JP2013538863A5 - - Google Patents
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- Publication number
- JP2013538863A5 JP2013538863A5 JP2013532104A JP2013532104A JP2013538863A5 JP 2013538863 A5 JP2013538863 A5 JP 2013538863A5 JP 2013532104 A JP2013532104 A JP 2013532104A JP 2013532104 A JP2013532104 A JP 2013532104A JP 2013538863 A5 JP2013538863 A5 JP 2013538863A5
- Authority
- JP
- Japan
- Prior art keywords
- fii
- fibrinogen
- fviia
- medicament according
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 28
- 108010049003 Fibrinogen Proteins 0.000 claims 16
- 102000008946 Fibrinogen Human genes 0.000 claims 16
- 229940012952 fibrinogen Drugs 0.000 claims 16
- 102000015081 Blood Coagulation Factors Human genes 0.000 claims 14
- 108010039209 Blood Coagulation Factors Proteins 0.000 claims 14
- 239000003114 blood coagulation factor Substances 0.000 claims 14
- 239000008280 blood Substances 0.000 claims 8
- 210000004369 blood Anatomy 0.000 claims 8
- 230000001225 therapeutic effect Effects 0.000 claims 8
- 241000124008 Mammalia Species 0.000 claims 7
- 206010053567 Coagulopathies Diseases 0.000 claims 5
- 208000024659 Hemostatic disease Diseases 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 208000032843 Hemorrhage Diseases 0.000 claims 3
- 208000034158 bleeding Diseases 0.000 claims 3
- 230000000740 bleeding effect Effects 0.000 claims 3
- 208000015294 blood coagulation disease Diseases 0.000 claims 3
- 230000009852 coagulant defect Effects 0.000 claims 3
- 208000012908 vascular hemostatic disease Diseases 0.000 claims 3
- 206010053476 Traumatic haemorrhage Diseases 0.000 claims 2
- 230000035602 clotting Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 208000031169 hemorrhagic disease Diseases 0.000 claims 2
- 230000023597 hemostasis Effects 0.000 claims 2
- 208000031220 Hemophilia Diseases 0.000 claims 1
- 208000009292 Hemophilia A Diseases 0.000 claims 1
- 101001052793 Homo sapiens GDP-L-fucose synthase Proteins 0.000 claims 1
- 206010051077 Post procedural haemorrhage Diseases 0.000 claims 1
- 208000018525 Postpartum Hemorrhage Diseases 0.000 claims 1
- 108090000190 Thrombin Proteins 0.000 claims 1
- 238000011260 co-administration Methods 0.000 claims 1
- 230000015271 coagulation Effects 0.000 claims 1
- 238000005345 coagulation Methods 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 239000012895 dilution Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000000004 hemodynamic effect Effects 0.000 claims 1
- 102000050085 human TSTA3 Human genes 0.000 claims 1
- 238000004904 shortening Methods 0.000 claims 1
- 229960004072 thrombin Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39022410P | 2010-10-06 | 2010-10-06 | |
| US61/390,224 | 2010-10-06 | ||
| PCT/EP2011/066241 WO2012045569A1 (en) | 2010-10-06 | 2011-09-19 | Factor ii and fibrinogen for treatment of haemostatic disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013538863A JP2013538863A (ja) | 2013-10-17 |
| JP2013538863A5 true JP2013538863A5 (https=) | 2014-11-20 |
| JP6000259B2 JP6000259B2 (ja) | 2016-09-28 |
Family
ID=44677879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532104A Expired - Fee Related JP6000259B2 (ja) | 2010-10-06 | 2011-09-19 | 止血障害治療用第ｉｉ因子およびフィブリノーゲン |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9433664B2 (https=) |
| EP (1) | EP2624859B1 (https=) |
| JP (1) | JP6000259B2 (https=) |
| KR (1) | KR20130136988A (https=) |
| CN (1) | CN103221061A (https=) |
