JP2013527168A5 - - Google Patents
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- JP2013527168A5 JP2013527168A5 JP2013508244A JP2013508244A JP2013527168A5 JP 2013527168 A5 JP2013527168 A5 JP 2013527168A5 JP 2013508244 A JP2013508244 A JP 2013508244A JP 2013508244 A JP2013508244 A JP 2013508244A JP 2013527168 A5 JP2013527168 A5 JP 2013527168A5
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- Prior art keywords
- pharmaceutical composition
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- 101000884271 Homo sapiens Signal transducer CD24 Proteins 0.000 claims description 29
- 102100038081 Signal transducer CD24 Human genes 0.000 claims description 25
- 239000013598 vector Substances 0.000 claims description 9
- 102000004169 proteins and genes Human genes 0.000 claims description 7
- 108090000623 proteins and genes Proteins 0.000 claims description 7
- 230000001177 retroviral effect Effects 0.000 claims description 5
- 102000044489 human CD24 Human genes 0.000 claims description 4
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims description 3
- 210000003527 eukaryotic cell Anatomy 0.000 claims description 3
- 206010039073 rheumatoid arthritis Diseases 0.000 claims description 3
- 108060003951 Immunoglobulin Proteins 0.000 claims description 2
- 241000124008 Mammalia Species 0.000 claims description 2
- 102000018358 immunoglobulin Human genes 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 235000018102 proteins Nutrition 0.000 claims 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 241001430294 unidentified retrovirus Species 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
- 230000002950 deficient Effects 0.000 description 3
- 230000010076 replication Effects 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32907810P | 2010-04-28 | 2010-04-28 | |
| US61/329,078 | 2010-04-28 | ||
| PCT/US2011/034282 WO2011139820A1 (en) | 2010-04-28 | 2011-04-28 | Methods of use of soluble cd24 for therapy of rheumatoid arthritis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015137457A Division JP6062502B2 (ja) | 2010-04-28 | 2015-07-09 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013527168A JP2013527168A (ja) | 2013-06-27 |
| JP2013527168A5 true JP2013527168A5 (cg-RX-API-DMAC7.html) | 2014-06-19 |
| JP5899206B2 JP5899206B2 (ja) | 2016-04-06 |
Family
ID=44903987
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508244A Expired - Fee Related JP5899206B2 (ja) | 2010-04-28 | 2011-04-28 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2015137457A Expired - Fee Related JP6062502B2 (ja) | 2010-04-28 | 2015-07-09 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2016242313A Withdrawn JP2017057216A (ja) | 2010-04-28 | 2016-12-14 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2018094404A Expired - Fee Related JP6526872B2 (ja) | 2010-04-28 | 2018-05-16 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2019088170A Expired - Fee Related JP6888221B2 (ja) | 2010-04-28 | 2019-05-08 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015137457A Expired - Fee Related JP6062502B2 (ja) | 2010-04-28 | 2015-07-09 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2016242313A Withdrawn JP2017057216A (ja) | 2010-04-28 | 2016-12-14 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2018094404A Expired - Fee Related JP6526872B2 (ja) | 2010-04-28 | 2018-05-16 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
