JP2013531973A5 - - Google Patents
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- JP2013531973A5 JP2013531973A5 JP2013508229A JP2013508229A JP2013531973A5 JP 2013531973 A5 JP2013531973 A5 JP 2013531973A5 JP 2013508229 A JP2013508229 A JP 2013508229A JP 2013508229 A JP2013508229 A JP 2013508229A JP 2013531973 A5 JP2013531973 A5 JP 2013531973A5
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- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 claims description 215
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 claims description 215
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32837110P | 2010-04-27 | 2010-04-27 | |
| US32837310P | 2010-04-27 | 2010-04-27 | |
| US32836910P | 2010-04-27 | 2010-04-27 | |
| US61/328,373 | 2010-04-27 | ||
| US61/328,371 | 2010-04-27 | ||
| US61/328,369 | 2010-04-27 | ||
| PCT/US2011/034207 WO2011139801A2 (en) | 2010-04-27 | 2011-04-27 | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl trna synthetases |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015142866A Division JP2015186486A (ja) | 2010-04-27 | 2015-07-17 | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| JP2017163371A Division JP2017201994A (ja) | 2010-04-27 | 2017-08-28 | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013531973A JP2013531973A (ja) | 2013-08-15 |
| JP2013531973A5 true JP2013531973A5 (enExample) | 2014-05-22 |
| JP6240500B2 JP6240500B2 (ja) | 2017-11-29 |
Family
ID=44904372
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508229A Active JP6240500B2 (ja) | 2010-04-27 | 2011-04-27 | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| JP2015142866A Pending JP2015186486A (ja) | 2010-04-27 | 2015-07-17 | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| JP2017163371A Withdrawn JP2017201994A (ja) | 2010-04-27 | 2017-08-28 | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015142866A Pending JP2015186486A (ja) | 2010-04-27 | 2015-07-17 | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| JP2017163371A Withdrawn JP2017201994A (ja) | 2010-04-27 | 2017-08-28 | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8986681B2 (enExample) |
| EP (1) | EP2563382B1 (enExample) |
| JP (3) | JP6240500B2 (enExample) |
| CN (2) | CN108165537A (enExample) |
| AU (1) | AU2011248521B2 (enExample) |
| CA (1) | CA2797259C (enExample) |
| ES (1) | ES2638311T3 (enExample) |
| WO (1) | WO2011139801A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010099477A2 (en) | 2009-02-27 | 2010-09-02 | Atyr Pharma, Inc. | Polypeptide structural motifs associated with cell signaling activity |
| CN103118692A (zh) | 2010-04-26 | 2013-05-22 | Atyr医药公司 | 与半胱氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| CA2797362C (en) | 2010-04-27 | 2020-12-08 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases |
| JP6240500B2 (ja) | 2010-04-27 | 2017-11-29 | エータイアー ファーマ， インコーポレイテッド | スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| CN103097524B (zh) | 2010-04-28 | 2016-08-03 | Atyr医药公司 | 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| US8986680B2 (en) | 2010-04-29 | 2015-03-24 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases |
| AU2011248457B2 (en) | 2010-04-29 | 2017-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl tRNA synthetases |
| ES2623805T3 (es) | 2010-05-03 | 2017-07-12 | Atyr Pharma, Inc. | Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de fenilalanil-alfa-ARNt sintetasas |
| CN103096925A (zh) | 2010-05-03 | 2013-05-08 | Atyr医药公司 | 与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| WO2011139988A2 (en) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-trna synthetases |
| EP2566496B1 (en) | 2010-05-03 | 2018-02-28 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases |
| CN102985103A (zh) | 2010-05-04 | 2013-03-20 | Atyr医药公司 | 与p38多-tRNA合成酶复合物相关的治疗、诊断和抗体组合物的创新发现 |
| EP2566492B1 (en) | 2010-05-04 | 2016-10-26 | aTyr Pharma, Inc. | Innovative discovery of therapeutic compositions related to protein fragments of glutamyl-prolyl-trna synthetases |
| CA2799197C (en) | 2010-05-14 | 2019-10-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases |
| CA2799480C (en) | 2010-05-17 | 2020-12-15 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-trna synthetases |
| CA2800375C (en) | 2010-05-27 | 2021-03-09 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases |
