JP2013542185A5 - - Google Patents
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- Publication number
- JP2013542185A5 JP2013542185A5 JP2013528356A JP2013528356A JP2013542185A5 JP 2013542185 A5 JP2013542185 A5 JP 2013542185A5 JP 2013528356 A JP2013528356 A JP 2013528356A JP 2013528356 A JP2013528356 A JP 2013528356A JP 2013542185 A5 JP2013542185 A5 JP 2013542185A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- polypeptide
- transcription
- factor
- high mobility
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38137710P | 2010-09-09 | 2010-09-09 | |
| US61/381,377 | 2010-09-09 | ||
| PCT/US2011/051107 WO2012034090A1 (en) | 2010-09-09 | 2011-09-09 | Compositions and methods for the removal of biofilms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015193476A Division JP2016000760A (ja) | 2010-09-09 | 2015-09-30 | バイオフィルムを除去するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013542185A JP2013542185A (ja) | 2013-11-21 |
| JP2013542185A5 true JP2013542185A5 (enExample) | 2014-09-25 |
| JP6012603B2 JP6012603B2 (ja) | 2016-10-25 |
Family
ID=44654515
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013528356A Active JP6012603B2 (ja) | 2010-09-09 | 2011-09-09 | バイオフィルムを除去するための組成物および方法 |
| JP2015193476A Withdrawn JP2016000760A (ja) | 2010-09-09 | 2015-09-30 | バイオフィルムを除去するための組成物および方法 |
| JP2017122250A Active JP6420417B2 (ja) | 2010-09-09 | 2017-06-22 | バイオフィルムを除去するための組成物および方法 |
| JP2018081136A Withdrawn JP2018111731A (ja) | 2010-09-09 | 2018-04-20 | バイオフィルムを除去するための組成物および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015193476A Withdrawn JP2016000760A (ja) | 2010-09-09 | 2015-09-30 | バイオフィルムを除去するための組成物および方法 |
| JP2017122250A Active JP6420417B2 (ja) | 2010-09-09 | 2017-06-22 | バイオフィルムを除去するための組成物および方法 |
| JP2018081136A Withdrawn JP2018111731A (ja) | 2010-09-09 | 2018-04-20 | バイオフィルムを除去するための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20120128701A1 (enExample) |
| EP (1) | EP2613797B1 (enExample) |
| JP (4) | JP6012603B2 (enExample) |
| AU (1) | AU2011299025B2 (enExample) |
| CA (1) | CA2810851C (enExample) |
| WO (1) | WO2012034090A1 (enExample) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9585920B2 (en) | 2011-02-04 | 2017-03-07 | Katherine Rose Kovarik | Method and system for treating cancer cachexia |
| US9457077B2 (en) | 2009-11-18 | 2016-10-04 | Katherine Rose Kovarik | Method and system for targeting the microbiome to promote health and treat allergic and inflammatory diseases |
| SG183816A1 (en) * | 2010-03-29 | 2012-10-30 | Res Inst Nationwide Childrens Hospital | Compositions and methods for the removal of biofilms |
| EP2613797B1 (en) | 2010-09-09 | 2015-11-04 | University Of Southern California | Compositions and methods for the removal of biofilms |
| US10314865B2 (en) | 2011-02-04 | 2019-06-11 | Katherine Rose Kovarik | Method and system for treating cancer and other age-related diseases by extending the healthspan of a human |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US9730967B2 (en) | 2011-02-04 | 2017-08-15 | Katherine Rose Kovarik | Method and system for treating cancer cachexia |
| US12533312B2 (en) | 2011-02-04 | 2026-01-27 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
| US10940169B2 (en) | 2015-11-30 | 2021-03-09 | Joseph E. Kovarik | Method for reducing the likelihood of developing cancer in an individual human being |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
| US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| AU2014278037A1 (en) * | 2013-06-13 | 2016-01-07 | Ohio State Innovation Foundation | Compositions and methods for the treatment of Burkholderia infections |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US9745366B2 (en) | 2013-09-23 | 2017-08-29 | University Of Southern California | Compositions and methods for the prevention of microbial infections |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US10233234B2 (en) | 2014-01-13 | 2019-03-19 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US11672835B2 (en) | 2013-12-20 | 2023-06-13 | Seed Health, Inc. | Method for treating individuals having cancer and who are receiving cancer immunotherapy |
