JP2014221816A5 - - Google Patents
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- Publication number
- JP2014221816A5 JP2014221816A5 JP2014148568A JP2014148568A JP2014221816A5 JP 2014221816 A5 JP2014221816 A5 JP 2014221816A5 JP 2014148568 A JP2014148568 A JP 2014148568A JP 2014148568 A JP2014148568 A JP 2014148568A JP 2014221816 A5 JP2014221816 A5 JP 2014221816A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polymer
- poly
- cellulose
- excipients
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95704407P | 2007-08-21 | 2007-08-21 | |
| US60/957,044 | 2007-08-21 | ||
| US5092208P | 2008-05-06 | 2008-05-06 | |
| US61/050,922 | 2008-05-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Division JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014221816A JP2014221816A (ja) | 2014-11-27 |
| JP2014221816A5 true JP2014221816A5 (https=) | 2015-01-15 |
Family
ID=40378995
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Active JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
| JP2014148568A Withdrawn JP2014221816A (ja) | 2007-08-21 | 2014-07-22 | 医薬品適用のための熱−動力学的混合 |
| JP2016076558A Withdrawn JP2016121195A (ja) | 2007-08-21 | 2016-04-06 | 医薬品適用のための熱−動力学的混合 |
| JP2018226362A Withdrawn JP2019052173A (ja) | 2007-08-21 | 2018-12-03 | 医薬品適用のための熱−動力学的混合 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Active JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016076558A Withdrawn JP2016121195A (ja) | 2007-08-21 | 2016-04-06 | 医薬品適用のための熱−動力学的混合 |
| JP2018226362A Withdrawn JP2019052173A (ja) | 2007-08-21 | 2018-12-03 | 医薬品適用のための熱−動力学的混合 |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US8486423B2 (https=) |
| EP (1) | EP2187968A4 (https=) |
| JP (4) | JP6073043B2 (https=) |
| CN (1) | CN101835492B (https=) |
| CA (3) | CA2990445C (https=) |
| WO (1) | WO2009026461A2 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2155167A2 (en) | 2007-06-04 | 2010-02-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| US9545361B1 (en) * | 2011-07-25 | 2017-01-17 | Dispersol Technologies, Llc | Multiple speed process for preserving heat sensitive portions of a thermokinetically melt blended batch |
| JP6073043B2 (ja) | 2007-08-21 | 2017-02-01 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 医薬品適用のための熱−動力学的混合 |
| EA020954B1 (ru) | 2008-06-16 | 2015-03-31 | Бинд Терапьютикс, Инк. | Загруженные лекарственным средством полимерные наночастицы, фармацевтическая композиция и способ лечения рака |
| US8318211B2 (en) | 2008-06-16 | 2012-11-27 | Bind Biosciences, Inc. | Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same |
| WO2010005726A2 (en) * | 2008-06-16 | 2010-01-14 | Bind Biosciences Inc. | Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same |
| HUE032158T2 (en) * | 2008-10-31 | 2017-09-28 | Univ Mississippi | Process for the preparation of delta9-THC amino acid esters |
| US8563041B2 (en) * | 2008-12-12 | 2013-10-22 | Bind Therapeutics, Inc. | Therapeutic particles suitable for parenteral administration and methods of making and using same |
| JP2012512175A (ja) | 2008-12-15 | 2012-05-31 | バインド バイオサイエンシズ インコーポレイテッド | 治療薬を徐放するための長時間循環性ナノ粒子 |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| NZ597283A (en) | 2009-06-24 | 2013-07-26 | Egalet Ltd | Controlled release formulations |
