JP2013539359A5 - - Google Patents
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- JP2013539359A5 JP2013539359A5 JP2013519749A JP2013519749A JP2013539359A5 JP 2013539359 A5 JP2013539359 A5 JP 2013539359A5 JP 2013519749 A JP2013519749 A JP 2013519749A JP 2013519749 A JP2013519749 A JP 2013519749A JP 2013539359 A5 JP2013539359 A5 JP 2013539359A5
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- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 claims description 219
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 claims description 219
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36358610P | 2010-07-12 | 2010-07-12 | |
| US36358910P | 2010-07-12 | 2010-07-12 | |
| US36358310P | 2010-07-12 | 2010-07-12 | |
| US61/363,589 | 2010-07-12 | ||
| US61/363,583 | 2010-07-12 | ||
| US61/363,586 | 2010-07-12 | ||
| PCT/US2011/043596 WO2012009289A2 (en) | 2010-07-12 | 2011-07-11 | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015170197A Division JP2016053018A (ja) | 2010-07-12 | 2015-08-31 | アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013539359A JP2013539359A (ja) | 2013-10-24 |
| JP2013539359A5 true JP2013539359A5 (enExample) | 2014-05-22 |
| JP5991973B2 JP5991973B2 (ja) | 2016-09-14 |
Family
ID=45470021
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013519749A Active JP5991973B2 (ja) | 2010-07-12 | 2011-07-11 | アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| JP2015170197A Withdrawn JP2016053018A (ja) | 2010-07-12 | 2015-08-31 | アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015170197A Withdrawn JP2016053018A (ja) | 2010-07-12 | 2015-08-31 | アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US8969301B2 (enExample) |
| EP (1) | EP2593124B1 (enExample) |
| JP (2) | JP5991973B2 (enExample) |
| KR (2) | KR102099730B1 (enExample) |
| CN (1) | CN103124561B (enExample) |
| AU (1) | AU2011279392C1 (enExample) |
| CA (1) | CA2804278C (enExample) |
| EA (1) | EA030461B1 (enExample) |
| NZ (1) | NZ603811A (enExample) |
| WO (1) | WO2012009289A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010099477A2 (en) | 2009-02-27 | 2010-09-02 | Atyr Pharma, Inc. | Polypeptide structural motifs associated with cell signaling activity |
| WO2010120509A2 (en) | 2009-03-31 | 2010-10-21 | Atyr Pharma, Inc. | Compositions and methods comprising aspartyl-trna synthetases having non-canonical biological activities |
| CN103118692A (zh) | 2010-04-26 | 2013-05-22 | Atyr医药公司 | 与半胱氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| JP6240500B2 (ja) | 2010-04-27 | 2017-11-29 | エータイアー ファーマ， インコーポレイテッド | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| CA2797362C (en) | 2010-04-27 | 2020-12-08 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases |
| CN103097524B (zh) | 2010-04-28 | 2016-08-03 | Atyr医药公司 | 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| AU2011248457B2 (en) | 2010-04-29 | 2017-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl tRNA synthetases |
| US8986680B2 (en) | 2010-04-29 | 2015-03-24 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases |
| CN103096925A (zh) | 2010-05-03 | 2013-05-08 | Atyr医药公司 | 与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| ES2623805T3 (es) | 2010-05-03 | 2017-07-12 | Atyr Pharma, Inc. | Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de fenilalanil-alfa-ARNt sintetasas |
| WO2011139988A2 (en) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-trna synthetases |
| EP2566496B1 (en) | 2010-05-03 | 2018-02-28 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases |
| CN102985103A (zh) | 2010-05-04 | 2013-03-20 | Atyr医药公司 | 与p38多-tRNA合成酶复合物相关的治疗、诊断和抗体组合物的创新发现 |
| EP2566492B1 (en) | 2010-05-04 | 2016-10-26 | aTyr Pharma, Inc. | Innovative discovery of therapeutic compositions related to protein fragments of glutamyl-prolyl-trna synthetases |
| CA2799197C (en) | 2010-05-14 | 2019-10-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases |
| CA2799480C (en) | 2010-05-17 | 2020-12-15 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-trna synthetases |
| CA2800375C (en) | 2010-05-27 | 2021-03-09 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases |
| CN103118694B (zh) | 2010-06-01 | 2016-08-03 | Atyr医药公司 | 与赖氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现 |
| US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| WO2012021249A2 (en) | 2010-07-12 | 2012-02-16 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
| AU2011289831C1 (en) | 2010-07-12 | 2017-06-15 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| KR102099730B1 (ko) | 2010-07-12 | 2020-04-16 | 에이티와이알 파마, 인코포레이티드 | 아스파르틸trna 합성효소의 단백질 단편에 관련된 치료적, 진단적, 및 항체 조성물의 혁신적 발견 |
| AU2011293294B2 (en) | 2010-08-25 | 2016-03-24 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Tyrosyl-tRNA synthetases |
| CA2812795C (en) | 2010-10-06 | 2021-08-31 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases |
| WO2012158945A2 (en) * | 2011-05-19 | 2012-11-22 | The Scripps Research Institute | Compositions and methods for treating charcot-marie-tooth diseases and related neuronal diseases |
| US9714419B2 (en) | 2011-08-09 | 2017-07-25 | Atyr Pharma, Inc. | PEGylated tyrosyl-tRNA synthetase polypeptides |
| WO2013086228A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Pegylated aspartyl-trna synthetase polypeptides |
| WO2013086216A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Improved aspartyl-trna synthetases |
| EP2797959A4 (en) * | 2011-12-29 | 2015-08-26 | Atyr Pharma Inc | ASPARTYL-tRNA synthetase FC CONJUGATES |
| ES2847383T3 (es) | 2013-03-15 | 2021-08-03 | Atyr Pharma Inc | Conjugados de Fc-histidil-ARNt sintetasa |
| JP6792001B2 (ja) * | 2016-07-01 | 2020-11-25 | メディシナル バイオコンバージェンス リサーチ センター | アミノアシルｔＲＮＡ合成酵素関連タンパク質発現水準を利用した甲状腺瀘胞癌診断用組成物と診断マーカー検出方法 |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| ES2994451T3 (en) | 2017-04-20 | 2025-01-24 | Atyr Pharma Inc | Compositions for treating lung inflammation |
| KR102167755B1 (ko) * | 2018-05-23 | 2020-10-19 | 주식회사 큐어바이오 | 단편화된 grs 폴리펩타이드, 이의 변이체 및 이들의 용도 |
| CA3106563A1 (en) * | 2018-07-26 | 2020-01-30 | Atyr Pharma, Inc. | Compositions and methods for treating nrp2-associated diseases |
| CN115786284B (zh) * | 2021-09-09 | 2025-12-30 | 中国科学院微生物研究所 | 来源于水稻的稻瘟菌和白叶枯病菌抗病性相关蛋白及其编码基因和应用 |
| GB202318158D0 (en) * | 2023-11-28 | 2024-01-10 | Univ Surrey | Cancer therapy |
| WO2025122621A1 (en) * | 2023-12-04 | 2025-06-12 | North Carolina State University | Compositions and methods related to aptamers and aptamer-based sensors |
Family Cites Families (142)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| AU2013221317B2 (en) | 2012-02-16 | 2017-07-06 | Pangu Biopharma Limited | Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases |
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2011
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2015
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2016
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2019
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