JP2013542927A5 - - Google Patents
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- Publication number
- JP2013542927A5 JP2013542927A5 JP2013529730A JP2013529730A JP2013542927A5 JP 2013542927 A5 JP2013542927 A5 JP 2013542927A5 JP 2013529730 A JP2013529730 A JP 2013529730A JP 2013529730 A JP2013529730 A JP 2013529730A JP 2013542927 A5 JP2013542927 A5 JP 2013542927A5
- Authority
- JP
- Japan
- Prior art keywords
- fatty acid
- aqueous phase
- oil mixture
- concentrate
- silver salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 42
- 235000014113 dietary fatty acids Nutrition 0.000 claims 35
- 229930195729 fatty acid Natural products 0.000 claims 35
- 239000000194 fatty acid Substances 0.000 claims 35
- 150000004665 fatty acids Chemical class 0.000 claims 35
- 239000008346 aqueous phase Substances 0.000 claims 17
- 239000003921 oil Substances 0.000 claims 17
- 235000019198 oils Nutrition 0.000 claims 17
- 239000012141 concentrate Substances 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 15
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 10
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 10
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 claims 9
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 6
- 238000000605 extraction Methods 0.000 claims 5
- 239000000243 solution Substances 0.000 claims 5
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 claims 4
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 4
- 238000005194 fractionation Methods 0.000 claims 4
- 239000007788 liquid Substances 0.000 claims 4
- 235000020665 omega-6 fatty acid Nutrition 0.000 claims 4
- 229940033080 omega-6 fatty acid Drugs 0.000 claims 4
- 239000012266 salt solution Substances 0.000 claims 3
- 239000007864 aqueous solution Substances 0.000 claims 2
- 235000012000 cholesterol Nutrition 0.000 claims 2
- 239000000356 contaminant Substances 0.000 claims 2
- 238000005657 iodolactonization reaction Methods 0.000 claims 2
- 239000006014 omega-3 oil Substances 0.000 claims 2
- 239000012074 organic phase Substances 0.000 claims 2
- 230000002085 persistent effect Effects 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 2
- 101710134784 Agnoprotein Proteins 0.000 claims 1
- 241001474374 Blennius Species 0.000 claims 1
- YVGGHNCTFXOJCH-UHFFFAOYSA-N DDT Chemical compound C1=CC(Cl)=CC=C1C(C(Cl)(Cl)Cl)C1=CC=C(Cl)C=C1 YVGGHNCTFXOJCH-UHFFFAOYSA-N 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 1
- 239000010775 animal oil Substances 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 150000002013 dioxins Chemical class 0.000 claims 1
- 238000004821 distillation Methods 0.000 claims 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 1
- 239000003344 environmental pollutant Substances 0.000 claims 1
- 125000004494 ethyl ester group Chemical group 0.000 claims 1
- 125000005456 glyceride group Chemical group 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
- 238000000199 molecular distillation Methods 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 150000003071 polychlorinated biphenyls Chemical class 0.000 claims 1
- 238000004237 preparative chromatography Methods 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 238000000526 short-path distillation Methods 0.000 claims 1
- 238000000194 supercritical-fluid extraction Methods 0.000 claims 1
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 1
- 239000008158 vegetable oil Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38609610P | 2010-09-24 | 2010-09-24 | |
| US61/386,096 | 2010-09-24 | ||
| PCT/IB2011/002593 WO2012038833A1 (en) | 2010-09-24 | 2011-09-23 | Process for concentrating omega-3 fatty acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013542927A JP2013542927A (ja) | 2013-11-28 |
| JP2013542927A5 true JP2013542927A5 (https=) | 2014-11-13 |
| JP5946833B2 JP5946833B2 (ja) | 2016-07-06 |
Family
ID=45873506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013529730A Active JP5946833B2 (ja) | 2010-09-24 | 2011-09-23 | ω３脂肪酸を濃縮する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9145533B2 (https=) |
| EP (1) | EP2619298B1 (https=) |
