JP5991973B2 - アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 - Google Patents

アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 Download PDF

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JP5991973B2
JP5991973B2 JP2013519749A JP2013519749A JP5991973B2 JP 5991973 B2 JP5991973 B2 JP 5991973B2 JP 2013519749 A JP2013519749 A JP 2013519749A JP 2013519749 A JP2013519749 A JP 2013519749A JP 5991973 B2 JP5991973 B2 JP 5991973B2
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aars
polypeptide
protein
asprs
cell
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JP2013539359A5 (enExample
JP2013539359A (ja
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レスリー アン グリーン，
レスリー アン グリーン，
カイル ピー． チャン，
カイル ピー． チャン，
フェイ ホン，
フェイ ホン，
アレイン ピー． バサロット，
アレイン ピー． バサロット，
ウィン−セー ロー，
ウィン−セー ロー，
ジェフリー ディー． ワトキンス，
ジェフリー ディー． ワトキンス，
シェリル エル． クイン，
シェリル エル． クイン，
ジョン ディー． メンドレイン，
ジョン ディー． メンドレイン，
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エータイアー ファーマ， インコーポレイテッド
エータイアー ファーマ， インコーポレイテッド
パング バイオファーマ リミテッド
パング バイオファーマ リミテッド
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2319/00—Fusion polypeptide
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    • C12Y—ENZYMES
    • C12Y601/00—Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01—Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/9015—Ligases (6)

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JP2013519749A 2010-07-12 2011-07-11 アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 Active JP5991973B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US36358310P 2010-07-12 2010-07-12
US36358610P 2010-07-12 2010-07-12
US36358910P 2010-07-12 2010-07-12
US61/363,589 2010-07-12
US61/363,586 2010-07-12
US61/363,583 2010-07-12
PCT/US2011/043596 WO2012009289A2 (en) 2010-07-12 2011-07-11 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases

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JP2015170197A Division JP2016053018A (ja) 2010-07-12 2015-08-31 アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見

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JP2013539359A JP2013539359A (ja) 2013-10-24
JP2013539359A5 JP2013539359A5 (enExample) 2014-05-22
JP5991973B2 true JP5991973B2 (ja) 2016-09-14

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JP2015170197A Withdrawn JP2016053018A (ja) 2010-07-12 2015-08-31 アスパルチルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見

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US (4) US8969301B2 (enExample)
EP (1) EP2593124B1 (enExample)
JP (2) JP5991973B2 (enExample)
KR (2) KR102099730B1 (enExample)
CN (1) CN103124561B (enExample)
AU (1) AU2011279392C1 (enExample)
CA (1) CA2804278C (enExample)
EA (1) EA030461B1 (enExample)
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JP6066900B2 (ja) 2010-04-26 2017-01-25 エータイアー ファーマ， インコーポレイテッド システイニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
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KR20130102534A (ko) 2010-07-12 2013-09-17 에이티와이알 파마, 인코포레이티드 히스티딜­trna 합성효소의 단백질 단편에 관련된 치료적, 진단적, 및 항체 조성물의 혁신적 발견
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