JP2014530018A5 - - Google Patents
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- Publication number
- JP2014530018A5 JP2014530018A5 JP2014534483A JP2014534483A JP2014530018A5 JP 2014530018 A5 JP2014530018 A5 JP 2014530018A5 JP 2014534483 A JP2014534483 A JP 2014534483A JP 2014534483 A JP2014534483 A JP 2014534483A JP 2014530018 A5 JP2014530018 A5 JP 2014530018A5
- Authority
- JP
- Japan
- Prior art keywords
- facviia
- facvii
- derivative
- conjugate
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20110102099 | 2011-10-06 | ||
| KR10-2011-0102099 | 2011-10-06 | ||
| PCT/KR2012/008102 WO2013051900A2 (en) | 2011-10-06 | 2012-10-05 | Blood coagulation factor ⅶ and ⅶa derivatives, conjugates and complexes comprising the same, and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014530018A JP2014530018A (ja) | 2014-11-17 |
| JP2014530018A5 true JP2014530018A5 (enExample) | 2015-11-26 |
| JP6108630B2 JP6108630B2 (ja) | 2017-04-05 |
Family
ID=48044320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014534483A Expired - Fee Related JP6108630B2 (ja) | 2011-10-06 | 2012-10-05 | 血液凝固因子ＶＩＩ及びＶＩＩａ誘導体、それらを含む結合体及び複合体、並びにそれらの使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9597378B2 (enExample) |
| EP (2) | EP2763693A4 (enExample) |
| JP (1) | JP6108630B2 (enExample) |
| KR (1) | KR20130037659A (enExample) |
| CN (1) | CN103974716B (enExample) |
| AR (1) | AR088267A1 (enExample) |
| AU (1) | AU2012319308B2 (enExample) |
| BR (1) | BR112014008224A2 (enExample) |
| CA (1) | CA2851223A1 (enExample) |
| IL (1) | IL231930A0 (enExample) |
| MX (1) | MX354493B (enExample) |
| MY (1) | MY168754A (enExample) |
| PH (1) | PH12014500735A1 (enExample) |
| RU (1) | RU2620072C2 (enExample) |
| SG (1) | SG11201401205UA (enExample) |
| TW (1) | TWI565715B (enExample) |
| WO (1) | WO2013051900A2 (enExample) |
| ZA (1) | ZA201402745B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130049671A (ko) | 2011-11-04 | 2013-05-14 | 한미사이언스 주식회사 | 생리활성 폴리펩타이드 결합체 제조 방법 |
| AR090281A1 (es) | 2012-03-08 | 2014-10-29 | Hanmi Science Co Ltd | Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo |
| TWI641382B (zh) * | 2013-01-31 | 2018-11-21 | 韓美藥品股份有限公司 | 於包含因子ｖｉｉ之組成物中使病毒失活之方法 |
| CN103599527A (zh) * | 2013-08-16 | 2014-02-26 | 安源生物科技(上海)有限公司 | 包含改良型人凝血因子FVII-Fc融合蛋白的药物组合物 |
| CN104774269B (zh) * | 2013-08-16 | 2016-02-24 | 安源生物科技(上海)有限公司 | 改良型人凝血因子FVII-Fc融合蛋白及其制备方法与用途 |
| KR20150026024A (ko) * | 2013-08-30 | 2015-03-11 | 한미약품 주식회사 | 인간 혈액응고 7인자 유도체의 대량 생산 방법 |
| DK3127923T3 (da) * | 2014-03-31 | 2021-11-22 | Hanmi Pharm Ind Co Ltd | Fremgangsmåde til forbedring af oppløselighed af protein og peptid ved hjælp af immunoglobulin-fc-fragment-binding |
| EP3373926B1 (en) | 2015-11-10 | 2020-06-10 | Sun Chemical Corporation | Alkoxylated dispersing agents |
| KR102041671B1 (ko) * | 2017-05-08 | 2019-11-28 | 가톨릭대학교 산학협력단 | β-아밀로이드 단백질의 응집을 억제하는 생체친화적 펩타이드 |
| KR20190086269A (ko) * | 2018-01-12 | 2019-07-22 | 재단법인 목암생명과학연구소 | 체내 지속형 재조합 당단백질 및 이의 제조방법 |
| WO2019240881A2 (en) * | 2018-04-23 | 2019-12-19 | Emory University | Vip and vip agonists, nanoparticles, and uses in inflammatory t-cell mediated disease |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001058935A2 (en) * | 2000-02-11 | 2001-08-16 | Maxygen Aps | FACTOR VII OR VIIa-LIKE MOLECULES |