| JP (1) | JP5946833B2 (https=) |
| KR (1) | KR101904392B1 (https=) |
| CN (1) | CN103221524B (https=) |
| AU (1) | AU2011306471B2 (https=) |
| CA (1) | CA2812305C (https=) |
| CL (1) | CL2013000792A1 (https=) |
| ES (1) | ES2700134T3 (https=) |
| PE (1) | PE20140202A1 (https=) |
| SG (1) | SG188626A1 (https=) |
| WO (1) | WO2012038833A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012118173A1 (ja) † | 2011-03-03 | 2012-09-07 | 日本水産株式会社 | リパーゼによる高度不飽和脂肪酸含有油脂の製造方法 |
| RS57777B1 (sr) | 2012-01-06 | 2018-12-31 | Omthera Pharmaceuticals Inc | Dpa-obogaćene kompozicije omega-3 polinezasićenih masnih kiselina u obliku slobodne kiseline |
| EP2846779A4 (en) | 2012-05-07 | 2015-12-16 | Omthera Pharmaceuticals Inc | STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS |
| KR20240096704A (ko) | 2012-05-14 | 2024-06-26 | 가부시키가이샤 닛스이 | 환경 오염 물질을 저감시킨 고도 불포화 지방산 또는 고도 불포화 지방산 에틸에스테르 및 그 제조 방법 |
| KR20150098611A (ko) * | 2012-10-23 | 2015-08-28 | 디킨 유니버시티 | 트리글리세라이드를 감소시키기 위한 방법 |
| JP6234908B2 (ja) * | 2013-09-30 | 2017-11-22 | 日清ファルマ株式会社 | エイコサペンタエン酸及び／又はドコサヘキサエン酸含有組成物の製造方法 |
| EP3066183A4 (en) * | 2013-11-08 | 2017-09-27 | Omega Protein Corporation | Purification of dpa enriched oil |
| TWI725937B (zh) * | 2014-06-06 | 2021-05-01 | 美商海洋原料公司 | ω-３組成物、劑型及使用方法 |
| CN107666904B (zh) * | 2015-03-26 | 2022-02-01 | 提贝托·布鲁泽塞 | 多不饱和脂肪酸的纯化组合物、其制备方法及其用途 |
| CN108024984A (zh) | 2015-06-26 | 2018-05-11 | 普罗诺瓦生物医药挪威公司 | 用于治疗nafld的组合物 |
| CN109072126B (zh) * | 2016-05-02 | 2022-03-22 | 日清药业股份有限公司 | 含有高度不饱和脂肪酸的组合物的制造方法 |
| CN107162910B (zh) * | 2017-05-19 | 2019-12-31 | 陕西源邦生物技术有限公司 | 从鱼油中制备高纯度epa-ee的方法 |
| US10899994B2 (en) | 2017-06-14 | 2021-01-26 | Nisshin Pharma Inc. | Method for producing polyunsaturated fatty acid-containing composition |
| EP3586642A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Ala enriched polyunsaturated fatty acid compositions |
| EP3586643A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
| EP3586640A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
| EP3586641A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
| JP7528054B2 (ja) * | 2019-03-26 | 2024-08-05 | 日清ファルマ株式会社 | エイコサペンタエン酸アルキルエステル含有組成物の製造方法 |
| CN111085006A (zh) * | 2019-12-24 | 2020-05-01 | 河北省地矿局第二地质大队 | 一种环境中有机污染物提取工艺 |
| TWI751577B (zh) * | 2020-06-05 | 2022-01-01 | 中化合成生技股份有限公司 | 利用連續式反應器以純化多不飽和脂肪酸之方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2839276B2 (ja) * | 1989-01-23 | 1998-12-16 | 日本分光工業株式会社 | 超臨界流体抽出・分離方法及び装置 |
| JPH06248289A (ja) * | 1993-02-27 | 1994-09-06 | Nippon Suisan Kaisha Ltd | 高度不飽和脂肪酸類を選択的に分離回収する方法 |
| JPH07242895A (ja) * | 1993-03-16 | 1995-09-19 | Ikeda Shiyotsuken Kk | 高純度エイコサペンタエン酸又はその低級アルコールエステルの分離精製法 |
| JP2001240893A (ja) * | 1999-12-20 | 2001-09-04 | Q P Corp | エイコサペンタエン酸又はその誘導体の精製方法 |
| JP2001335794A (ja) * | 2000-05-29 | 2001-12-04 | Q P Corp | ドコサヘキサエン酸又はその誘導体の精製方法 |
| CN1223664C (zh) * | 2003-07-21 | 2005-10-19 | 天津市医药科学研究所 | 从鱼油中提纯高含量dha、epa的方法 |
| JP5503856B2 (ja) * | 2008-09-10 | 2014-05-28 | キユーピー株式会社 | 高度不飽和脂肪酸誘導体の取得方法 |
| US8173826B2 (en) * | 2009-06-17 | 2012-05-08 | Chevron U.S.A. Inc. | Enrichment of monounsaturated acids/esters in vegetable oil—or animal fat-based feedstock using metal salts dissolved in ionic liquids |
-
2011
- 2011-09-23 US US13/825,739 patent/US9145533B2/en active Active
- 2011-09-23 SG SG2013021076A patent/SG188626A1/en unknown
- 2011-09-23 CN CN201180055920.8A patent/CN103221524B/zh active Active
- 2011-09-23 JP JP2013529730A patent/JP5946833B2/ja active Active
- 2011-09-23 PE PE2013000638A patent/PE20140202A1/es active IP Right Grant
- 2011-09-23 CA CA2812305A patent/CA2812305C/en not_active Expired - Fee Related
- 2011-09-23 KR KR1020137010139A patent/KR101904392B1/ko active Active
- 2011-09-23 EP EP11826479.5A patent/EP2619298B1/en active Active
- 2011-09-23 AU AU2011306471A patent/AU2011306471B2/en not_active Ceased
- 2011-09-23 WO PCT/IB2011/002593 patent/WO2012038833A1/en not_active Ceased
- 2011-09-23 ES ES11826479T patent/ES2700134T3/es active Active
-
2013
- 2013-03-22 CL CL2013000792A patent/CL2013000792A1/es unknown
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