| DK2509634T3 (en) | 2009-12-11 | 2019-04-23 | Pfizer | Stable formulations for lyophilization of therapeutic particles |
| EP2515942B1 (en) | 2009-12-15 | 2020-02-12 | Pfizer Inc. | Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers |
| WO2012116238A1 (en) * | 2011-02-23 | 2012-08-30 | Dispersol Technologies, Llc | PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-β-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS |
| CN102204868B (zh) * | 2011-05-18 | 2014-01-22 | 北京化工大学 | 采用多元辅料制备吲哚美辛速释制剂的热熔挤出工艺 |
| US9821283B1 (en) * | 2011-07-25 | 2017-11-21 | Dispersol Technologies, Llc | Direct probe sensed temperature method for speed change for heat sensitive portions of a thermokinetically melt blended batch |
| WO2014043618A1 (en) | 2012-09-17 | 2014-03-20 | Bind Therapeutics, Inc. | Process for preparing therapeutic nanoparticles |
| EP3089736B1 (en) * | 2013-12-31 | 2025-07-23 | Ascendia Pharmaceuticals, LLC | Pharmaceutical compositions for poorly water-soluble compounds |
| PE20170312A1 (es) | 2014-03-14 | 2017-03-30 | Pfizer | Nanoparticulas terapeuticas que comprenden un agente terapeutico, y metodos para su elaboracion y uso |
| CN106232144B (zh) * | 2014-03-18 | 2019-12-06 | 武田药品工业株式会社 | 固体分散体 |
| CN106413870A (zh) * | 2014-04-18 | 2017-02-15 | 分散技术有限责任公司 | 用于保护热动力学熔体共混批次的热敏部分的多级速度加工 |
| US20170333404A1 (en) * | 2014-11-03 | 2017-11-23 | Dispersol Technologies, Llc | Improved formulations of vemurafenib and methods of making the same |
| EP3247334A1 (en) * | 2015-01-20 | 2017-11-29 | Merck Patent GmbH | Solid dispersions of compounds using polyvinyl alcohol as a carrier polymer |
| MA43271A (fr) | 2015-06-17 | 2018-09-26 | Dispersol Technologies Llc | Formulations améliorées de déférasirox et leurs procédés de fabrication |
| TWI799366B (zh) | 2015-09-15 | 2023-04-21 | 美商建南德克公司 | 胱胺酸結骨架平臺 |
| CN109069460A (zh) * | 2016-05-09 | 2018-12-21 | 分散技术有限责任公司 | 改进的药物制剂 |
| ES3048691T3 (en) | 2016-05-13 | 2025-12-11 | Merck Patent Gmbh | Particle size and distribution of polymer for melt extrusion application |
| JP7376220B2 (ja) * | 2017-09-11 | 2023-11-08 | オースティンピーエックス リミテッド ライアビリティ カンパニー | 熱動力学的に溶融ブレンドされるバッチの熱感受性部分用の、直接プローブにより感知した温度による、速度変更のための方法 |
| WO2019060525A1 (en) * | 2017-09-22 | 2019-03-28 | Dispersol Technologies, Llc | PHARMACEUTICAL FORMULATIONS OF CYCLIC OLIGOMER AND ABIRATERONE AND METHODS OF FORMATION AND ADMINISTRATION THEREOF |
| EP3470133B1 (en) | 2017-10-13 | 2020-09-16 | Dispersol Technologies, LLC | Direct probe sensed temperature method for speed change for heat sensitive portions of a thermokinetically melt blended batch |
| CN109663524B (zh) * | 2017-10-13 | 2022-07-15 | 分散技术有限责任公司 | 用于热动力学熔体共混批次的热敏部分的速度改变的直接进样探头感测温度方法 |
| CN111511365A (zh) * | 2017-11-10 | 2020-08-07 | 分散技术有限责任公司 | 改进的药物制剂 |
| EP3492070A1 (en) * | 2017-11-30 | 2019-06-05 | BIT Pharma GmbH | Process and device for preparing a solid dispersion |
| MX2020006518A (es) * | 2017-12-21 | 2020-10-28 | Danisco Us Inc | Gránulos de fusión en caliente, que contienen enzimas, que comprenden un desecante termotolerante. |
| US20200147032A1 (en) | 2018-11-14 | 2020-05-14 | Robert K. Prud'homme | Dihydromyricetin hot melt extrusion formulations and methods for forming them |