| JP2019088170A Expired - Fee Related JP6888221B2 (ja) | 2010-04-28 | 2019-05-08 | 関節リウマチの治療のための可溶性ｃｄ２４の使用方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8808697B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2563385B1 (cg-RX-API-DMAC7.html) |
| JP (5) | JP5899206B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20130086126A (cg-RX-API-DMAC7.html) |
| CN (2) | CN105381451B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011248540B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2795823C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2563385T3 (cg-RX-API-DMAC7.html) |
| EA (2) | EA027735B1 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2645262T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL222739A0 (cg-RX-API-DMAC7.html) |
| NO (1) | NO2563385T3 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ603196A (cg-RX-API-DMAC7.html) |
| PL (2) | PL3260128T3 (cg-RX-API-DMAC7.html) |
| PT (2) | PT3260128T (cg-RX-API-DMAC7.html) |
| SG (1) | SG184907A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011139820A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130231464A1 (en) * | 2010-04-28 | 2013-09-05 | Oncolmmune, Inc. | Methods of use of soluble cd24 for therapy of rheumatoid arthritis |
| CN107531772B (zh) * | 2015-05-07 | 2021-09-21 | 肿瘤免疫股份有限公司 | Cd24用于降低低密度脂蛋白胆固醇水平的用途 |
| SG11201806338SA (en) * | 2016-02-02 | 2018-08-30 | Oncoimmune Inc | Use of cd24 proteins for treating leptin-deficient conditions |
| US10758574B2 (en) | 2016-04-28 | 2020-09-01 | The Board Of Trustees Of The Leland Stanford Junior University | Cartilage cells with a high regenerative potential and low immune response for use in cellular therapy |
| KR101789449B1 (ko) * | 2016-12-08 | 2017-10-23 | 박문수 | 폐유지를 이용한 지방산 메틸에스테르 제조방법 |
| CN110461353A (zh) * | 2017-03-07 | 2019-11-15 | 肿瘤免疫股份有限公司 | 可溶性cd24用于治疗系统性红斑狼疮的使用方法 |
| KR20200034957A (ko) * | 2017-05-15 | 2020-04-01 | 온코이뮨, 아이앤씨. | 신경 보호 및 재수초화를 위한 가용성 cd24의 사용 방법 |
| CN110799206A (zh) * | 2017-05-22 | 2020-02-14 | 肿瘤免疫股份有限公司 | 使用可溶性cd24治疗癌症疗法中免疫相关不良事件的方法 |
| AU2019231191A1 (en) * | 2018-03-05 | 2020-09-03 | Institute Of Biophysics, Chinese Academy Of Sciences | Methods of use of soluble CD24 for treating acquired immune deficiency syndrome (HIV/AIDS) |
| TWI835794B (zh) * | 2018-05-14 | 2024-03-21 | 美商昂科Ｃ４公司 | 抗cd24組合物及其用途 |
| EP3801773A4 (en) * | 2018-06-04 | 2022-03-16 | Oncoimmune, Inc. | METHOD OF USE OF CD24 FOR PREVENTION AND TREATMENT OF GRAFT VERSUS HOST DISEASE AND MUCOSITIS |
| EP4017508A1 (en) * | 2019-08-23 | 2022-06-29 | Sana Biotechnology, Inc. | Cd24 expressing cells and uses thereof |
| CN112480237B (zh) * | 2019-09-12 | 2023-10-17 | 上海津曼特生物科技有限公司 | 一种融合蛋白及其制备方法和应用 |
| US20250195673A1 (en) * | 2020-11-30 | 2025-06-19 | Fred Hutchinson Cancer Center | Compositions and methods for selective depletion of target molecules |
| EP4408862A4 (en) * | 2021-09-28 | 2025-11-12 | Acroimmune Guangzhou Biotech Ltd | Fusion proteins including the O71 core peptide and their use |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US5541087A (en) * | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| US5798448A (en) * | 1994-10-27 | 1998-08-25 | Genentech, Inc. | AL-1 neurotrophic factor antibodies |
| CN101254302B (zh) * | 1999-05-07 | 2011-05-11 | 杰南技术公司 | 使用与b细胞表面标志结合的拮抗剂治疗自身免疫病 |
| AU2001259792B2 (en) * | 2000-03-29 | 2005-12-22 | The Ohio State University Research Foundation | Methods of blocking tissue destruction by autoreactive T cells |
| US20030106084A1 (en) * | 2000-03-29 | 2003-06-05 | Yang Liu | Methods of blocking tissue destruction by autoreactive T cells |
