JP2014508300A5 - - Google Patents

Download PDF

Info

Publication number
JP2014508300A5
JP2014508300A5 JP2013556907A JP2013556907A JP2014508300A5 JP 2014508300 A5 JP2014508300 A5 JP 2014508300A5 JP 2013556907 A JP2013556907 A JP 2013556907A JP 2013556907 A JP2013556907 A JP 2013556907A JP 2014508300 A5 JP2014508300 A5 JP 2014508300A5
Authority
JP
Japan
Prior art keywords
nanopipette
nanopore
binding molecule
binding
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013556907A
Other languages
English (en)
Japanese (ja)
Other versions
JP6046058B2 (ja
JP2014508300A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/027531 external-priority patent/WO2012122029A2/en
Publication of JP2014508300A publication Critical patent/JP2014508300A/ja
Publication of JP2014508300A5 publication Critical patent/JP2014508300A5/ja
Application granted granted Critical
Publication of JP6046058B2 publication Critical patent/JP6046058B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013556907A 2011-03-04 2012-03-02 可逆的なイオン及び分子検出又は移動用ナノポアデバイス Expired - Fee Related JP6046058B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161449379P 2011-03-04 2011-03-04
US61/449,379 2011-03-04
PCT/US2012/027531 WO2012122029A2 (en) 2011-03-04 2012-03-02 Nanopore device for reversible ion and molecule sensing or migration

Publications (3)

Publication Number Publication Date
JP2014508300A JP2014508300A (ja) 2014-04-03
JP2014508300A5 true JP2014508300A5 (https=) 2016-06-30
JP6046058B2 JP6046058B2 (ja) 2016-12-14

Family

ID=46752618

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013556907A Expired - Fee Related JP6046058B2 (ja) 2011-03-04 2012-03-02 可逆的なイオン及び分子検出又は移動用ナノポアデバイス

Country Status (6)

