JP2014516924A - 粘度が低減された処方物 - Google Patents
粘度が低減された処方物 Download PDFInfo
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- JP2014516924A JP2014516924A JP2014504013A JP2014504013A JP2014516924A JP 2014516924 A JP2014516924 A JP 2014516924A JP 2014504013 A JP2014504013 A JP 2014504013A JP 2014504013 A JP2014504013 A JP 2014504013A JP 2014516924 A JP2014516924 A JP 2014516924A
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (3)
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| US201161473121P | 2011-04-07 | 2011-04-07 | |
| US61/473,121 | 2011-04-07 | ||
| PCT/US2012/032462 WO2012138958A1 (en) | 2011-04-07 | 2012-04-06 | Formulations with reduced viscosity |
Publications (2)
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| JP2014516924A true JP2014516924A (ja) | 2014-07-17 |
| JP2014516924A5 JP2014516924A5 (enExample) | 2016-01-28 |
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| US (1) | US20140023655A1 (enExample) |
| EP (2) | EP3058952A1 (enExample) |
| JP (1) | JP2014516924A (enExample) |
| KR (1) | KR20140018966A (enExample) |
| CN (1) | CN103596585A (enExample) |
| AU (2) | AU2012240050B2 (enExample) |
| BR (1) | BR112013025866A2 (enExample) |
| CA (1) | CA2832556A1 (enExample) |
| EA (1) | EA201391488A1 (enExample) |
| IL (1) | IL228591A0 (enExample) |
| SG (1) | SG193963A1 (enExample) |
| WO (1) | WO2012138958A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023533704A (ja) * | 2020-07-13 | 2023-08-04 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 高濃度タンパク質製剤用の粘度低減賦形剤及びそれらの組み合わせ |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO2523688T3 (enExample) * | 2010-01-15 | 2018-03-10 | ||
| EP3578203A1 (en) | 2011-10-28 | 2019-12-11 | Integritybio Inc. | Protein formulations containing amino acids |
| FR2994390B1 (fr) | 2012-08-10 | 2014-08-15 | Adocia | Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee |
| WO2014141149A1 (en) * | 2013-03-15 | 2014-09-18 | Glaxosmithkline Intellectual Property (No.2) Limited | Formulations with reduced viscosity |
| WO2014169153A1 (en) * | 2013-04-10 | 2014-10-16 | Echogen, Inc. | Peptide complexes and therapeutic uses |
| JP6179939B2 (ja) * | 2013-07-09 | 2017-08-16 | 国立大学法人 筑波大学 | 高濃度γグロブリン製剤の粘度低下方法 |
| IL312865B2 (en) | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-lowering agents |
| SG11201702614SA (en) | 2014-10-01 | 2017-04-27 | Eagle Biolog Inc | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
| US20180264081A1 (en) * | 2015-01-18 | 2018-09-20 | Gloriana Therapeutics Sarl | Therapeutic protein formulations |
| CN116327921A (zh) | 2015-08-24 | 2023-06-27 | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 生物医药组合物 |
| US11603407B2 (en) * | 2017-04-06 | 2023-03-14 | Regeneron Pharmaceuticals, Inc. | Stable antibody formulation |
| WO2018211517A1 (en) | 2017-05-16 | 2018-11-22 | Bhami's Research Laboratory, Pvt. Ltd. | High concentration protein formulations with reduced viscosity |
| CA3134401A1 (en) | 2019-03-29 | 2020-10-08 | Jiangsu Hengrui Medicine Co., Ltd. | Pharmaceutical composition containing antibody against il-5 and use thereof |
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- 2012-04-06 CN CN201280026486.5A patent/CN103596585A/zh active Pending
- 2012-04-06 BR BR112013025866A patent/BR112013025866A2/pt not_active IP Right Cessation
- 2012-04-06 KR KR1020137029163A patent/KR20140018966A/ko not_active Withdrawn
- 2012-04-06 EP EP16154327.7A patent/EP3058952A1/en not_active Withdrawn
- 2012-04-06 EP EP12768307.6A patent/EP2694100A4/en not_active Withdrawn
- 2012-04-06 SG SG2013072426A patent/SG193963A1/en unknown
- 2012-04-06 US US14/110,182 patent/US20140023655A1/en not_active Abandoned
- 2012-04-06 EA EA201391488A patent/EA201391488A1/ru unknown
- 2012-04-06 WO PCT/US2012/032462 patent/WO2012138958A1/en not_active Ceased
- 2012-04-06 CA CA2832556A patent/CA2832556A1/en not_active Abandoned
- 2012-04-06 AU AU2012240050A patent/AU2012240050B2/en not_active Ceased
-
2013
- 2013-09-29 IL IL228591A patent/IL228591A0/en unknown
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023533704A (ja) * | 2020-07-13 | 2023-08-04 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 高濃度タンパク質製剤用の粘度低減賦形剤及びそれらの組み合わせ |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3058952A1 (en) | 2016-08-24 |
| BR112013025866A2 (pt) | 2016-12-20 |
| SG193963A1 (en) | 2013-11-29 |
| EA201391488A1 (ru) | 2014-01-30 |
| CA2832556A1 (en) | 2012-10-11 |
| AU2016202355A1 (en) | 2016-05-05 |
| AU2012240050B2 (en) | 2016-01-21 |
| IL228591A0 (en) | 2013-12-31 |
| WO2012138958A1 (en) | 2012-10-11 |
| CN103596585A (zh) | 2014-02-19 |
| EP2694100A4 (en) | 2014-10-01 |
| EP2694100A1 (en) | 2014-02-12 |
| KR20140018966A (ko) | 2014-02-13 |
| US20140023655A1 (en) | 2014-01-23 |
| AU2012240050A1 (en) | 2013-10-17 |
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