JP2013529916A5 - - Google Patents
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- Publication number
- JP2013529916A5 JP2013529916A5 JP2013514731A JP2013514731A JP2013529916A5 JP 2013529916 A5 JP2013529916 A5 JP 2013529916A5 JP 2013514731 A JP2013514731 A JP 2013514731A JP 2013514731 A JP2013514731 A JP 2013514731A JP 2013529916 A5 JP2013529916 A5 JP 2013529916A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- excluded
- peptide
- amino acid
- peptide according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000009304 Acute Kidney Injury Diseases 0.000 claims 2
- 208000010718 Multiple Organ Failure Diseases 0.000 claims 2
- 208000033626 Renal failure acute Diseases 0.000 claims 2
- 206010051379 Systemic Inflammatory Response Syndrome Diseases 0.000 claims 2
- 208000010285 Ventilator-Induced Lung Injury Diseases 0.000 claims 2
- 201000011040 acute kidney failure Diseases 0.000 claims 2
- 206010069351 acute lung injury Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 1
- 208000034486 Multi-organ failure Diseases 0.000 claims 1
- 206010030113 Oedema Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000008497 endothelial barrier function Effects 0.000 claims 1
- 230000004890 epithelial barrier function Effects 0.000 claims 1
- 108010001279 glycyl-arginyl-arginyl-prolyl-leucyl-glycyl-glycyl-isoleucyl-seryl-glycyl-glycine Proteins 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 claims 1
- 102000007268 rho GTP-Binding Proteins Human genes 0.000 claims 1
- 108010033674 rho GTP-Binding Proteins Proteins 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT10102010 | 2010-06-18 | ||
| ATA1010/2010 | 2010-06-18 | ||
| PCT/EP2011/060105 WO2011157819A2 (en) | 2010-06-18 | 2011-06-17 | Peptides as active agents to stabilize biological barriers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013529916A JP2013529916A (ja) | 2013-07-25 |
| JP2013529916A5 true JP2013529916A5 (enExample) | 2014-06-26 |
| JP5709985B2 JP5709985B2 (ja) | 2015-04-30 |
Family
ID=44628513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013514731A Expired - Fee Related JP5709985B2 (ja) | 2010-06-18 | 2011-06-17 | 生体バリアを安定化させる活性剤としてのペプチド |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9012403B2 (enExample) |
| EP (1) | EP2582720B1 (enExample) |
| JP (1) | JP5709985B2 (enExample) |
| CN (1) | CN103038253A (enExample) |
| CA (1) | CA2802635A1 (enExample) |
| ES (1) | ES2486321T3 (enExample) |
| RU (1) | RU2012157399A (enExample) |
| WO (1) | WO2011157819A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103068400A (zh) | 2010-06-25 | 2013-04-24 | 阿斯顿大学 | 具有脂类动员性质的糖蛋白及其治疗用途 |
| WO2015022326A1 (en) | 2013-08-12 | 2015-02-19 | Xiber Science Gmbh | Peptides as active agents for treating primary graft dysfunction |
| NL2015130B1 (en) * | 2015-07-09 | 2017-02-01 | Mimetas B V | Barrier function measurements. |
| KR102584300B1 (ko) * | 2016-03-29 | 2023-10-05 | 유니버시티 오브 써던 캘리포니아 | 암을 표적하는 키메라 항원 수용체 |
| CN112703009B (zh) * | 2018-08-17 | 2024-06-11 | 宾夕法尼亚大学董事会 | 治疗急性肺损伤的组合物和方法 |
| WO2020150300A1 (en) * | 2019-01-16 | 2020-07-23 | University Of Rochester | Improvement of epithelial or endothelial barrier function |
| WO2021148763A1 (en) | 2020-01-22 | 2021-07-29 | Ucl Business Ltd | Peptide inhibitors of guanine nucleotide exchange factor-h1 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4263428A (en) | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
| ATE12348T1 (de) | 1980-11-10 | 1985-04-15 | Gersonde Klaus Prof Dr | Verfahren zur herstellung von lipid-vesikeln durch ultraschallbehandlung, anwendung des verfahrens und vorrichtung zur durchfuehrung des verfahrens. |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| JPS58118008A (ja) | 1982-01-06 | 1983-07-13 | Nec Corp | デ−タ処理装置 |
| EP0088046B1 (de) | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
| DE3218121A1 (de) | 1982-05-14 | 1983-11-17 | Leskovar, Peter, Dr.-Ing., 8000 München | Arzneimittel zur tumorbehandlung |
| CA1223831A (en) | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| EP0102324A3 (de) | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipide und Tenside in wässriger Phase |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| EP0142641B1 (de) | 1983-09-26 | 1991-01-16 | Udo Dr. Ehrenfeld | Mittel und Erzeugnis für die Diagnose und Therapie von Tumoren sowie zur Behandlung von Schwächen der zelligen und humoralen Immunabwehr |
| DE3474511D1 (en) | 1983-11-01 | 1988-11-17 | Terumo Corp | Pharmaceutical composition containing urokinase |
| US5792608A (en) | 1991-12-12 | 1998-08-11 | Gilead Sciences, Inc. | Nuclease stable and binding competent oligomers and methods for their use |
| US5525711A (en) | 1994-05-18 | 1996-06-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Pteridine nucleotide analogs as fluorescent DNA probes |
| US6372250B1 (en) * | 2000-04-25 | 2002-04-16 | The Regents Of The University Of California | Non-invasive gene targeting to the brain |
| US20040053250A1 (en) * | 2001-03-05 | 2004-03-18 | Tang Y. Tom | Novel arginine-rich protein-like nucleic acids and polypeptides |
| DE60326453D1 (de) * | 2002-07-03 | 2009-04-16 | Ct Cardiologico Monzino S P A | Die verwendung von hmgb1 zur behandlung von gewebeverletzungen und/oder zur unterstützung der gewebewiederherstellung |
| CA2644712C (en) | 2006-03-06 | 2016-09-13 | Amunix, Inc. | Unstructured recombinant polymers and uses thereof |
| CN101970678B (zh) | 2007-06-21 | 2014-08-20 | 慕尼黑科技大学 | 具有增加的体内和/或体外稳定性的生物学活性蛋白 |
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2011
- 2011-06-17 US US13/702,490 patent/US9012403B2/en not_active Expired - Fee Related
- 2011-06-17 CN CN2011800299272A patent/CN103038253A/zh active Pending
- 2011-06-17 JP JP2013514731A patent/JP5709985B2/ja not_active Expired - Fee Related
- 2011-06-17 CA CA2802635A patent/CA2802635A1/en not_active Abandoned
- 2011-06-17 WO PCT/EP2011/060105 patent/WO2011157819A2/en not_active Ceased
- 2011-06-17 ES ES11732400.4T patent/ES2486321T3/es active Active
- 2011-06-17 RU RU2012157399/04A patent/RU2012157399A/ru not_active Application Discontinuation
- 2011-06-17 EP EP11732400.4A patent/EP2582720B1/en not_active Not-in-force