JP2014510075A5 - - Google Patents

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Publication number
JP2014510075A5
JP2014510075A5 JP2013557068A JP2013557068A JP2014510075A5 JP 2014510075 A5 JP2014510075 A5 JP 2014510075A5 JP 2013557068 A JP2013557068 A JP 2013557068A JP 2013557068 A JP2013557068 A JP 2013557068A JP 2014510075 A5 JP2014510075 A5 JP 2014510075A5
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JP
Japan
Prior art keywords
patient
antibody
fluorescently labeled
cancer
tumor model
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Application number
JP2013557068A
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English (en)
Japanese (ja)
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JP2014510075A (ja
JP6100704B2 (ja
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Priority claimed from PCT/EP2012/053786 external-priority patent/WO2012119999A1/en
Publication of JP2014510075A publication Critical patent/JP2014510075A/ja
Publication of JP2014510075A5 publication Critical patent/JP2014510075A5/ja
Application granted granted Critical
Publication of JP6100704B2 publication Critical patent/JP6100704B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013557068A 2011-03-07 2012-03-06 治療用抗体についてのインビボ試験の手段および方法 Expired - Fee Related JP6100704B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11001857.9 2011-03-07
EP11001857 2011-03-07
PCT/EP2012/053786 WO2012119999A1 (en) 2011-03-07 2012-03-06 Means and methods for in vivo testing of therapeutic antibodies

Publications (3)

Publication Number Publication Date
JP2014510075A JP2014510075A (ja) 2014-04-24
JP2014510075A5 true JP2014510075A5 (OSRAM) 2015-04-23
JP6100704B2 JP6100704B2 (ja) 2017-03-22

Family

ID=44303255

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013557068A Expired - Fee Related JP6100704B2 (ja) 2011-03-07 2012-03-06 治療用抗体についてのインビボ試験の手段および方法

Country Status (4)

Country Link
US (1) US20140099264A1 (OSRAM)
EP (1) EP2683290B1 (OSRAM)
JP (1) JP6100704B2 (OSRAM)
WO (1) WO2012119999A1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6404687B2 (ja) * 2014-11-21 2018-10-10 倉敷紡績株式会社 蛍光イメージング装置及び蛍光イメージング方法
CA2992370A1 (en) * 2015-04-06 2016-10-13 University Of Miami Imaging device and method for detection of disease
WO2017141987A1 (ja) * 2016-02-19 2017-08-24 コニカミノルタ株式会社 実験動物検体を定量評価することを特徴とする、非臨床試験方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
DE69233528T2 (de) 1991-11-25 2006-03-16 Enzon, Inc. Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
PT1621554E (pt) 1992-08-21 2009-07-13 Univ Bruxelles Imunoglobtainas desprovidas de cadeias leves
KR100397020B1 (ko) 1995-01-30 2004-04-29 다이이치 가가쿠 야쿠힝 가부시키가이샤 진단용마커
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
JP2000515002A (ja) 1996-06-27 2000-11-14 フラームス・インテルウニフェルジテール・インスティテュート・フォール・ビオテヒノロジー・ヴェーゼットウェー 標的分子の活性部位またはクレフトと特異的に相互作用する認識分子
DE19717904A1 (de) 1997-04-23 1998-10-29 Diagnostikforschung Inst Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie
US6592847B1 (en) 1998-05-14 2003-07-15 The General Hospital Corporation Intramolecularly-quenched near infrared flourescent probes
US6083486A (en) 1998-05-14 2000-07-04 The General Hospital Corporation Intramolecularly-quenched near infrared fluorescent probes
US6615063B1 (en) 2000-11-27 2003-09-02 The General Hospital Corporation Fluorescence-mediated molecular tomography
EP1379284A4 (en) 2001-01-05 2007-07-25 Gen Hospital ACTIVE IMAGING PROBES
US20030044353A1 (en) 2001-01-05 2003-03-06 Ralph Weissleder Activatable imaging probes
US20060147378A1 (en) 2002-09-24 2006-07-06 Ching-Hsuan Tung Azulene dimer-quenched, near-infrared fluorescent probes
EP2284192A3 (en) 2002-11-08 2011-07-20 Ablynx N.V. Camelidae antibodies for sublingual administration
EP1558647B1 (en) 2002-11-08 2015-06-10 Ablynx N.V. Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
EP1679082A1 (en) 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases
WO2006107864A1 (en) 2005-04-04 2006-10-12 Blueshift Biotechnologies, Inc. Screening using polarization anisotropy in fret emissions
WO2007067978A1 (en) 2005-12-09 2007-06-14 Invitrogen Corporation Optical in vivo imaging contrast agents and methods of use
SG178789A1 (en) 2007-02-16 2012-03-29 Merrimack Pharmaceuticals Inc Antibodies against erbb3 and uses thereof
JP5426026B2 (ja) 2009-07-28 2014-02-26 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 非侵襲性インビボ光学イメージング方法

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