DK3127923T3 - Fremgangsmåde til forbedring af oppløselighed af protein og peptid ved hjælp af immunoglobulin-fc-fragment-binding - Google Patents
Fremgangsmåde til forbedring af oppløselighed af protein og peptid ved hjælp af immunoglobulin-fc-fragment-binding Download PDFInfo
- Publication number
- DK3127923T3 DK3127923T3 DK15772562.3T DK15772562T DK3127923T3 DK 3127923 T3 DK3127923 T3 DK 3127923T3 DK 15772562 T DK15772562 T DK 15772562T DK 3127923 T3 DK3127923 T3 DK 3127923T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptime
- immunoglobulin
- solubility
- procedure
- improving protein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20140038032 | 2014-03-31 | ||
PCT/KR2015/003195 WO2015152618A1 (ko) | 2014-03-31 | 2015-03-31 | 면역글로불린 fc 단편 결합을 이용한 단백질 및 펩타이드의 용해도를 개선시키는 방법 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3127923T3 true DK3127923T3 (da) | 2021-11-22 |
Family
ID=54240858
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15772562.3T DK3127923T3 (da) | 2014-03-31 | 2015-03-31 | Fremgangsmåde til forbedring af oppløselighed af protein og peptid ved hjælp af immunoglobulin-fc-fragment-binding |
Country Status (21)
Country | Link |
---|---|
US (2) | US20170128589A1 (da) |
EP (2) | EP3889185A3 (da) |
JP (3) | JP2017511335A (da) |
KR (2) | KR102385120B1 (da) |
CN (2) | CN117065044A (da) |
AU (1) | AU2015242657B2 (da) |
CA (1) | CA2944138C (da) |
DK (1) | DK3127923T3 (da) |
EA (1) | EA201691795A1 (da) |
ES (1) | ES2897935T3 (da) |
HU (1) | HU231358B1 (da) |
IL (1) | IL248111B (da) |
MX (1) | MX2016012788A (da) |
MY (1) | MY192248A (da) |
NO (1) | NO20161667A1 (da) |
PH (1) | PH12016501937A1 (da) |
PL (1) | PL3127923T3 (da) |
SG (2) | SG10202107752PA (da) |
UA (1) | UA124182C2 (da) |
WO (1) | WO2015152618A1 (da) |
ZA (1) | ZA201607344B (da) |
Families Citing this family (14)
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EP3889185A3 (en) * | 2014-03-31 | 2022-01-26 | Hanmi Pharm. Co., Ltd. | Composition for improving the solubility of a protein or peptide by using immunoglobulin fc fragment linkage |
EP3384935A4 (en) * | 2015-12-02 | 2019-08-21 | Hanmi Pharm. Co., Ltd. | PROTEIN COMPLEX UTILIZING A FATTY ACID DERIVATIVE, AND PROCESS FOR PREPARING THE SAME |
JP2020506932A (ja) * | 2017-02-03 | 2020-03-05 | ハンミ ファーマシューティカル カンパニー リミテッド | 持続性が増加した生理活性物質の結合体及びその用途 |
CN106892978A (zh) * | 2017-04-18 | 2017-06-27 | 天津世传生物科技有限公司 | 复合物、蛋白质及二者的制备方法 |
EP3641782A4 (en) * | 2017-06-20 | 2021-03-24 | Madrigal Pharmaceuticals, Inc. | COMBINED THERAPIES INCLUDING TARGETED THERAPEUTICS |
KR102053009B1 (ko) * | 2018-09-19 | 2019-12-09 | 주식회사 바이오앱 | 돼지 열병 백신용 조성물 및 이의 제조 방법 |
KR102250576B1 (ko) | 2018-11-15 | 2021-05-12 | 주식회사 바이오앱 | 식물 발현 시스템에서 캡시드 단백질의 발현을 증가시키는 재조합 벡터 및 이를 이용한 바이러스-유사 입자의 제조방법 |
WO2020101187A1 (ko) | 2018-11-15 | 2020-05-22 | 주식회사 바이오앱 | 식물체에서 바이러스-유사 입자를 발현하는 재조합 벡터 및 이를 이용한 써코바이러스-유사 입자를 포함하는 백신 조성물의 제조방법 |
KR102288367B1 (ko) | 2018-11-15 | 2021-08-11 | 주식회사 바이오앱 | 식물체에서 바이러스-유사 입자를 발현하는 재조합 벡터 및 이를 이용한 써코바이러스-유사 입자를 포함하는 백신 조성물의 제조방법 |
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KR102450007B1 (ko) * | 2020-10-16 | 2022-10-04 | 주식회사 아이엠바이오로직스 | IgM 영역을 이용한 융합단백질 플랫폼 |
