JP2013536235A5 - - Google Patents
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- Publication number
- JP2013536235A5 JP2013536235A5 JP2013526084A JP2013526084A JP2013536235A5 JP 2013536235 A5 JP2013536235 A5 JP 2013536235A5 JP 2013526084 A JP2013526084 A JP 2013526084A JP 2013526084 A JP2013526084 A JP 2013526084A JP 2013536235 A5 JP2013536235 A5 JP 2013536235A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently
- groups
- alkoxy
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(*)(c1n[o]c(*)n1)c1ccc(*)cc1* Chemical compound *C(*)(c1n[o]c(*)n1)c1ccc(*)cc1* 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37718110P | 2010-08-26 | 2010-08-26 | |
| US61/377,181 | 2010-08-26 | ||
| US201161511247P | 2011-07-25 | 2011-07-25 | |
| US61/511,247 | 2011-07-25 | ||
| PCT/US2011/048743 WO2012027322A1 (en) | 2010-08-26 | 2011-08-23 | Oxadiazole inhibitors of leukotriene production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013536235A JP2013536235A (ja) | 2013-09-19 |
| JP2013536235A5 true JP2013536235A5 (enExample) | 2014-10-09 |
| JP5862669B2 JP5862669B2 (ja) | 2016-02-16 |
Family
ID=44533215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013526084A Active JP5862669B2 (ja) | 2010-08-26 | 2011-08-23 | ロイコトリエン産生のオキサジアゾール阻害剤 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8580829B2 (enExample) |
| EP (1) | EP2609092B1 (enExample) |
| JP (1) | JP5862669B2 (enExample) |
| WO (1) | WO2012027322A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011292285A1 (en) | 2010-08-16 | 2013-01-31 | Boehringer Ingelheim International Gmbh | Oxadiazole inhibitors of leukotriene production |
| EP2609092B1 (en) | 2010-08-26 | 2015-04-01 | Boehringer Ingelheim International GmbH | Oxadiazole inhibitors of leukotriene production |
| BR112013008638A2 (pt) * | 2010-09-23 | 2016-06-21 | Boehringer Ingelheim Int | inibidores de oxadiazol de produção de leucotrieno |
| US8580825B2 (en) * | 2010-09-23 | 2013-11-12 | Boehringer Ingelheim International Gmbh | Oxadiazole inhibitors of leukotriene production |
| WO2013116182A1 (en) * | 2012-01-31 | 2013-08-08 | Boehringer Ingelheim International Gmbh | Heterocyclic compounds as inhibitors of leukotriene production |
| AR089853A1 (es) | 2012-02-01 | 2014-09-24 | Boehringer Ingelheim Int | Inhibidores de oxadiazol de la produccion de leucotrienos para terapia de combinacion, composicion farmaceutica, uso |
| US8716226B2 (en) | 2012-07-18 | 2014-05-06 | Saint Louis University | 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists |
| US9085606B2 (en) | 2012-07-18 | 2015-07-21 | Saint Louis University | Beta amino acid derivatives as integrin antagonists |
| WO2014121055A2 (en) * | 2013-02-04 | 2014-08-07 | Janssen Pharmaceutica Nv | Flap modulators |
| TWI624467B (zh) | 2013-10-14 | 2018-05-21 | 衛材Ｒ＆Ｄ企管股份有限公司 | 選擇性經取代之喹啉化合物 |
| US9663486B2 (en) | 2013-10-14 | 2017-05-30 | Eisai R&D Management Co., Ltd. | Selectively substituted quinoline compounds |
| JP6244036B2 (ja) * | 2014-01-21 | 2017-12-06 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 呼吸器合胞体ウイルス感染症の処置および予防のためのイミダゾール |
| JP6195684B2 (ja) | 2014-06-03 | 2017-09-13 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | ピラゾール化合物及びｔ型カルシウムチャンネルブロッカーとしてのそれらの使用 |
| AU2016381336A1 (en) | 2015-12-30 | 2018-06-28 | Saint Louis University | Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists |
| LT3554490T (lt) | 2016-12-16 | 2022-04-25 | Idorsia Pharmaceuticals Ltd | Farmacinis derinys, apimantis t tipo kalcio kanalo blokatorių |
| CA3050348A1 (en) | 2017-02-06 | 2018-08-09 | Idorsia Pharmaceuticals Ltd | A novel process for the synthesis of 1-aryl-1-trifluoromethylcyclopropanes |
| WO2019027856A1 (en) * | 2017-08-02 | 2019-02-07 | Merck Sharp & Dohme Corp. | NOVEL SUBSTITUTED PYRIDINE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) |
| WO2019027855A1 (en) * | 2017-08-02 | 2019-02-07 | Merck Sharp & Dohme Corp. | NOVEL SUBSTITUTED PHENYL COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) |
| JP7805983B2 (ja) | 2022-03-22 | 2026-01-26 | アッヴィ・インコーポレイテッド | ブルトン型チロシンキナーゼを分解するためのピリミジン |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200200310T2 (tr) | 1999-08-06 | 2002-08-21 | Janssen Pharmaceutica N.V. | Interlökin-5 inhibe eden 6-azaurasil türevleri. |
| US7319108B2 (en) | 2004-01-25 | 2008-01-15 | Sanofi-Aventis Deutschland Gmbh | Aryl-substituted heterocycles, process for their preparation and their use as medicaments |
| WO2006044602A2 (en) * | 2004-10-18 | 2006-04-27 | Merck & Co., Inc. | Diphenyl substituted alkanes as flap inhiibitors |
| US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| US7977359B2 (en) * | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| EP2013174B1 (en) | 2006-04-11 | 2013-05-08 | Merck Sharp & Dohme Corp. | Diaryl substituted alkanes |
| ATE540681T1 (de) | 2006-06-26 | 2012-01-15 | Amgen Inc | Verfahren zur behandlung von atherosklerose |
| JP2010502615A (ja) | 2006-09-01 | 2010-01-28 | メルク エンド カムパニー インコーポレーテッド | ５−リポキシゲナーゼ活性化タンパク質（ｆｌａｐ）の阻害剤 |
| CA2683948A1 (en) | 2007-04-20 | 2008-10-30 | Merck Frosst Canada Ltd. | Novel heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| AU2008266960A1 (en) | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | Diphenyl substituted alkanes |
| EP2209761A4 (en) | 2007-10-10 | 2012-01-04 | Merck Sharp & Dohme | DIPHENYL-SUBSTITUTED CYCLOAL CANS |
| US8598209B2 (en) * | 2008-10-31 | 2013-12-03 | Merck Sharp & Dohme Corp. | P2X3, receptor antagonists for treatment of pain |
| EP2393811A1 (en) | 2009-02-04 | 2011-12-14 | Pfizer Inc. | 4-amino-7,8-dihydropyrido[4,3-d]pyrimidin-5(6h)-one derivatives |
| RU2012154447A (ru) | 2010-05-12 | 2014-06-20 | Вандербилт Юниверсити | Гетероциклические сульфоновые аллостерические потенциаторы mglur4, композиции и способы лечения неврологических дисфункций |
| AU2011292285A1 (en) * | 2010-08-16 | 2013-01-31 | Boehringer Ingelheim International Gmbh | Oxadiazole inhibitors of leukotriene production |
| EP2609092B1 (en) | 2010-08-26 | 2015-04-01 | Boehringer Ingelheim International GmbH | Oxadiazole inhibitors of leukotriene production |
| US8580825B2 (en) * | 2010-09-23 | 2013-11-12 | Boehringer Ingelheim International Gmbh | Oxadiazole inhibitors of leukotriene production |
| BR112013008638A2 (pt) * | 2010-09-23 | 2016-06-21 | Boehringer Ingelheim Int | inibidores de oxadiazol de produção de leucotrieno |
-
2011
- 2011-08-23 EP EP11749686.9A patent/EP2609092B1/en active Active
- 2011-08-23 JP JP2013526084A patent/JP5862669B2/ja active Active
- 2011-08-23 WO PCT/US2011/048743 patent/WO2012027322A1/en not_active Ceased
- 2011-08-23 US US13/215,654 patent/US8580829B2/en active Active