JP2014139229A5 - - Google Patents
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- Publication number
- JP2014139229A5 JP2014139229A5 JP2014075596A JP2014075596A JP2014139229A5 JP 2014139229 A5 JP2014139229 A5 JP 2014139229A5 JP 2014075596 A JP2014075596 A JP 2014075596A JP 2014075596 A JP2014075596 A JP 2014075596A JP 2014139229 A5 JP2014139229 A5 JP 2014139229A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- botulinum toxin
- monosaccharide
- trisaccharide
- disaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72512605P | 2005-10-06 | 2005-10-06 | |
| US60/725,126 | 2005-10-06 | ||
| US11/524,683 | 2006-09-21 | ||
| US11/524,683 US8137677B2 (en) | 2005-10-06 | 2006-09-21 | Non-protein stabilized clostridial toxin pharmaceutical compositions |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012162277A Division JP5758856B2 (ja) | 2005-10-06 | 2012-07-23 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017010322A Division JP6235176B2 (ja) | 2005-10-06 | 2017-01-24 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014139229A JP2014139229A (ja) | 2014-07-31 |
| JP2014139229A5 true JP2014139229A5 (enExample) | 2015-04-23 |
Family
ID=37527018
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008534672A Expired - Fee Related JP5140595B2 (ja) | 2005-10-06 | 2006-10-04 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
| JP2012162277A Expired - Fee Related JP5758856B2 (ja) | 2005-10-06 | 2012-07-23 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
| JP2014075596A Pending JP2014139229A (ja) | 2005-10-06 | 2014-04-01 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
| JP2017010322A Expired - Fee Related JP6235176B2 (ja) | 2005-10-06 | 2017-01-24 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008534672A Expired - Fee Related JP5140595B2 (ja) | 2005-10-06 | 2006-10-04 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
| JP2012162277A Expired - Fee Related JP5758856B2 (ja) | 2005-10-06 | 2012-07-23 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017010322A Expired - Fee Related JP6235176B2 (ja) | 2005-10-06 | 2017-01-24 | 非タンパク質安定化クロストリジウム毒素医薬組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US8137677B2 (enExample) |
| EP (2) | EP2679217B1 (enExample) |
| JP (4) | JP5140595B2 (enExample) |
| KR (1) | KR101314952B1 (enExample) |
| AU (1) | AU2006299366B2 (enExample) |
| CA (1) | CA2602926C (enExample) |
| CY (1) | CY1117727T1 (enExample) |
| DK (1) | DK2679217T3 (enExample) |
| ES (1) | ES2580010T3 (enExample) |
| HU (1) | HUE027810T2 (enExample) |
| MX (1) | MX2007012062A (enExample) |
| NZ (1) | NZ562033A (enExample) |
| PL (1) | PL2679217T3 (enExample) |
| PT (1) | PT2679217T (enExample) |
| SI (1) | SI2679217T1 (enExample) |
| WO (1) | WO2007041664A1 (enExample) |
Families Citing this family (41)
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|---|---|---|---|---|
| US7780967B2 (en) * | 2000-02-08 | 2010-08-24 | Allergan, Inc. | Reduced toxicity Clostridial toxin pharmaceutical compositions |
| US8632785B2 (en) * | 2000-02-08 | 2014-01-21 | Allergan, Inc. | Clostridial toxin pharmaceutical composition containing a gelatin fragment |
| US7763663B2 (en) | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
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| KR100852824B1 (ko) * | 2004-07-26 | 2008-08-18 | 메르츠 파마 게엠베하 운트 코. 카가아 | 보툴리눔 신경독소를 포함하는 치료 조성물 |
| WO2006094263A2 (en) | 2005-03-03 | 2006-09-08 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| KR20130079645A (ko) | 2005-07-18 | 2013-07-10 | 유니버시티 오브 메사츄세츠 로웰 | 나노에멀젼 조성물 및 이의 제조 및 사용 방법 |
| US8323666B2 (en) * | 2005-08-01 | 2012-12-04 | Allergan, Inc. | Botulinum toxin compositions |
| US8168206B1 (en) * | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
| US8137677B2 (en) | 2005-10-06 | 2012-03-20 | Allergan, Inc. | Non-protein stabilized clostridial toxin pharmaceutical compositions |
| CN101374498A (zh) | 2005-12-01 | 2009-02-25 | 麻萨诸塞州洛厄尔大学 | 肉毒杆菌纳米乳液 |
| US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| WO2008070538A2 (en) | 2006-12-01 | 2008-06-12 | Anterios, Inc. | Micellar nanoparticles comprising botulinum toxin |
| SG10201607909WA (en) | 2006-12-01 | 2016-11-29 | Anterios Inc | Peptide nanoparticles and uses therefor |
| CN101765423B (zh) | 2007-05-31 | 2014-08-06 | 安特里奥公司 | 核酸纳米粒子和其用途 |
