JP2013535218A5 - - Google Patents
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- Publication number
- JP2013535218A5 JP2013535218A5 JP2013523627A JP2013523627A JP2013535218A5 JP 2013535218 A5 JP2013535218 A5 JP 2013535218A5 JP 2013523627 A JP2013523627 A JP 2013523627A JP 2013523627 A JP2013523627 A JP 2013523627A JP 2013535218 A5 JP2013535218 A5 JP 2013535218A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- cytotoxic
- dendritic cells
- immature dendritic
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 11
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 210000004443 dendritic cell Anatomy 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 5
- 210000002966 serum Anatomy 0.000 claims 4
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 3
- 210000001744 T-lymphocyte Anatomy 0.000 claims 3
- 231100000433 cytotoxic Toxicity 0.000 claims 3
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 3
- 230000001472 cytotoxic effect Effects 0.000 claims 3
- 229920000669 heparin Polymers 0.000 claims 3
- 238000009169 immunotherapy Methods 0.000 claims 3
- 210000001616 monocyte Anatomy 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 229960002897 heparin Drugs 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 239000002609 medium Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000012460 protein solution Substances 0.000 claims 2
- 238000001179 sorption measurement Methods 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 230000004913 activation Effects 0.000 claims 1
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 1
- 230000003796 beauty Effects 0.000 claims 1
- 238000002659 cell therapy Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1013443.5 | 2010-08-11 | ||
| GBGB1013443.5A GB201013443D0 (en) | 2010-08-11 | 2010-08-11 | Compositions and methods for producing dendritic cells |
| PCT/EP2011/063867 WO2012020100A2 (en) | 2010-08-11 | 2011-08-11 | Compositions and methods for producing dendritic cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013535218A JP2013535218A (ja) | 2013-09-12 |
| JP2013535218A5 true JP2013535218A5 (enExample) | 2014-09-25 |
| JP6060077B2 JP6060077B2 (ja) | 2017-01-11 |
Family
ID=42931452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523627A Expired - Fee Related JP6060077B2 (ja) | 2010-08-11 | 2011-08-11 | 樹状細胞を産生するための組成物及び方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9567567B2 (enExample) |
| EP (1) | EP2603582B1 (enExample) |
| JP (1) | JP6060077B2 (enExample) |
| KR (1) | KR20130103492A (enExample) |
| CN (1) | CN103201378B (enExample) |
| AU (1) | AU2011288416B2 (enExample) |
| BR (1) | BR112013003385A2 (enExample) |
| CA (1) | CA2807892A1 (enExample) |
| EA (1) | EA201390215A1 (enExample) |
| GB (1) | GB201013443D0 (enExample) |
| SG (1) | SG187839A1 (enExample) |
| WO (1) | WO2012020100A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102925412A (zh) * | 2012-11-19 | 2013-02-13 | 昆明理工大学附属医院 | 一种制备肿瘤特异性抗原致敏dc的方法 |
| US10532088B2 (en) | 2014-02-27 | 2020-01-14 | Lycera Corporation | Adoptive cellular therapy using an agonist of retinoic acid receptor-related orphan receptor gamma and related therapeutic methods |
| US9896441B2 (en) | 2014-05-05 | 2018-02-20 | Lycera Corporation | Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
| US10421751B2 (en) | 2015-05-05 | 2019-09-24 | Lycera Corporation | Dihydro-2H-benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
| WO2016201225A1 (en) | 2015-06-11 | 2016-12-15 | Lycera Corporation | Aryl dihydro-2h-benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of rory and the treatment of disease |
| CN105039256A (zh) * | 2015-07-13 | 2015-11-11 | 中政道和（北京）生物科技有限公司 | 一种支气管镜下获取肿瘤组织进行树突细胞培养扩增方法 |
| US11976299B2 (en) * | 2016-09-23 | 2024-05-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of preparing an isolated population of dendritic cells and methods of treating cancer using same |
| WO2019144047A1 (en) * | 2018-01-18 | 2019-07-25 | University Of South Florida | Dead antigen stimulated immature heterogenous dendritic cells as therapeutics for diseases |
| CN112703004B (zh) * | 2018-07-15 | 2025-02-14 | 雷诺瓦罗生物制药公司 | 使用重组树突状细胞用于癌症治疗的方法和组合物 |
| US12282027B2 (en) | 2021-02-19 | 2025-04-22 | University Of South Florida | High-throughput NMR approach for in-membrane protein ligand screening |
| WO2025076303A1 (en) * | 2023-10-05 | 2025-04-10 | Amgen Inc. | Major histocompatibility complex (mhc)-associated peptide proteomics (mapps) assay for immunogenicity risk assessment of biotherapeutic attributes |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6458585B1 (en) | 1996-08-14 | 2002-10-01 | Nexell Therapeutics Inc. | Cytokine-free culture of dendritic cells |
| GB9617058D0 (en) * | 1996-08-14 | 1996-09-25 | Sandoz Ltd | Organic compounds |
| AUPO388396A0 (en) | 1996-11-27 | 1996-12-19 | Ludwig Institute For Cancer Research | Cellular adjuvant |
| ATE446106T1 (de) * | 2001-11-29 | 2009-11-15 | Dandrit Biotech As | Pharmazeutische zusammensetzung zur auslösung einer immunantwort bei einem menschen oder einem tier |
| US20060216269A1 (en) * | 2004-09-17 | 2006-09-28 | Kenichiro Hasumi | Dendritic cell tumor injection (DCTI) therapy |
| GB0700058D0 (en) | 2007-01-03 | 2007-02-07 | Scancell Aps | Anti-tumor vaccine based on normal cells |
| JP5279063B2 (ja) | 2007-05-25 | 2013-09-04 | 国立大学法人愛媛大学 | Ｈｌａ−ａ２拘束性抗原ペプチドおよびその用途 |
| JP2009013166A (ja) | 2007-06-04 | 2009-01-22 | Osaka Prefecture Univ | 腫瘍治療用組成物およびその応用 |
-
2010
- 2010-08-11 GB GBGB1013443.5A patent/GB201013443D0/en not_active Ceased
-
2011
- 2011-08-11 KR KR1020137004865A patent/KR20130103492A/ko not_active Ceased
- 2011-08-11 BR BR112013003385A patent/BR112013003385A2/pt not_active IP Right Cessation
- 2011-08-11 WO PCT/EP2011/063867 patent/WO2012020100A2/en not_active Ceased
- 2011-08-11 JP JP2013523627A patent/JP6060077B2/ja not_active Expired - Fee Related
- 2011-08-11 SG SG2013010855A patent/SG187839A1/en unknown
- 2011-08-11 US US13/816,359 patent/US9567567B2/en not_active Expired - Fee Related
- 2011-08-11 CN CN201180046061.6A patent/CN103201378B/zh not_active Expired - Fee Related
- 2011-08-11 CA CA2807892A patent/CA2807892A1/en not_active Abandoned
- 2011-08-11 AU AU2011288416A patent/AU2011288416B2/en not_active Ceased
- 2011-08-11 EA EA201390215A patent/EA201390215A1/ru unknown
- 2011-08-11 EP EP11749387.4A patent/EP2603582B1/en not_active Not-in-force
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