JP2014507123A5 - - Google Patents

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Publication number
JP2014507123A5
JP2014507123A5 JP2013544771A JP2013544771A JP2014507123A5 JP 2014507123 A5 JP2014507123 A5 JP 2014507123A5 JP 2013544771 A JP2013544771 A JP 2013544771A JP 2013544771 A JP2013544771 A JP 2013544771A JP 2014507123 A5 JP2014507123 A5 JP 2014507123A5
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JP
Japan
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mir
hsa
mirna
kit
level
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JP2013544771A
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English (en)
Japanese (ja)
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JP2014507123A (ja
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Priority claimed from PCT/US2011/065120 external-priority patent/WO2012083004A2/en
Publication of JP2014507123A publication Critical patent/JP2014507123A/ja
Publication of JP2014507123A5 publication Critical patent/JP2014507123A5/ja
Pending legal-status Critical Current

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JP2013544771A 2010-12-15 2011-12-15 心臓病状に対する薬効のサロゲートマーカーとしての血中ｍｉＲＮＡ Pending JP2014507123A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US42345610P 2010-12-15 2010-12-15
US61/423,456 2010-12-15
US201161495220P 2011-06-09 2011-06-09
US61/495,220 2011-06-09
US201161538585P 2011-09-23 2011-09-23
US61/538,585 2011-09-23
PCT/US2011/065120 WO2012083004A2 (en) 2010-12-15 2011-12-15 Blood-borne mirnas as surrogate markers of drug efficacy for cardiac conditions

Publications (2)

Publication Number Publication Date
JP2014507123A JP2014507123A (ja) 2014-03-27
JP2014507123A5 true JP2014507123A5 (https=) 2015-02-05

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ID=45444747

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Application Number Title Priority Date Filing Date
JP2013544771A Pending JP2014507123A (ja) 2010-12-15 2011-12-15 心臓病状に対する薬効のサロゲートマーカーとしての血中ｍｉＲＮＡ

Country Status (7)

Country Link
US (1) US20140024700A1 (https=)
EP (1) EP2652146A2 (https=)
JP (1) JP2014507123A (https=)
CN (1) CN103370424A (https=)
AU (1) AU2011343719A1 (https=)
CA (1) CA2818174A1 (https=)
WO (1) WO2012083004A2 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
WO2014083081A1 (en) * 2012-11-27 2014-06-05 Centre de Recherche Public de la Santé Compositions and methods for evaluating heart failure
CN103290116B (zh) * 2013-05-16 2016-09-07 南京市妇幼保健院 一种与胎儿先天性心脏病相关的母体血清/血浆miRNA标志物及其应用
US20160251720A1 (en) * 2013-11-01 2016-09-01 The Trustees Of Columbia University In The City New York MicroRNA PROFILES IN HEART FAILURE: METHODS AND SYSTEMS FOR DETECTION AND USE
CN103667459A (zh) * 2013-11-26 2014-03-26 上海中医药大学附属岳阳中西医结合医院 微小核苷酸在高血压诊断和制备降血压药物中的应用
CN104740648B (zh) * 2013-12-27 2020-02-14 江苏命码生物科技有限公司 miRNA-214抑制剂在抑制调节性T细胞中的应用
CN104031987B (zh) * 2014-05-12 2016-08-31 贵州省人民医院 miRNA在心肌纤维化疾病治疗中的应用
US10131952B2 (en) 2014-05-14 2018-11-20 Ohio State Innovation Foundation MIRNA biomarkers for monitoring bone marrow reconstitution
EP3034623A1 (en) * 2014-12-18 2016-06-22 Centro de Investigación Biomédica en Red (CIBER) Method for predicting response to continuous positive air pressure treatment
WO2016177776A1 (en) * 2015-05-04 2016-11-10 Academisch Medisch Centrum Biomarkers for the detection of aspirin insensitivity
WO2016182511A1 (en) * 2015-05-08 2016-11-17 Agency For Science, Technology And Research Method for diagnosis and prognosis of chronic heart failure
CN105999302A (zh) * 2016-06-13 2016-10-12 上海市东方医院 一种miRNA-21a抑制剂及在制备延缓心肌梗死的药物中的用途
CN107557464B (zh) * 2016-07-02 2021-06-04 上海市公共卫生临床中心 用于干扰素治疗慢性乙型肝炎早期病毒学反应的预测模型及检测试剂盒
CN106399473B (zh) * 2016-08-23 2019-12-06 南京大学 检测和评价力量训练效果的miRNA标志物或其组合及其应用
EP4035659A1 (en) 2016-11-29 2022-08-03 PureTech LYT, Inc. Exosomes for delivery of therapeutic agents
CN106729757A (zh) * 2017-03-08 2017-05-31 复旦大学附属中山医院 miR‑378抑制心肌肥厚和心肌纤维化并诊断心力衰竭的用途
CN107858419A (zh) * 2017-11-10 2018-03-30 青岛大学 miRNA的应用、应用其的产品及检测方法
CN107881173A (zh) * 2017-11-16 2018-04-06 上海市东方医院 一种miRNA‑21小分子及其用途
CN108004316A (zh) * 2018-01-09 2018-05-08 青岛大学 用于预测急性心肌梗死风险的试剂盒
CN108866177B (zh) * 2018-05-31 2021-05-28 李继承 hsa-miRNA-423-5p和hsa-miRNA-423-5p抑制剂的用途
CN110055322A (zh) * 2019-05-12 2019-07-26 青岛大学 用于急性心肌梗死诊断的循环miRNA标志物及其应用
US20230288431A1 (en) * 2020-06-08 2023-09-14 National University Corporation Tokai National Higher Education And Research System Use of micro-rna to improve and treat chronic phase cardiac function
CN112410414B (zh) * 2020-10-09 2022-07-08 嘉兴市妇幼保健院 孕妇血清外泌体miRNA标志物在制备胎儿先心病早期诊断产品中的应用及试剂盒
CN113943792A (zh) * 2021-11-02 2022-01-18 石河子大学 检测miRNA表达量的试剂在制备诊断或预后哈萨克族高血压的试剂或试剂盒中的应用
CN116726038B (zh) * 2022-03-04 2026-04-17 南京大学 来源于棕榈炭的microRNA或其组合在制备止血药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090306181A1 (en) * 2006-09-29 2009-12-10 Children's Medical Center Corporation Compositions and methods for evaluating and treating heart failure
US20090105174A1 (en) * 2007-04-20 2009-04-23 Amgen Inc. Nucleic acids hybridizable to micro rna and precursors thereof
CN101802227B (zh) * 2007-07-18 2014-12-10 科罗拉多大学董事会法人团体 非衰竭与衰竭的人心脏中微小rna的差异表达
WO2009157204A1 (ja) * 2008-06-27 2009-12-30 学校法人 慶應義塾 バイオマーカーとしてのマイクロｒｎａを用いた婦人科がんの診断・治療選択
CN102356162A (zh) * 2009-02-04 2012-02-15 得克萨斯系统大学董事会 Mir-208和mir-499在治疗心脏病症中的双重靶向
WO2010130351A1 (en) * 2009-05-15 2010-11-18 Bayer Schering Pharma Ag Micrornas as biomarkers and therapeutic targets for heart failure
CN101643791A (zh) * 2009-09-04 2010-02-10 哈尔滨医科大学 microRNA-328及其反义核苷酸在诊断、防治心脏疾病中的用途

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