| US11026982B2 (en) | 2015-11-30 | 2021-06-08 | Joseph E. Kovarik | Method for reducing the likelihood of developing bladder or colorectal cancer in an individual human being |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US11213552B2 (en) | 2015-11-30 | 2022-01-04 | Joseph E. Kovarik | Method for treating an individual suffering from a chronic infectious disease and cancer |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| US11529379B2 (en) | 2013-12-20 | 2022-12-20 | Seed Health, Inc. | Method and system for reducing the likelihood of developing colorectal cancer in an individual human being |
| US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
| US11642382B2 (en) | 2013-12-20 | 2023-05-09 | Seed Health, Inc. | Method for treating an individual suffering from bladder cancer |
| US10624934B2 (en) | 2014-03-06 | 2020-04-21 | Research Institute At Nationwide Children's Hospital | Prebiotic formulations |
| AU2015227075A1 (en) | 2014-03-06 | 2016-09-22 | Ohio State Innovation Foundation | Probiotic formulations and methods for use |
| WO2016154491A1 (en) * | 2015-03-25 | 2016-09-29 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| WO2017011588A1 (en) | 2015-07-14 | 2017-01-19 | Research Institute At Nationwide Children's Hospital | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
| CA2993009A1 (en) | 2015-07-31 | 2017-02-09 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| WO2017066719A2 (en) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Hu specific interfering agents |
| CA3049114A1 (en) | 2017-01-04 | 2018-07-12 | Lauren O. Bakaletz | Antibody fragments for the treatment of biofilm-related disorders |
| JP7514621B2 (ja) | 2017-01-04 | 2024-07-11 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | Ｄｎａｂｉｉワクチンおよび強化された活性を有する抗体 |
| PL3556378T3 (pl) | 2017-01-27 | 2025-06-09 | StemRIM Inc. | Środek do leczenia kardiomiopatii, starego zawału mięśnia sercowego i przewlekłej niewydolności serca |
| AU2018236271B2 (en) * | 2017-03-15 | 2023-12-21 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| CN118460462A (zh) | 2017-12-01 | 2024-08-09 | 斯特姆里姆有限公司 | 外胚层间充质干细胞及其产生方法 |
| US11298403B2 (en) | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
| WO2019156137A1 (ja) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | 乾癬の治療薬 |
| JP7235776B2 (ja) * | 2018-06-12 | 2023-03-08 | テルモ カーディオバスキュラー システムズ コーポレイション | 心血管弁処置のための円形リトラクタ |
| JP6641420B2 (ja) | 2018-06-12 | 2020-02-05 | 株式会社アマダホールディングス | 分割金型の装着方法及びプレスブレーキ |
| WO2020072993A1 (en) | 2018-10-05 | 2020-04-09 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms cross-reference to related application |
| US12304933B2 (en) | 2018-10-05 | 2025-05-20 | StemRIM Inc. | Disease treatment drug based on mesenchymal-stem-cell mobilization |
| US12569524B2 (en) | 2018-10-22 | 2026-03-10 | Research Institute At Nationwide Children's Hospital | Compositions and methods for preventing and treating antibiotic induced pathologies using probiotics in the biofilm state |
| EP3930735A1 (en) | 2019-02-26 | 2022-01-05 | The Regents of the University of Colorado, a body corporate | Method and composition for treating gastrointestinal inflammatory disorders |
| KR20220016481A (ko) | 2019-06-03 | 2022-02-09 | 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 | 패혈증 및 괴사성 장염 유도된 신경발달 결핍의 예방을 위한 프리바이오틱 제형 |
| JP7627255B2 (ja) | 2019-07-08 | 2025-02-05 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | バイオフィルムを破壊するための抗体組成物 |
| WO2025106896A1 (en) * | 2023-11-17 | 2025-05-22 | Rush University Medical Center | Coating of medical and implant biomaterials with an anti-biofilm agent to prevent and treat infection |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US6355450B1 (en) | 1995-04-21 | 2002-03-12 | Human Genome Sciences, Inc. | Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof |
| US20050131222A1 (en) | 1995-04-21 | 2005-06-16 | Human Genome Sciences, Inc. | Nucleotide sequence of the haemophilus influenzae Rd genome, fragments thereof, and uses thereof |
| US6303321B1 (en) * | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