Country Link
US (4) US8980073B2 (https=)
EP (1) EP2681542B1 (https=)
JP (1) JP6046058B2 (https=)
KR (1) KR101923241B1 (https=)
CN (2) CN103502804B (https=)
WO (1) WO2012122029A2 (https=)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009134354A1 (en) 2008-04-30 2009-11-05 Flanigan Theodore P System and method for pre-treatment of rubber-modified asphalt cement, and emulsions thereof
US8262879B2 (en) 2008-09-03 2012-09-11 Nabsys, Inc. Devices and methods for determining the length of biopolymers and distances between probes bound thereto
US9650668B2 (en) 2008-09-03 2017-05-16 Nabsys 2.0 Llc Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels
EP2346940A4 (en) 2008-09-24 2013-04-24 Wright Advanced Asphalt Systems SYSTEM AND METHOD FOR THE PRODUCTION OF RUBBER-MODIFIED ASPHALT CEMENT HIGH-PERFORMANCE
WO2012067911A1 (en) 2010-11-16 2012-05-24 Nabsys, Inc. Methods for sequencing a biomolecule by detecting relative positions of hybridized probes
US11274341B2 (en) 2011-02-11 2022-03-15 NABsys, 2.0 LLC Assay methods using DNA binding proteins
CN103502804B (zh) 2011-03-04 2015-07-22 加利福尼亚大学董事会 用于可逆的离子和分子感测或迁移的纳米孔装置
EP2697394A4 (en) 2011-04-12 2015-01-14 Electronic Biosciences Inc CHEMICALLY MODIFIED NANOPORA DEVICES AT A SPECIFIC SITE
US20150204873A1 (en) * 2012-06-18 2015-07-23 Electonic Biosciences, Inc. Cell-free assay device and methods of use
US9910008B2 (en) 2012-07-06 2018-03-06 Robert Bosch Gmbh Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions
US9810688B2 (en) 2013-03-15 2017-11-07 Robert Bosch Gmbh Smart glass slide for microarrays
US9874538B2 (en) 2012-07-06 2018-01-23 Robert Bosch Gmbh Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions
US9021864B2 (en) * 2012-08-21 2015-05-05 International Business Machines Corporation Sensing biomolecules using scanning probe with twin-nanopore to detect a change in the magnitude of the current through the second nanopore
RU2510017C1 (ru) * 2012-10-25 2014-03-20 Федеральное государственное бюджетное учреждение высшего профессионального образования "Национальный исследовательский Томский политехнический университет" Способ определения аскорбата кальция в биологически активных добавках методом вольтамперометрии
US9914966B1 (en) * 2012-12-20 2018-03-13 Nabsys 2.0 Llc Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation
US9791453B2 (en) 2012-12-26 2017-10-17 International Business Machines Corporation Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels
WO2014113557A1 (en) 2013-01-18 2014-07-24 Nabsys, Inc. Enhanced probe binding
JP6453300B2 (ja) 2013-03-14 2019-01-16 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 細胞内分析のためのナノピペット装置および方法
US9753009B2 (en) 2013-04-17 2017-09-05 Revalesio Corporation Methods and apparatus for trapping and size resolution of nanoparticles and nanobubbles
CA2909297A1 (en) * 2013-04-17 2014-10-23 Revalesio Corporation Controlling nanobubble and nanoparticle dynamics in conical nanopores
WO2014189960A1 (en) * 2013-05-22 2014-11-27 University Of Notre Dame Du Lac Method and apparatus for a nanopipette biosensor
US20150037787A1 (en) * 2013-07-31 2015-02-05 International Business Machines Corporation Polynucleotide configuration for reliable electrical and optical sensing
EP3039155B1 (en) * 2013-08-26 2019-10-09 Ontera Inc. Molecule detection using boronic acid substituted probes
US10024851B2 (en) 2013-10-15 2018-07-17 International Business Machines Corporation Use of disulfide bonds to form a reversible and reusable coating for nanofluidic devices
US9303310B2 (en) 2013-10-15 2016-04-05 International Business Machines Corporation Nanofluidic sensor comprising spatially separated functional sensing components
US9255321B2 (en) 2013-10-15 2016-02-09 Globalfoundries Inc. Directed surface functionalization on selected surface areas of topographical features with nanometer resolution
