JP2014518211A5 - - Google Patents
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- Publication number
- JP2014518211A5 JP2014518211A5 JP2014515930A JP2014515930A JP2014518211A5 JP 2014518211 A5 JP2014518211 A5 JP 2014518211A5 JP 2014515930 A JP2014515930 A JP 2014515930A JP 2014515930 A JP2014515930 A JP 2014515930A JP 2014518211 A5 JP2014518211 A5 JP 2014518211A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- peptide
- item
- angioedema
- induced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 31
- 239000000203 mixture Substances 0.000 claims description 30
- 208000028185 Angioedema Diseases 0.000 claims description 18
- 239000013566 allergen Substances 0.000 claims description 10
- 230000009269 systemic vascular permeability Effects 0.000 claims description 10
- 208000011580 syndromic disease Diseases 0.000 claims description 9
- 206010002198 Anaphylactic reaction Diseases 0.000 claims description 8
- 208000004852 Lung Injury Diseases 0.000 claims description 8
- 206010069363 Traumatic lung injury Diseases 0.000 claims description 8
- 208000003455 anaphylaxis Diseases 0.000 claims description 8
- 208000006673 asthma Diseases 0.000 claims description 8
- 231100000515 lung injury Toxicity 0.000 claims description 8
- 206010028735 Nasal congestion Diseases 0.000 claims description 7
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 230000000172 allergic effect Effects 0.000 claims description 4
- 230000036783 anaphylactic response Effects 0.000 claims description 4
- 208000010668 atopic eczema Diseases 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 4
- 239000012634 fragment Substances 0.000 claims description 4
- MCYTYTUNNNZWOK-LCLOTLQISA-N penetratin Chemical compound C([C@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCNC(N)=N)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CC=CC=C1 MCYTYTUNNNZWOK-LCLOTLQISA-N 0.000 claims description 4
- 206010039085 Rhinitis allergic Diseases 0.000 claims description 3
- 241000700605 Viruses Species 0.000 claims description 3
- 201000010105 allergic rhinitis Diseases 0.000 claims description 3
- 239000000994 contrast dye Substances 0.000 claims description 3
- 239000002085 irritant Substances 0.000 claims description 3
- 231100000021 irritant Toxicity 0.000 claims description 3
- 208000037916 non-allergic rhinitis Diseases 0.000 claims description 3
- 230000000241 respiratory effect Effects 0.000 claims description 3
- 206010003402 Arthropod sting Diseases 0.000 claims description 2
- 208000037487 Endotoxemia Diseases 0.000 claims description 2
- 208000004262 Food Hypersensitivity Diseases 0.000 claims description 2
- 206010016946 Food allergy Diseases 0.000 claims description 2
- 206010061218 Inflammation Diseases 0.000 claims description 2
- 108010002350 Interleukin-2 Proteins 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 claims description 2
- 206010030113 Oedema Diseases 0.000 claims description 2
- 230000001154 acute effect Effects 0.000 claims description 2
- 201000009961 allergic asthma Diseases 0.000 claims description 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 2
- 201000011510 cancer Diseases 0.000 claims description 2
- 230000001684 chronic effect Effects 0.000 claims description 2
- 230000000295 complement effect Effects 0.000 claims description 2
- 230000007812 deficiency Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 235000020932 food allergy Nutrition 0.000 claims description 2
- 238000003384 imaging method Methods 0.000 claims description 2
- 230000004054 inflammatory process Effects 0.000 claims description 2
- 238000001802 infusion Methods 0.000 claims description 2
- 239000003112 inhibitor Substances 0.000 claims description 2
- 238000002347 injection Methods 0.000 claims description 2
- 239000007924 injection Substances 0.000 claims description 2
- 208000014674 injury Diseases 0.000 claims description 2
- 230000001404 mediated effect Effects 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 239000002574 poison Substances 0.000 claims description 2
- 231100000614 poison Toxicity 0.000 claims description 2
- 230000009885 systemic effect Effects 0.000 claims description 2
- 230000008733 trauma Effects 0.000 claims description 2
- 230000002792 vascular Effects 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 24
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161496409P | 2011-06-13 | 2011-06-13 | |
| US61/496,409 | 2011-06-13 | ||
| PCT/US2012/042118 WO2012174028A2 (en) | 2011-06-13 | 2012-06-13 | Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014518211A JP2014518211A (ja) | 2014-07-28 |
