JP2013541586A5 - - Google Patents
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- Publication number
- JP2013541586A5 JP2013541586A5 JP2013537756A JP2013537756A JP2013541586A5 JP 2013541586 A5 JP2013541586 A5 JP 2013541586A5 JP 2013537756 A JP2013537756 A JP 2013537756A JP 2013537756 A JP2013537756 A JP 2013537756A JP 2013541586 A5 JP2013541586 A5 JP 2013541586A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pyrazin
- yloxy
- pyrazol
- piperidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41113710P | 2010-11-08 | 2010-11-08 | |
| US61/411,137 | 2010-11-08 | ||
| PCT/US2011/058692 WO2012064548A1 (en) | 2010-11-08 | 2011-11-01 | Compounds useful for inhibiting chk1 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013541586A JP2013541586A (ja) | 2013-11-14 |
| JP2013541586A5 true JP2013541586A5 (enExample) | 2014-12-18 |
| JP5792316B2 JP5792316B2 (ja) | 2015-10-07 |
Family
ID=45044707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537756A Active JP5792316B2 (ja) | 2010-11-08 | 2011-11-01 | Ｃｈｋ１を阻害するのに有用な化合物 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9067920B2 (enExample) |
| EP (1) | EP2638033B1 (enExample) |
| JP (1) | JP5792316B2 (enExample) |
| KR (1) | KR101533166B1 (enExample) |
| CN (1) | CN103180311B (enExample) |
| AR (1) | AR083575A1 (enExample) |
| AU (1) | AU2011326230B2 (enExample) |
| BR (1) | BR112013010009B1 (enExample) |
| CA (1) | CA2816944C (enExample) |
| DK (1) | DK2638033T3 (enExample) |
| EA (1) | EA022096B1 (enExample) |
| ES (1) | ES2541414T3 (enExample) |
| HR (1) | HRP20150530T1 (enExample) |
| JO (1) | JO3145B1 (enExample) |
| ME (1) | ME02119B (enExample) |
| MX (1) | MX2013005181A (enExample) |
| PL (1) | PL2638033T3 (enExample) |
| PT (1) | PT2638033E (enExample) |
| RS (1) | RS54012B1 (enExample) |
| SI (1) | SI2638033T1 (enExample) |
| TW (1) | TWI501956B (enExample) |
| WO (1) | WO2012064548A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201402277D0 (en) | 2014-02-10 | 2014-03-26 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| SI3411036T1 (sl) | 2016-02-04 | 2022-03-31 | Pharmaengine, Inc. | 3,5-disubstituirani pirazoli, uporabni kot kontrolne točke inhibitorjev kinaze 1 (CHK1), ter njihovi pripravki in uporaba |
| EP3461480A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer |
| CN112457306A (zh) | 2019-09-06 | 2021-03-09 | 上海瑛派药业有限公司 | 3,5-二取代吡唑化合物作为激酶抑制剂及其应用 |
| US11564920B2 (en) | 2020-11-30 | 2023-01-31 | Sumitomo Pharma Co., Ltd. | 5-heteroaryl-1H-pyrazol-3-amine derivative |
| EP4253377A4 (en) * | 2020-11-30 | 2024-10-16 | Sumitomo Pharma Co., Ltd. | 5-HETEROARYL-1H-PYRAZOL-3-AMINE DERIVATIVE |
| EP4455134A4 (en) | 2021-12-24 | 2025-10-08 | Sumitomo Pharma Co Ltd | 1H-PYRAZOLE-3-AMINE DERIVATIVE HAVING A BICYCLIC SKELETON |
| WO2023229032A1 (ja) * | 2022-05-27 | 2023-11-30 | 住友ファーマ株式会社 | 免疫チェックポイント阻害剤に対して治療抵抗性を示すがんの治療薬 |
| AU2024255916A1 (en) * | 2023-04-14 | 2025-11-13 | Blueprint Medicines Corporation | Cdk2 inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006528661A (ja) * | 2003-07-25 | 2006-12-21 | ファイザー・インク | アミノピラゾール化合物およびｃｈｋ１阻害剤としての使用 |
| AU2004312193B2 (en) * | 2004-01-05 | 2008-09-25 | Astrazeneca Ab | Thiophene derivatives as CHK 1 inihibitors |
| CA2568451A1 (en) * | 2004-06-04 | 2005-12-22 | Arena Pharmaceuticals, Inc. | Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| JP2008540391A (ja) * | 2005-05-05 | 2008-11-20 | アストラゼネカ アクチボラグ | ピラゾリルアミノ置換ピリミジン、および癌の処置におけるそれらの使用 |
| EP1893607A4 (en) * | 2005-06-09 | 2010-07-21 | Merck Sharp & Dohme | CHECKPOINT KINASE INHIBITORS |
| WO2008117050A1 (en) * | 2007-03-27 | 2008-10-02 | Astrazeneca Ab | Pyrazolyl-amino-substituted pyrazines and their use for the treatment of cancer |
| PA8850801A1 (es) * | 2008-12-17 | 2010-07-27 | Lilly Co Eli | Compuestos útiles para inhibir chk1 |
-
2011
- 2011-10-27 JO JOP/2011/0323A patent/JO3145B1/ar active
- 2011-10-27 AR ARP110103973A patent/AR083575A1/es active IP Right Grant
- 2011-10-28 TW TW100139492A patent/TWI501956B/zh active
- 2011-11-01 EA EA201390499A patent/EA022096B1/ru not_active IP Right Cessation
- 2011-11-01 RS RS20150352A patent/RS54012B1/sr unknown
- 2011-11-01 AU AU2011326230A patent/AU2011326230B2/en active Active
- 2011-11-01 PL PL11788263T patent/PL2638033T3/pl unknown
- 2011-11-01 HR HRP20150530TT patent/HRP20150530T1/hr unknown
- 2011-11-01 CN CN201180053779.8A patent/CN103180311B/zh active Active
- 2011-11-01 BR BR112013010009-5A patent/BR112013010009B1/pt active IP Right Grant
- 2011-11-01 CA CA2816944A patent/CA2816944C/en active Active
- 2011-11-01 MX MX2013005181A patent/MX2013005181A/es active IP Right Grant
- 2011-11-01 PT PT117882639T patent/PT2638033E/pt unknown
- 2011-11-01 ME MEP-2015-69A patent/ME02119B/me unknown
- 2011-11-01 ES ES11788263.9T patent/ES2541414T3/es active Active
- 2011-11-01 JP JP2013537756A patent/JP5792316B2/ja active Active
- 2011-11-01 US US13/877,923 patent/US9067920B2/en active Active
- 2011-11-01 EP EP11788263.9A patent/EP2638033B1/en active Active
- 2011-11-01 KR KR1020137011808A patent/KR101533166B1/ko active Active
- 2011-11-01 DK DK11788263T patent/DK2638033T3/en active
- 2011-11-01 SI SI201130467T patent/SI2638033T1/sl unknown
- 2011-11-01 WO PCT/US2011/058692 patent/WO2012064548A1/en not_active Ceased
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