JP2013544838A - 網膜の疾患を治療するための方法 - Google Patents

網膜の疾患を治療するための方法 Download PDF

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Publication number
JP2013544838A
JP2013544838A JP2013542043A JP2013542043A JP2013544838A JP 2013544838 A JP2013544838 A JP 2013544838A JP 2013542043 A JP2013542043 A JP 2013542043A JP 2013542043 A JP2013542043 A JP 2013542043A JP 2013544838 A JP2013544838 A JP 2013544838A
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JP
Japan
Prior art keywords
retinal
retinal pigment
compound
blue light
eye
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Pending
Application number
JP2013542043A
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English (en)
Japanese (ja)
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JP2013544838A5 (https=
Inventor
ジョティルモイ エックス クサリ
シーラ エックス チョウ
ミンティン ティエン
エドウィン ユー パディロ
サンディア エス ラオ
ダニエル ダブリュ ジル
ラリー エイ ウィーラー
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Allergan Inc
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Allergan Inc
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Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of JP2013544838A publication Critical patent/JP2013544838A/ja
Publication of JP2013544838A5 publication Critical patent/JP2013544838A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2013542043A 2010-12-03 2011-11-18 網膜の疾患を治療するための方法 Pending JP2013544838A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41966010P 2010-12-03 2010-12-03
US61/419,660 2010-12-03
PCT/US2011/061370 WO2012074788A1 (en) 2010-12-03 2011-11-18 Methods for treating diseases of the retina

Publications (2)

Publication Number Publication Date
JP2013544838A true JP2013544838A (ja) 2013-12-19
JP2013544838A5 JP2013544838A5 (https=) 2015-01-15

Family

ID=45507856

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013542043A Pending JP2013544838A (ja) 2010-12-03 2011-11-18 網膜の疾患を治療するための方法

Country Status (10)

Country Link
US (2) US9018202B2 (https=)
EP (1) EP2646034A1 (https=)
JP (1) JP2013544838A (https=)
KR (1) KR20130122958A (https=)
CN (1) CN103327981A (https=)
AU (1) AU2011336976A1 (https=)
BR (1) BR112013013636A2 (https=)
CA (1) CA2819616A1 (https=)
RU (1) RU2013129748A (https=)
WO (1) WO2012074788A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022163086A (ja) * 2017-07-06 2022-10-25 健一 山田 脂質過酸化誘発性疾患の治療薬およびそのスクリーニング方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10752593B2 (en) 2018-12-28 2020-08-25 Endogena Therapeutics, Inc. Compounds for use as therapeutically active substances in the treatment of retinal diseases
US10807973B2 (en) 2018-12-28 2020-10-20 Endogena Therapeutics, Inc. Compounds for use as therapeutically active substances in the treatment of retinal diseases
EP3919052A4 (en) * 2019-01-09 2022-10-05 Fuso Pharmaceutical Industries, Ltd. Pharmaceutical composition for intraocular or oral administration for treatment of retinal diseases
US20250170143A1 (en) * 2022-04-14 2025-05-29 Mayo Foundation For Medical Education And Research Methods of treating ocular fibrotic pathologies

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10175865A (ja) * 1996-12-11 1998-06-30 Towa Rin 抗眼圧活性製剤
WO2004103263A2 (en) * 2003-05-22 2004-12-02 Yeda Research And Development Co. Ltd. Dopamine and agonists and antagonists thereof for treatment of neurodegenerative diseases
JP2006515628A (ja) * 2003-01-23 2006-06-01 アカディア ファーマシューティカルズ,インコーポレーテッド ヒト神経精神疾患を処置するためのn−デスメチルクロザピンの使用
JP2008509147A (ja) * 2004-08-05 2008-03-27 アカディア ファーマシューティカルズ,インコーポレーテッド ヒト神経精神病を治療するためのn−デスメチルクロザピンの使用
WO2008111497A1 (ja) * 2007-03-08 2008-09-18 Santen Pharmaceutical Co., Ltd. トリテルペノイドを有効成分として含有する酸化ストレスが関連する眼疾患の予防又は治療剤
JP2010523651A (ja) * 2007-04-12 2010-07-15 エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ 改善された心血管副作用プロフィールを呈する、ドーパミン受容体安定剤/調節剤のn−オキシド誘導体及び/又はジ−n−オキシド誘導体

