JP2014512820A5 - - Google Patents
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- Publication number
- JP2014512820A5 JP2014512820A5 JP2014508162A JP2014508162A JP2014512820A5 JP 2014512820 A5 JP2014512820 A5 JP 2014512820A5 JP 2014508162 A JP2014508162 A JP 2014508162A JP 2014508162 A JP2014508162 A JP 2014508162A JP 2014512820 A5 JP2014512820 A5 JP 2014512820A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- substrate
- period
- seeded
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims 23
- 210000000130 stem cell Anatomy 0.000 claims 17
- 239000000758 substrate Substances 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 4
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims 3
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims 3
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 238000005138 cryopreservation Methods 0.000 claims 3
- 229940126864 fibroblast growth factor Drugs 0.000 claims 3
- 230000035899 viability Effects 0.000 claims 3
- 238000010438 heat treatment Methods 0.000 claims 2
- VRBFTYUMFJWSJY-UHFFFAOYSA-N 28804-46-8 Chemical compound ClC1CC(C=C2)=CC=C2C(Cl)CC2=CC=C1C=C2 VRBFTYUMFJWSJY-UHFFFAOYSA-N 0.000 claims 1
- 102100035140 Vitronectin Human genes 0.000 claims 1
- 108010031318 Vitronectin Proteins 0.000 claims 1
- 210000004504 adult stem cell Anatomy 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 230000008602 contraction Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 1
- 108010082117 matrigel Proteins 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 229920000052 poly(p-xylylene) Polymers 0.000 claims 1
- 108010056030 retronectin Proteins 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 238000010257 thawing Methods 0.000 claims 1
- 210000001578 tight junction Anatomy 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 239000002699 waste material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161481015P | 2011-04-29 | 2011-04-29 | |
| US61/481,015 | 2011-04-29 | ||
| PCT/US2012/035676 WO2012149484A2 (en) | 2011-04-29 | 2012-04-27 | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017036933A Division JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014512820A JP2014512820A (ja) | 2014-05-29 |
| JP2014512820A5 true JP2014512820A5 (enExample) | 2015-06-18 |
| JP6200883B2 JP6200883B2 (ja) | 2017-09-20 |
Family
ID=47073114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014508162A Active JP6200883B2 (ja) | 2011-04-29 | 2012-04-27 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
| JP2017036933A Pending JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017036933A Pending JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10470457B2 (enExample) |
| EP (1) | EP2702135B1 (enExample) |
| JP (2) | JP6200883B2 (enExample) |
| ES (1) | ES2722207T3 (enExample) |
| WO (1) | WO2012149484A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG188122A1 (en) | 2004-01-23 | 2013-03-28 | Advanced Cell Tech Inc | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| ES2764473T3 (es) | 2007-10-12 | 2020-06-03 | Astellas Inst For Regenerative Medicine | Métodos mejorados para producir células RPE y composiciones de células RPE |
| WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| EP4245370A3 (en) | 2010-07-12 | 2023-11-29 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| EP2702135B1 (en) * | 2011-04-29 | 2019-04-17 | University of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| CA2855941A1 (en) * | 2011-11-14 | 2013-05-23 | Advanced Cell Technology, Inc. | Pharmaceutical preparations of human rpe cells and uses thereof |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| US20150368713A1 (en) | 2013-02-01 | 2015-12-24 | THE UNITED STATES OF AMERICAN, as represented by the Secretary, Department of Health and Human Serv | METHOD FOR GENERATING RETINAL PIGMENT EPITHELIUM (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCs) |
| US9977012B2 (en) | 2014-10-24 | 2018-05-22 | Lifeline Scientific, Inc. | Select on of extracellular matrix components and or matricellular proteins for improved post-cryopreservation cell viability and retention |
| MX2017008737A (es) | 2014-12-30 | 2018-01-25 | Cell Cure Neurosciences Ltd | Poblaciones de celulas rpe y metodos para generar las mismas. |
| ES2970537T3 (es) | 2015-09-08 | 2024-05-29 | Us Health | Método para la diferenciación reproducible de células epiteliales del pigmento retiniano de calidad clínica |
| AU2016318774B2 (en) | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| US10815456B2 (en) | 2016-10-04 | 2020-10-27 | Transwell Biotech Co., Ltd. | Composition, kit and method for cryopreserving cells |
| CN109988750A (zh) * | 2017-12-29 | 2019-07-09 | 江苏艾尔康生物医药科技有限公司 | 一种视网膜色素上皮细胞的培养方法 |
| SG11202005795TA (en) * | 2017-12-29 | 2020-07-29 | Cell Cure Neurosciences Ltd | Retinal pigment epithelium cell compositions |