| CN103118694B (zh) | 2010-06-01 | 2016-08-03 | Atyr医药公司 | 与赖氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现 |
| AU2011289831C1 (en) | 2010-07-12 | 2017-06-15 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| KR102099730B1 (ko) | 2010-07-12 | 2020-04-16 | 에이티와이알 파마, 인코포레이티드 | 아스파르틸trna 합성효소의 단백질 단편에 관련된 치료적, 진단적, 및 항체 조성물의 혁신적 발견 |
| US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| WO2012021249A2 (en) | 2010-07-12 | 2012-02-16 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
| AU2011293294B2 (en) | 2010-08-25 | 2016-03-24 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Tyrosyl-tRNA synthetases |
| CA2812795C (en) | 2010-10-06 | 2021-08-31 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases |
| WO2012158945A2 (en) * | 2011-05-19 | 2012-11-22 | The Scripps Research Institute | Compositions and methods for treating charcot-marie-tooth diseases and related neuronal diseases |
| US9714419B2 (en) | 2011-08-09 | 2017-07-25 | Atyr Pharma, Inc. | PEGylated tyrosyl-tRNA synthetase polypeptides |
| WO2013086228A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Pegylated aspartyl-trna synthetase polypeptides |
| WO2013086216A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Improved aspartyl-trna synthetases |
| EP2797959A4 (en) | 2011-12-29 | 2015-08-26 | Atyr Pharma Inc | ASPARTYL-tRNA synthetase FC CONJUGATES |
| WO2014018619A1 (en) * | 2012-07-25 | 2014-01-30 | University Of Vermont And State Agricultural College | Methods and compounds for increasing threonyl-trna synthetase activity |
| US10087435B2 (en) | 2012-07-25 | 2018-10-02 | University Of Vermont And State Agricultural College | Methods and compounds for reducing threonyl-tRNA synthetase activity |
| WO2014018618A1 (en) | 2012-07-25 | 2014-01-30 | University Of Vermont And State Agricultural College | Methods and compounds for diagnosing threonyl-trna synthetase-associated diseases and conditions |
| ES2847383T3 (es) | 2013-03-15 | 2021-08-03 | Atyr Pharma Inc | Conjugados de Fc-histidil-ARNt sintetasa |
| ES2994451T3 (en) | 2017-04-20 | 2025-01-24 | Atyr Pharma Inc | Compositions for treating lung inflammation |
| WO2019055594A1 (en) | 2017-09-13 | 2019-03-21 | North Carolina State University | BRUSHING ADIPOSE TISSUE INDUCED LOCALLY BY MICRO-NEEDLE STAMPS FOR THE TREATMENT OF OBESITY |
| CN110317867A (zh) * | 2019-07-11 | 2019-10-11 | 德阳市人民医院 | Tars作为诊断男性骨质疏松症的分子标志物的应用 |
| CN110567861B (zh) * | 2019-09-09 | 2021-12-21 | 浙江普罗亭健康科技有限公司 | 基于质谱流式检测技术筛查具有免疫原性抗原肽的试剂盒及检测方法 |
| KR102671044B1 (ko) * | 2020-03-25 | 2024-05-31 | 한국생명공학연구원 | 아커만시아 뮤시니필라 유래의 tars 또는 이의 단편 및 이의 용도 |
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| AU2013221317B2 (en) | 2012-02-16 | 2017-07-06 | Pangu Biopharma Limited | Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases |
| US20140066321A1 (en) | 2012-07-23 | 2014-03-06 | Pangu Biopharma Limited | Structures of human histidyl-trna synthetase and methods of use |
| ES2847383T3 (es) | 2013-03-15 | 2021-08-03 | Atyr Pharma Inc | Conjugados de Fc-histidil-ARNt sintetasa |
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2011
- 2011-04-27 JP JP2013508229A patent/JP6240500B2/ja active Active
- 2011-04-27 ES ES11777984.3T patent/ES2638311T3/es active Active
- 2011-04-27 CN CN201711430252.8A patent/CN108165537A/zh active Pending
- 2011-04-27 CA CA2797259A patent/CA2797259C/en active Active
- 2011-04-27 EP EP11777984.3A patent/EP2563382B1/en active Active
- 2011-04-27 WO PCT/US2011/034207 patent/WO2011139801A2/en not_active Ceased
- 2011-04-27 CN CN2011800303013A patent/CN103096910A/zh active Pending
- 2011-04-27 AU AU2011248521A patent/AU2011248521B2/en active Active
- 2011-04-27 US US13/643,750 patent/US8986681B2/en active Active
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2015
- 2015-02-11 US US14/619,722 patent/US9580706B2/en active Active
- 2015-07-17 JP JP2015142866A patent/JP2015186486A/ja active Pending
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2017
- 2017-01-12 US US15/404,682 patent/US10150958B2/en active Active
- 2017-08-28 JP JP2017163371A patent/JP2017201994A/ja not_active Withdrawn
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2018
- 2018-10-25 US US16/171,087 patent/US10563192B2/en active Active
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