JP2014500885A5 - - Google Patents
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- Publication number
- JP2014500885A5 JP2014500885A5 JP2013541447A JP2013541447A JP2014500885A5 JP 2014500885 A5 JP2014500885 A5 JP 2014500885A5 JP 2013541447 A JP2013541447 A JP 2013541447A JP 2013541447 A JP2013541447 A JP 2013541447A JP 2014500885 A5 JP2014500885 A5 JP 2014500885A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- compound according
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 29
- 150000003839 salts Chemical class 0.000 claims 14
- 208000010877 cognitive disease Diseases 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 claims 2
- 208000028698 Cognitive impairment Diseases 0.000 claims 2
- 208000008238 Muscle Spasticity Diseases 0.000 claims 2
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 201000000980 schizophrenia Diseases 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000019901 Anxiety disease Diseases 0.000 claims 1
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 claims 1
- 206010003805 Autism Diseases 0.000 claims 1
- 208000020706 Autistic disease Diseases 0.000 claims 1
- 208000020925 Bipolar disease Diseases 0.000 claims 1
- 201000006474 Brain Ischemia Diseases 0.000 claims 1
- 206010048962 Brain oedema Diseases 0.000 claims 1
- 206010008120 Cerebral ischaemia Diseases 0.000 claims 1
- 208000027691 Conduct disease Diseases 0.000 claims 1
- 206010010904 Convulsion Diseases 0.000 claims 1
- 206010011878 Deafness Diseases 0.000 claims 1
- 206010012289 Dementia Diseases 0.000 claims 1
- 208000012661 Dyskinesia Diseases 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 206010019196 Head injury Diseases 0.000 claims 1
- 208000010496 Heart Arrest Diseases 0.000 claims 1
- 208000023105 Huntington disease Diseases 0.000 claims 1
- 208000019695 Migraine disease Diseases 0.000 claims 1
- 208000019022 Mood disease Diseases 0.000 claims 1
- 208000037212 Neonatal hypoxic and ischemic brain injury Diseases 0.000 claims 1
- 208000012902 Nervous system disease Diseases 0.000 claims 1
- 208000025966 Neurological disease Diseases 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000028017 Psychotic disease Diseases 0.000 claims 1
- 208000017442 Retinal disease Diseases 0.000 claims 1
- 206010038923 Retinopathy Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 claims 1
- 208000009205 Tinnitus Diseases 0.000 claims 1
- 206010044565 Tremor Diseases 0.000 claims 1
- 206010046543 Urinary incontinence Diseases 0.000 claims 1
- 206010047700 Vomiting Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 1
- 230000036506 anxiety Effects 0.000 claims 1
- 208000006752 brain edema Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 206010008118 cerebral infarction Diseases 0.000 claims 1
- 230000007882 cirrhosis Effects 0.000 claims 1
- 208000019425 cirrhosis of liver Diseases 0.000 claims 1
- 230000019771 cognition Effects 0.000 claims 1
- 231100000895 deafness Toxicity 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 206010015037 epilepsy Diseases 0.000 claims 1
- 231100000040 eye damage Toxicity 0.000 claims 1
- 208000016354 hearing loss disease Diseases 0.000 claims 1
- 230000002218 hypoglycaemic effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 208000035231 inattentive type attention deficit hyperactivity disease Diseases 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 206010027599 migraine Diseases 0.000 claims 1
- 230000000926 neurological effect Effects 0.000 claims 1
- 230000003961 neuronal insult Effects 0.000 claims 1
- 208000033300 perinatal asphyxia Diseases 0.000 claims 1
- 208000020016 psychiatric disease Diseases 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 210000000278 spinal cord Anatomy 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 231100000886 tinnitus Toxicity 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
