JP2014039864A - 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 - Google Patents
患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 Download PDFInfo
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- JP2014039864A JP2014039864A JP2013219765A JP2013219765A JP2014039864A JP 2014039864 A JP2014039864 A JP 2014039864A JP 2013219765 A JP2013219765 A JP 2013219765A JP 2013219765 A JP2013219765 A JP 2013219765A JP 2014039864 A JP2014039864 A JP 2014039864A
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- 208000001797 obstructive sleep apnea Diseases 0.000 title claims abstract description 21
- 210000000214 mouth Anatomy 0.000 claims description 37
- 230000006837 decompression Effects 0.000 claims description 18
- 238000000034 method Methods 0.000 abstract description 16
- 201000002859 sleep apnea Diseases 0.000 description 10
- 238000010586 diagram Methods 0.000 description 7
- 230000000241 respiratory effect Effects 0.000 description 7
- 210000003928 nasal cavity Anatomy 0.000 description 6
- 210000004872 soft tissue Anatomy 0.000 description 5
- 210000003254 palate Anatomy 0.000 description 4
- 206010020772 Hypertension Diseases 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 208000010125 myocardial infarction Diseases 0.000 description 3
- 230000029058 respiratory gaseous exchange Effects 0.000 description 3
- 210000001584 soft palate Anatomy 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 206010039203 Road traffic accident Diseases 0.000 description 2
- 208000006011 Stroke Diseases 0.000 description 2
- 206010063968 Upper airway resistance syndrome Diseases 0.000 description 2
- 208000008784 apnea Diseases 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 206010041235 Snoring Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000010352 nasal breathing Effects 0.000 description 1
- 210000002741 palatine tonsil Anatomy 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000002396 uvula Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/56—Devices for preventing snoring
- A61F5/566—Intra-oral devices
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- Health & Medical Sciences (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Nursing (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
【解決手段】口腔内陰圧を患者に用いることにより閉塞性睡眠時無呼吸を治療するための装置(3)であって、減圧ユニット(30)と、前記減圧ユニット(30)にその一端が連結されたチューブ(32)と、前記チューブの他端に連結されたマウスピース(34)と、前記患者の舌を保持する舌保持部分(40)とを備える。
【選択図】図3D
Description
の危険性が過剰であり、すなわち、呼吸障害指数(Respiration Disorder Index)(RDI)=5の患者は、睡眠時無呼吸を生じない人と比較して、高血圧のオッズ比が2:1であり、また、RDI=25の患者は、睡眠時無呼吸を生じない人と比較して、高血圧のオッズ比が5:1である。また、心筋梗塞(MI)を生じる危険性が過剰であり、睡眠時無呼吸を患う患者は、再発性心筋梗塞の危険度が23倍増大する。また、卒中の危険性が過剰であり、睡眠時無呼吸を患う患者は、睡眠時無呼吸を生じない人と比較して、卒中のオッズ比が3:2にもなる。また、交通事故の危険性があり、睡眠時無呼吸を治療していない患者は、睡眠時無呼吸を生じない人と比較して交通事故が7倍多く、この未治療患者の交通事故は、走行距離に関して補正したならば12倍多い。
療するための高い有効性、及び、患者への高コンプライアンス性をもたらす。本発明の装置の商業的可能性は非常に大きい
を、上気道の開放性をさらに高めるように保持する。第3実施形態の装置のその他の部分は第1実施形態と同一である。或いは、歯と係合する部分38と弁36とを共に第3実施形態に用いることもできる(図示せず)。
図3Fは、本発明の第5の実施形態に従う装置の概略図である。第5の実施形態においては、鼻腔内の陽圧と口腔内の陰圧とが、上気道の開放性を維持するために組み合わされている。持続的気道内陽圧(CPAP)装置(図示せず)に接続された鼻チューブ42がチューブ32に関連付けられている。鼻チューブ42とチューブ32とは一体的に形成されることができる。陽圧エアが鼻腔内に、持続的気道内陽圧装置により、鼻腔チューブ42を通して供給される。第5の実施形態においては、鼻腔内の陽圧と口腔内の陰圧とが、持続的気道内陽圧装置が高空気圧及び高空気流を鼻腔内に供給する必要がないように組み合わされる。上気道内の高空気圧及び高空気流により生じる不快感が排除され、この装置への患者のコンプライアンスが高められる。すなわち、この装置及びこの方法は、閉塞性睡眠時無呼吸を治療するための伝統的な持続的気道内陽圧装置に必要である圧力設定を減らすことができる。それゆえ、この装置及びこの方法は、高圧及び高空気流により生じる不快感を減じることができる。
Claims (3)
- 口腔内陰圧を患者に用いることにより閉塞性睡眠時無呼吸を治療するための装置(3)であって、
前記患者の口腔の陰圧を制御及び維持するための減圧ユニット(30)と、