| WO2002077218A1 (en) | 2001-03-22 | 2002-10-03 | Novo Nordisk Health Care Ag | Coagulation factor vii derivatives |
| US7235638B2 (en) * | 2001-03-22 | 2007-06-26 | Novo Nordisk Healthcare A/G | Coagulation factor VII derivatives |
| AU2003242507A1 (en) * | 2002-07-12 | 2004-02-02 | Novo Nordisk A/S | A tissue factor binding immunoconjugate comprising factor viia |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| JP2007509843A (ja) | 2003-10-07 | 2007-04-19 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 第ＶＩＩ／ＶＩＩａ因子活性を有するハイブリッド分子 |
| BRPI0406606A (pt) | 2003-11-13 | 2005-12-06 | Hanmi Pharm Ind Co Ltd | Composição farmacêutica compreendendo uma região fc de imunoglobulina como um veìculo |
| ES2434032T3 (es) * | 2005-06-17 | 2013-12-13 | Novo Nordisk Health Care Ag | Compuestos de FVIIA diméricos y multiméricos |
| US8476234B2 (en) * | 2006-02-03 | 2013-07-02 | Prolor Biotech Inc. | Long-acting coagulation factors and methods of producing same |
| EP1816201A1 (en) * | 2006-02-06 | 2007-08-08 | CSL Behring GmbH | Modified coagulation factor VIIa with extended half-life |
| US7939632B2 (en) * | 2006-06-14 | 2011-05-10 | Csl Behring Gmbh | Proteolytically cleavable fusion proteins with high molar specific activity |
| EP2032607B2 (en) | 2006-06-14 | 2017-02-22 | CSL Behring GmbH | Proteolytically cleavable fusion protein comprising a blood coagulation factor |
| KR100880509B1 (ko) | 2006-10-16 | 2009-01-28 | 한미약품 주식회사 | 재조합 단백질의 대량 생산을 위한 신규한 벡터, 발현세포주 및 이를 이용한 재조합 단백질의 생산 방법 |
| KR101104684B1 (ko) | 2008-12-02 | 2012-01-16 | 이화여자대학교 산학협력단 | 관찰 방향 및 조명을 고려한 피부 질감 렌더링 방법 및 그 장치 |
| US20120121613A1 (en) * | 2009-01-19 | 2012-05-17 | Bayer Healthcare Llc | Protein conjugate having an endopeptidase- cleavable bioprotective moiety |
-
2012
- 2012-10-05 CA CA2851223A patent/CA2851223A1/en not_active Abandoned
- 2012-10-05 PH PH1/2014/500735A patent/PH12014500735A1/en unknown
- 2012-10-05 MY MYPI2014000988A patent/MY168754A/en unknown
- 2012-10-05 JP JP2014534483A patent/JP6108630B2/ja not_active Expired - Fee Related
- 2012-10-05 EP EP12838228.0A patent/EP2763693A4/en not_active Withdrawn
- 2012-10-05 WO PCT/KR2012/008102 patent/WO2013051900A2/en not_active Ceased
- 2012-10-05 MX MX2014004099A patent/MX354493B/es active IP Right Grant
- 2012-10-05 AU AU2012319308A patent/AU2012319308B2/en not_active Ceased
- 2012-10-05 AR ARP120103742A patent/AR088267A1/es unknown
- 2012-10-05 EP EP18183149.6A patent/EP3417881A1/en not_active Withdrawn
- 2012-10-05 CN CN201280060378.XA patent/CN103974716B/zh not_active Expired - Fee Related
- 2012-10-05 RU RU2014115291A patent/RU2620072C2/ru not_active IP Right Cessation
- 2012-10-05 BR BR112014008224A patent/BR112014008224A2/pt not_active Application Discontinuation
- 2012-10-05 US US14/349,925 patent/US9597378B2/en not_active Expired - Fee Related
- 2012-10-05 TW TW101136851A patent/TWI565715B/zh not_active IP Right Cessation
- 2012-10-05 SG SG11201401205UA patent/SG11201401205UA/en unknown
- 2012-10-08 KR KR1020120111537A patent/KR20130037659A/ko not_active Abandoned
-
2014
- 2014-04-03 IL IL231930A patent/IL231930A0/en unknown
- 2014-04-15 ZA ZA2014/02745A patent/ZA201402745B/en unknown
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