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1004520A1 (en) 1992-05-13 1998-11-27 Novartis Ag Ophthalmic compositions containing a cyclosporin
US5474979A (en) 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
US5631250A (en) 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
US5744468A (en) * 1996-10-23 1998-04-28 Tong-Ho Lin Hypotensive intraocular pressure activity of clozapine and sulpiride
US7160898B2 (en) * 2001-12-14 2007-01-09 Board Of Trustees Of The University Of Illinois Pharmacological treatment for sleep apnea
JP2002530340A (ja) * 1998-11-23 2002-09-17 セプラコール, インク. オランザピン−n−オキサイドを含む医薬組成物
DE10206941A1 (de) 2002-02-19 2003-09-25 Goetz Nowak Neue Arzneimittel
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US20050277584A1 (en) 2004-06-09 2005-12-15 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US20060035887A1 (en) 2004-07-02 2006-02-16 Dr. Reddy's Laboratories Limited Process for preparing olanzapine
CN101437478A (zh) * 2004-10-04 2009-05-20 Qlt美国有限公司 聚合送递制剂的眼部送递
MX2007003789A (es) 2004-10-04 2007-07-20 Qlt Usa Inc Suministro ocular de formulaciones polimericas para suministro.
US7297679B2 (en) 2005-07-13 2007-11-20 Allergan, Inc. Cyclosporin compositions
US20070015691A1 (en) 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10175865A (ja) * 1996-12-11 1998-06-30 Towa Rin 抗眼圧活性製剤
JP2006515628A (ja) * 2003-01-23 2006-06-01 アカディア ファーマシューティカルズ,インコーポレーテッド ヒト神経精神疾患を処置するためのn−デスメチルクロザピンの使用
WO2004103263A2 (en) * 2003-05-22 2004-12-02 Yeda Research And Development Co. Ltd. Dopamine and agonists and antagonists thereof for treatment of neurodegenerative diseases
JP2008509147A (ja) * 2004-08-05 2008-03-27 アカディア ファーマシューティカルズ,インコーポレーテッド ヒト神経精神病を治療するためのn−デスメチルクロザピンの使用
WO2008111497A1 (ja) * 2007-03-08 2008-09-18 Santen Pharmaceutical Co., Ltd. トリテルペノイドを有効成分として含有する酸化ストレスが関連する眼疾患の予防又は治療剤
JP2010523651A (ja) * 2007-04-12 2010-07-15 エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ 改善された心血管副作用プロフィールを呈する、ドーパミン受容体安定剤/調節剤のn−オキシド誘導体及び/又はジ−n−オキシド誘導体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
メルクマニュアル 第18版 日本語版, vol. 第3刷, JPN6015042705, 25 April 2007 (2007-04-25), pages 944頁, ISSN: 0003181754 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022163086A (ja) * 2017-07-06 2022-10-25 健一 山田 脂質過酸化誘発性疾患の治療薬およびそのスクリーニング方法
US12306164B2 (en) 2017-07-06 2025-05-20 Ken-Ichi Yamamada Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases

Also Published As

Publication number Publication date
CN103327981A (zh) 2013-09-25
US9018202B2 (en) 2015-04-28
CA2819616A1 (en) 2012-06-07
AU2011336976A1 (en) 2013-07-11
US9561234B2 (en) 2017-02-07
BR112013013636A2 (pt) 2016-11-08
EP2646034A1 (en) 2013-10-09
RU2013129748A (ru) 2015-01-10
WO2012074788A1 (en) 2012-06-07
KR20130122958A (ko) 2013-11-11
US20150290215A1 (en) 2015-10-15
US20120142675A1 (en) 2012-06-07

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