JP2013534228A5 - - Google Patents

Info

Publication number

JP2013534228A5

JP2013534228A5 JP2013524368A JP2013524368A JP2013534228A5 JP 2013534228 A5 JP2013534228 A5 JP 2013534228A5 JP 2013524368 A JP2013524368 A JP 2013524368A JP 2013524368 A JP2013524368 A JP 2013524368A JP 2013534228 A5 JP2013534228 A5 JP 2013534228A5

Authority

JP

Japan

Prior art keywords

testosterone

solution

solution according

testosterone solution

ethanol

Prior art date

2011-08-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 86
• 229960003604 testosterone Drugs 0.000 claims 43
• 239000000243 solution Substances 0.000 claims 37
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 20
• HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims 5
• WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical class OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims 3
• 239000000654 additive Substances 0.000 claims 2
• 239000007864 aqueous solution Substances 0.000 claims 2
• 230000003247 decreasing effect Effects 0.000 claims 2
• 235000014113 dietary fatty acids Nutrition 0.000 claims 2
• 229930195729 fatty acid Natural products 0.000 claims 2
• 239000000194 fatty acid Substances 0.000 claims 2
• 238000006467 substitution reaction Methods 0.000 claims 2
• 206010002261 Androgen deficiency Diseases 0.000 claims 1
• 206010012374 Depressed mood Diseases 0.000 claims 1
• 208000001132 Osteoporosis Diseases 0.000 claims 1
• 208000014993 Pituitary disease Diseases 0.000 claims 1
• 210000000988 bone and bone Anatomy 0.000 claims 1
• 230000027288 circadian rhythm Effects 0.000 claims 1
• 230000003920 cognitive function Effects 0.000 claims 1
• 201000010099 disease Diseases 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 150000002148 esters Chemical class 0.000 claims 1
• 210000003205 muscle Anatomy 0.000 claims 1
• 208000017402 pituitary gland disease Diseases 0.000 claims 1
• 230000001568 sexual effect Effects 0.000 claims 1
• 230000021595 spermatogenesis Effects 0.000 claims 1
• 238000005507 spraying Methods 0.000 claims 1
• 230000001629 suppression Effects 0.000 claims 1
• 208000024891 symptom Diseases 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1