Universität Berlin | Neuartige verwendungen eines saponins und verfahren zu dessen isolierung |
CN108498376B (zh) * | 2018-04-02 | 2020-11-13 | 榛硕(武汉)智能科技有限公司 | 一种甲基硅油乳液及其制备方法 |
CN109295080B (zh) * | 2018-09-19 | 2021-08-20 | 昆明理工大学 | 珠子参β-香树脂醇合成酶基因Pjβ-AS的用途 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4162282A (en) | 1976-04-22 | 1979-07-24 | Coulter Electronics, Inc. | Method for producing uniform particles |
GB2064320B (en) | 1979-10-13 | 1983-10-12 | Welsh Nat School Med | Intra-ocular irrigation fluid |
US4310505A (en) | 1979-11-08 | 1982-01-12 | California Institute Of Technology | Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances |
US4533254A (en) | 1981-04-17 | 1985-08-06 | Biotechnology Development Corporation | Apparatus for forming emulsions |
US4443432A (en) | 1981-10-05 | 1984-04-17 | Alcon Laboratories, Inc. | Ophthmalic irrigating solution |
US4550022A (en) | 1981-10-05 | 1985-10-29 | Alcon Laboratories, Inc. | Tissue irrigating solution |
US4526714A (en) | 1982-12-13 | 1985-07-02 | Cordis Europa N.V. | Conjugates of anticoagulant and protein |
SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
SE450674B (sv) | 1982-11-17 | 1987-07-13 | Volvo Ab | Kabelholje |
US4728575A (en) | 1984-04-27 | 1988-03-01 | Vestar, Inc. | Contrast agents for NMR imaging |
CA1264668A (en) | 1984-06-20 | 1990-01-23 | Pieter R. Cullis | Extrusion techniques for producing liposomes |
US4921706A (en) | 1984-11-20 | 1990-05-01 | Massachusetts Institute Of Technology | Unilamellar lipid vesicles and method for their formation |
NZ217844A (en) | 1985-10-11 | 1989-10-27 | Sumitomo Pharma | A sustained release pharmaceutical composition containing silicone elastomer and an albumin |
US4737323A (en) | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
IL79559A0 (en) | 1986-07-29 | 1986-10-31 | Univ Ramot | Contrast agents for nmr medical imaging |
US4728578A (en) | 1986-08-13 | 1988-03-01 | The Lubrizol Corporation | Compositions containing basic metal salts and/or non-Newtonian colloidal disperse systems and vinyl aromatic containing polymers |
US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
US4938970A (en) | 1987-02-06 | 1990-07-03 | Hustead Robert E | Painless electrolyte solutions |
US5583112A (en) | 1987-05-29 | 1996-12-10 | Cambridge Biotech Corporation | Saponin-antigen conjugates and the use thereof |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
EP0442962B1 (de) | 1988-11-09 | 1994-01-05 | UNGER, Evan C | Liposomale radiologische kontrastmittel |
FR2645866B1 (fr) | 1989-04-17 | 1991-07-05 | Centre Nat Rech Scient | Nouvelles lipopolyamines, leur preparation et leur emploi |
AU651319B2 (en) | 1989-07-27 | 1994-07-21 | Univax Biologics Incorporated | Lipid A analog/immunogenic carrier conjugates and the use thereof as vaccines |
NL9002314A (nl) | 1990-10-23 | 1992-05-18 | Nederlanden Staat | Immunogene complexen, in het bijzonder iscoms. |
GB9106673D0 (en) | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
JPH06507904A (ja) | 1991-05-23 | 1994-09-08 | イマアーレクス・フアーマシユーチカル・コーポレーシヨン | 磁気共鳴画像形成用の油脂可溶化合物 |
SE502569C2 (sv) * | 1991-05-31 | 1995-11-13 | British Tech Group | Användning av en immunologiskt inert matris av en sterol och saponiner som kan bilda sfäriska nanopartiklar med snäv storleksfördelning som läkemedelsbärare, partiklar, komposition samt kit |
US5273965A (en) | 1992-07-02 | 1993-12-28 | Cambridge Biotech Corporation | Methods for enhancing drug delivery with modified saponins |
US5650398A (en) | 1992-07-02 | 1997-07-22 | Cambridge Biotech Corporation | Drug delivery enhancement via modified saponins |
WO1995009179A1 (en) | 1993-09-30 | 1995-04-06 | Seed Capital Investments (Sci) B.V. | Compounds with adjuvant activity |
AU2112697A (en) * | 1996-02-09 | 1997-08-28 | Pi-Wan Cheng | Receptor ligand-facilitated delivery of biologically active molecules |
CA2260761C (en) | 1996-06-25 | 2011-05-03 | Nico Johannes Christiaan Maria Beekman | Vaccine comprising antigens bound to carriers through labile bonds |
JP3963506B2 (ja) * | 1996-08-26 | 2007-08-22 | 俊彦 松尾 | リポソーム点眼剤 |
AUPO517897A0 (en) * | 1997-02-19 | 1997-04-11 | Csl Limited | Chelating immunostimulating complexes |
US6120751A (en) | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
EP0979100A1 (de) * | 1997-04-30 | 2000-02-16 | Merieux OraVax SNC | Anti-helicobacter impfstoffzusammensetzung die ein th1 - typ adjuvans enthält |
US6080725A (en) | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
AUPO732997A0 (en) * | 1997-06-12 | 1997-07-03 | Csl Limited | Ganglioside immunostimulating complexes and uses thereof |
DE19740092A1 (de) * | 1997-09-12 | 1999-03-18 | Ulrich Dr Med Hengge | Liposomen und Verfahren zur Transfektion von Zellen |
US6013258A (en) * | 1997-10-09 | 2000-01-11 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
US7491409B1 (en) * | 1999-03-02 | 2009-02-17 | Transave, Inc. | Encapsulation of bioactive complexes in liposomes |
EP1292330A1 (de) | 2000-03-31 | 2003-03-19 | Vaccine Chip Technology APS | Immunostimulierende eigenschaften eines tgf-beta-fragmentes |
-
2002
- 2002-04-04 NZ NZ529347A patent/NZ529347A/en unknown
- 2002-04-04 EP EP08159646A patent/EP2011517A1/de not_active Withdrawn
- 2002-04-04 WO PCT/DK2002/000229 patent/WO2002080981A2/en active IP Right Grant
- 2002-04-04 AT AT02759762T patent/ATE409495T1/de not_active IP Right Cessation
- 2002-04-04 DE DE60229118T patent/DE60229118D1/de not_active Expired - Lifetime
- 2002-04-04 EP EP02759762A patent/EP1377320B1/de not_active Expired - Lifetime
- 2002-04-04 JP JP2002579019A patent/JP2004528321A/ja not_active Withdrawn
- 2002-04-04 DK DK02759762T patent/DK1377320T3/da active
-
2010
- 2010-05-26 JP JP2010120290A patent/JP2010180249A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE60229118D1 (de) | 2008-11-13 |
EP2011517A1 (de) | 2009-01-07 |
DK1377320T3 (da) | 2009-02-09 |
JP2004528321A (ja) | 2004-09-16 |
WO2002080981A2 (en) | 2002-10-17 |
EP1377320A2 (de) | 2004-01-07 |
NZ529347A (en) | 2008-01-31 |
EP1377320B1 (de) | 2008-10-01 |
JP2010180249A (ja) | 2010-08-19 |
WO2002080981A3 (en) | 2002-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |