JP2014501518A5 - - Google Patents
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- Publication number
- JP2014501518A5 JP2014501518A5 JP2013543140A JP2013543140A JP2014501518A5 JP 2014501518 A5 JP2014501518 A5 JP 2014501518A5 JP 2013543140 A JP2013543140 A JP 2013543140A JP 2013543140 A JP2013543140 A JP 2013543140A JP 2014501518 A5 JP2014501518 A5 JP 2014501518A5
- Authority
- JP
- Japan
- Prior art keywords
- myumyu
- chelerythrine
- ivermectin
- culturing
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LLEJIEBFSOEYIV-UHFFFAOYSA-N Chelerythrine Chemical compound C1=C2OCOC2=CC2=CC=C3C4=CC=C(OC)C(OC)=C4C=[N+](C)C3=C21 LLEJIEBFSOEYIV-UHFFFAOYSA-N 0.000 claims 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N caffeic acid Natural products OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 claims 2
- AZSNMRSAGSSBNP-XPNPUAGNSA-N 22,23-dihydroavermectin B1a Chemical compound C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 AZSNMRSAGSSBNP-XPNPUAGNSA-N 0.000 claims 1
- 229960002418 Ivermectin Drugs 0.000 claims 1
- 229940074360 caffeic acid Drugs 0.000 claims 1
- 235000004883 caffeic acid Nutrition 0.000 claims 1
- 239000006143 cell culture media Substances 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
Claims (1)
- 少なくとも１μΜのコーヒー酸、少なくとも１μΜのイベルメクチン及び少なくとも５μΜ塩化ケレリトリンから選択される１種以上を含む細胞培養培地で前記細胞集団を培養する、請求項１〜４のいずれか１項に記載の方法。
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2010/059586 WO2012078153A1 (en) | 2010-12-08 | 2010-12-08 | Agents and methods for inhibiting human pluripotent stem cell growth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501518A JP2014501518A (ja) | 2014-01-23 |
| JP2014501518A5 true JP2014501518A5 (ja) | 2014-03-13 |
| JP5875597B2 JP5875597B2 (ja) | 2016-03-02 |
Family
ID=46207417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013543140A Expired - Fee Related JP5875597B2 (ja) | 2010-12-08 | 2010-12-08 | ヒト万能性幹細胞の成長を阻害する薬剤および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9365830B2 (ja) |
| EP (1) | EP2649177B1 (ja) |
| JP (1) | JP5875597B2 (ja) |
| CN (1) | CN103354835B (ja) |
| AU (1) | AU2010365057B2 (ja) |
| CA (1) | CA2820419A1 (ja) |
| ES (1) | ES2690663T3 (ja) |
| WO (1) | WO2012078153A1 (ja) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9238080B2 (en) | 2010-05-21 | 2016-01-19 | Merrimack Pharmaceuticals, Inc. | Bi-specific fusion proteins |
| US20140234963A1 (en) | 2011-06-21 | 2014-08-21 | Novo Nordisk A/S | Efficient induction of definitive endoderm from pluripotent stem cells |
| EP2980207B1 (en) | 2013-03-25 | 2018-12-05 | Foundation for Biomedical Research and Innovation at Kobe | Cell sorting method |
| CN105283541B (zh) * | 2013-05-30 | 2019-02-19 | 味之素株式会社 | 干细胞培养用培养基 |
| US10501724B2 (en) * | 2013-08-23 | 2019-12-10 | Sumitomo Chemical Company, Limited | Method for producing retinal tissue and retina-related cells |
| JP6791756B2 (ja) | 2014-01-21 | 2020-11-25 | ザ メディカル カレッジ オブ ウィスコンシン インクＴｈｅ Ｍｅｄｉｃａｌ Ｃｏｌｌｅｇｅ Ｏｆ Ｗｉｓｃｏｎｓｉｎ， Ｉｎｃ． | 多能性幹細胞の選択的な阻害のための方法 |
| KR20160142340A (ko) * | 2014-03-31 | 2016-12-12 | 아지노모토 가부시키가이샤 | 간세포용 배지 |
| KR102142364B1 (ko) * | 2015-08-13 | 2020-08-07 | 베이하오 스템 셀 앤 리제너레이티브 메디슨 리서치 인스티 튜트 씨오.,엘티디. | 유도 연장 만능 줄기 세포, 이의 제조방법 및 사용 방법 |
| US10040840B2 (en) | 2015-10-02 | 2018-08-07 | Silver Creek Pharmaceuticals, Inc. | Bi-specific annexin A5/IGF-1 proteins and methods of use thereof to promote regeneration and survival of tissue |
| WO2018140647A1 (en) * | 2017-01-25 | 2018-08-02 | Cedars-Sinai Medical Center | In vitro induction of mammary-like differentiation from human pluripotent stem cells |
