JP2014519506A5 - - Google Patents
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- Publication number
- JP2014519506A5 JP2014519506A5 JP2014513796A JP2014513796A JP2014519506A5 JP 2014519506 A5 JP2014519506 A5 JP 2014519506A5 JP 2014513796 A JP2014513796 A JP 2014513796A JP 2014513796 A JP2014513796 A JP 2014513796A JP 2014519506 A5 JP2014519506 A5 JP 2014519506A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- rfurin
- ppm
- sugar
- nonionic surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492712P | 2011-06-02 | 2011-06-02 | |
| US61/492,712 | 2011-06-02 | ||
| PCT/US2012/040790 WO2012167271A1 (en) | 2011-06-02 | 2012-06-04 | Formulations of recombinant furin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015161719A Division JP6064007B2 (ja) | 2011-06-02 | 2015-08-19 | 組換えフューリン製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014519506A JP2014519506A (ja) | 2014-08-14 |
| JP2014519506A5 true JP2014519506A5 (https=) | 2015-07-30 |
| JP5797837B2 JP5797837B2 (ja) | 2015-10-21 |
Family
ID=46705014
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014513796A Expired - Fee Related JP5797837B2 (ja) | 2011-06-02 | 2012-06-04 | 組換えフューリン製剤 |
| JP2015161719A Expired - Fee Related JP6064007B2 (ja) | 2011-06-02 | 2015-08-19 | 組換えフューリン製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015161719A Expired - Fee Related JP6064007B2 (ja) | 2011-06-02 | 2015-08-19 | 組換えフューリン製剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8877473B2 (https=) |
| EP (1) | EP2714087B1 (https=) |
| JP (2) | JP5797837B2 (https=) |
| KR (1) | KR102050609B1 (https=) |
| CN (1) | CN103889454B (https=) |
| AR (1) | AR086672A1 (https=) |
| AU (2) | AU2012261813B2 (https=) |
| BR (1) | BR112013030880B1 (https=) |
| CA (1) | CA2837948C (https=) |
| ES (1) | ES2715289T3 (https=) |
| RU (1) | RU2610436C2 (https=) |
| SG (2) | SG195261A1 (https=) |
| TW (1) | TWI586802B (https=) |
| WO (1) | WO2012167271A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9664608B2 (en) * | 2013-08-20 | 2017-05-30 | Advanced Polymer Monitoring Technologies, Inc. | Characterization of polymer and colloid solutions |
| TWI743023B (zh) | 2014-05-21 | 2021-10-21 | 日商Km生物醫藥股份有限公司 | 基質金屬蛋白酶 7(mmp-7)聚集體之單體化方法 |
| AR102048A1 (es) | 2014-08-12 | 2017-02-01 | Baxalta Inc | Producción del factor x completamente procesado y funcional en un sistema de expresión de mamífero de secreción de furina |
| EP3642225A1 (en) | 2017-06-23 | 2020-04-29 | Baxalta Incorporated | Purification of factor viii subspecies |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL9000917A (nl) | 1989-10-25 | 1991-05-16 | Holland Biotechnology | Farmaceutisch preparaat met endoproteolytische activiteit; werkwijze voor endoproteolytische processing van (precursor) eiwitten en voor de (micro) biologische bereiding van eiwitten. |
| JP4236698B2 (ja) | 1990-11-26 | 2009-03-11 | ジェネティックス インスティチュート,リミテッド ライアビリティ カンパニー | 宿主細胞でのpaceの発現およびその使用法 |
| ZA965368B (en) * | 1995-07-14 | 1997-01-14 | Novo Nordisk As | A pharmaceutical formulation |
| AT404838B (de) | 1995-11-24 | 1999-03-25 | Immuno Ag | Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen |
| US5876992A (en) * | 1996-07-03 | 1999-03-02 | Molecular Biology Resources, Inc. | Method and formulation for stabilization of enzymes |
| US6596526B1 (en) | 2000-06-09 | 2003-07-22 | Baxter Aktiengesellschaft | Furin polypeptides with improved characteristics |
| US7033991B2 (en) * | 2001-07-16 | 2006-04-25 | Board Of Supervisors Of Louisiana State University And Agriculture And Mechanical College | Inhibiting furin with polybasic peptides |
| RU2373953C2 (ru) * | 2003-12-19 | 2009-11-27 | Ново Нордиск Хелс Кеа Аг | Стабилизированная композиция, содержащая полипептид фактора vii |
| DE102006008613A1 (de) * | 2006-02-24 | 2007-08-30 | Dade Behring Marburg Gmbh | Stabilisierte Zubereitungen von Serin-Endopeptidasen, deren Herstellung und Verwendung |
| KR101660533B1 (ko) | 2007-05-22 | 2016-10-10 | 박스알타 인코퍼레이티드 | 인간 푸린의 분취 정제 방법 |
| ES2735173T3 (es) * | 2007-12-31 | 2019-12-16 | Baxalta GmbH | Furina recombinante sustancialmente libre de proteína animal y métodos para producir la misma |
-
2012
- 2012-06-04 CA CA2837948A patent/CA2837948C/en active Active
- 2012-06-04 TW TW101119927A patent/TWI586802B/zh not_active IP Right Cessation
- 2012-06-04 CN CN201280038218.5A patent/CN103889454B/zh active Active
- 2012-06-04 RU RU2013157927A patent/RU2610436C2/ru active
- 2012-06-04 WO PCT/US2012/040790 patent/WO2012167271A1/en not_active Ceased
- 2012-06-04 AU AU2012261813A patent/AU2012261813B2/en not_active Ceased
- 2012-06-04 BR BR112013030880-0A patent/BR112013030880B1/pt not_active IP Right Cessation
- 2012-06-04 EP EP12748588.6A patent/EP2714087B1/en active Active
- 2012-06-04 US US13/488,324 patent/US8877473B2/en active Active
- 2012-06-04 JP JP2014513796A patent/JP5797837B2/ja not_active Expired - Fee Related
- 2012-06-04 SG SG2013089115A patent/SG195261A1/en unknown
- 2012-06-04 SG SG10201604488TA patent/SG10201604488TA/en unknown
- 2012-06-04 AR ARP120101976A patent/AR086672A1/es not_active Application Discontinuation
- 2012-06-04 KR KR1020147000019A patent/KR102050609B1/ko not_active Expired - Fee Related
- 2012-06-04 ES ES12748588T patent/ES2715289T3/es active Active
-
2014
- 2014-09-25 US US14/497,202 patent/US9662376B2/en not_active Expired - Fee Related
-
2015
- 2015-08-19 JP JP2015161719A patent/JP6064007B2/ja not_active Expired - Fee Related
-
2017
- 2017-03-28 AU AU2017202050A patent/AU2017202050A1/en not_active Abandoned
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