口腔内に陰圧を発生させるために口腔内の空気を吸い出すために前記減圧ユニット(30)にその一端が連結されたチューブ(32)であって、前記チューブ(32)は、前記口腔内の空気を吸い出すことによって、前記口腔内に陰圧を発生させることと、
前記チューブの他端に連結されたマウスピース(34)であって、前記マウスピース(34)は、前記患者の口に嵌り込み、且つ前記患者の口を封止することによって、前記口腔が空気を漏らすことを防止することと、
前記患者の舌を保持する舌保持部分(40)であって、前記舌保持部分(40)は、前記舌(311)の位置を保持するように、前記チューブ(32)に対して反対側の前記マウスピース(34)の一端に固定されることと
を備える、装置。 - 前記舌保持部分(40)は、減圧力、磁気力、またはバネ荷重力を用いることによって、前記舌(311)の位置を保持する、
請求項1記載の装置。 - 前記装置(3)はさらに、前記患者の歯と係合する係合部分(38)を備え、
前記係合部分(38)は、前記マウスピース(34)と協働して、前記患者の下顎位置を保持する、
請求項1記載の装置。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80902706P | 2006-05-30 | 2006-05-30 | |
US60/809,027 | 2006-05-30 | ||
US11/727,696 US7918222B2 (en) | 2006-05-30 | 2007-03-28 | Method and apparatus for treating obstructive sleep apnea by using negative oral pressure to a patient |
US11/727,696 | 2007-03-28 |
Related Parent Applications (1)
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JP2012117723A Division JP5399534B2 (ja) | 2006-05-30 | 2012-05-23 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 |
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JP2015076256A Division JP6002798B2 (ja) | 2006-05-30 | 2015-04-02 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 |
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JP2014039864A true JP2014039864A (ja) | 2014-03-06 |
JP5727574B2 JP5727574B2 (ja) | 2015-06-03 |
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Family Applications (4)
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JP2007141778A Pending JP2007319680A (ja) | 2006-05-30 | 2007-05-29 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための方法と装置 |
JP2012117723A Active JP5399534B2 (ja) | 2006-05-30 | 2012-05-23 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 |
JP2013219765A Active JP5727574B2 (ja) | 2006-05-30 | 2013-10-23 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 |
JP2015076256A Active JP6002798B2 (ja) | 2006-05-30 | 2015-04-02 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 |
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JP2007141778A Pending JP2007319680A (ja) | 2006-05-30 | 2007-05-29 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための方法と装置 |
JP2012117723A Active JP5399534B2 (ja) | 2006-05-30 | 2012-05-23 | 患者に口腔内陰圧を用いることにより閉塞性睡眠時無呼吸を治療するための装置 |
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Country Status (6)
Country | Link |
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US (1) | US7918222B2 (ja) |
EP (1) | EP1862152B1 (ja) |
JP (4) | JP2007319680A (ja) |
AT (1) | ATE497378T1 (ja) |
DE (1) | DE602007012323D1 (ja) |
TW (1) | TWI353831B (ja) |
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- 2007-05-24 EP EP07108890A patent/EP1862152B1/en active Active
- 2007-05-24 AT AT07108890T patent/ATE497378T1/de not_active IP Right Cessation
- 2007-05-24 DE DE602007012323T patent/DE602007012323D1/de active Active
- 2007-05-29 JP JP2007141778A patent/JP2007319680A/ja active Pending
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Also Published As
Publication number | Publication date |
---|---|
US7918222B2 (en) | 2011-04-05 |
JP5399534B2 (ja) | 2014-01-29 |
TW200744551A (en) | 2007-12-16 |
EP1862152A1 (en) | 2007-12-05 |
TWI353831B (en) | 2011-12-11 |
US20070277818A1 (en) | 2007-12-06 |
EP1862152B1 (en) | 2011-02-02 |
JP2015126926A (ja) | 2015-07-09 |
JP2012179404A (ja) | 2012-09-20 |
JP5727574B2 (ja) | 2015-06-03 |
JP2007319680A (ja) | 2007-12-13 |
JP6002798B2 (ja) | 2016-10-05 |
ATE497378T1 (de) | 2011-02-15 |
DE602007012323D1 (de) | 2011-03-17 |
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