| KR102448428B1 (ko) * | 2017-01-27 | 2022-09-30 | 가부시키가이샤 가네카 | 내배엽계 세포 집단, 및 다능성 세포로부터 3배엽 중 어느 하나의 세포 집단을 제조하는 방법 |
| CA3055213A1 (en) * | 2017-03-07 | 2018-09-13 | Platelet Biogenesis, Inc. | Recirculating bioreactor |
| US11767513B2 (en) | 2017-03-14 | 2023-09-26 | Cedars-Sinai Medical Center | Neuromuscular junction |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| JP7298844B2 (ja) | 2017-06-05 | 2023-06-27 | テルモ株式会社 | 細胞培養物の製造方法 |
| US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
| CN108570443A (zh) * | 2017-12-05 | 2018-09-25 | 皓昇莱生物制药有限公司 | 一种用于培养尿液来源细胞的培养基 |
| WO2019195800A1 (en) | 2018-04-06 | 2019-10-10 | Cedars-Sinai Medical Center | Novel differentiation technique to generate dopaminergic neurons from induced pluripotent stem cells |
| CN110684714B (zh) * | 2018-07-05 | 2023-05-09 | 广东博溪生物科技有限公司 | 一种屏障功能弱化模型的构建方法 |
| CN112739812A (zh) * | 2018-07-19 | 2021-04-30 | 血小板生源说股份有限公司 | 堆叠的再循环生物反应器 |
| US10724052B2 (en) | 2018-09-07 | 2020-07-28 | Crispr Therapeutics Ag | Universal donor cells |
| KR20210060446A (ko) * | 2018-09-19 | 2021-05-26 | 다케다 야쿠힌 고교 가부시키가이샤 | 인슐린 산생 세포 |
| EP3739040B1 (en) | 2018-09-27 | 2023-07-05 | Osaka University | Sheeting method for pluripotent stem cell-derived cells |
| EP3901252A4 (en) * | 2018-12-21 | 2022-10-26 | National University Corporation Hokkaido University | COMPOSITION FOR ELIMINATING PLURIPOTENT STEM CELLS AND METHOD FOR ELIMINATING PLURIPOTENT STEM CELLS |
| CN110373375A (zh) * | 2019-03-19 | 2019-10-25 | 杭州原生生物科技有限公司 | 一种制备纤维细胞作为细胞培养基的方法和用途 |
| BR112022004026A2 (pt) | 2019-09-05 | 2022-08-16 | Crispr Therapeutics Ag | Células doadoras universais |
| US11116797B2 (en) | 2019-09-05 | 2021-09-14 | Crispr Therapeutics Ag | Universal donor cells |
| EP4196611A1 (en) | 2020-08-15 | 2023-06-21 | Regeneron Pharmaceuticals, Inc. | Treatment of obesity in subjects having variant nucleic acid molecules encoding calcitonin receptor (calcr) |
| WO2022144855A1 (en) | 2020-12-31 | 2022-07-07 | Crispr Therapeutics Ag | Universal donor cells |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5861483A (en) * | 1996-04-03 | 1999-01-19 | Pro-Neuron, Inc. | Inhibitor of stem cell proliferation and uses thereof |
| WO2000027995A1 (en) | 1998-11-09 | 2000-05-18 | Monash University | Embryonic stem cells |
| US8597947B2 (en) * | 2004-12-29 | 2013-12-03 | Hadasit Medical Research Services & Development Limited | Undifferentiated stem cell culture systems |
| US20080070303A1 (en) * | 2005-11-21 | 2008-03-20 | West Michael D | Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby |
| WO2011011632A1 (en) * | 2009-07-22 | 2011-01-27 | Tufts University | Methods and compositions for modulating membrane potential to influence cell behavior |
-
2010
- 2010-12-08 US US13/992,931 patent/US9365830B2/en not_active Expired - Fee Related
- 2010-12-08 WO PCT/US2010/059586 patent/WO2012078153A1/en active Application Filing
- 2010-12-08 JP JP2013543140A patent/JP5875597B2/ja not_active Expired - Fee Related
- 2010-12-08 EP EP10860584.1A patent/EP2649177B1/en not_active Not-in-force
- 2010-12-08 AU AU2010365057A patent/AU2010365057B2/en not_active Ceased
- 2010-12-08 CN CN201080071181.7A patent/CN103354835B/zh not_active Expired - Fee Related
- 2010-12-08 ES ES10860584.1T patent/ES2690663T3/es active Active
- 2010-12-08 CA CA2820419A patent/CA2820419A1/en not_active Abandoned
-
2016
- 2016-06-10 US US15/178,852 patent/US20160281058A1/en not_active Abandoned
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