JP2014506523A - 非合焦超音波による超音波振動法 - Google Patents
非合焦超音波による超音波振動法 Download PDFInfo
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Abstract
【選択図】図2A
Description
Claims (22)
- 対象物の機械的特性を超音波で測定する方法であって、
イ)非合焦超音波エネルギを対象物に印加して対象物物に伝搬するせん断波を生成する工程と、
ロ)イ)の工程で生成した前記せん断波の存在する前記対象物の中の少なくとも1箇所を測定する検出器を用いて測定情報を取得する工程と、
ハ)ロ)の工程で取得した前記測定情報を用いて前記対象物の機械的特性を算出する工程と、
を含むことを特徴とする方法。 - 前記検出器が超音波装置とされ、前記対象物の中の少なくとも1箇所に超音波エネルギを印加することによって、前記ロ)の工程において前記測定情報を取得することを特徴とする請求項1に記載の方法。
- 前記ロ)の工程で印加する前記超音波エネルギが合焦超音波エネルギおよび非合焦超音波エネルギの少なくとも1つであることを特徴とする請求項2に記載の方法。
- 前記検出器が、光学検出器、磁気共鳴画像装置、および電磁波検出器の少なくとも1つとされ、電磁エネルギを前記対象物の少なくとも1箇所に印加することによって、前記ロ)の工程において前記測定情報を取得することを特徴とする請求項1に記載の方法。
- 前記イ)の工程において前記対象物に印加する非合焦超音波に、くし型パターンの超音波トランスデューサから外側へ延びる複数の非合焦超音波ビームが含まれていることを特徴とする請求項1に記載の方法。
- 前記複数の非合焦超音波ビームが、前記超音波トランスデューサの表面に亘って均等に離れていることを特徴とする請求項5に記載の方法。
- 前記ハ)の工程が、前記ロ)の工程で取得した測定情報に配向フィルタを適用することによって、異なる方向に伝搬するせん断波間の干渉が実質的に軽減されることを含むことを特徴とする請求項1〜5の何れか1つに記載の方法。
- 前記ハ)の工程が、
前記ロ)の工程で取得した測定情報から、第1の方向に伝搬するせん断波の測定に対応する第1の測定情報サブセットを形成する工程と、
前記ロ)の工程で取得した測定情報から、第2の方向に伝搬するせん断波の測定に対応する第2の測定情報サブセットを形成する工程と、
測定情報の、第1の測定情報サブセットおよび第2の測定情報サブセットを選択的に結合する工程と、
を含むことを特徴とする請求項5の記載の方法。 - 前記第1の方向が左から右への方向とされ、前記第2の方向が右から左への方向とされる請求項8に記載の方法。
- 前記イ)の工程には、複数の超音波トランスデューサ構成要素を超音波トランスデューサの第1の方向に活性化させることによって非合焦超音波エネルギを前記対象物の平坦領域に印加して、前記せん断波が前記平坦領域から外側に延びる方向に沿って伝搬するようにした工程が含まれることを特徴とする請求項1に記載の方法。
- 前記検出器が超音波装置とされ、かつ、
前記ロ)の工程において、複数の超音波トランスデューサ構成要素を超音波トランスデューサの前記第1の方向に直交する第2の方向に沿って活性させることによって、前記対象物の少なくとも1箇所に超音波エネルギを印加して、前記測定情報を取得することを特徴とする請求項10に記載の方法。 - 前記工程イ)で用いられる超音波トランスデューサが、前記ロ)の工程で用いられる前記超音波トランスデューサと異なっていることを特徴とする請求項11に記載の方法。
- 前記イ)の工程には、少なくとも2つの非合焦超音波ビームを前記対象物に印加する工程が含まれることを特徴とする請求項1に記載の装置。
- 前記検出器が超音波装置とされ、かつ前記ロ)の工程で前記対象物に超音波エネルギを印加することで前記測定情報を取得し、
前記イ)の工程には、前記対象物に複数の非合焦超音波トーンバーストを印加する工程が含まれ、
前記ロ)の工程には、前記イ)の工程で印加される複数の非合焦超音波トーンバーストと時間的にインタレースされた複数の超音波トーンバーストを印加する工程が含まれる
ことを特徴とする請求項1に記載の装置。 - 前記イ)の工程で印加される非合焦超音波エネルギが、超音波トランスデューサによって該超音波トランスデューサの表面に対する角度で生成されることを特徴とする請求項1に記載の装置。
- 対象物の機械的特性を超音波で測定する方法であって、
イ)軸方向の複数の深度において複数の細胞変形を生成するために、非合焦超音波エネルギを対象物に印加する工程と、
ロ)前記対象物の中の、前記複数の細胞変形のうちの少なくとも1つが配置されている少なくとも1箇所に、超音波エネルギを印加することによって、前記対象物から測定情報を取得する工程と、
ハ)前記ロ)の工程で取得した測定情報を用いて前記対象物の機械的特性を算出する工程と、
を含むことを特徴とする方法。 - 前記ロ)の工程で印加する超音波エネルギが、合焦超音波エネルギおよび非合焦超音波エネルギの少なくとも1つとされることを特徴とする請求項16に記載の方法。
- 前記複数の細胞変形に、複数のせん断波が含まれていることを特徴とする請求項16に記載の方法。
- 超音波トランスデューサを有する超音波装置で対象物の機械的特性を測定する方法であって、
イ)前記超音波エネルギが前記超音波トランスデューサの表面に実質的に直交する方向に力を発生するように、前記対象物に超音波エネルギを印加することによって、前記超音波トランスデューサから外側に延びる少なくとも1つの方向に前記対象物に伝搬するせん断波を前記超音波トランスデューサで生成する工程と、
ロ)前記イ)の工程で生成されたせん断波の存在する対象物の少なくとも1箇所に超音波エネルギを印加することによって測定情報を取得する工程と、
ハ)前記ロ)の工程で取得した測定情報を用いて前記対象物の機械的特性を算出する工程と、
を含むことを特徴とする方法。 - 前記イ)の工程で印加する前記超音波エネルギが、合焦超音波エネルギおよび非合焦超音波エネルギのうちの少なくとも1つであることを特徴とする請求項19に記載の方法。
- 前記イ)の工程で生成される前記せん断波が前記超音波トランスデューサの表面に実質的に直交する方向に伝搬することを特徴とする請求項19に記載の方法。
- 前記イ)の工程で生成される前記せん断波の少なくとも1つが前記超音波トランスデューサの表面の1箇所から径方向に伝搬するせん断波とされることを特徴とする請求項19に記載の方法。
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US201161446839P | 2011-02-25 | 2011-02-25 | |
US61/446,839 | 2011-02-25 | ||
PCT/US2012/026769 WO2012116364A1 (en) | 2011-02-25 | 2012-02-27 | Ultrasound vibrometry with unfocused ultrasound |
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WO2012116364A1 (en) | 2012-08-30 |
CN103492855B (zh) | 2016-03-30 |
BR112013021791A2 (pt) | 2016-10-18 |
EP2678658A4 (en) | 2018-01-10 |
US20140046173A1 (en) | 2014-02-13 |
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BR112013021791B1 (pt) | 2020-11-17 |
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US11172910B2 (en) | 2021-11-16 |
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