| JP2014518211A5 true JP2014518211A5 (enExample) | 2015-06-18 |
| JP6042425B2 JP6042425B2 (ja) | 2016-12-14 |
Family
ID=47357694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014515930A Expired - Fee Related JP6042425B2 (ja) | 2011-06-13 | 2012-06-13 | 肺傷害、喘息、アナフィラキシー、血管性浮腫、全身性血管透過性症候群および鼻閉を処置するためのペプチド組成物および方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9248198B2 (enExample) |
| EP (1) | EP2717897B1 (enExample) |
| JP (1) | JP6042425B2 (enExample) |
| KR (1) | KR102042015B1 (enExample) |
| CN (2) | CN103608026B (enExample) |
| AU (1) | AU2012271781C1 (enExample) |
| BR (1) | BR112013032108B1 (enExample) |
| CA (1) | CA2838662C (enExample) |
| DK (1) | DK2717897T3 (enExample) |
| ES (1) | ES2633343T3 (enExample) |
| IL (1) | IL229771B (enExample) |
| MX (1) | MX349146B (enExample) |
| PL (1) | PL2717897T3 (enExample) |
| WO (1) | WO2012174028A2 (enExample) |
| ZA (1) | ZA201309161B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2633343T3 (es) * | 2011-06-13 | 2017-09-20 | The Board Of Trustees Of The University Of Illionis | Composiciones de péptidos y métodos para tratar lesión pulmonar, asma, anafilaxis, angioedema, síndromes de permeabilidad vascular sistémica y congestión nasal |
| CN107427549B (zh) * | 2015-03-02 | 2022-01-11 | 伊利诺伊大学受托管理委员会 | 用于抑制血管生成的肽 |
| CN110128506B (zh) * | 2019-05-22 | 2021-03-30 | 中国药科大学 | 一种寡肽及其应用 |
| CN110664990B (zh) * | 2019-11-07 | 2021-03-16 | 江南大学 | 一种trpc1肽类分子在制备治疗病毒感染引起的炎症的药物中的应用 |
| TW202204375A (zh) * | 2020-04-15 | 2022-02-01 | 美商寇峇有限公司 | 治療冠狀病毒感染之方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US6093740A (en) * | 1997-04-30 | 2000-07-25 | Eli Lilly And Company | Therapeutic treatment for skin disorders |
| GB9718609D0 (en) * | 1997-09-02 | 1997-11-05 | Imp College Innovations Ltd | Fusion protein |
| US7368430B2 (en) * | 2003-11-06 | 2008-05-06 | Research Development Foundation | Selective inhibitors of nuclear factor-κB activation and uses thereof |
| KR101206843B1 (ko) * | 2003-12-03 | 2012-11-30 | 와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 | 튜불린 저해제 |
| AU2006292203A1 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| KR101399175B1 (ko) * | 2006-07-21 | 2014-06-19 | 푼다싸웅 지 앙빠루 아 뻬스끼자 두 에스따두 지 싸웅 파울루 - 에피아뻬에에씨뻬 | 항염증성 및 항알레르기성 시클릭 펩티드 |
| US7585865B2 (en) * | 2006-07-21 | 2009-09-08 | The Penn State Research Foundation | Protein kinase C zeta inhibition to treat vascular permeability |
| KR20200075044A (ko) * | 2008-01-22 | 2020-06-25 | 아라임 파마슈티칼즈, 인크. | 조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체 |
| FR2940032B1 (fr) | 2008-12-23 | 2013-08-09 | Seb Sa | Panier de cuisson d'aliments et systeme de cuisson correspondant |
| IT1392567B1 (it) * | 2008-12-24 | 2012-03-09 | Bioindustry Park Del Canavese S P A | Uso di un peptide derivato da er-alfa per il ripristino della sensibilita' a composti antiestrogenici in cellule di tumore mammario |
| US20100190691A1 (en) | 2009-01-27 | 2010-07-29 | Trojan Technologies, Ltd | Delivery of nucleic acids using cell-penetrating peptides |
| ES2633343T3 (es) * | 2011-06-13 | 2017-09-20 | The Board Of Trustees Of The University Of Illionis | Composiciones de péptidos y métodos para tratar lesión pulmonar, asma, anafilaxis, angioedema, síndromes de permeabilidad vascular sistémica y congestión nasal |
-
2012
- 2012-06-13 ES ES12800251.6T patent/ES2633343T3/es active Active
- 2012-06-13 BR BR112013032108-3A patent/BR112013032108B1/pt not_active IP Right Cessation
- 2012-06-13 CN CN201280029277.6A patent/CN103608026B/zh active Active
- 2012-06-13 MX MX2013014650A patent/MX349146B/es active IP Right Grant
- 2012-06-13 WO PCT/US2012/042118 patent/WO2012174028A2/en not_active Ceased
- 2012-06-13 PL PL12800251T patent/PL2717897T3/pl unknown
- 2012-06-13 DK DK12800251.6T patent/DK2717897T3/en active
- 2012-06-13 CA CA2838662A patent/CA2838662C/en active Active
- 2012-06-13 AU AU2012271781A patent/AU2012271781C1/en active Active
- 2012-06-13 CN CN201610552695.3A patent/CN106188232B/zh active Active
- 2012-06-13 EP EP12800251.6A patent/EP2717897B1/en active Active
- 2012-06-13 US US14/105,385 patent/US9248198B2/en active Active
- 2012-06-13 KR KR1020137033193A patent/KR102042015B1/ko not_active Expired - Fee Related
- 2012-06-13 JP JP2014515930A patent/JP6042425B2/ja not_active Expired - Fee Related
-
2013
- 2013-12-03 IL IL229771A patent/IL229771B/en active IP Right Grant
- 2013-12-05 ZA ZA2013/09161A patent/ZA201309161B/en unknown
-
2014
- 2014-03-31 US US14/230,642 patent/US8912139B2/en active Active
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