JP2013539751A5 - - Google Patents
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- Publication number
- JP2013539751A5 JP2013539751A5 JP2013529181A JP2013529181A JP2013539751A5 JP 2013539751 A5 JP2013539751 A5 JP 2013539751A5 JP 2013529181 A JP2013529181 A JP 2013529181A JP 2013529181 A JP2013529181 A JP 2013529181A JP 2013539751 A5 JP2013539751 A5 JP 2013539751A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- aryl
- alkoxy
- nitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 C[C@](C(NCC(N(C)[C@@](c(cc1-c(cc(C[C@@](C(O)=O)NC([C@](C)N2)=O)cc3)c3O)ccc1O)C2=O)=O)=O)NC([C@](CO)N(C)C(*)=O)=O Chemical compound C[C@](C(NCC(N(C)[C@@](c(cc1-c(cc(C[C@@](C(O)=O)NC([C@](C)N2)=O)cc3)c3O)ccc1O)C2=O)=O)=O)NC([C@](CO)N(C)C(*)=O)=O 0.000 description 4
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38298810P | 2010-09-15 | 2010-09-15 | |
| US61/382,988 | 2010-09-15 | ||
| PCT/US2011/049967 WO2012036907A2 (en) | 2010-09-15 | 2011-08-31 | Broad spectrum antibiotic arylomycin analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013539751A JP2013539751A (ja) | 2013-10-28 |
| JP2013539751A5 true JP2013539751A5 (enExample) | 2014-10-16 |
Family
ID=45832167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013529181A Ceased JP2013539751A (ja) | 2010-09-15 | 2011-08-31 | 広域抗生物質アリロマイシン類縁体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9187524B2 (enExample) |
| EP (1) | EP2616093A4 (enExample) |
| JP (1) | JP2013539751A (enExample) |
| KR (1) | KR20130105659A (enExample) |
| CN (1) | CN103209700A (enExample) |
| BR (1) | BR112013006265A2 (enExample) |
| CA (1) | CA2811295A1 (enExample) |
| MX (1) | MX2013003035A (enExample) |
| RU (1) | RU2013112483A (enExample) |
| WO (1) | WO2012036907A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2013003035A (es) | 2010-09-15 | 2013-12-16 | Scripps Research Inst | Analogos de arilomicina como antibióticos de amplio espectro. |
| WO2012166665A2 (en) * | 2011-05-27 | 2012-12-06 | Rqx Pharmaceuticals, Inc. | Broad spectrum antibiotics |
| US10501493B2 (en) | 2011-05-27 | 2019-12-10 | Rqx Pharmaceuticals, Inc. | Broad spectrum antibiotics |
| KR20140140580A (ko) * | 2012-03-14 | 2014-12-09 | 더 스크립스 리서치 인스티튜트 | 광범위 항생제 아릴로마이신 유사체 |
| CA2892027A1 (en) * | 2012-11-21 | 2014-05-30 | Rqx Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
| CN103103261A (zh) * | 2013-01-05 | 2013-05-15 | 张国新 | 检测幽门螺杆菌对克拉霉素耐药性试剂盒及制备方法 |
| KR20170027721A (ko) * | 2014-05-20 | 2017-03-10 | 알큐엑스 파마슈티컬스, 인크. | 마크로시클릭 광범위 항생제 |
| CN107106533B (zh) * | 2014-10-31 | 2020-11-06 | 罗切斯特大学 | 用于治疗微生物感染的增效组合物 |
| KR20180109858A (ko) | 2015-11-20 | 2018-10-08 | 알큐엑스 파마슈티컬스, 인크. | 마크로시클릭 광범위 항생제 |
| WO2017214534A1 (en) | 2016-06-10 | 2017-12-14 | The Scripps Research Institute | Synthesis of the arylomycin macrocyclic core |
| UA126027C2 (uk) * | 2017-02-15 | 2022-08-03 | АрКьюЕкс ФАРМАСЬЮТІКЛС, ІНК. | Макроциклічні антибіотики широкого спектра |
| EP3388445A1 (en) * | 2017-04-10 | 2018-10-17 | F. Hoffmann-La Roche AG | Peptide macrocycles and use thereof in the treatment of bacterial infections |
| IL288294B (en) | 2019-05-28 | 2022-09-01 | Hoffmann La Roche | A broad-spectrum macrocyclic antibiotic |
| CN116023430B (zh) * | 2022-12-20 | 2025-11-25 | 中国药科大学 | 2-(2-(2-苯甲酰氨基)乙酰胺)苯甲酸类衍生物及其制备方法和用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11514527A (ja) | 1995-11-03 | 1999-12-14 | イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー | バキルス エスピー（Ｂａｃｉｌｌｕｓ ｓｐ．）用の陽性選択ベクター |
| US6951840B2 (en) * | 2001-08-31 | 2005-10-04 | Eli Lilly And Company | Lipoglycopeptide antibiotics |
| DE102005014245A1 (de) | 2005-03-30 | 2006-10-05 | Aicuris Gmbh & Co. Kg | Antibakterielle Amid-Makrozyklen V |
| CN102939095A (zh) * | 2010-03-09 | 2013-02-20 | 默沙东公司 | 增强β-内酰胺抗菌药物的活性的桥联脂糖肽类 |
| MX2013003035A (es) | 2010-09-15 | 2013-12-16 | Scripps Research Inst | Analogos de arilomicina como antibióticos de amplio espectro. |
| WO2012166665A2 (en) | 2011-05-27 | 2012-12-06 | Rqx Pharmaceuticals, Inc. | Broad spectrum antibiotics |
| KR20140140580A (ko) | 2012-03-14 | 2014-12-09 | 더 스크립스 리서치 인스티튜트 | 광범위 항생제 아릴로마이신 유사체 |
-
2011
- 2011-08-31 MX MX2013003035A patent/MX2013003035A/es not_active Application Discontinuation
- 2011-08-31 CN CN2011800550186A patent/CN103209700A/zh active Pending
- 2011-08-31 JP JP2013529181A patent/JP2013539751A/ja not_active Ceased
- 2011-08-31 CA CA2811295A patent/CA2811295A1/en not_active Abandoned
- 2011-08-31 BR BR112013006265A patent/BR112013006265A2/pt not_active IP Right Cessation
- 2011-08-31 EP EP11825668.4A patent/EP2616093A4/en not_active Withdrawn
- 2011-08-31 KR KR1020137009510A patent/KR20130105659A/ko not_active Withdrawn
- 2011-08-31 RU RU2013112483/04A patent/RU2013112483A/ru not_active Application Discontinuation
- 2011-08-31 US US13/821,195 patent/US9187524B2/en not_active Expired - Fee Related
- 2011-08-31 WO PCT/US2011/049967 patent/WO2012036907A2/en not_active Ceased
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