| AU (1) | AU2011313505B2 (https=) |
| BR (1) | BR112013008034A2 (https=) |
| CA (1) | CA2812888A1 (https=) |
| DK (1) | DK2624859T3 (https=) |
| ES (1) | ES2625153T3 (https=) |
| HU (1) | HUE033204T2 (https=) |
| MX (1) | MX343784B (https=) |
| PL (1) | PL2624859T3 (https=) |
| RU (1) | RU2606155C2 (https=) |
| SG (2) | SG188639A1 (https=) |
| WO (1) | WO2012045569A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12171463B2 (en) | 2008-10-03 | 2024-12-24 | Femasys Inc. | Contrast agent generation and injection system for sonographic imaging |
| CN103221061A (zh) | 2010-10-06 | 2013-07-24 | 米迪缪尼有限公司 | 用于治疗止血障碍的因子ii以及纤维蛋白原 |
| IL230150A0 (en) * | 2013-12-24 | 2014-09-30 | Omrix Biopharmaceuticals Ltd | One-component fibrin glue containing zymogens |
| DK3579857T3 (da) | 2017-02-09 | 2022-06-07 | Csl Behring Gmbh | Et blodkoagulationsfaktorerstatningsprodukt til anvendelse ved behandling eller profylakse af blødninger |
| CN116059431A (zh) * | 2021-10-29 | 2023-05-05 | 丁琴琴 | 一种含凝血因子的双层止血敷料及其制备方法 |
| WO2023220412A1 (en) * | 2022-05-13 | 2023-11-16 | Cedars-Sinai Medical Center | Hemostatic monitor |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0044343B1 (en) | 1980-01-28 | 1984-08-22 | Baxter Travenol Laboratories, Inc. | Prothrombin-containing therapeutic compositions and methods of producing enzymatically active blood clotting factors from prothrombin-containing blood fractions |
| US4501731A (en) | 1983-06-27 | 1985-02-26 | Tishkoff Garson H | Treatment of disparate bleeding disorders with factor X zymogen |
| DE4430204A1 (de) | 1994-08-26 | 1996-02-29 | Behringwerke Ag | Arzneimittel, welches als Gegenmittel für Blut-Antikoagulanzien geeignet ist und seine Verwendung |
| DK0796623T3 (da) | 1996-03-20 | 2005-08-01 | Baxter Ag | Farmaceutisk præparat til behandling af blodkoagulationslidelser |
| AT409334B (de) | 1997-09-19 | 2002-07-25 | Immuno Ag | Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren |
| US7094428B2 (en) | 2000-06-16 | 2006-08-22 | The University Of Medicine And Dentistry Of New Jersey | Hemostatic compositions, devices and methods |
| US6825323B2 (en) | 2001-01-10 | 2004-11-30 | The United States Of America As Represented By The Secretary Of The Army | Compositions for treatment of hemorrhaging with activated factor VIIa in combination with fibrinogen and methods of using same |
| BR0207007A (pt) | 2001-02-05 | 2004-02-17 | Novo Nordisk Healthcare Ag | Composição farmcêutica, kit, usos de uma preparação e de uma composição, e, métodos para tratar de episódios de hemorragia em um paciente, para reduzir o tempo de coagulação em um paciente, para intensificar a hemostasia em um paciente para reduzir o número de administrações da proteìna do fator de coagulação necessário para deter a hemorragia e manter a hemostasia em um paciente, para reduzir a quantidade de proteìna do fator de coagulação administrada necessária para deter a hemorragia e manter a hemostasia em um paciente, para prolongar o tempo de lise do coágulo em um paciente, para aumentar a resistência do coágulo em paciente e para intensificar a formação de coágulo de fibrina em um paciente |
| US20060025336A1 (en) | 2001-07-16 | 2006-02-02 | Novo Nordisk A/S | Pharmaceutical compositions comprising combinations of factor VII polypeptides and aprotinin polypeptides |
| AU2002354846B2 (en) | 2001-07-20 | 2007-08-02 | Novo Nordisk Health Care Ag | Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides |
| US20040101546A1 (en) * | 2002-11-26 | 2004-05-27 | Gorman Anne Jessica | Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents |
| WO2004060172A1 (en) | 2002-12-31 | 2004-07-22 | Marine Polymer Technologies, Inc. | Hemostatic compositions and uses therefor |
| GB0324044D0 (en) | 2003-10-14 | 2003-11-19 | Astrazeneca Ab | Protein |
| US7211559B2 (en) | 2003-10-31 | 2007-05-01 | University Of Maryland, Baltimore | Factor VIII compositions and methods |
| ES2399277T3 (es) | 2004-05-27 | 2013-03-27 | Baxter International Inc. | Procedimiento de tratamiento de trastornos hemorrágicos utilizando polisacáridos sulfatados |
| WO2006114105A2 (en) | 2005-04-26 | 2006-11-02 | Maxygen Holdings Ltd. | Use of modified factor vii for treating bleeding |
| MX2008006313A (es) | 2005-11-15 | 2008-11-06 | Philadelphia Children Hospital | Metodos y composiciones para modular la hemostasia. |
| WO2007103447A2 (en) * | 2006-03-06 | 2007-09-13 | Humagene, Inc. | A method for the preparation of recombinant human thrombin |
| US20080014251A1 (en) | 2006-07-14 | 2008-01-17 | Advanced Vascular Dynamics | Hemostatic compound and its use |
| US20090148502A1 (en) | 2006-10-23 | 2009-06-11 | Hemo Nanoscience, Llc | Compositions and methods for treating lacerations, abrasions, avulsions, burns, ulcers, and cases of excessive bleeding |
| EP1935429A1 (en) | 2006-12-22 | 2008-06-25 | CSL Behring GmbH | Synergistic therapeutic use of prothrombin complex concentrates with FVIII concentrates |
| AU2008233111A1 (en) | 2007-03-30 | 2008-10-09 | Thrombodyne, Inc. | Methods of making concentrated fibrinogen containing compositions and associated systems for preparing fibrin glue |
| CA2683443A1 (en) | 2007-04-13 | 2008-10-23 | Catalyst Biosciences, Inc. | Modified factor vii polypeptides and uses thereof |
| US8852558B2 (en) | 2008-03-11 | 2014-10-07 | Materials Modification, Inc. | In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide and platinum catalyst |
| WO2010042741A1 (en) | 2008-10-08 | 2010-04-15 | Thrombodyne, Inc. | Methods of making concentrated fibrinogen- and platelet containing compositions |
| CN103221061A (zh) | 2010-10-06 | 2013-07-24 | 米迪缪尼有限公司 | 用于治疗止血障碍的因子ii以及纤维蛋白原 |
-
2011
- 2011-09-19 CN CN2011800479754A patent/CN103221061A/zh active Pending
- 2011-09-19 ES ES11761051.9T patent/ES2625153T3/es active Active
- 2011-09-19 JP JP2013532104A patent/JP6000259B2/ja not_active Expired - Fee Related
- 2011-09-19 KR KR1020137008520A patent/KR20130136988A/ko not_active Ceased
- 2011-09-19 BR BR112013008034A patent/BR112013008034A2/pt not_active IP Right Cessation
- 2011-09-19 EP EP11761051.9A patent/EP2624859B1/en not_active Revoked
- 2011-09-19 WO PCT/EP2011/066241 patent/WO2012045569A1/en not_active Ceased
- 2011-09-19 CA CA2812888A patent/CA2812888A1/en not_active Abandoned
- 2011-09-19 RU RU2013120033A patent/RU2606155C2/ru not_active IP Right Cessation
- 2011-09-19 PL PL11761051T patent/PL2624859T3/pl unknown
- 2011-09-19 SG SG2013021498A patent/SG188639A1/en unknown
- 2011-09-19 US US13/877,854 patent/US9433664B2/en not_active Expired - Fee Related
- 2011-09-19 AU AU2011313505A patent/AU2011313505B2/en not_active Ceased
- 2011-09-19 MX MX2013003715A patent/MX343784B/es active IP Right Grant
- 2011-09-19 DK DK11761051.9T patent/DK2624859T3/en active
- 2011-09-19 SG SG10201508159SA patent/SG10201508159SA/en unknown
- 2011-09-19 HU HUE11761051A patent/HUE033204T2/en unknown
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