JP2013535508A - 抗体付きアジュバントを抗原提示細胞に直接的に標的化することをベースにした新規ワクチンアジュバント - Google Patents
抗体付きアジュバントを抗原提示細胞に直接的に標的化することをベースにした新規ワクチンアジュバント Download PDFInfo
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- JP2013535508A JP2013535508A JP2013524253A JP2013524253A JP2013535508A JP 2013535508 A JP2013535508 A JP 2013535508A JP 2013524253 A JP2013524253 A JP 2013524253A JP 2013524253 A JP2013524253 A JP 2013524253A JP 2013535508 A JP2013535508 A JP 2013535508A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/106—Vibrio; Campylobacter; Not used, see subgroups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37376310P | 2010-08-13 | 2010-08-13 | |
| US61/373,763 | 2010-08-13 | ||
| PCT/US2011/047633 WO2012021834A1 (en) | 2010-08-13 | 2011-08-12 | Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013535508A true JP2013535508A (ja) | 2013-09-12 |
| JP2013535508A5 JP2013535508A5 (https=) | 2014-09-25 |
Family
ID=45564978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013524253A Pending JP2013535508A (ja) | 2010-08-13 | 2011-08-12 | 抗体付きアジュバントを抗原提示細胞に直接的に標的化することをベースにした新規ワクチンアジュバント |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20120039916A1 (https=) |
| EP (1) | EP2603235A4 (https=) |
| JP (1) | JP2013535508A (https=) |
| KR (1) | KR20130108295A (https=) |
| CN (1) | CN103328005A (https=) |
| AR (1) | AR082686A1 (https=) |
| AU (1) | AU2011289234B2 (https=) |
| BR (1) | BR112013002940A2 (https=) |
| CA (1) | CA2807585A1 (https=) |
| MX (1) | MX2013001527A (https=) |
| RU (1) | RU2013110889A (https=) |
| TW (1) | TWI506035B (https=) |
| WO (1) | WO2012021834A1 (https=) |
| ZA (1) | ZA201301013B (https=) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017507922A (ja) * | 2014-01-22 | 2017-03-23 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 抗体のためおよび抗体が充填された樹状細胞を介した療法のための方法および組成物 |
| JP2017525655A (ja) * | 2014-06-02 | 2017-09-07 | ベイラー リサーチ インスティテュートBaylor Research Institute | アレルギーおよび炎症性疾患を治療するための方法および組成物 |
| JP2019506372A (ja) * | 2015-12-15 | 2019-03-07 | アンスティトゥート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシャルシュ・メディカル・(インセルム) | Ebv細胞抗原及びターゲティング部分を含む免疫原性構築物並びにその適用 |
| JP2020526482A (ja) * | 2017-06-28 | 2020-08-31 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | デクチン−2刺激及び癌免疫療法のための方法及び組成物 |
| US11110178B2 (en) | 2016-07-07 | 2021-09-07 | The Board Of Trustees Of The Leland Standford Junior University | Antibody adjuvant conjugates |
| JP2022518771A (ja) * | 2019-01-22 | 2022-03-16 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 抗原提示好中球由来樹状細胞およびその使用方法 |
| US11400164B2 (en) | 2019-03-15 | 2022-08-02 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting HER2 |
| JP2023502712A (ja) * | 2019-11-21 | 2023-01-25 | インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) | 抗pd-1/il-15免疫サイトカインによる新しいpd-1標的免疫療法 |
| JP2023549555A (ja) * | 2020-11-18 | 2023-11-27 | パイオニア イミュノセラピューティクス インコーポレイテッド | 抗marco抗体及びその使用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI422594B (zh) | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
| EP2150276B1 (en) * | 2007-05-03 | 2014-05-21 | Agency For Science, Technology And Research | Antibodies binding to an intracellular prl-1 or prl-3 polypeptide |
| TW201247706A (en) * | 2011-03-08 | 2012-12-01 | Baylor Res Inst | Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells |
| WO2013033104A1 (en) * | 2011-08-29 | 2013-03-07 | Baylor Research Institute | CONTROLLING ALLERGY AND ASTHMA BY ACTIVATING HUMAN DCs VIA DECTIN-1 OR DECTIN-1 AND TOLL-LIKE RECEPTOR 2 (TLR2) |
| US20150359874A1 (en) * | 2012-03-05 | 2015-12-17 | Duke University | Vaccine formulation |
| CN112587671A (zh) | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| WO2014031984A1 (en) * | 2012-08-24 | 2014-02-27 | Baylor Research Institute | Immunological detection methods and compositions |
| CN105555303A (zh) | 2013-06-28 | 2016-05-04 | 贝勒研究院 | 用于多发性硬化症的树突细胞asgpr靶向免疫治疗剂 |
| CN103409451A (zh) * | 2013-06-28 | 2013-11-27 | 扬州维克斯生物科技有限公司 | 一种向树突状细胞dc靶向加载肿瘤抗原肽的方法 |
| JP2016529909A (ja) * | 2013-09-05 | 2016-09-29 | デューク ユニバーシティ | Nav1.7抗体及び前記抗体を使用する方法 |
| DK3092256T3 (da) | 2014-01-10 | 2022-06-20 | Birdie Biopharmaceuticals Inc | Forbindelser og sammensætninger til immunterapi |
| CN120939216A (zh) | 2014-01-13 | 2025-11-14 | 贝勒研究院 | 抗hpv和hpv相关的疾病的新疫苗 |
| WO2015175957A1 (en) | 2014-05-16 | 2015-11-19 | Baylor Research Institute | Methods and compositions for treating autoimmune and inflammatory conditions |
| WO2016001810A1 (en) | 2014-07-01 | 2016-01-07 | Pfizer Inc. | Bispecific heterodimeric diabodies and uses thereof |
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| WO2016179034A2 (en) * | 2015-05-01 | 2016-11-10 | The Trustees Of The University Of Pennsylvania | Methods and compositions for stimulating immune response using potent immunostimulatory rna motifs |
| EP3368092B9 (en) | 2015-10-29 | 2020-07-29 | Novartis AG | Antibody conjugates comprising toll-like receptor agonist |
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| CN106943597A (zh) | 2016-01-07 | 2017-07-14 | 博笛生物科技(北京)有限公司 | 用于治疗肿瘤的抗-egfr组合 |
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| US20190336615A1 (en) * | 2017-01-27 | 2019-11-07 | Silverback Therapeutics, Inc. | Tumor targeting conjugates and methods of use thereof |
| CN108727503A (zh) * | 2017-04-18 | 2018-11-02 | 武汉博沃生物科技有限公司 | VZV重组gE-鞭毛素融合蛋白及其制备方法和应用 |
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| JP7735291B2 (ja) | 2020-02-21 | 2025-09-08 | エーアールエス ファーマシューティカルズ、インコーポレイテッド | ネクチン-4抗体コンジュゲートおよびその使用 |
| US20230183366A1 (en) | 2020-05-13 | 2023-06-15 | Inserm (Institut National De La Santé Et De La Recherch Médicale) | Recombinant proteins with ox40 activating properties |
| MX2022014943A (es) | 2020-05-26 | 2023-03-08 | Inst Nat Sante Rech Med | Polipéptidos de coronavirus 2 causante del síndrome respiratorio agudo severo (sars-cov-2) y usos de los mismos para propositos de vacuna. |
| MX2022015157A (es) | 2020-06-02 | 2023-01-16 | Arcus Biosciences Inc | Anticuerpos para tigit. |
| JP2023532304A (ja) | 2020-07-01 | 2023-07-27 | エーアールエス ファーマシューティカルズ オペレーションズ,インク. | 抗asgr1抗体コンジュゲートおよびその使用 |
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| MX2023005570A (es) | 2020-11-12 | 2023-05-29 | Inst Nat Sante Rech Med | Anticuerpos conjugados o fusionados al dominio de union del receptor de la proteina de la espicula de sars-cov-2 y usos de los mismos con fines de vacunacion. |
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| EP4426747A4 (en) * | 2021-11-04 | 2025-10-15 | Massachusetts Gen Hospital | ANTI-MESOTHELIN ANTIBODY REAGENTS |