| US20030095966A1 (en) * | 2000-03-29 | 2003-05-22 | Yang Liu | Method of blocking tissue destruction by autoreactive T cells |
| HUP0303171A2 (hu) * | 2001-02-19 | 2003-12-29 | Merck Patent Gmbh | Csökkentett immunogenitású mesterséges fehérjék |
| US20050214290A1 (en) * | 2001-03-29 | 2005-09-29 | Yang Liu | Methods of blocking tissue destruction by autoreactive T cells |
| CA2453406A1 (en) * | 2001-07-13 | 2003-01-23 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Methods for reducing immunogenicity of polypeptides |
| CA2505601C (en) * | 2002-11-15 | 2014-10-28 | Musc Foundation For Research Development | Complement receptor 2 targeted complement modulators |
| AU2007242919B8 (en) * | 2003-04-09 | 2011-11-10 | F. Hoffmann-La Roche Ag | Therapy of autoimmune disease in a patient with an inadequate response to a TNF-alpha inhibitor |
| NZ587776A (en) * | 2003-04-09 | 2012-03-30 | Genentech Inc | Therapy of autoimmune disease in a patient with an inadequate response to a TNF-alpha inhibitor using anti-CD20 antibody |
| EP1706507A4 (en) * | 2003-11-26 | 2008-02-20 | Univ Ohio State Res Found | THE RISK AND PROGRESSION OF MULTIPLE SCLEROSIS PREDICTING POLYMORPHS CD24 GENOTYPES |
| JP2008507591A (ja) * | 2004-05-21 | 2008-03-13 | ゼンコー・インコーポレイテッド | 免疫原性が改変されたＣ１ｑファミリーメンバータンパク質 |
| US20060160220A1 (en) * | 2004-11-12 | 2006-07-20 | Iogenetics | Retroviral vectors with introns |
-
2011
- 2011-04-28 CA CA2795823A patent/CA2795823C/en active Active
- 2011-04-28 PL PL17183045T patent/PL3260128T3/pl unknown
- 2011-04-28 PT PT171830458T patent/PT3260128T/pt unknown
- 2011-04-28 CN CN201510683408.8A patent/CN105381451B/zh not_active Expired - Fee Related
- 2011-04-28 CN CN201180021423.6A patent/CN102869369B/zh not_active Expired - Fee Related
- 2011-04-28 EA EA201290961A patent/EA027735B1/ru unknown
- 2011-04-28 EA EA201790538A patent/EA036805B8/ru unknown
- 2011-04-28 JP JP2013508244A patent/JP5899206B2/ja not_active Expired - Fee Related
- 2011-04-28 PL PL11778000T patent/PL2563385T3/pl unknown
- 2011-04-28 US US13/643,527 patent/US8808697B2/en active Active
- 2011-04-28 WO PCT/US2011/034282 patent/WO2011139820A1/en not_active Ceased
- 2011-04-28 ES ES11778000.7T patent/ES2645262T3/es active Active
- 2011-04-28 PT PT117780007T patent/PT2563385T/pt unknown
- 2011-04-28 AU AU2011248540A patent/AU2011248540B2/en not_active Ceased
- 2011-04-28 EP EP11778000.7A patent/EP2563385B1/en active Active
- 2011-04-28 ES ES17183045T patent/ES2826445T3/es active Active
- 2011-04-28 EP EP17183045.8A patent/EP3260128B1/en active Active
- 2011-04-28 SG SG2012077095A patent/SG184907A1/en unknown
- 2011-04-28 NZ NZ603196A patent/NZ603196A/en not_active IP Right Cessation
- 2011-04-28 KR KR1020127028301A patent/KR20130086126A/ko not_active Withdrawn
- 2011-04-28 NO NO11778000A patent/NO2563385T3/no unknown
- 2011-04-28 EP EP20188241.2A patent/EP3845238A1/en not_active Withdrawn
- 2011-04-28 DK DK11778000.7T patent/DK2563385T3/da active
-
2012
- 2012-10-28 IL IL222739A patent/IL222739A0/en active IP Right Grant
-
2015
- 2015-07-09 JP JP2015137457A patent/JP6062502B2/ja not_active Expired - Fee Related
-
2016
- 2016-12-14 JP JP2016242313A patent/JP2017057216A/ja not_active Withdrawn
-
2018
- 2018-05-16 JP JP2018094404A patent/JP6526872B2/ja not_active Expired - Fee Related
-
2019
- 2019-05-08 JP JP2019088170A patent/JP6888221B2/ja not_active Expired - Fee Related
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