| US20220401579A1 (en) * | 2019-11-30 | 2022-12-22 | Dispersol Technologies, Llc | Inclusion complexes of pharmaceuticals and cyclic oligomers |
| KR20220130698A (ko) * | 2019-12-20 | 2022-09-27 | 에피자임, 인코포레이티드 | Ezh2 억제제의 결정질 하이드로브로마이드 염, 이의 제조 및 암의 치료에 유용한 약학적 조성물 |
| AU2021248406A1 (en) | 2020-04-01 | 2022-10-13 | Board Of Regents, The University Of Texas System | Pharmaceutical compositions of niclosamide |
| CA3203975A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| EP4259143A4 (en) * | 2020-12-11 | 2024-11-13 | Board of Regents, The University of Texas System | COMPOSITIONS AND METHODS FOR MANUFACTURING COCRYSTALS BY DIELECTRIC HEATING WITH DISPERSIVE AND DISTRIBUTIVE MIXTURE |
| WO2022207775A1 (en) * | 2021-04-01 | 2022-10-06 | Merck Patent Gmbh | Process for continuous hot melt granulation of low soluble pharmaceuticals |
| CA3216359A1 (en) | 2021-04-07 | 2022-10-13 | Battelle Memorial Institute | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers |
| US20250000794A1 (en) * | 2021-07-27 | 2025-01-02 | Board Of Regents, The University Of Texas System | Improved drug processing methods to increase drug loading |
| US20230112800A1 (en) | 2021-08-31 | 2023-04-13 | Board Of Regents, The University Of Texas System | Delayed release niclosamide formulation |
| AU2024353375A1 (en) | 2023-09-29 | 2026-04-09 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
| CN119453203A (zh) * | 2025-01-09 | 2025-02-18 | 山东百农思达生物科技有限公司 | 一种含杀虫单和阿维菌素的复合微乳制剂及其制备工艺 |
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| FR2319478A1 (fr) | 1975-07-30 | 1977-02-25 | Gen Electric | Extrudeuse et procede d'extrusion de materiaux thermoplastiques |
| US4230615A (en) * | 1978-11-21 | 1980-10-28 | Carlew Chemicals Limited | Process for controlled mixing in a high intensity mixer |
| US4628073A (en) | 1984-10-03 | 1986-12-09 | Monsanto Company | Soft, rubbery, multiphase matrix material and methods for its production |
| US4789597A (en) | 1987-01-12 | 1988-12-06 | Fetherstonhaugh & Co. | Incorporation of chemically reactive agents on resin particles |
| WO1992018106A1 (fr) * | 1991-04-16 | 1992-10-29 | Nippon Shinyaku Co., Ltd. | Procede de production d'une dispersion solide |
| JP2516524B2 (ja) * | 1992-04-27 | 1996-07-24 | 大洋薬品工業株式会社 | 持続性製剤 |
| JPH07159587A (ja) | 1993-12-07 | 1995-06-23 | Hitachi Ltd | 樹脂性能モニタ |
| JPH07187998A (ja) * | 1993-12-27 | 1995-07-25 | Kao Corp | 錠剤の製造方法 |
| GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
| US5895790A (en) | 1995-03-14 | 1999-04-20 | Good; Elmer | Thermosetting wide range polymer blends |
| DE19531067A1 (de) | 1995-08-23 | 1997-02-27 | Hermann P T Prof Dr Med Ammon | Verwendung von Boswelliasäure und ihren Derivaten zur Hemmung der normalen und gesteigerten Leukozytenelastase- oder Plasminaktivität |
| WO1997044014A1 (en) * | 1996-05-20 | 1997-11-27 | Janssen Pharmaceutica N.V. | Antifungal compositions with improved bioavailability |
| US20010053791A1 (en) | 2000-03-16 | 2001-12-20 | Babcock Walter C. | Glycogen phosphorylase inhibitor |
| US6709146B1 (en) | 2000-07-28 | 2004-03-23 | David Little | Thermokinetic mixer and method of using |