| WO2020037416A1 (en) * | 2018-08-22 | 2020-02-27 | The Governors Of The University Of Alberta | Cryopreservation of cell monolayers |
| US11825839B2 (en) * | 2018-09-07 | 2023-11-28 | University Of Southern California | Cryopreservation of cell-seeded substrates and related methods |
| KR20210095885A (ko) | 2018-11-19 | 2021-08-03 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 생분해성 조직 대체 임플란트 및 그의 용도 |
| AU2020268199B2 (en) | 2019-05-09 | 2025-08-21 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of hepatocytes |
| JPWO2021045122A1 (enExample) * | 2019-09-02 | 2021-03-11 | ||
| US20230212509A1 (en) | 2020-05-29 | 2023-07-06 | FUJIFILM Cellular Dynamics, Inc. | Bilayer of retinal pigmented epithelium and photoreceptors and use thereof |
| KR20240011831A (ko) | 2021-05-26 | 2024-01-26 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 만능 줄기 세포에서 유전자의 신속한 사일런싱을 방지하기 위한 방법 |
| US20240261474A1 (en) | 2021-05-28 | 2024-08-08 | The U.S.A., As Represented By The Secretary, Department Of Health And Human Services | Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells |
| US20240271089A1 (en) | 2021-05-28 | 2024-08-15 | The U.S.A., As Represented By The Secretary, Department Of Health And Human Services | Methods to generate macular, central and peripheral retinal pigment epithelial cells |
| WO2022256502A1 (en) * | 2021-06-04 | 2022-12-08 | The Secant Group Llc | Cryopreservation compositions and methods including glycerol ester components |
| CN118339279A (zh) | 2021-10-29 | 2024-07-12 | 富士胶片细胞动力公司 | 包含突变的多巴胺能神经元及其使用方法 |
| US20240003871A1 (en) | 2022-06-29 | 2024-01-04 | FUJIFILM Cellular Dynamics, Inc. | Ipsc-derived astrocytes and methods of use thereof |
| WO2024137677A1 (en) | 2022-12-19 | 2024-06-27 | FUJIFILM Holdings America Corporation | Extracellular vesicle-enriched secretome composition derived from induced pluripotent stem cell derived-microglia and methods of use thereof |
| WO2025245202A1 (en) | 2024-05-21 | 2025-11-27 | FUJIFILM Cellular Dynamics, Inc. | Particle counting and biomass measurements of aggregated cell compositions |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4163828A (en) | 1978-01-20 | 1979-08-07 | Union Carbide Corporation | Parylene stabilization |
| JP2003047464A (ja) * | 2001-08-02 | 2003-02-18 | Institute Of Tsukuba Liaison Co Ltd | 動物細胞の保存方法 |
| US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| WO2005052138A1 (en) * | 2003-11-19 | 2005-06-09 | Wisconsin Alumni Research Foundation | Cryopreservation of pluripotent stem cells |
| US7691626B2 (en) * | 2003-11-21 | 2010-04-06 | The Regents Of The University Of California | Self-contained cell culture apparatus and method of use |
| US20060063141A1 (en) | 2004-09-17 | 2006-03-23 | Mcgann Locksley E | Method of cryopreserving cells |
| WO2007058308A1 (ja) * | 2005-11-17 | 2007-05-24 | Nippon Zenyaku Kogyo Co., Ltd. | 細胞保存用水溶液 |
| JP2007306856A (ja) * | 2006-05-18 | 2007-11-29 | Japan Health Science Foundation | 細胞凍結保存方法 |
| US7923823B2 (en) | 2007-01-23 | 2011-04-12 | Infineon Technologies Ag | Semiconductor device with parylene coating |
| US20090123992A1 (en) * | 2007-11-12 | 2009-05-14 | Milton Chin | Shape-Shifting Vitrification Device |
| EP3338549A1 (en) * | 2007-11-20 | 2018-06-27 | Pioneer Surgical Orthobiologics, Inc. | Cryopreservation of cells using cross-linked bioactive hydrogel matrix particles |
| EP4245370A3 (en) * | 2010-07-12 | 2023-11-29 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| EP2702135B1 (en) * | 2011-04-29 | 2019-04-17 | University of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| WO2012149315A1 (en) | 2011-04-29 | 2012-11-01 | Prucell David Scott | Glove dispensing apparatus and glove cartridge for use therewith and glove dispensing method |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| CA2792081C (en) | 2011-10-11 | 2020-10-27 | Bond University Ltd | Layered compositions comprising 3d nanofibre webbing for tissue repair |
| US20150368713A1 (en) | 2013-02-01 | 2015-12-24 | THE UNITED STATES OF AMERICAN, as represented by the Secretary, Department of Health and Human Serv | METHOD FOR GENERATING RETINAL PIGMENT EPITHELIUM (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCs) |
| JP6176336B2 (ja) | 2013-12-13 | 2017-08-09 | パナソニックＩｐマネジメント株式会社 | 便座装置、および便器装置 |
| AU2016318774B2 (en) | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
-
2012
- 2012-04-27 EP EP12776772.1A patent/EP2702135B1/en active Active
- 2012-04-27 ES ES12776772T patent/ES2722207T3/es active Active
- 2012-04-27 WO PCT/US2012/035676 patent/WO2012149484A2/en not_active Ceased
- 2012-04-27 JP JP2014508162A patent/JP6200883B2/ja active Active
-
2017
- 2017-01-27 US US15/418,099 patent/US10470457B2/en active Active
- 2017-02-28 JP JP2017036933A patent/JP2017184724A/ja active Pending
-
2019
- 2019-10-21 US US16/658,457 patent/US11533908B2/en active Active
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