- 206010044652 trigeminal neuralgia Diseases 0.000 claims 1
- 230000008673 vomiting Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41879110P | 2010-12-01 | 2010-12-01 | |
| US61/418,791 | 2010-12-01 | ||
| US41923210P | 2010-12-02 | 2010-12-02 | |
| US61/419,232 | 2010-12-02 | ||
| PCT/IB2011/055190 WO2012073146A1 (en) | 2010-12-01 | 2011-11-18 | Kat ii inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014500885A JP2014500885A (ja) | 2014-01-16 |
| JP2014500885A5 true JP2014500885A5 (enExample) | 2014-12-18 |
| JP5868994B2 JP5868994B2 (ja) | 2016-02-24 |
Family
ID=45315857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013541447A Expired - Fee Related JP5868994B2 (ja) | 2010-12-01 | 2011-11-18 | Ｋａｔｉｉ阻害剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8487104B2 (enExample) |
| EP (1) | EP2646417A1 (enExample) |
| JP (1) | JP5868994B2 (enExample) |
| KR (1) | KR101522803B1 (enExample) |
| CN (1) | CN103228631B (enExample) |
| AR (1) | AR084051A1 (enExample) |
| AU (1) | AU2011336217B2 (enExample) |
| CA (1) | CA2819106C (enExample) |
| IL (1) | IL226668A (enExample) |
| MX (1) | MX2013005915A (enExample) |
| SG (1) | SG190246A1 (enExample) |
| WO (1) | WO2012073146A1 (enExample) |
| ZA (1) | ZA201303412B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2861593A1 (en) * | 2012-06-15 | 2015-04-22 | Pfizer Inc. | Tricyclic compounds as kat ii inhibitors |
| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| TWI693227B (zh) * | 2014-04-23 | 2020-05-11 | 日商田邊三菱製藥股份有限公司 | 新穎二環性或三環性雜環化合物 |
| EA034167B8 (ru) | 2015-05-22 | 2021-04-27 | Эйджинбайо, Инк. | Фармацевтические композиции леветирацетама пролонгированного высвобождения |
| EP3372601B1 (en) | 2015-10-22 | 2022-09-21 | Mitsubishi Tanabe Pharma Corporation | Novel bicyclic heterocyclic compound |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4208304A1 (de) * | 1992-03-16 | 1993-09-23 | Merck Patent Gmbh | 2-oxochinolinderivate |
| US5594006A (en) * | 1993-03-18 | 1997-01-14 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives as matrix metalloproteinases inhibitors |
| JPH0881443A (ja) * | 1994-09-12 | 1996-03-26 | Otsuka Pharmaceut Co Ltd | 細胞外マトリックス金属プロテアーゼ阻害剤 |
| WO2005007628A1 (en) * | 2003-07-11 | 2005-01-27 | Bristol-Myers Squibb Company | Tetrahydroquinoline derivatives as cannabinoid receptor modulators |
| US20100273787A1 (en) * | 2007-11-15 | 2010-10-28 | Robert Schwarcz | Kynurenine-aminotransferase inhibitors |
| JP5643818B2 (ja) * | 2009-06-18 | 2014-12-17 | ファイザー・インク | Ｋａｔｉｉ阻害剤としての二環式および三環式化合物 |
| DK2646443T3 (en) | 2010-12-01 | 2014-11-17 | Pfizer | CAT-II inhibitors |
-
2011
- 2011-11-18 WO PCT/IB2011/055190 patent/WO2012073146A1/en not_active Ceased
- 2011-11-18 EP EP11794240.9A patent/EP2646417A1/en not_active Withdrawn
- 2011-11-18 AU AU2011336217A patent/AU2011336217B2/en not_active Ceased
- 2011-11-18 MX MX2013005915A patent/MX2013005915A/es not_active Application Discontinuation
- 2011-11-18 KR KR1020137016959A patent/KR101522803B1/ko not_active Expired - Fee Related
- 2011-11-18 JP JP2013541447A patent/JP5868994B2/ja not_active Expired - Fee Related
- 2011-11-18 CA CA2819106A patent/CA2819106C/en not_active Expired - Fee Related
- 2011-11-18 CN CN201180057792.0A patent/CN103228631B/zh not_active Expired - Fee Related
- 2011-11-18 SG SG2013036314A patent/SG190246A1/en unknown
- 2011-11-30 AR ARP110104458A patent/AR084051A1/es not_active Application Discontinuation
- 2011-11-30 US US13/307,140 patent/US8487104B2/en not_active Expired - Fee Related
-
2013
- 2013-05-10 ZA ZA2013/03412A patent/ZA201303412B/en unknown
- 2013-05-30 IL IL226668A patent/IL226668A/en not_active IP Right Cessation
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