US10197498B2 (en) * 2013-10-21 2019-02-05 Northeastern University Compositions and methods for measurement of analytes
EP3105572B1 (en) 2014-02-13 2019-04-10 Robert Bosch GmbH Capacitive bubble detection
US10352898B2 (en) 2014-02-26 2019-07-16 University Of Central Florida Research Foundaing, Inc. Capillary ionic transistor
US10335781B2 (en) 2014-05-16 2019-07-02 Konkuk University Industrial Cooperation Corp Nanopipette provided with membrane containing saturated ion-sensitive material, method for preparing same, and ion measuring apparatus comprising same
DE102014007519A1 (de) * 2014-05-22 2015-11-26 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zur Bestimmung des zentralen systolischen Blutdrucks
US9921181B2 (en) 2014-06-26 2018-03-20 International Business Machines Corporation Detection of translocation events using graphene-based nanopore assemblies
JP6401588B2 (ja) * 2014-11-28 2018-10-10 株式会社アドバンテスト 電流測定装置および塩基配列解析装置、測定用チップ
EP3262404A4 (en) * 2015-02-25 2018-12-12 The Regents of the University of California Single-cell intracellular nano-ph probes
GB201508003D0 (en) * 2015-05-11 2015-06-24 Oxford Nanopore Tech Ltd Apparatus and methods for measuring an electrical current
GB201510322D0 (en) * 2015-06-12 2015-07-29 Imp Innovations Ltd Apparatus and method
US10011549B2 (en) 2015-07-06 2018-07-03 Robert Bosch Gmbh Electrochemically active agents for pH modulation in biological buffers
US11867660B2 (en) 2015-07-06 2024-01-09 Robert Bosch Gmbh Electronic control of the pH of a solution close to an electrode surface
US10379080B2 (en) 2015-07-06 2019-08-13 Robert Bosch Gmbh Electronic control of the pH of a solution close to an electrode surfaces
JP6905543B2 (ja) 2016-06-15 2021-07-21 イーストマン ケミカル カンパニー 物理蒸着したバイオセンサー部品
EP3512957B1 (en) 2016-09-16 2022-03-09 Eastman Chemical Company Biosensor electrodes prepared by physical vapor deposition
JP7111698B2 (ja) 2016-09-16 2022-08-02 イーストマン ケミカル カンパニー 物理蒸着によって製造されるバイオセンサー電極
CN107884329B (zh) * 2016-09-29 2020-03-10 中国科学院化学研究所 检测单颗粒的方法和装置
US11559817B2 (en) 2017-05-17 2023-01-24 University Of Cincinnati Using electrokinetic forces to manipulate suspended particles
SG11201910864UA (en) * 2017-06-20 2020-01-30 Illumina Inc Nanopore sequencers
WO2018236572A1 (en) 2017-06-22 2018-12-27 Eastman Chemical Company PHYSICAL DEPOSITION ELECTRODE IN VAPOR PHASE FOR ELECTROCHEMICAL SENSORS
CN107356580B (zh) * 2017-06-27 2020-04-03 南京大学 一种基于单分散纳米片层的纳米单孔及其制备方法和应用
CN107505379B (zh) * 2017-08-16 2019-06-11 中国科学院植物研究所 一种毛细管电泳分离小麦醇溶蛋白的方法
US11325987B2 (en) 2017-10-11 2022-05-10 Arizona Board Of Regents On Behalf Of Arizona State University Solid state nanopores aided by machine learning for identification and quantification of heparins and glycosaminoglycans
CN107991374B (zh) * 2017-11-30 2019-12-10 江苏省农业科学院 基于CS-Zn NPs传感器检测肉品中肌动蛋白的方法
US12196750B2 (en) * 2018-02-12 2025-01-14 The Regents Of The University Of California Methods for simultaneous detection of analytes and apparatuses for practicing same
CN108919844A (zh) * 2018-05-15 2018-11-30 电子科技大学 一种化学反应速率实时溶液浓度自动控制系统
KR102086414B1 (ko) * 2018-05-31 2020-03-09 건국대학교 산학협력단 포화된 이온감지물질을 포함하는 막을 구비하는 나노피펫의 제조방법
KR102086107B1 (ko) * 2018-05-31 2020-03-06 건국대학교 산학협력단 포화된 이온감지물질을 포함하는 막을 구비하는 나노피펫
WO2020032294A1 (ko) * 2018-08-09 2020-02-13 (주)비비비 자성 나노입자를 이용한 바이오센서, 이를 이용하는 검출 장치 및 검출 방법
US11181501B2 (en) 2018-09-11 2021-11-23 City University Of Hong Kong Method and an apparatus for determining a presence or an amount of a polyamine or its derivative in a sample
US12384856B2 (en) 2018-10-30 2025-08-12 The Research Foundation For The State University Of New York Compositions and methods for removal of negatively charged impurities using metal-cellulose fiber composite
CN113508285B (zh) * 2019-03-12 2024-12-06 国立大学法人东北大学 内毒素检测装置、及内毒素的检测方法