KR20220122815A (ko) | 2021-02-25 | 2022-09-05 | 주식회사 바이오앱 | 식물 발현 시스템을 이용한 알팔파 모자이크 바이러스 유사 입자 제조 방법 및 이의 활용 |
KR20240027904A (ko) | 2022-08-22 | 2024-03-05 | (주) 에빅스젠 | 용해도 개선용 펩티드 및 이를 포함하는 용해도 개선 조성물 |
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EP3889185A3 (en) * | 2014-03-31 | 2022-01-26 | Hanmi Pharm. Co., Ltd. | Composition for improving the solubility of a protein or peptide by using immunoglobulin fc fragment linkage |
TWI684458B (zh) * | 2014-05-30 | 2020-02-11 | 南韓商韓美藥品股份有限公司 | 包含胰島素及glp-1/昇糖素雙重促效劑之治療糖尿病之組成物 |
KR20150140177A (ko) * | 2014-06-05 | 2015-12-15 | 한미약품 주식회사 | 단백질 및 펩타이드의 면역원성을 감소시키는 방법 |
BR112018013530A2 (pt) * | 2015-12-31 | 2018-12-04 | Hanmi Pharm. Co., Ltd. | ?peptídeo isolado, polinucleotídeo e composição farmacêutica? |
JP7208020B2 (ja) * | 2016-06-29 | 2023-01-18 | ハンミ ファーマシューティカル カンパニー リミテッド | グルカゴン誘導体、その結合体、及びそれを含む組成物、並びにその治療的用途 |
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2015
- 2015-03-31 EP EP21169291.8A patent/EP3889185A3/en active Pending
- 2015-03-31 EA EA201691795A patent/EA201691795A1/ru unknown
- 2015-03-31 SG SG10202107752PA patent/SG10202107752PA/en unknown
- 2015-03-31 ES ES15772562T patent/ES2897935T3/es active Active
- 2015-03-31 PL PL15772562T patent/PL3127923T3/pl unknown
- 2015-03-31 WO PCT/KR2015/003195 patent/WO2015152618A1/ko active Application Filing
- 2015-03-31 MY MYPI2016703516A patent/MY192248A/en unknown
- 2015-03-31 US US15/129,897 patent/US20170128589A1/en not_active Abandoned
- 2015-03-31 JP JP2016560523A patent/JP2017511335A/ja active Pending
- 2015-03-31 CN CN202310720671.4A patent/CN117065044A/zh active Pending
- 2015-03-31 EP EP15772562.3A patent/EP3127923B1/en active Active
- 2015-03-31 DK DK15772562.3T patent/DK3127923T3/da active
- 2015-03-31 CN CN201580028749.XA patent/CN106488933A/zh active Pending
- 2015-03-31 SG SG11201608120TA patent/SG11201608120TA/en unknown
- 2015-03-31 AU AU2015242657A patent/AU2015242657B2/en active Active
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- 2015-03-31 CA CA2944138A patent/CA2944138C/en active Active
- 2015-03-31 UA UAA201610351A patent/UA124182C2/uk unknown
- 2015-03-31 KR KR1020150045621A patent/KR102385120B1/ko active IP Right Grant
- 2015-03-31 HU HUP1600621A patent/HU231358B1/hu unknown
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2016
- 2016-09-28 IL IL248111A patent/IL248111B/en unknown
- 2016-09-29 PH PH12016501937A patent/PH12016501937A1/en unknown
- 2016-10-19 NO NO20161667A patent/NO20161667A1/en unknown
- 2016-10-25 ZA ZA2016/07344A patent/ZA201607344B/en unknown
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2019
- 2019-11-25 JP JP2019212180A patent/JP7333249B2/ja active Active
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2021
- 2021-07-26 JP JP2021121272A patent/JP7322105B2/ja active Active
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2022
- 2022-03-22 KR KR1020220035314A patent/KR20220042326A/ko not_active Application Discontinuation
- 2022-06-13 US US17/839,053 patent/US20230220034A1/en active Pending
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