JP2013536180A5 - - Google Patents

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Publication number
JP2013536180A5
JP2013536180A5 JP2013521998A JP2013521998A JP2013536180A5 JP 2013536180 A5 JP2013536180 A5 JP 2013536180A5 JP 2013521998 A JP2013521998 A JP 2013521998A JP 2013521998 A JP2013521998 A JP 2013521998A JP 2013536180 A5 JP2013536180 A5 JP 2013536180A5
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JP
Japan
Prior art keywords
growth factor
protein
factor
soluble polymer
group
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Application number
JP2013521998A
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English (en)
Japanese (ja)
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JP6325818B2 (ja
JP2013536180A (ja
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Priority claimed from PCT/US2011/045873 external-priority patent/WO2012016131A1/en
Publication of JP2013536180A publication Critical patent/JP2013536180A/ja
Publication of JP2013536180A5 publication Critical patent/JP2013536180A5/ja
Application granted granted Critical
Publication of JP6325818B2 publication Critical patent/JP6325818B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013521998A 2010-07-30 2011-07-29 オキシム連結のための求核触媒 Active JP6325818B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36918610P 2010-07-30 2010-07-30
US61/369,186 2010-07-30
PCT/US2011/045873 WO2012016131A1 (en) 2010-07-30 2011-07-29 Nucleophilic catalysts for oxime linkage

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015118007A Division JP2015164958A (ja) 2010-07-30 2015-06-11 オキシム連結のための求核触媒

Publications (3)

Publication Number Publication Date
JP2013536180A JP2013536180A (ja) 2013-09-19
JP2013536180A5 true JP2013536180A5 (https=) 2018-04-12
JP6325818B2 JP6325818B2 (ja) 2018-05-16

Family

ID=44629987

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2013521998A Active JP6325818B2 (ja) 2010-07-30 2011-07-29 オキシム連結のための求核触媒
JP2015118007A Withdrawn JP2015164958A (ja) 2010-07-30 2015-06-11 オキシム連結のための求核触媒
JP2017099807A Withdrawn JP2017137358A (ja) 2010-07-30 2017-05-19 オキシム連結のための求核触媒
JP2019064338A Withdrawn JP2019116501A (ja) 2010-07-30 2019-03-28 オキシム連結のための求核触媒
JP2019064337A Active JP6757823B2 (ja) 2010-07-30 2019-03-28 オキシム連結のための求核触媒
JP2020196260A Active JP7054407B2 (ja) 2010-07-30 2020-11-26 オキシム連結のための求核触媒
JP2021212106A Active JP7258999B2 (ja) 2010-07-30 2021-12-27 オキシム連結のための求核触媒

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2015118007A Withdrawn JP2015164958A (ja) 2010-07-30 2015-06-11 オキシム連結のための求核触媒
JP2017099807A Withdrawn JP2017137358A (ja) 2010-07-30 2017-05-19 オキシム連結のための求核触媒
JP2019064338A Withdrawn JP2019116501A (ja) 2010-07-30 2019-03-28 オキシム連結のための求核触媒
JP2019064337A Active JP6757823B2 (ja) 2010-07-30 2019-03-28 オキシム連結のための求核触媒
JP2020196260A Active JP7054407B2 (ja) 2010-07-30 2020-11-26 オキシム連結のための求核触媒
JP2021212106A Active JP7258999B2 (ja) 2010-07-30 2021-12-27 オキシム連結のための求核触媒

Country Status (26)

Country Link
EP (3) EP4023247A1 (https=)
JP (7) JP6325818B2 (https=)
KR (6) KR102172133B1 (https=)
CN (3) CN108079312A (https=)
AR (1) AR082941A1 (https=)
AU (1) AU2011282571C1 (https=)
BR (1) BR112013001611B1 (https=)
CA (1) CA2806684C (https=)
CY (1) CY1121943T1 (https=)
DK (1) DK2598172T3 (https=)
EA (2) EA025738B9 (https=)
ES (1) ES2731626T3 (https=)
HR (1) HRP20190990T1 (https=)
HU (1) HUE043790T2 (https=)
LT (1) LT2598172T (https=)
MX (1) MX346271B (https=)
NZ (1) NZ605972A (https=)
PL (1) PL2598172T3 (https=)
PT (1) PT2598172T (https=)
RS (1) RS58900B1 (https=)
SG (2) SG10201913078SA (https=)
SI (1) SI2598172T1 (https=)
SM (1) SMT201900351T1 (https=)
TR (1) TR201908836T4 (https=)
TW (1) TWI534152B (https=)
WO (1) WO2012016131A1 (https=)

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US8809501B2 (en) 2009-07-27 2014-08-19 Baxter International Inc. Nucleophilic catalysts for oxime linkage
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HUE049352T2 (hu) 2010-12-22 2020-09-28 Baxalta GmbH Anyagok és módszerek egy vízoldható zsírsavszármazéknak egy fehérjéhez való konjugálására
MY190257A (en) * 2012-04-16 2022-04-11 Cantab Biopharmaceuticals Patents Ltd Optimised subcutaneous therapeutic agents
AU2013204754C1 (en) * 2012-05-16 2018-10-11 Takeda Pharmaceutical Company Limited Nucleophilic Catalysts for Oxime Linkage
MA39711A (fr) * 2014-04-03 2015-10-08 Nektar Therapeutics Conjugués d'une fraction d'il-15 et d'un polymère
AU2016335860B2 (en) 2015-10-08 2023-08-10 Nektar Therapeutics Combination of an IL-2Rbeta-selective agonist and a long-acting IL-15 agonist
CA3007364A1 (en) * 2015-12-03 2017-06-08 Baxalta Incorporated Factor viii with extended half-life and reduced ligand-binding properties
JP7618383B2 (ja) * 2016-07-22 2025-01-21 ネクター セラピューティクス オキシム含有リンケージを有する第ｖｉｉｉ因子部分のコンジュゲート
US12036283B2 (en) 2017-05-15 2024-07-16 Nektar Therapeutics Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods
JP2022523301A (ja) 2019-01-23 2022-04-22 リジェネロン・ファーマシューティカルズ・インコーポレイテッド アンジオポエチン様７（ａｎｇｐｔｌ７）阻害剤による眼疾患の治療
US11845989B2 (en) 2019-01-23 2023-12-19 Regeneron Pharmaceuticals, Inc. Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors
WO2022182768A1 (en) 2021-02-26 2022-09-01 Regeneron Pharmaceuticals, Inc. Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors
WO2025133203A1 (en) * 2023-12-22 2025-06-26 Pam Theragnostics Gmbh Compounds and methods for a long-lasting pam

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DK2598172T3 (da) * 2010-07-30 2019-07-01 Baxalta GmbH Nukleofile katalysatorer til oximforbindelse

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