US20200326325A1 (en) 2019-04-12 2020-10-15 Lisa Diamond Nanosensor chip with compound nanopores
CN110132921B (zh) * 2019-05-16 2021-09-14 中国科学院重庆绿色智能技术研究院 一种基于针尖纳米孔单分子检测技术的实时监控酶切反应的方法
CN110132947B (zh) * 2019-06-14 2021-09-28 福州大学 一种锥形微米孔表面电荷密度调控电致化学发光信号的方法
CN110606463A (zh) * 2019-07-24 2019-12-24 西北工业大学 制备基于固态纳米孔的对温度和pH双重响应的纳米流体二极管的方法
EP4062164A4 (en) * 2019-12-26 2023-01-25 Ege Universitesi CARBOHYDRATE POLYMER SENSOR AND METHOD FOR DEVELOPING SAME SENSOR
WO2021240440A1 (en) * 2020-05-27 2021-12-02 Gisens Biotech Sa Sensors and systems based on two-dimensional nanosheet field-effect transistors, methods of preparation and devices for their operation
CN112851821B (zh) * 2021-01-12 2022-07-05 山东省科学院生物研究所 一种融合酶及所述融合酶在纸基生物传感器中的应用
CN112746289B (zh) * 2021-01-21 2021-11-09 合肥工业大学 一种烷基硼酸酯类化合物的合成方法
US11994484B2 (en) * 2021-03-25 2024-05-28 The Regents Of The University Of California Apparatus and method for single cell discrimination
US20240418701A1 (en) * 2021-10-09 2024-12-19 Nanjing University Single molecule identification with a reactive hetero-nanopore
CN114166911B (zh) * 2021-11-17 2023-12-12 大连民族大学 基于微流控的海洋金属离子检测系统及电化学传感器的涂料的制备方法
CN114965646B (zh) * 2022-05-20 2023-08-29 复旦大学 基于超组装策略得到的mc/aao/ms纳米通道膜在离子存储与释放的应用
CN116223589B (zh) * 2023-02-22 2025-11-21 海南大学 基于盐差转换的盐溶液pH检测装置及方法
CN117554315A (zh) * 2023-09-28 2024-02-13 宁波慈溪生物医学工程研究所 一种排除干扰物质影响的葡萄糖精准检测方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4384075A (en) * 1981-12-11 1983-05-17 Owens-Corning Fiberglas Corporation Cationic alkenyl azabenzene and rubber modified asphalts
ZA889546B (en) * 1987-12-24 1990-08-29 Igen Inc Chemical sensors employing catalytic antibodies
US5447617A (en) * 1994-01-25 1995-09-05 Beckman Instruments, Inc. Coated capillary columns and electrophoretic separation methods for their use
KR20030055346A (ko) * 2000-12-11 2003-07-02 프레지던트 앤드 펠로우즈 오브 하버드 칼리지 나노센서
US7297486B2 (en) * 2001-06-14 2007-11-20 Ionscope Ltd. Production of molecular arrays
JP2005535283A (ja) * 2001-11-13 2005-11-24 ルビコン ゲノミクス インコーポレイテッド ランダムフラグメント化により生成されたｄｎａ分子を用いたｄｎａ増幅および配列決定
DE10244914A1 (de) 2002-09-25 2004-05-06 Gesellschaft für Schwerionenforschung mbH Nanovorrichtung für einen geladenen Teilchenfluß und Verfahren zu deren Herstellung
US20050260119A1 (en) * 2003-09-09 2005-11-24 Sunkara Mahendra K Carbon nanopipettes methods of making and applications
US7955738B2 (en) * 2004-03-05 2011-06-07 Honeywell International, Inc. Polymer ionic electrolytes
JP4558382B2 (ja) * 2004-06-04 2010-10-06 ジーエルサイエンス株式会社 アフィニティクロマトグラフィ用デバイス及びその製法
WO2006000064A2 (en) * 2004-06-28 2006-01-05 Interuniversitair Microelektronica Centrum Vzw Device for controlling the flow of charged carriers through a nanopore in a mebmrane and method for the fabrication of such a device
US7785785B2 (en) * 2004-11-12 2010-08-31 The Board Of Trustees Of The Leland Stanford Junior University Charge perturbation detection system for DNA and other molecules
US8083926B2 (en) * 2006-04-19 2011-12-27 Chen Ellen T Nanopore structured electrochemical biosensors
US7849581B2 (en) * 2006-05-05 2010-12-14 University Of Utah Research Foundation Nanopore electrode, nanopore membrane, methods of preparation and surface modification, and use thereof
US7777505B2 (en) * 2006-05-05 2010-08-17 University Of Utah Research Foundation Nanopore platforms for ion channel recordings and single molecule detection and analysis
EP2105735B1 (en) * 2006-12-26 2014-11-26 Sekisui Chemical Co., Ltd. STABLE HEMOGLOBIN A1c MEASUREMENT METHOD AND ELECTROPHORESIS APPARATUS
WO2009069007A2 (en) * 2007-11-30 2009-06-04 Glycominds, Ltd. Composition and method for prediction of complicated disease course and surgeries in crohn's disease
US8940142B2 (en) * 2008-05-05 2015-01-27 The Regents Of The University Of California Functionalized nanopipette biosensor
CN103502804B (zh) * 2011-03-04 2015-07-22 加利福尼亚大学董事会 用于可逆的离子和分子感测或迁移的纳米孔装置