| WO2023088968A1 (en) | 2021-11-17 | 2023-05-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Universal sarbecovirus vaccines |
| WO2024074571A1 (en) | 2022-10-05 | 2024-04-11 | Institut National de la Santé et de la Recherche Médicale | Dc-targeting vaccine against nipah virus infection |
| EP4601682A1 (en) * | 2022-10-13 | 2025-08-20 | The Brigham & Women's Hospital, Inc. | Methods and compositions for improving response to immunotherapy |
| KR102878250B1 (ko) * | 2023-01-11 | 2025-10-31 | 서울대학교산학협력단 | 코리스메이트 뮤테이즈 단백질 또는 이를 암호화하는 폴리뉴클레오티드를 포함하는 암 예방 또는 치료용 조성물 |
| EP4695289A1 (en) * | 2023-04-13 | 2026-02-18 | The Regents of the University of California | Isoform-independent antibodies to lipoprotein(a) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006502080A (ja) * | 2001-11-27 | 2006-01-19 | シェーリング コーポレイション | 腫瘍由来樹状細胞阻害因子アンタゴニストおよびToll様レセプターアゴニストの併用を使用する、癌を処置するための方法 |
| WO2007103048A2 (en) * | 2006-03-01 | 2007-09-13 | Regents Of The University Of Colorado | Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity |
| WO2008097866A2 (en) * | 2007-02-02 | 2008-08-14 | Baylor Research Institute | Vaccines based on targeting antigen to dcir expressed an antigen-presenting cells |
| JP2013525496A (ja) * | 2010-05-07 | 2013-06-20 | ベイラー リサーチ インスティテュート | ヒトcd8+t細胞の樹状細胞免疫受容体(dcir)媒介クロスプライミング |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057915C (zh) * | 1994-09-19 | 2000-11-01 | 中国医学科学院医药生物技术研究所 | 免疫佐剂 |
| US9259459B2 (en) * | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
| US8420102B2 (en) * | 2006-03-07 | 2013-04-16 | Vaxinnate Corporation | Compositions that include hemagglutinin |
| MX2009008926A (es) * | 2007-02-23 | 2009-09-14 | Baylor Res Inst | Aplicaciones terapeuticas de activacion de celulas que presentan antigeno humano por medio de detectina a-1. |
| CN101888856B (zh) * | 2007-11-07 | 2014-08-27 | 塞尔德克斯医疗公司 | 结合人树突和上皮细胞205(dec-205)的抗体 |
| ES2685823T3 (es) * | 2008-07-16 | 2018-10-11 | Baylor Research Institute | Anticuerpos antagonistas anti-CD40 |
| AU2010222942B2 (en) * | 2009-03-10 | 2013-01-10 | Baylor Research Institute | Anti-CD40 antibodies and uses thereof |
| CN102770457A (zh) * | 2009-03-10 | 2012-11-07 | 贝勒研究院 | 靶向抗原呈递细胞的疫苗 |
| DK2406289T3 (en) * | 2009-03-10 | 2017-05-01 | Baylor Res Inst | ANTIGEN PRESENTING CELL TARGETED ANTIVIRUS VACCINES |
-
2011
- 2011-08-12 KR KR1020137006354A patent/KR20130108295A/ko not_active Withdrawn
- 2011-08-12 TW TW100128970A patent/TWI506035B/zh not_active IP Right Cessation
- 2011-08-12 BR BR112013002940A patent/BR112013002940A2/pt not_active IP Right Cessation
- 2011-08-12 CN CN2011800489046A patent/CN103328005A/zh active Pending
- 2011-08-12 AR ARP110102955A patent/AR082686A1/es not_active Application Discontinuation
- 2011-08-12 EP EP11817128.9A patent/EP2603235A4/en not_active Withdrawn
- 2011-08-12 US US13/208,993 patent/US20120039916A1/en not_active Abandoned
- 2011-08-12 RU RU2013110889/10A patent/RU2013110889A/ru unknown
- 2011-08-12 MX MX2013001527A patent/MX2013001527A/es not_active Application Discontinuation
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- 2011-08-12 CA CA2807585A patent/CA2807585A1/en not_active Abandoned
- 2011-08-12 JP JP2013524253A patent/JP2013535508A/ja active Pending