| US8617568B2 (en) * | 2007-07-10 | 2013-12-31 | Medy-Tox, Inc. | Pharmaceutical liquid composition of botulinum toxin with improved stability |
| EP2198007B1 (en) | 2007-09-14 | 2017-10-25 | Sanofi Pasteur Biologics, LLC | Pharmaceutical compositions containing clostridium difficile toxoids a and b |
| US9107815B2 (en) | 2008-02-22 | 2015-08-18 | Allergan, Inc. | Sustained release poloxamer containing pharmaceutical compositions |
| RU2535003C2 (ru) * | 2008-12-10 | 2014-12-10 | Аллерган, Инк. | Фармацевтические композиции токсина клостридий |
| ES2669020T3 (es) | 2008-12-31 | 2018-05-23 | Revance Therapeutics, Inc. | Formulaciones inyectables de toxina botulínica |
| EP2248518B1 (en) * | 2009-04-17 | 2013-01-16 | Merz Pharma GmbH & Co. KGaA | Formulation for stabilizing proteins, peptides or mixtures thereof. |
| ES2615281T3 (es) | 2009-06-24 | 2017-06-06 | Charles N.S. Soparkar | Suplementación con cinc para aumentar la capacidad de respuesta al tratamiento con metaloproteasa |
| JP6043627B2 (ja) | 2009-06-25 | 2016-12-14 | ルバンス セラピュティックス インク.Revance Therapeutics,Inc. | アルブミン非含有ボツリヌス毒素製剤 |
| EP2504878A4 (en) * | 2009-11-09 | 2014-01-08 | Enerdel Inc | SCALABLE BATTERY MODULE |
| AU2011316111B2 (en) * | 2010-10-12 | 2015-05-28 | Merz Pharma Gmbh & Co. Kgaa | Formulation suitable for stabilizing proteins, which is free of mammalian excipients |
| ES2636680T5 (es) * | 2011-03-31 | 2023-10-31 | Medy Tox Inc | Preparación liofilizada de toxina botulínica |
| KR20140147950A (ko) * | 2013-06-20 | 2014-12-31 | 서울대학교산학협력단 | 필러와 보틀리눔 독소를 포함하는 피부 주름, 노화 개선 또는 신경근육 관련 질환 치료용 조성물 |
| US9480731B2 (en) | 2013-12-12 | 2016-11-01 | Medy-Tox, Inc. | Long lasting effect of new botulinum toxin formulations |
| GB201407525D0 (en) * | 2014-04-29 | 2014-06-11 | Syntaxin Ltd | Manufacture of recombinant clostridium botulinum neurotoxins |
| TWI688392B (zh) | 2014-07-07 | 2020-03-21 | 美商救生筏生物科技公司 | 無長循環材料之泊洛沙姆組成物以及其製造方法和用途 |
| RU2694820C9 (ru) | 2014-12-23 | 2019-08-12 | Мерц Фарма Гмбх Унд Ко. Кгаа | Контейнер, предварительно заполненный ботулиновым токсином |
| WO2017179775A1 (en) * | 2016-04-12 | 2017-10-19 | Hugel Inc. | Microstructure formulation techniques for botulinum toxin |
| IL265109B2 (en) * | 2016-09-13 | 2024-05-01 | Allergan Inc | Stabilized non-protein clostridial toxin compositions |
| EP3541358A1 (en) | 2016-11-21 | 2019-09-25 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
| EP3470054B1 (en) * | 2017-10-11 | 2023-09-20 | Hugel Inc. | Microstructure formulation techniques for botulinum toxin |
| US10792400B2 (en) | 2017-10-12 | 2020-10-06 | Hugel Inc. | Microstructure formulation techniques for botulinum toxin |
| US10525111B2 (en) | 2017-10-12 | 2020-01-07 | Hugel, Inc. | Microstructure formulation techniques for botulinum toxin |
| BR112020012641A2 (pt) | 2017-12-20 | 2020-12-01 | Allergan, Inc. | polipeptídeos de domínio de ligação celular de toxina de botulinum e métodos de uso para rejuvenescimento da pele |
| MX2021002992A (es) * | 2018-09-13 | 2021-11-12 | Allergan Inc | Composiciones de toxina clostridial y acido hialuronico. |
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| ATE68524T1 (de) * | 1985-07-09 | 1991-11-15 | Quadrant Bioresources Ltd | Beschuetzung von proteinen und aehnlichem. |
| DE3603444A1 (de) * | 1986-02-05 | 1987-08-06 | Thomae Gmbh Dr K | Pharmazeutische zubereitungsformen zur stabilisierung von interferon alpha |
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| US5945098A (en) * | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
| WO1994000481A1 (en) | 1992-06-23 | 1994-01-06 | Associated Synapse Biologics | Pharmaceutical composition containing botulinum b complex |
| US5756468A (en) | 1994-10-13 | 1998-05-26 | Wisconsin Alumni Research Foundation | Pharmaceutical compositions of botulinum toxin or botulinum neurotoxin and methods of preparation |
| US5512547A (en) | 1994-10-13 | 1996-04-30 | Wisconsin Alumni Research Foundation | Pharmaceutical composition of botulinum neurotoxin and method of preparation |
| US5556771A (en) * | 1995-02-10 | 1996-09-17 | Gen-Probe Incorporated | Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification |
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| TW518235B (en) * | 1997-01-15 | 2003-01-21 | Akzo Nobel Nv | A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage |
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| AU2340299A (en) * | 1998-01-26 | 1999-08-09 | University Of Massachusetts | Biologically active hemagglutinin from type a (clostridium botulinum) and methods of use |
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| BRPI0311959B8 (pt) * | 2002-06-21 | 2021-05-25 | Novo Nordisk Healthcare Ag | composição, métodos para preparar um polipeptídeo estável do fator vii, e para tratar uma síndrome responsiva do fator vii, e, uso do polipeptídeo do fator vii |
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| KR100852824B1 (ko) * | 2004-07-26 | 2008-08-18 | 메르츠 파마 게엠베하 운트 코. 카가아 | 보툴리눔 신경독소를 포함하는 치료 조성물 |
| ES2526912T3 (es) * | 2004-08-04 | 2015-01-16 | Ipsen Biopharm Limited | Composición farmacéutica que contiene neurotoxina botulínica A2 |
| DK1797109T3 (en) * | 2004-09-09 | 2016-04-11 | Yeda Res & Dev | MIXTURES OF POLYPEPTIDES, compositions containing them and methods for their preparation, and uses thereof |
| CA2598204C (en) * | 2004-11-09 | 2015-01-13 | Board Of Regents, The University Of Texas System | Stabilized hme composition with small drug particles |
| ATE523207T1 (de) * | 2005-09-16 | 2011-09-15 | Merial Ltd | Stabilisatoren für gefriergetrocknete impfstoffe |
| US8168206B1 (en) * | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
| US8137677B2 (en) | 2005-10-06 | 2012-03-20 | Allergan, Inc. | Non-protein stabilized clostridial toxin pharmaceutical compositions |
| EP2829282B1 (en) * | 2007-03-22 | 2017-10-25 | The Regents of The University of Colorado, A Body Corporate | Method of preparing an immunologically-active adjuvant-bound dried vaccine composition |
| EP1985276A1 (en) * | 2007-04-26 | 2008-10-29 | Merz Pharma GmbH & Co. KGaA | Treatment of movement disorders by a combined use of a chemodenervating agent and automated movement therapy |
| WO2010037402A1 (en) * | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| EP2248518B1 (en) * | 2009-04-17 | 2013-01-16 | Merz Pharma GmbH & Co. KGaA | Formulation for stabilizing proteins, peptides or mixtures thereof. |
| EP2525777B1 (en) * | 2010-01-20 | 2019-05-29 | UroGen Pharma Ltd. | Material and method for treating internal cavities |
| AU2011316111B2 (en) * | 2010-10-12 | 2015-05-28 | Merz Pharma Gmbh & Co. Kgaa | Formulation suitable for stabilizing proteins, which is free of mammalian excipients |
-
2006
- 2006-09-21 US US11/524,683 patent/US8137677B2/en active Active
- 2006-10-04 AU AU2006299366A patent/AU2006299366B2/en not_active Ceased
- 2006-10-04 KR KR1020077028607A patent/KR101314952B1/ko not_active Expired - Fee Related
- 2006-10-04 DK DK13178507.3T patent/DK2679217T3/en active
- 2006-10-04 WO PCT/US2006/038913 patent/WO2007041664A1/en not_active Ceased
- 2006-10-04 SI SI200632070A patent/SI2679217T1/sl unknown
- 2006-10-04 PL PL13178507.3T patent/PL2679217T3/pl unknown
- 2006-10-04 MX MX2007012062A patent/MX2007012062A/es active IP Right Grant
- 2006-10-04 PT PT131785073T patent/PT2679217T/pt unknown
- 2006-10-04 JP JP2008534672A patent/JP5140595B2/ja not_active Expired - Fee Related
- 2006-10-04 HU HUE13178507A patent/HUE027810T2/en unknown
- 2006-10-04 EP EP13178507.3A patent/EP2679217B1/en not_active Revoked
- 2006-10-04 ES ES13178507.3T patent/ES2580010T3/es active Active
- 2006-10-04 CA CA2602926A patent/CA2602926C/en active Active
- 2006-10-04 EP EP06816283.3A patent/EP1931306B2/en not_active Ceased
- 2006-10-04 NZ NZ562033A patent/NZ562033A/en not_active IP Right Cessation
-
2012
- 2012-02-09 US US13/369,632 patent/US8642047B2/en active Active
- 2012-07-23 JP JP2012162277A patent/JP5758856B2/ja not_active Expired - Fee Related
-
2013
- 2013-12-23 US US14/139,519 patent/US20140112908A1/en not_active Abandoned
-
2014
- 2014-04-01 JP JP2014075596A patent/JP2014139229A/ja active Pending
-
2016
- 2016-06-29 CY CY20161100594T patent/CY1117727T1/el unknown
-
2017
- 2017-01-24 JP JP2017010322A patent/JP6235176B2/ja not_active Expired - Fee Related
-
2020
- 2020-07-01 US US16/918,769 patent/US20200330564A1/en not_active Abandoned
-
2023
- 2023-08-18 US US18/235,530 patent/US20240226252A1/en not_active Abandoned
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