Similar Documents

Publication Publication Date Title
JP2014508300A5 (https=)
Alizadeh et al. Application of an Hg2+ selective imprinted polymer as a new modifying agent for the preparation of a novel highly selective and sensitive electrochemical sensor for the determination of ultratrace mercury ions
Economou et al. Mercury film electrodes: developments, trends and potentialities for electroanalysis
Hatamluyi et al. Au/Pd@ rGO nanocomposite decorated with poly (L-Cysteine) as a probe for simultaneous sensitive electrochemical determination of anticancer drugs, Ifosfamide and Etoposide
Radi et al. Reusable impedimetric aptasensor
Serrano et al. Antimony-based electrodes for analytical determinations
Su et al. Determination of endotoxin through an aptamer-based impedance biosensor
Yarkaeva et al. Voltammetric sensor system based on Cu (II) and Zn (II) amino acid complexes for recognition and determination of atenolol enantiomers
Cui et al. Electrochemical detection of Cu2+ through Ag nanoparticle assembly regulated by copper-catalyzed oxidation of cysteamine
US12292406B2 (en) Device for detecting analytes in a sample, and methods of use thereof
Hong et al. A dopamine electrochemical sensor based on molecularly imprinted poly (acrylamidophenylboronic acid) film
Daizy et al. ZnO hollow spheres arrayed molecularly-printed-polymer based selective electrochemical sensor for methyl-parathion pesticide detection
Li et al. Gold nanoparticles modified electrode via a mercapto-diazoaminobenzene monolayer and its development in DNA electrochemical biosensor
CN104181217A (zh) 基于磁性表面分子印迹聚合物的阻抗型电化学传感器构建及应用
CN104237344A (zh) 用于卡那霉素检测的电化学适体电极及其制备方法
Nigović et al. Square-wave voltammetric determination of pantoprazole using ex situ plated antimony-film electrode
Zhang et al. Ultrasensitive electrochemical biosensing for DNA using quantum dots combined with restriction endonuclease
CN105866205A (zh) 基于金纳米粒子-巯基化石墨烯修饰电极的电化学dna生物传感器的构建及应用
Das et al. Recent advancements of metal–organic frameworks in sensing platforms: relevance in the welfare of the environment and the medical sciences with regard to cancer and SARS-CoV-2
CN104280435A (zh) 一种石墨烯修饰的玻碳电极及制备方法和应用
FR3043779A1 (fr) Systeme de detection electrochimique de molecules d'interet.
Wang et al. Microswimmer-based electrochemical platform with active capturer/signal amplifier/funnel-type device for whole blood detection
CN107727717A (zh) 多氯联苯光电化学适配体传感器的制备方法及应用
Bala et al. Peptide nucleic acid as a selective recognition element for electrochemical determination of Hg2+
CN105588866B (zh) 一种识别双香豆素分子印迹电化学传感器的制备