JP2014205674A5 - - Google Patents
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- Publication number
- JP2014205674A5 JP2014205674A5 JP2014102751A JP2014102751A JP2014205674A5 JP 2014205674 A5 JP2014205674 A5 JP 2014205674A5 JP 2014102751 A JP2014102751 A JP 2014102751A JP 2014102751 A JP2014102751 A JP 2014102751A JP 2014205674 A5 JP2014205674 A5 JP 2014205674A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- amino acid
- acid residues
- variable domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000539 amino acid group Chemical group 0.000 claims 6
- 102000009524 Vascular Endothelial Growth Factor A Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 101000808011 Homo sapiens Vascular endothelial growth factor A Proteins 0.000 claims 1
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 102000058223 human VEGFA Human genes 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3971908P | 2008-03-26 | 2008-03-26 | |
| US61/039,719 | 2008-03-26 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011501758A Division JP5823858B2 (ja) | 2008-03-26 | 2008-10-08 | 抗ｖｅｇｆ抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014205674A JP2014205674A (ja) | 2014-10-30 |
| JP2014205674A5 true JP2014205674A5 (cg-RX-API-DMAC7.html) | 2015-03-12 |
Family
ID=41114205
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011501758A Active JP5823858B2 (ja) | 2008-03-26 | 2008-10-08 | 抗ｖｅｇｆ抗体 |
| JP2014102751A Pending JP2014205674A (ja) | 2008-03-26 | 2014-05-16 | 抗ｖｅｇｆ抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011501758A Active JP5823858B2 (ja) | 2008-03-26 | 2008-10-08 | 抗ｖｅｇｆ抗体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7803371B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2259795B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5823858B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101581244B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN102065888B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008353479B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0822556B1 (cg-RX-API-DMAC7.html) |
| CA (3) | CA2981887C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009120178A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3216803T (lt) | 2008-06-25 | 2020-06-10 | Novartis Ag | Stabilūs ir tirpūs antikūnai, slopinantys vegf |
| CN102002104A (zh) * | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
| JP2013508308A (ja) * | 2009-10-23 | 2013-03-07 | ガーバン インスティテュート オブ メディカル リサーチ | 修飾可変ドメイン分子、ならびにその産生および使用方法 |
| BR112013021863A2 (pt) | 2011-03-03 | 2016-11-22 | Apexigen Inc | anticorpos anti-receptor il-6 e métodos de uso |
| CN104650229A (zh) * | 2011-11-02 | 2015-05-27 | 埃派斯进有限公司 | 抗-kdr抗体和使用方法 |
| CN103417965B (zh) * | 2012-05-17 | 2018-04-13 | 江苏先声药业有限公司 | 一种含有抗vegf抗体的药物组合物 |
| CN103417964A (zh) * | 2012-05-17 | 2013-12-04 | 江苏先声药物研究有限公司 | 一种抗vegf抗体的用途 |
| CA2901226C (en) | 2013-02-18 | 2020-11-17 | Vegenics Pty Limited | Vascular endothelial growth factor binding proteins |
| CN105263959A (zh) * | 2013-12-31 | 2016-01-20 | 财团法人生物技术开发中心 | 抗vegf抗体及其用途 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| JP2018511300A (ja) * | 2015-01-16 | 2018-04-26 | アルダー・バイオファーマシューティカルズ・インコーポレーテッド | 抗糖タンパク質抗体及びその使用 |
| CN107849105B (zh) * | 2015-07-06 | 2021-09-17 | Ucb生物制药有限责任公司 | Tau结合抗体 |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521382D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| JP7088454B2 (ja) | 2015-12-30 | 2022-06-21 | コディアック サイエンシーズ インコーポレイテッド | 抗体および抗体複合体 |
| CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| KR20220093103A (ko) * | 2019-09-13 | 2022-07-05 | 어드메어 테라퓨틱스 소사이어티 | 항종양용해 바이러스 항원 항체 및 이의 사용 방법 |
| WO2021072265A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN120769866A (zh) * | 2022-12-29 | 2025-10-10 | Ltz治疗股份有限公司 | 抗CD79b抗体及其用途 |
| CN118344476B (zh) * | 2024-05-16 | 2024-11-15 | 武汉爱博泰克生物科技有限公司 | 人c反应蛋白单克隆抗体、抗体对和检测试剂或试剂盒及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000064946A2 (en) * | 1999-04-28 | 2000-11-02 | Board Of Regents, The University Of Texas System | Compositions and methods for cancer treatment by selectively inhibiting vegf |
| CN1299833A (zh) * | 1999-12-30 | 2001-06-20 | 华西医科大学口腔医学研究所 | 抗人血管内皮生长因子单链抗体及其制备方法 |
| US20040185040A1 (en) * | 2001-11-21 | 2004-09-23 | Celltech R & D Limited | Modulating immune responses |
| EP1539947A4 (en) * | 2002-08-15 | 2006-09-06 | Epitomics Inc | HUMANIZED RABBIT ANTIBODIES |
| WO2005016950A1 (en) * | 2003-08-07 | 2005-02-24 | Epitomics, Inc. | Methods for humanizing rabbit monoclonal antibodies |
| US7462697B2 (en) | 2004-11-08 | 2008-12-09 | Epitomics, Inc. | Methods for antibody engineering |
| US7431927B2 (en) | 2005-03-24 | 2008-10-07 | Epitomics, Inc. | TNFα-neutralizing antibodies |
| SI2752428T1 (sl) * | 2008-06-25 | 2020-03-31 | Novartis Ag | Humaniziranje zajčjih protiteles z uporabo univerzalnega ogrodja protitelesa |
| CN102002104A (zh) * | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
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2008
- 2008-10-08 CA CA2981887A patent/CA2981887C/en active Active
- 2008-10-08 AU AU2008353479A patent/AU2008353479B2/en active Active
- 2008-10-08 CN CN200880128968.5A patent/CN102065888B/zh active Active
- 2008-10-08 US US12/247,933 patent/US7803371B2/en active Active
- 2008-10-08 BR BRPI0822556-7A patent/BRPI0822556B1/pt active IP Right Grant
- 2008-10-08 WO PCT/US2008/011620 patent/WO2009120178A1/en not_active Ceased
- 2008-10-08 EP EP08873637.6A patent/EP2259795B1/en active Active
- 2008-10-08 CN CN201410106341.7A patent/CN103992405B/zh active Active
- 2008-10-08 CA CA2719400A patent/CA2719400C/en active Active
- 2008-10-08 KR KR1020107023342A patent/KR101581244B1/ko active Active
- 2008-10-08 JP JP2011501758A patent/JP5823858B2/ja active Active
- 2008-10-08 CA CA3053675A patent/CA3053675A1/en not_active Abandoned
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2010
- 2010-07-30 US US12/847,757 patent/US8088375B2/en active Active
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2014
- 2014-05-16 JP JP2014102751A patent/JP2014205674A/ja active Pending