| US20020132753A1 (en) * | 2000-01-31 | 2002-09-19 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| AU2002367953C1 (en) | 2001-05-04 | 2009-02-19 | Paratek Pharmaceuticals, Inc | Transcription factor modulating compounds and methods of use thereof |
| BR0209689A (pt) * | 2001-05-15 | 2006-02-07 | Long Island Jewish Res Inst | Uso de fragmento de hmg como agente anti-inflamatório |
| JP4511173B2 (ja) | 2001-08-24 | 2010-07-28 | マイジェニックス インコーポレイテッド | 抗菌性および抗炎症性ペプチド |
| ITMI20011986A1 (it) * | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
| US20030099602A1 (en) | 2001-10-25 | 2003-05-29 | Levin Gilbert V. | D-tagatose as an anti-biofilm agent |
| CA2493124C (en) | 2002-08-02 | 2014-04-29 | Glaxosmithkline Biologicals S.A. | Vaccine |
| GB0226251D0 (en) * | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| AU2003295653B2 (en) * | 2002-11-20 | 2007-08-16 | The Feinstein Institute Of Medical Research | Use of HMGB polypeptides for increasing immune responses |
| ATE472556T1 (de) | 2002-12-02 | 2010-07-15 | Amgen Fremont Inc | Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen |
| WO2004061456A2 (de) * | 2003-01-03 | 2004-07-22 | Alcedo Biotech Gmbh | Verwendungen von hmgb, hmgn, hmga proteinen |
| US7297340B2 (en) | 2003-01-07 | 2007-11-20 | University Of Iowa Research Foundation | Vaccine and method for preventing biofilm formation |
| EP1592707A2 (en) * | 2003-02-14 | 2005-11-09 | Fondazione Centro San Raffaele Del Monte Tabor | Hmgb1 modulator binding domain |
| CA2517899A1 (en) | 2003-03-06 | 2004-09-16 | Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| WO2005025604A2 (en) * | 2003-09-10 | 2005-03-24 | The General Hospital Corporation | Use of hmgb and hmgb fragments to decrease specific immune response |
| WO2005093067A1 (ja) | 2004-03-26 | 2005-10-06 | Locomogene, Inc. | シノビオリン遺伝子のプロモーターに対するデコイ核酸 |
| WO2006083301A2 (en) * | 2004-06-17 | 2006-08-10 | Medimmune, Inc. | Immunogenic compositions comprising hmgb1 polypeptides |
| EP1791566A4 (en) | 2004-08-06 | 2008-07-16 | Nat Jewish Med & Res Center | PRODUCT AND METHOD FOR INHIBITING BIOFILM DEVELOPMENT |
| CN101132811B (zh) | 2004-10-22 | 2012-05-30 | 米迪缪尼有限公司 | 抗hmgb1的高亲和力抗体及其用法 |
| US20060228384A1 (en) | 2005-04-06 | 2006-10-12 | Sequoia Sciences, Inc. | Control of biofilm with a biofilm inhibitor |
| WO2006114805A2 (en) * | 2005-04-28 | 2006-11-02 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb2 and hmgb3 proteins for medical applications |
| CA2642264A1 (en) | 2006-02-13 | 2007-08-30 | Trustees Of Boston University | Reca inhibitors with antibiotic activity, compositions and methods of use |
| NZ574758A (en) | 2006-08-21 | 2012-03-30 | Univ British Columbia | Small cationic antimicrobial peptides |
| EP1980269A1 (en) | 2007-04-13 | 2008-10-15 | Katholieke Universiteit Leuven | Prevention of staphylococcus biofilm formation |
| SG183816A1 (en) | 2010-03-29 | 2012-10-30 | Res Inst Nationwide Childrens Hospital | Compositions and methods for the removal of biofilms |
| EP2613797B1 (en) * | 2010-09-09 | 2015-11-04 | University Of Southern California | Compositions and methods for the removal of biofilms |
| AU2014278037A1 (en) | 2013-06-13 | 2016-01-07 | Ohio State Innovation Foundation | Compositions and methods for the treatment of Burkholderia infections |
| US9745366B2 (en) | 2013-09-23 | 2017-08-29 | University Of Southern California | Compositions and methods for the prevention of microbial infections |
-
2011
- 2011-09-09 EP EP11758346.8A patent/EP2613797B1/en active Active
- 2011-09-09 AU AU2011299025A patent/AU2011299025B2/en active Active
- 2011-09-09 JP JP2013528356A patent/JP6012603B2/ja active Active
- 2011-09-09 WO PCT/US2011/051107 patent/WO2012034090A1/en not_active Ceased
- 2011-09-09 CA CA2810851A patent/CA2810851C/en active Active
- 2011-09-09 US US13/229,575 patent/US20120128701A1/en not_active Abandoned
-
2015
- 2015-09-30 JP JP2015193476A patent/JP2016000760A/ja not_active Withdrawn
- 2015-10-16 US US14/885,800 patent/US10595530B2/en active Active
-
2017
- 2017-06-22 JP JP2017122250A patent/JP6420417B2/ja active Active
-
2018
- 2018-04-20 JP JP2018081136A patent/JP2018111731A/ja not_active Withdrawn
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