| OA12625A (en) * | 2001-06-22 | 2006-06-12 | Pfizer Prod Inc | Pharmaceutical compositions of adsorbates of amorphous drug. |
| KR20040011248A (ko) * | 2002-07-30 | 2004-02-05 | 환인제약 주식회사 | 암로디핀의 고체분산체와 그 제조방법 및 그를 포함하는약학적 조성물 |
| CN100594023C (zh) | 2003-02-03 | 2010-03-17 | 诺瓦提斯公司 | 药物制剂 |
| GB0319797D0 (en) * | 2003-08-26 | 2003-09-24 | Leuven K U Res & Dev | Particle size reduction of poorly soluble drugs |
| US20050158376A1 (en) * | 2003-10-23 | 2005-07-21 | Sardi William F. | Dietary supplement and method of processing same |
| CN100563658C (zh) | 2003-11-14 | 2009-12-02 | 味之素株式会社 | 苯丙氨酸衍生物的固体分散体或固体分散体医药制剂 |
| US20050258288A1 (en) | 2003-11-26 | 2005-11-24 | E. I. Du Pont De Nemours And Company | High pressure media milling system and process of forming particles |
| JP2005263758A (ja) * | 2004-03-22 | 2005-09-29 | Kirin Brewery Co Ltd | 非晶質のn−{2−クロロ−4−[(6,7−ジメトキシ−4−キナゾリニル)オキシ]フェニル}−n’−プロピルウレア |
| KR101086254B1 (ko) | 2004-11-04 | 2011-11-24 | 에스케이케미칼주식회사 | 생체이용률이 개선된 프란루카스트 고체분산체 조성물 및그 고체분산체의 제조방법 |
| EP1865929A2 (en) | 2005-03-28 | 2007-12-19 | Bioresponse, L.L.C. | Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health |
| JP2006347939A (ja) * | 2005-06-15 | 2006-12-28 | Tokyo Printing Ink Mfg Co Ltd | 薬物高分子複合体の製造方法及び薬物高分子複合体 |
| JP4429262B2 (ja) * | 2005-12-09 | 2010-03-10 | 壽製薬株式会社 | フェノフィブラートの固体分散体 |
| JP6073043B2 (ja) * | 2007-08-21 | 2017-02-01 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 医薬品適用のための熱−動力学的混合 |
| US9545361B1 (en) * | 2011-07-25 | 2017-01-17 | Dispersol Technologies, Llc | Multiple speed process for preserving heat sensitive portions of a thermokinetically melt blended batch |
| JP2012047227A (ja) | 2010-08-25 | 2012-03-08 | Nippon Steel & Sumikin Metal Products Co Ltd | ナット保持部材 |
| WO2012116238A1 (en) | 2011-02-23 | 2012-08-30 | Dispersol Technologies, Llc | PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-β-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS |
| US20170333404A1 (en) | 2014-11-03 | 2017-11-23 | Dispersol Technologies, Llc | Improved formulations of vemurafenib and methods of making the same |
-
2008
- 2008-08-21 JP JP2010522038A patent/JP6073043B2/ja active Active
- 2008-08-21 CN CN2008801123533A patent/CN101835492B/zh active Active
- 2008-08-21 EP EP08798412A patent/EP2187968A4/en not_active Ceased
- 2008-08-21 US US12/196,154 patent/US8486423B2/en active Active
- 2008-08-21 CA CA2990445A patent/CA2990445C/en active Active
- 2008-08-21 WO PCT/US2008/073913 patent/WO2009026461A2/en not_active Ceased
- 2008-08-21 CA CA2697099A patent/CA2697099C/en active Active
- 2008-08-21 CA CA3076115A patent/CA3076115C/en active Active
-
2013
- 2013-07-15 US US13/942,199 patent/US9339440B2/en active Active
-
2014
- 2014-07-22 JP JP2014148568A patent/JP2014221816A/ja not_active Withdrawn
-
2016
- 2016-04-06 JP JP2016076558A patent/JP2016121195A/ja not_active Withdrawn
- 2016-05-13 US US15/154,083 patent/US10022385B2/en active Active
-
2018
- 2018-06-19 US US16/012,025 patent/US10668085B2/en active Active
- 2018-12-03 JP JP2018226362A patent/JP2019052173A/ja not_active Withdrawn
-
2020
- 2020-05-05 US US16/866,676 patent/US11439650B2/en active Active
-
2022
- 2022-07-25 US US17/814,567 patent/US12023343B2/en active Active
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