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2013
- 2013-02-06 ZA ZA2013/01013A patent/ZA201301013B/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006502080A (ja) * | 2001-11-27 | 2006-01-19 | シェーリング コーポレイション | 腫瘍由来樹状細胞阻害因子アンタゴニストおよびToll様レセプターアゴニストの併用を使用する、癌を処置するための方法 |
| WO2007103048A2 (en) * | 2006-03-01 | 2007-09-13 | Regents Of The University Of Colorado | Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity |
| WO2008097866A2 (en) * | 2007-02-02 | 2008-08-14 | Baylor Research Institute | Vaccines based on targeting antigen to dcir expressed an antigen-presenting cells |
| JP2013525496A (ja) * | 2010-05-07 | 2013-06-20 | ベイラー リサーチ インスティテュート | ヒトcd8+t細胞の樹状細胞免疫受容体(dcir)媒介クロスプライミング |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017507922A (ja) * | 2014-01-22 | 2017-03-23 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 抗体のためおよび抗体が充填された樹状細胞を介した療法のための方法および組成物 |
| JP2017525655A (ja) * | 2014-06-02 | 2017-09-07 | ベイラー リサーチ インスティテュートBaylor Research Institute | アレルギーおよび炎症性疾患を治療するための方法および組成物 |
| JP2019506372A (ja) * | 2015-12-15 | 2019-03-07 | アンスティトゥート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシャルシュ・メディカル・(インセルム) | Ebv細胞抗原及びターゲティング部分を含む免疫原性構築物並びにその適用 |
| US11147868B2 (en) | 2015-12-15 | 2021-10-19 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Immunogenic construct comprising an EBV-cell antigen and a targeting moiety and applications thereof |
| US11547761B1 (en) | 2016-07-07 | 2023-01-10 | The Board Of Trustees Of The Leland Stanford Junior University | Antibody adjuvant conjugates |
| US11110178B2 (en) | 2016-07-07 | 2021-09-07 | The Board Of Trustees Of The Leland Standford Junior University | Antibody adjuvant conjugates |
| JP2020526482A (ja) * | 2017-06-28 | 2020-08-31 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | デクチン−2刺激及び癌免疫療法のための方法及び組成物 |
| JP2022518771A (ja) * | 2019-01-22 | 2022-03-16 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 抗原提示好中球由来樹状細胞およびその使用方法 |
| JP7670614B2 (ja) | 2019-01-22 | 2025-04-30 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 抗原提示好中球由来樹状細胞およびその使用方法 |
| US12589140B2 (en) | 2019-01-22 | 2026-03-31 | The Brigham And Women's Hospital, Inc. | Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof |
| US11400164B2 (en) | 2019-03-15 | 2022-08-02 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting HER2 |
| JP2023502712A (ja) * | 2019-11-21 | 2023-01-25 | インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) | 抗pd-1/il-15免疫サイトカインによる新しいpd-1標的免疫療法 |
| JP2023549555A (ja) * | 2020-11-18 | 2023-11-27 | パイオニア イミュノセラピューティクス インコーポレイテッド | 抗marco抗体及びその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| TW201208696A (en) | 2012-03-01 |
| AU2011289234B2 (en) | 2014-09-11 |
| US20120039916A1 (en) | 2012-02-16 |
| RU2013110889A (ru) | 2014-09-20 |
| KR20130108295A (ko) | 2013-10-02 |
| TWI506035B (zh) | 2015-11-01 |
| AU2011289234A1 (en) | 2013-02-21 |
| ZA201301013B (en) | 2015-10-28 |
| BR112013002940A2 (pt) | 2019-09-24 |
| EP2603235A1 (en) | 2013-06-19 |
| CN103328005A (zh) | 2013-09-25 |
| CA2807585A1 (en) | 2012-02-16 |
| AR082686A1 (es) | 2012-12-26 |
| WO2012021834A1 (en) | 2012-02-16 |
| EP2603235A4 (en) | 2014-04-09 |
| MX2013001527A (es) | 2013-04-24 |
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